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Your translated search: NADP+ = 5062 reactions were found.
State Icon Reaction EC-Number Conf. maximal confidence score from EnzymeDetector PW
Butyraldehyde + CoA + NADP+ <=> butyryl-CoA + NADPH + H+ 1.2.1.10 acetaldehyde dehydrogenase (acetylating)
1.2.1.57 butanal dehydrogenase
1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)
–
–
–
MK
D-glyceraldehyde_3-phosphate + phosphate + NADP+ <=> 3-phospho-D-glyceroyl_phosphate + NADPH + H+ 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)
1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
–
–
–
–
BMK
(3R)-2''-hydroxydihydrodaidzein + NADP+ <=> 2''-hydroxydaidzein + NADPH + H+ 1.3.1.51 2'-hydroxydaidzein reductase
–
MK
Precorrin-6Y + NADP+ <=> precorrin-6A + NADPH + H+ 1.3.1.54 precorrin-6A reductase
–
BMK
(R)-reticuline + NADP+ <=> 1,2-dehydroreticuline + NADPH + H+ 1.5.1.27 1,2-dehydroreticulinium reductase (NADPH)
–
MK
H+ + 1,4-benzoquinone + NADPH <=> hydroquinone + NADP+ 1.1.1.328 nicotine blue oxidoreductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
1.7.1.6 azobenzene reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
–
BMK
L-lysine + O2 + NADPH <=> N6-hydroxy-L-lysine + NADP+ + H2O 1.14.13.59 L-lysine N6-monooxygenase (NADPH)
–
BMK
9-fluorenol + NADP+ <=> 9-fluorenone + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.256 fluoren-9-ol dehydrogenase
–
–
MK
L-alpha-glycerophosphate + NADP+ <=> dihydroxyacetone_phosphate + NADPH + H+ 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.261 sn-glycerol-1-phosphate dehydrogenase
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+)
1.1.1.94 glycerol-3-phosphate dehydrogenase [NAD(P)+]
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
BMK
1,5-anhydro-D-glucitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+ 1.1.1.263 1,5-anhydro-D-fructose reductase
–
nitrite + H2O + NADP+ <=> H+ + nitrate + NADPH 1.7.1.1 nitrate reductase (NADH)
1.7.1.2 nitrate reductase [NAD(P)H]
1.7.1.3 nitrate reductase (NADPH)
–
–
–
MK
L-Idonate + NADP+ <=> 5-Dehydro-D-gluconate + NADPH + H+ 1.1.1.264 L-idonate 5-dehydrogenase
–
BM
3-methyl-1-butanol + NADP+ <=> Isovaleraldehyde + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
dTDP-alpha-D-fucopyranose + NADP+ <=> dTDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ 1.1.1.266 dTDP-4-dehydro-6-deoxyglucose reductase
1.1.1.B28
–
–
BMK
L-homoserine + NADP+ <=> L-aspartate_4-semialdehyde + NADPH + H+ 1.1.1.3 homoserine dehydrogenase
–
BMK
NO + O2 + NADPH <=> nitrate + NADP+ + H+ 1.14.12.17 nitric oxide dioxygenase
–
albendazole + O2 + NADPH + H+ <=> albendazole_S-oxide + H2O + NADP+ 1.14.13.32 albendazole monooxygenase
–
NADP+ + H+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> oxidized_ferredoxin + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.3 ferredoxin---NAD+ reductase
1.18.1.6 adrenodoxin-NADP+ reductase
–
–
–
M
xylitol + NADP+ <=> L-xylulose + NADPH + H+ 1.1.1.10 L-xylulose reductase
1.1.1.21 aldose reductase
1.1.1.B64
–
–
–
MK
(3R)-3-hydroxyacyl-[acyl-carrier_protein] + NADP+ <=> 3-oxoacyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
–
BMK
1-palmitoyl-sn-glycerol_3-phosphate + NADP+ <=> Palmitoyldihydroxyacetone_phosphate + NADPH + H+ 1.1.1.101 acylglycerone-phosphate reductase
–
sphinganine + NADP+ <=> 3-dehydrosphinganine + NADPH + H+ 1.1.1.102 3-dehydrosphinganine reductase
–
BMK
3-(imidazol-5-yl)lactate + NADP+ <=> 3-(1H-imidazol-4-yl)-2-oxopropanoate + NADPH + H+ 1.1.1.111 3-(imidazol-5-yl)lactate dehydrogenase
–
BM
1-Indanol + NADP+ <=> 1-Indanone + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.218 morphine 6-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
–
–
D-glucose + NADP+ <=> D-glucono-1,5-lactone + NADPH + H+ 1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
BMK
2-dehydro-3-deoxy-D-gluconate + NADP+ <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H+ 1.1.1.126 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
–
M
3-dehydro-L-gulonate + NADP+ <=> (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NADPH + H+ 1.1.1.130 3-dehydro-L-gulonate 2-dehydrogenase
–
K
NADP+ + D-mannonate <=> D-mannuronic_acid + NADPH + H+ 1.1.1.131 mannuronate reductase
–
dTDP-L-rhamnose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ 1.1.1.133 dTDP-4-dehydrorhamnose reductase
–
BMK
GDP-6-deoxy-D-talose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ 1.1.1.135 GDP-6-deoxy-D-talose 4-dehydrogenase
1.1.1.187 GDP-4-dehydro-D-rhamnose reductase
–
–
MK
D-ribitol_5-phosphate + NADP+ <=> D-ribulose_5-phosphate + NADPH + H+ 1.1.1.137 ribitol-5-phosphate 2-dehydrogenase
1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+)
–
–
MK
pinitol + NADP+ <=> 5D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADPH + H+ 1.1.1.142 D-pinitol dehydrogenase
–
M
an_11beta-hydroxysteroid + NADP+ <=> an_11-oxosteroid + NADPH + H+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
NADP+ + 16alpha-hydroxysteroid <=> NADPH + a_16-oxosteroid + H+ 1.1.1.147 16alpha-hydroxysteroid dehydrogenase
–
NADP+ + 17alpha-estradiol <=> NADPH + estrone + H+ 1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
K
17alpha,20alpha-dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-hydroxyprogesterone + NADPH + H+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
–
K
pregnan-21-ol + NADP+ <=> pregnan-21-al + NADPH + H+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
dihydrobiopterin + NADP+ <=> sepiapterin + NADPH + H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
–
–
K
(S)-ureidoglycolate + NADP+ <=> Oxalureate + NADPH + H+ 1.1.1.154 ureidoglycolate dehydrogenase
–
MK
NADP+ + glycerol <=> H+ + dihydroxyacetone + NADPH 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.10 L-xylulose reductase
1.1.1.142 D-pinitol dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.72 glycerol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
MK
(S)-3-hydroxybutyryl-CoA + NADP+ <=> acetoacetyl-CoA + NADPH + H+ 1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
–
–
K
NADP+ + UDP-N-acetylmuramate <=> H+ + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine 1.3.1.98 UDP-N-acetylmuramate dehydrogenase
–
BMK
D-threitol + NADP+ <=> D-erythrulose + NADPH + H+ 1.1.1.162 erythrulose reductase
–
(R)-pantoate + NADP+ <=> H+ + ketopantoate + NADPH 1.1.1.169 2-dehydropantoate 2-reductase
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
BMK
3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NADP+ <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
sn-glycerol_3-phosphate + NADP+ <=> D-glyceraldehyde_3-phosphate + NADPH + H+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.177 glycerol-3-phosphate 1-dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
B
D-xylose + NADP+ <=> D-xylono-1,5-lactone + NADPH + H+ 1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.B35
–
–
–
–
–
–
BMK
geraniol + NADP+ <=> citral + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.216 farnesol dehydrogenase (NADP+)
1.1.1.324 8-hydroxygeraniol dehydrogenase
1.1.1.90 aryl-alcohol dehydrogenase
–
–
–
–
–
–
MK
an_L-glycol + NADP+ <=> A_2-hydroxycarbonyl_compound + NADPH + H+ 1.1.1.185 L-glycol dehydrogenase
–
dTDP-galactose + H2O + NADP+ <=> dTDP-D-galacturonate + NADPH + H+ 1.1.1.186 dTDP-galactose 6-dehydrogenase
–
tryptophol + NADP+ <=> H+ + NADPH + Indole-3-acetaldehyde 1.1.1
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
–
BMK
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+ <=> 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH + H+ 1.1.1.193 5-amino-6-(5-phosphoribosylamino)uracil reductase
–
BMK
an_alcohol + NADP+ <=> an_aldehyde + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.263 1,5-anhydro-D-fructose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.4 (R,R)-butanediol dehydrogenase
1.1.1.61 4-hydroxybutyrate dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.80 isopropanol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
K
L-gulono-1,4-lactone + NADP+ <=> D-glucuronolactone + NADPH + H+ 1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.20 glucuronolactone reductase
1.1.1.21 aldose reductase
–
–
–
–
K
a_7beta-hydroxysteroid + NADP+ <=> a_7-oxosteroid + NADPH + H+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
androsterone + NADP+ <=> 5alpha-androstane-3,17-dione + NADPH + H+ 1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
MK
alditol + NADP+ <=> aldose + NADPH + H+ 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.10 L-xylulose reductase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.307 D-xylose reductase
1.1.1.365 D-galacturonate reductase
1.1.1.372 D/L-glyceraldehyde reductase
1.1.1.6 glycerol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
BMK
5alpha-Androstane-3beta,17beta-diol + NADP+ <=> 5alpha-dihydrotestosterone + NADPH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
–
–
–
–
M
D-gluconate + NADP+ <=> 2-dehydro-D-gluconate + NADPH + H+ 1.1.1.215 gluconate 2-dehydrogenase
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
1.1.1.43 phosphogluconate 2-dehydrogenase
–
–
–
MK
NADP+ + benzyl_(2R,3S)-2-methyl-3-hydroxy-butanoate <=> H+ + NADPH + benzyl_2-methyl-3-oxobutanoate 1.1.1.217 benzyl-2-methyl-hydroxybutyrate dehydrogenase
1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
–
–
NADP+ + morphine <=> NADPH + morphinone + H+ 1.1.1.218 morphine 6-dehydrogenase
1.1.1.247 codeinone reductase (NADPH)
–
–
MK
(R)-3-(4-hydroxyphenyl)lactate + NADP+ <=> 4-hydroxyphenylpyruvate + NADPH + H+ 1.1.1.110 aromatic 2-oxoacid reductase
1.1.1.237 hydroxyphenylpyruvate reductase
–
–
MK
NADP+ + Chlordecone_alcohol <=> H+ + Chlordecone + NADPH 1.1.1.225 chlordecone reductase
–
3alpha-Hydroxyglycyrrhetic_acid + NADP+ <=> 3,11-dioxoolean-12-en-30-oic_acid + NADPH + H+ 1.1.1.230 3alpha-hydroxyglycyrrhetinate dehydrogenase
–
NADP+ + (15S)-hydroxyeicosatetraenoic_acid <=> NADPH + 15-Oxo-5,8,11-cis-13-trans-eicosatetraenoate + H+ 1.1.1.232 15-hydroxyicosatetraenoate dehydrogenase
–
BK
NADP+ + (2S)-Flavan-4-ol <=> H+ + NADPH + (2S)-flavanone 1.1.1.234 flavanone 4-reductase
–
coformycin + NADP+ <=> 8-Ketocoformycin + NADPH + H+ 1.1.1.235 8-oxocoformycin reductase
–
3alpha,7alpha,12beta-trihydroxy-5beta-cholanoate + NADP+ <=> 12-ketochenodeoxycholic_acid + NADPH + H+ 1.1.1.238 12beta-hydroxysteroid dehydrogenase
–
M
(-)-trans-carveol + NADP+ <=> (-)-Carvone + NADPH + H+ 1.1.1.243 carveol dehydrogenase
1.3.1.102 2-alkenal reductase (NADP+)
–
–
MK
shikimate + NADP+ <=> 3-dehydroshikimate + NADPH + H+ 1.1.1.24 quinate dehydrogenase
1.1.1.25 shikimate dehydrogenase
1.1.1.282 quinate/shikimate dehydrogenase
–
–
–
BMK
2-C-methyl-D-erythritol_4-phosphate + NADP+ <=> 1-deoxy-D-xylulose_5-phosphate + NADPH + H+ 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase
–
BMK
a_3beta-hydroxysteroid + NADP+ <=> 3-keto_steroid + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
NADP+ + CoA + (R)-mevalonate <=> H+ + NADPH + (S)-3-hydroxy-3-methylglutaryl-CoA 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
1.1.1.88 hydroxymethylglutaryl-CoA reductase
1.1.1.B38
–
–
–
BMK
(S)-malate + NADP+ <=> pyruvate + CO2 + NADPH 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.39 malate dehydrogenase (decarboxylating)
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1.1.1.85 3-isopropylmalate dehydrogenase
–
–
–
–
BMK
isocitrate + NADP+ <=> 2-oxoglutarate + CO2 + NADPH 1.1.1.286 isocitrate---homoisocitrate dehydrogenase
1.1.1.41 isocitrate dehydrogenase (NAD+)
1.1.1.42 isocitrate dehydrogenase (NADP+)
–
–
–
BMK
6-phosphogluconate + NADP+ <=> 6-phospho-2-dehydro-D-gluconate + NADPH + H+ 1.1.1.43 phosphogluconate 2-dehydrogenase
–
MK
6-phosphogluconate + NADP+ <=> D-ribulose_5-phosphate + CO2 + NADPH 1.1.1.351 phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
–
–
BMK
D-glucose_6-phosphate + NADP+ <=> 6-phospho-D-glucono-1,5-lactone + NADPH + H+ 1.1.1.363 glucose-6-phosphate dehydrogenase [NAD(P)+]
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
–
–
BM
testosterone + NADP+ <=> 4-androstene-3,17-dione + NADPH + H+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
–
BMK
allyl_alcohol + NADP+ <=> acrolein + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.54 allyl-alcohol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
M
D-glycerate + NADP+ <=> tartronate_semialdehyde + NADPH + H+ 1.1.1.60 2-hydroxy-3-oxopropionate reductase
–
BMK
17beta-estradiol + NADP+ <=> estrone + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
–
–
–
MK
NADP+ + pyridoxine <=> H+ + NADPH + pyridoxal 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.65 pyridoxine 4-dehydrogenase
–
–
MK
glycolate + NADP+ <=> glyoxylate + NADPH + H+ 1.1.1.21 aldose reductase
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.237 hydroxyphenylpyruvate reductase
1.1.1.26 glyoxylate reductase
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.1.1.92 oxaloglycolate reductase (decarboxylating)
–
–
–
–
–
–
–
BK
2-propanol + NADP+ <=> acetone + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.4 (R,R)-butanediol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.80 isopropanol dehydrogenase (NADP+)
1.1.1.B4
–
–
–
–
–
–
–
–
BMK
D-glycerate + NADP+ <=> Hydroxypyruvate + NADPH + H+ 1.1.1
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.27 L-lactate dehydrogenase
1.1.1.29 glycerate dehydrogenase
1.1.1.60 2-hydroxy-3-oxopropionate reductase
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.1.1.86 ketol-acid reductoisomerase (NADP+)
1.1.1.92 oxaloglycolate reductase (decarboxylating)
–
–
–
–
–
–
–
–
–
BMK
(S)-malate + NADP+ <=> H+ + NADPH + oxaloacetate 1.1.1.299 malate dehydrogenase [NAD(P)+]
1.1.1.37 malate dehydrogenase
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.1.1.82 malate dehydrogenase (NADP+)
–
–
–
–
–
–
BMK
NADP+ + D-glycerate + CO2 <=> NADPH + Oxaloglycolate + H+ 1.1.1.92 oxaloglycolate reductase (decarboxylating)
–
K
3-Hydroxybenzyl_alcohol + NADP+ <=> 3-Hydroxybenzaldehyde + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
K
succinate_semialdehyde + NADP+ + H2O <=> NADPH + succinate + H+ 1.1.1.21 aldose reductase
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
–
–
–
BMK
malonate_semialdehyde + CoA + NADP+ <=> acetyl-CoA + CO2 + NADPH 1.2.1
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
–
–
MK
2,5-dioxopentanoate + H2O + NADP+ <=> 2-oxoglutarate + NADPH + H+ 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
–
–
–
–
BMK
AMP + diphosphate + NADP+ + benzaldehyde <=> ATP + NADPH + aromatic_carboxylate + H+ 1.2.1.30 carboxylate reductase (NADP+)
–
(S)-2-amino-6-oxohexanoate + NADP+ + H2O <=> L-2-aminoadipate + NADPH + H+ 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
–
BMK
formate + NADP+ <=> CO2 + NADPH 1.17.1.10 formate dehydrogenase (NADP+)
1.17.1.9 formate dehydrogenase
–
–
BMK
cinnamaldehyde + CoA + NADP+ <=> cinnamoyl-CoA + NADPH + H+ 1.2.1.44 cinnamoyl-CoA reductase
–
K
4-carboxy-2-hydroxy-cis,cis-muconate_6-semialdehyde + NADP+ <=> 2-Pyrone-4,6-dicarboxylate + NADPH + H+ 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
–
MK
2-Oxoaldehydes + H2O + NADP+ <=> a_2-oxo_carboxylate + NADPH + H+ 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
pyruvate + CoA + NADP+ <=> acetyl-CoA + CO2 + NADPH 1.2.1.51 pyruvate dehydrogenase (NADP+)
–
BM
2-oxoglutarate + CoA + NADP+ <=> succinyl-CoA + CO2 + NADPH 1.2.1.52 oxoglutarate dehydrogenase (NADP+)
–
6-oxohexanoate + H2O + NADP+ <=> H+ + adipate + NADPH 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.63 6-oxohexanoate dehydrogenase
–
–
BMK
coniferyl_aldehyde + NADP+ + H2O <=> ferulic_acid + NADPH + H+ 1.2.1.68 coniferyl-aldehyde dehydrogenase
–
MK
benzaldehyde + H2O + NADP+ <=> benzoate + NADPH + H+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.28 benzaldehyde dehydrogenase (NAD+)
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
MK
D-glyceraldehyde_3-phosphate + NADP+ + H2O <=> H+ + 3-phospho-D-glycerate + NADPH 1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+)
1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
1.2.1.90 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]
–
–
–
MK
dihydrophloroglucinol + NADP+ <=> H+ + phloroglucinol + NADPH 1.3.1.57 phloroglucinol reductase
–
BMK
4-chlorobenzoyl-CoA + Cl- + NADP+ <=> 2,4-dichlorobenzoyl-CoA + NADPH 1.21.1.2 2,4-dichlorobenzoyl-CoA reductase
–
K
NADP+ + cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate <=> CO2 + NADPH + 4-methylcatechol 1.3.1.67 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
–
K
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ 1.3.1.70 Delta14-sterol reductase
–
BMK
5alpha-Cholest-7-en-3beta-ol + NADP+ <=> 5alpha-cholesta-7,24-dien-3beta-ol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
BMK
oxidized_hemoprotein + NADPH + H+ <=> oxidized_hemoprotein + NADP+ 1.6.2.4 NADPH---hemoprotein reductase
–
mycothiol + NADP+ <=> mycothione + NADPH + H+ 1.8.1.15 mycothione reductase
–
M
NADP+ + acetoacetate + coenzyme_M <=> 2-oxopropyl-CoM + NADPH + CO2 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)
–
M
4-hydroxyphenylacetate + O2 + NADPH + H+ <=> homogentisate + H2O + NADP+ 1.14.13.18 4-hydroxyphenylacetate 1-monooxygenase
–
K
(R)-pantolactone + NADP+ <=> ketopantoyl_lactone + NADPH + H+ 1.1.1.168 2-dehydropantolactone reductase (Re-specific)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.214 2-dehydropantolactone reductase (Si-specific)
1.1.1.358 2-dehydropantolactone reductase
1.1.1.B51
–
–
–
–
–
M
cholic_acid + NADP+ <=> H+ + NADPH + 12-ketochenodeoxycholic_acid 1.1.1.176 12alpha-hydroxysteroid dehydrogenase
–
M
cinnamyl_alcohol + NADP+ <=> cinnamaldehyde + NADPH + H+ 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.54 allyl-alcohol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.90 aryl-alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
Prostaglandin_D2 + NADP+ <=> (5Z,13E)-9alpha-Hydroxy-11,15-dioxoprosta-5,13-dienoate + NADPH + H+ 1.1.1.189 prostaglandin-E2 9-reductase
1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
–
–
prostaglandin_E1 + NADP+ <=> 15-dehydro-prostaglandin_E1 + NADPH + H+ 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
–
D-sorbitol_6-phosphate + NADP+ <=> D-glucose_6-phosphate + NADPH + H+ 1.1.1.200 aldose-6-phosphate reductase (NADPH)
–
M
Tropine + NADP+ <=> tropinone + NADPH + H+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
1.1.1.334 methylecgonone reductase
–
–
–
MK
NADP+ + (-)-menthol <=> H+ + (-)-menthone + NADPH 1.1.1.207 (-)-menthol dehydrogenase
–
MK
NADP+ + (+)-neomenthol <=> H+ + NADPH + (-)-menthone 1.1.1.208 (+)-neomenthol dehydrogenase
–
MK
(2E,6E)-farnesol + NADP+ <=> (2E,6E)-farnesal + NADPH + H+ 1.1.1.21 aldose reductase
1.1.1.216 farnesol dehydrogenase (NADP+)
–
–
MK
(2R,3S,4S)-leucoanthocyanidin + NADP+ <=> (2R,3R)-dihydroflavonol + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
NADP+ + D-mannitol_1-phosphate <=> D-mannose_6-phosphate + NADPH + H+ 1.1.1.224 mannose-6-phosphate 6-reductase
–
M
NADP+ + prostaglandin_I2 <=> H+ + NADPH + (5Z,13E)-6,9alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
–
–
N,N-Dimethylaniline + O2 + NADPH + H+ <=> N,N-Dimethylaniline_N-oxide + H2O + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
L-kynurenine + O2 + NADPH + H+ <=> L-3-hydroxykynurenine + H2O + NADP+ 1.14.13.9 kynurenine 3-monooxygenase
–
BMK
NADP+ + H2O + malonate_semialdehyde <=> malonate + NADPH + H+ 1.2.1.15 malonate-semialdehyde dehydrogenase
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
–
BK
an_aldehyde + NADP+ + H2O <=> a_carboxylate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
M
5,6-dihydrouracil + NADP+ <=> Uracil + NADPH + H+ 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
–
BMK
trans-benzene_dihydrodiol + NADP+ <=> catechol + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
cholesterol + NADP+ <=> 7-dehydrocholesterol + NADPH + H+ 1.3.1.21 7-dehydrocholesterol reductase
–
BMK
GDP-6-deoxy-D-mannose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ 1.1.1.187 GDP-4-dehydro-D-rhamnose reductase
1.1.1.281 GDP-4-dehydro-6-deoxy-D-mannose reductase
–
–
MK
dTDP-6-deoxy-beta-L-talose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ 1.1.1.134 dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+)
1.1.1.344 dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+]
–
–
K
(+-)-5-[(tert-butylamino)-2''-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+ <=> (+-)-5-[(tert-butylamino)-2''-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH + H+ 1.1.1.160 dihydrobunolol dehydrogenase
–
prostaglandin_F2alpha + NADP+ <=> Prostaglandin_D2 + NADPH + H+ 1.1.1.188 prostaglandin-F synthase
–
prostaglandin_F2alpha + NADP+ <=> NADPH + prostaglandin_E2 + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.189 prostaglandin-E2 9-reductase
–
–
BK
coniferyl_alcohol + NADP+ <=> coniferyl_aldehyde + NADPH + H+ 1.1.1.194 coniferyl-alcohol dehydrogenase
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.90 aryl-alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
BMK
NADP+ + Diethyl_(2R,3R)-2-methyl-3-hydroxysuccinate <=> H+ + NADPH + Diethyl_2-methyl-3-oxosuccinate 1.1.1.229 diethyl 2-methyl-3-oxosuccinate reductase
–
GDP-L-fucose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ 1.1.1.271 GDP-L-fucose synthase
–
K
(R)-2-hydroxyacid + NADP+ <=> a_2-oxo_carboxylate + NADPH + H+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
–
D-gluconate + NADP+ <=> 5-Dehydro-D-gluconate + NADPH + H+ 1.1.1
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.69 gluconate 5-dehydrogenase
–
–
–
BM
benzyl_alcohol + NADP+ <=> benzaldehyde + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.90 aryl-alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
4-hydroxybenzoate + NADPH + O2 + H+ <=> 3,4-dihydroxybenzoate + NADP+ + H2O 1.14.13.2 4-hydroxybenzoate 3-monooxygenase
1.14.13.33 4-hydroxybenzoate 3-monooxygenase [NAD(P)H]
–
–
BMK
L-aspartate_4-semialdehyde + phosphate + NADP+ <=> L-4-aspartyl_phosphate + NADPH + H+ 1.2.1.11 aspartate-semialdehyde dehydrogenase
–
BMK
glyoxylate + CoA + NADP+ <=> oxalyl-CoA + NADPH + H+ 1.2.1.17 glyoxylate dehydrogenase (acylating)
–
MK
N-acetyl-L-glutamate_5-semialdehyde + NADP+ + phosphate <=> H+ + N-acetyl-L-glutamyl_5-phosphate + NADPH 1.2.1.38 N-acetyl-gamma-glutamyl-phosphate reductase
–
BMK
L-glutamate_5-semialdehyde + phosphate + NADP+ <=> L-5-glutamyl_phosphate + NADPH + H+ 1.2.1.41 glutamate-5-semialdehyde dehydrogenase
–
BMK
prephenate + NADP+ <=> 4-hydroxyphenylpyruvate + CO2 + NADPH 1.3.1.12 prephenate dehydrogenase
1.3.1.13 prephenate dehydrogenase (NADP+)
1.3.1.78 arogenate dehydrogenase (NADP+)
1.3.1.79 arogenate dehydrogenase [NAD(P)+]
–
–
–
–
K
L-dihydroorotate + NADP+ <=> H+ + Orotate + NADPH 1.3.1.15 dihydroorotate dehydrogenase (NADP+)
–
3-nitropropionate + NADP+ <=> H+ + 3-Nitroacrylate + NADPH 1.3.1.16 beta-nitroacrylate reductase
–
3-methyloxindole + NADP+ <=> 3-methyleneoxindole + NADPH + H+ 1.3.1.17 3-methyleneoxindole reductase
–
5beta-cholestan-3-one + NADP+ <=> H+ + cholest-4-en-3-one + NADPH 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADP+ + H2O <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+ 1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase
–
BMK
hexadecanal + NADP+ <=> 2-trans-hexadecenal + NADPH + H+ 1.3.1.27 2-hexadecenal reductase
–
BM
17alpha,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ <=> H+ + cortisone + NADPH 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
K
3-oxoadipate + NADP+ <=> maleylacetate + NADPH + H+ 1.3.1.32 maleylacetate reductase
–
BMK
trans-2-enoyl-CoA + NADP+ <=> trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
–
acyl-CoA + NADP+ <=> cis-2,3-dehydroacyl-CoA + NADPH + H+ 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH)
–
acyl-CoA + NADP+ <=> trans-2-enoyl-CoA + NADPH + H+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.44 trans-2-enoyl-CoA reductase (NAD+)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
–
K
2,6-Dioxo-6-phenylhexanoate + NADP+ <=> 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + NADPH + H+ 1.3.1.40 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
–
NADP+ + 3-oxo-2((2Z)-pentenyl)-cyclopentane-1-octanoic_acid <=> H+ + NADPH + 12-oxo-phytodienoic_acid 1.3.1.42 12-oxophytodienoate reductase
–
MK
vestitone + NADP+ <=> 2'-hydroxyformononetin + NADPH + H+ 1.3.1.45 2'-hydroxyisoflavone reductase
1.3.1.51 2'-hydroxydaidzein reductase
–
–
MK
NADP+ + dihydrobiochanin-A <=> NADPH + Biochanin_A + H+ 1.3.1.46 biochanin-A reductase
–
K
NADP+ + 1,2-dihydrosantonin <=> NADPH + alpha-santonin + H+ 1.3.1.47 alpha-santonin 1,2-reductase
–
23,24-dihydrocucurbitacin_B + NADP+ <=> cucurbitacin_B + NADPH + H+ 1.3.1.5 cucurbitacin Delta23-reductase
–
ergosterol + NADP+ <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADPH + H+ 1.3.1.71 Delta24(241)-sterol reductase
1.3.1.72 Delta24-sterol reductase
–
–
MK
2,4-Diaminopentanoate + H2O + NADP+ <=> (2R)-2-amino-4-oxopentanoate + NH3 + NADPH + H+ 1.4.1.12 2,4-diaminopentanoate dehydrogenase
–
BMK
L-glutamate + NADP+ <=> H+ + L-glutamine + 2-oxoglutarate + NADPH 1.4.1.13 glutamate synthase (NADPH)
1.4.1.B5
–
–
BMK
meso-2,6-diaminoheptanedioate + NADP+ + H2O <=> L-2-amino-6-oxopimelate + NH3 + NADPH + H+ 1.4.1.16 diaminopimelate dehydrogenase
–
BMK
N-Methyl-L-alanine + H2O + NADP+ <=> H+ + methylamine + pyruvate + NADPH 1.4.1.17 N-methylalanine dehydrogenase
1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
–
L-tryptophan + H2O + NADP+ <=> 3-Indole-2-oxopropanoate + NH3 + NADPH + H+ 1.4.1.19 tryptophan dehydrogenase
–
NADP+ + H2O + L-glutamate <=> NADPH + 2-oxoglutarate + NH3 + H+ 1.4.1.13 glutamate synthase (NADPH)
1.4.1.2 glutamate dehydrogenase
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
–
–
–
–
BMK
L-valine + H2O + NADP+ <=> 2-oxoisovalerate + NH3 + NADPH + H+ 1.4.1.23 valine dehydrogenase (NAD+)
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
1.4.1.8 valine dehydrogenase (NADP+)
–
–
–
–
L-proline + NADP+ <=> DELTA1-pyrroline-2-carboxylate + NADPH + H+ 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]
1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
1.5.1.25 thiomorpholine-carboxylate dehydrogenase
1.5.1.49 1-pyrroline-2-carboxylate reductase [NAD(P)H]
–
–
–
–
BMK
H2O + NADP+ + D-lysopine <=> H+ + NADPH + pyruvate + L-lysine 1.5.1.11 D-octopine dehydrogenase
1.5.1.16 D-lysopine dehydrogenase
–
–
K
L-proline + NADP+ <=> L-pyrroline-5-carboxylate + NADPH + H+ 1.5.1.2 pyrroline-5-carboxylate reductase
–
BMK
L-pipecolic_acid + NADP+ <=> DELTA1-piperideine-2-carboxylate + NADPH + H+ 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]
1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
1.5.1.25 thiomorpholine-carboxylate dehydrogenase
1.5.1.49 1-pyrroline-2-carboxylate reductase [NAD(P)H]
–
–
–
–
MK
H2O + NADP+ + N5-(L-1-carboxyethyl)-L-ornithine <=> H+ + NADPH + pyruvate + L-ornithine 1.5.1.24 N5-(carboxyethyl)ornithine synthase
–
FMNH2 + NADP+ <=> FMN + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
1.5.1
1.5.1.30 flavin reductase (NADPH)
1.5.1.36 flavin reductase (NADH)
1.5.1.38 FMN reductase (NADPH)
1.5.1.39 FMN reductase [NAD(P)H]
1.5.1.41 riboflavin reductase [NAD(P)H]
1.5.1.42 FMN reductase (NADH)
1.5.1.45 FAD reductase [NAD(P)H]
–
–
–
–
–
–
–
–
–
BMK
tetrahydrofolate + NADP+ <=> 7,8-dihydrofolate + NADPH + H+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
1.5.1.34 6,7-dihydropteridine reductase
1.5.1.50 dihydromonapterin reductase
–
–
–
–
BMK
reduced_riboflavin + NADP+ <=> H+ + riboflavin + NADPH 1.5.1.30 flavin reductase (NADPH)
1.5.1.38 FMN reductase (NADPH)
1.5.1.41 riboflavin reductase [NAD(P)H]
–
–
–
BK
5,10-methylenetetrahydrofolate + NADP+ <=> 5,10-methenyltetrahydrofolate + NADPH 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
–
–
BMK
saccharopine + H2O + NADP+ <=> L-lysine + 2-oxoglutarate + NADPH + H+ 1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming)
–
BMK
NAD+ + NADPH <=> NADH + NADP+ 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)
1.6.1.3 NAD(P)+ transhydrogenase
7.1.1.1 proton-translocating NAD(P)+ transhydrogenase
–
–
–
–
BMK
acceptor + NADPH + H+ <=> reduced_acceptor + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.99.1 NADPH dehydrogenase
–
–
–
NH3 + NADP+ + H2O <=> nitrite + NADPH + H+ 1.7.1.4 nitrite reductase [NAD(P)H]
1.7.7.1 ferredoxin---nitrite reductase
1.8.1.2 assimilatory sulfite reductase (NADPH)
–
–
–
MK
4-(hydroxyamino)quinoline_N-oxide + NADP+ + H2O <=> 4-Nitroquinoline_N-oxide + NADPH + H+ 1.7.1.9 nitroquinoline-N-oxide reductase
–
gamma-Glu-L-Cys + NADP+ <=> H+ + bis-gamma-glutamylcystine + NADPH 1.8.1.13 bis-gamma-glutamylcystine reductase
–
BK
Sulfide + NADP+ + H2O <=> sulfite + NADPH + H+ 1.8.1.2 assimilatory sulfite reductase (NADPH)
–
BMK
CoA + NADP+ <=> CoA-disulfide + NADPH + H+ 1.8.1.10 CoA-glutathione reductase
1.8.1.14 CoA-disulfide reductase
1.8.4.2 protein-disulfide reductase (glutathione)
–
–
–
B
IMP + NH3 + NADP+ <=> GMP + NADPH + H+ 1.7.1.7 GMP reductase
–
BK
N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ <=> 4-(dimethylamino)azobenzene + NADPH + H+ 1.7.1.6 azobenzene reductase
–
H2O + NADP+ + 2-acetylaminofluorene <=> NADPH + N-Hydroxy-2-acetylaminofluorene + H+ 1.7.1.12 N-hydroxy-2-acetamidofluorene reductase
–
4-(dimethylamino)azobenzene + NADP+ + H2O <=> 4-(dimethylamino)phenylazoxybenzene + NADPH + H+ 1.7.1.11 4-(dimethylamino)phenylazoxybenzene reductase
–
NADPH + ferricytochrome_b5 <=> NADP+ + ferricytochrome_b5 + H+ 1.18.1.2 ferredoxin---NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
1.6.2.2 cytochrome-b5 reductase
1.6.2.4 NADPH---hemoprotein reductase
1.6.2.5 NADPH---cytochrome-c2 reductase
1.6.2.6 leghemoglobin reductase
–
–
–
–
–
–
glutathione + NADP+ <=> GSSG + NADPH + H+ 1.8.1.7 glutathione-disulfide reductase
1.8.1.9 thioredoxin-disulfide reductase
1.8.1.B1
1.8.4.2 protein-disulfide reductase (glutathione)
–
–
–
–
BMK
trypanothione + NADP+ <=> trypanothione_disulfide + NADPH + H+ 1.8.1.12 trypanothione-disulfide reductase
–
BK
glutathione + CoA + NADP+ <=> H+ + CoA-glutathione + NADPH 1.8.1.10 CoA-glutathione reductase
1.8.1.14 CoA-disulfide reductase
1.8.4.2 protein-disulfide reductase (glutathione)
–
–
–
Questin + O2 + NADPH <=> demethylsulochrin + NADP+ 1.14.13.43 questin monooxygenase
–
M
taxifolin + O2 + NADPH + H+ <=> 2,3-dihydrogossypetin + H2O + NADP+ 1.14.13.19 taxifolin 8-monooxygenase
–
(+)-trans-Acenaphthene-1,2-diol + NADP+ <=> acenaphthenequinone + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.10.1.1 trans-acenaphthene-1,2-diol dehydrogenase
–
–
1,2-dihydrovomilenine + NADP+ <=> Vomilenine + NADPH + H+ 1.5.1.32 vomilenine reductase
–
MK
saccharopine + NADP+ + H2O <=> H+ + L-glutamate + (S)-2-amino-6-oxohexanoate + NADPH 1.5.1.10 saccharopine dehydrogenase (NADP+, L-glutamate-forming)
–
BMK
NADP+ + bilirubin <=> Biliverdin + NADPH + H+ 1.3.1.24 biliverdin reductase
–
BMK
reduced_rubredoxin + NADP+ + H+ <=> oxidized_rubredoxin + NADPH 1.18.1.1 rubredoxin---NAD+ reductase
1.18.1.4 rubredoxin---NAD(P)+ reductase
–
–
BK
CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADP+ + H2O <=> CDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ 1.17.1.1 CDP-4-dehydro-6-deoxyglucose reductase
–
MK
Hg + NADP+ + H+ <=> Hg2+ + NADPH 1.16.1.1 mercury(II) reductase
–
BM
phenol + O2 + NADPH + H+ <=> catechol + H2O + NADP+ 1.14.13.7 phenol 2-monooxygenase (NADPH)
1.14.14.20 phenol 2-monooxygenase (FADH2)
–
–
BMK
6-Oxocineole + O2 + NADPH + H+ <=> 1,6,6-Trimethyl-2,7-dioxa(3,2,2)bicyclononan-3-one + H2O + NADP+ 1.14.13.51 6-oxocineole dehydrogenase
–
MK
Pentachlorophenol + O2 + NADPH + H+ <=> tetrafluoro-1,4-benzoquinone + Cl- + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
MK
2-aminobenzoyl-CoA + O2 + NADPH + H+ <=> 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + NADP+ 1.14.13.40 anthraniloyl-CoA monooxygenase
–
MK
anhydrotetracycline + O2 + NADPH + H+ <=> 5a,11a-dehydrotetracycline + H2O + NADP+ 1.14.13.38 anhydrotetracycline 6-monooxygenase
–
MK
H+ + anthranilate + O2 + NADPH <=> NH3 + NADP+ + 2,3-Dihydroxybenzoate 1.14.13.35 anthranilate 3-monooxygenase (deaminating)
–
K
leukotriene_E4 + O2 + NADPH + H+ <=> 20-hydroxy-leukotriene_E4 + H2O + NADP+ 1.14.13.34 leukotriene-E4 20-monooxygenase
–
K
2-Nitrophenol + O2 + NADPH + H+ <=> catechol + nitrite + H2O + NADP+ 1.14.13.31 2-nitrophenol 2-monooxygenase
–
M
4-Aminobenzoic_acid + O2 + NADPH + H+ <=> 4-Aminophenol + CO2 + H2O + NADP+ 1.14.13.27 4-aminobenzoate 1-monooxygenase
–
K
methane + NADPH + O2 + H+ <=> methanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
1.14.15.3 alkane 1-monooxygenase
–
–
M
3-hydroxybenzoate + O2 + NADPH + H+ <=> 3,4-dihydroxybenzoate + H2O + NADP+ 1.14.13.2 4-hydroxybenzoate 3-monooxygenase
1.14.13.23 3-hydroxybenzoate 4-monooxygenase
–
–
MK
cyclohexanone + NADPH + H+ + O2 <=> epsilon-caprolactone + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
–
BMK
2,4-Dichlorophenol + O2 + NADPH + H+ <=> 3,5-dichlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
–
MK
Cyclopentanone + O2 + NADPH + H+ <=> delta-valerolactone + H2O + NADP+ 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
H+ + Cinnamic_acid + O2 + NADPH <=> H2O + NADP+ + coumaric_acid 1.14.13.14 trans-cinnamate 2-monooxygenase
1.14.14.91 trans-cinnamate 4-monooxygenase
–
–
MK
nicotinate + O2 + NADPH <=> 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate + NADP+ 1.14.13.241 5-pyridoxate monooxygenase
–
K
anthranilate + O2 + NADPH + H+ <=> catechol + CO2 + NH3 + NADP+ 1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
–
MK
NADP+ + H2 <=> NADPH + H+ 1.12.1.2 hydrogen dehydrogenase
1.12.1.3 hydrogen dehydrogenase (NADP+)
1.12.1.5 hydrogen dehydrogenase [NAD(P)+]
–
–
–
BM
H+ + H2O2 + NADPH <=> H2O + NADP+ 1.11.1.1 NADH peroxidase
1.11.1.11 L-ascorbate peroxidase
1.11.1.2 NADPH peroxidase
1.11.1.24 thioredoxin-dependent peroxiredoxin
1.11.1.27 glutathione-dependent peroxiredoxin
1.11.1.5 cytochrome-c peroxidase
1.11.1.6 catalase
1.11.1.7 peroxidase
–
–
–
–
–
–
–
–
10-deoxysarpagine + NADP+ <=> gardneral + NADPH + H+ 1.1.1.273 vellosimine dehydrogenase
–
MK
2-dehydro-D-gluconate + NADP+ <=> H+ + NADPH + 2,5-didehydro-D-gluconate 1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
BM
(R)-canadine + NADP+ <=> Berberine + NADPH + H+ 1.5.1.31 berberine reductase
–
K
NADP+ + 1,4-Thiomorpholine_3-carboxylic_acid <=> NADPH + S-Aminoethylcysteine_ketimine + H+ 1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
17-O-acetylnorajmaline + NADP+ <=> 1,2-dihydrovomilenine + NADPH + H+ 1.3.1.73 1,2-dihydrovomilenine reductase
–
MK
NADP+ + dihydrozeatin <=> H+ + trans-zeatin + NADPH 1.3.1.69 zeatin reductase
–
K
tetrahydrobiopterin + NADP+ <=> biopterin + NADPH + H+ 1.5.1.33 pteridine reductase
–
K
tetrahydropteridine + NADP+ <=> dihydropteridine + NADPH + H+ 1.5.1.34 6,7-dihydropteridine reductase
–
M
S-adenosyl-L-methionine + palmatine + NADPH <=> S-adenosyl-L-homocysteine + corydaline + NADP+ 2.1.1.147 corydaline synthase
–
K
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 6-Methylsalicylate + CoA + CO2 + NADP+ + H2O 2.3.1.165 6-methylsalicylic-acid synthase
–
MK
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> fatty_acid + CoA + CO2 + NADP+ 2.3.1.38 [acyl-carrier-protein] S-acetyltransferase
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
K
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> stearoyl-CoA + CoA + CO2 + NADP+ 2.3.1.86 fatty-acyl-CoA synthase system
–
K
propionyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> 6-Deoxyerythronolide_b + CoA + CO2 + H2O + NADP+ 2.3.1.94 6-deoxyerythronolide-B synthase
–
MK
(2E,6E)-farnesyl_diphosphate + NADPH + H+ <=> squalene + diphosphate + NADP+ 2.5.1.148 lycopaoctaene synthase
2.5.1.21 squalene synthase
–
–
K
magnesium_protoporphyrin_monomethyl_ester + NADPH + H+ + O2 <=> divinyl_protochlorophyllide_a + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
K
catechin + NADP+ + H2O <=> Leucocyanidin + NADPH + H+ 1.17.1.3 leucoanthocyanidin reductase
–
MK
5beta-Pregnan-3beta-ol-20-one + NADP+ <=> H+ + 5beta-pregnane-3,20-dione + NADPH 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.277 3beta-hydroxy-5beta-steroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
–
–
–
–
M
an_n-alkanal + NADP+ <=> alk-2-enal + NADPH + H+ 1.3.1.102 2-alkenal reductase (NADP+)
1.3.1.74 2-alkenal reductase [NAD(P)+]
–
–
NADPH + H+ + O2 <=> NADP+ + H2O2 1.6.3.1 NAD(P)H oxidase (H2O2-forming)
1.6.3.3 NADH oxidase (H2O2-forming)
–
–
L-serine + NADP+ <=> aminoacetaldehyde + NADPH + CO2 1.1.1.276 serine 3-dehydrogenase (NADP+)
–
5alpha-pregnane-3beta-ol-20-one + NADP+ <=> H+ + 5alpha-dihydroprogesterone + NADPH 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.278 3beta-hydroxy-5alpha-steroid dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
–
–
–
–
–
–
–
MK
NADP+ + ethyl_(R)-3-hydroxyhexanoate <=> H+ + NADPH + ethyl_3-oxohexanoate 1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase
–
NADP+ + ethyl_(S)-3-hydroxyhexanoate <=> H+ + NADPH + ethyl_3-oxohexanoate 1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
1.1.1.283 methylglyoxal reductase (NADPH)
–
–
(R)-2,3-dihydroxy-3-methylbutanoate + NADP+ <=> (S)-2-Hydroxy-2-methyl-3-oxobutanoate + NADPH + H+ 1.1.1.383 ketol-acid reductoisomerase [NAD(P)+]
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
MK
protochlorophyllide + NADP+ <=> divinyl_protochlorophyllide_a + NADPH + H+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
BK
NAD+ + ATP <=> H+ + NADP+ + ADP 2.7.1.23 NAD+ kinase
–
BMK
nicotinate + H2O + NADP+ <=> 6-Hydroxynicotinate + NADPH + H+ 1.17.1.5 nicotinate dehydrogenase
–
MK
quinate + NADP+ <=> 3-dehydroquinate + NADPH + H+ 1.1.1.24 quinate dehydrogenase
1.1.1.25 shikimate dehydrogenase
1.1.1.282 quinate/shikimate dehydrogenase
–
–
–
MK
4-hydroxyacetophenone + NADPH + O2 + H+ <=> 4-hydroxyphenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
MK
octadecanal + O2 + NADPH + H+ <=> heptadecane + formate + H2O + NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
M
L-aspartate + H2O + NADP+ <=> oxaloacetate + NH3 + NADPH + H+ 1.4.1.2 glutamate dehydrogenase
1.4.1.21 aspartate dehydrogenase
–
–
L-lactaldehyde + NADP+ <=> methylglyoxal + NADPH + H+ 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.78 methylglyoxal reductase (NADH)
1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
BMK
squalene + diphosphate + NADP+ <=> presqualene_diphosphate + NADPH + H+ 1.3.1.96 Botryococcus squalene synthase
1.3.1.97 botryococcene synthase
2.5.1.21 squalene synthase
–
–
–
BMK
senecionine + NADPH + O2 + H+ <=> senecionine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
MK
S-hydroxymethylglutathione + NADP+ <=> S-formylglutathione + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase
–
–
BM
L-arogenate + NADP+ <=> L-tyrosine + CO2 + NADPH 1.3.1.43 arogenate dehydrogenase
1.3.1.78 arogenate dehydrogenase (NADP+)
1.3.1.79 arogenate dehydrogenase [NAD(P)+]
–
–
–
BMK
2,3,5,6-Tetrachlorophenol + NADPH + O2 <=> tetrachlorohydroquinone + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
2,3-cis-flavan-3-ol + NADP+ <=> anthocyanidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
M
H+ + 4-coumaroyl-CoA + malonyl-CoA + NADPH <=> isoliquiritigenin + CoA + CO2 + NADP+ + H2O 2.3.1.170 6'-deoxychalcone synthase
–
MK
2''-deoxymugineate + NADP+ <=> 3''''-deamino-3''''-oxonicotianamine + NADPH + H+ 1.1.1.285 3''-deamino-3''-oxonicotianamine reductase
–
M
D-arabitol + NADP+ <=> D-xylulose + NADPH + H+ 1.1.1.14 L-iditol 2-dehydrogenase
1.1.1.287 D-arabinitol dehydrogenase (NADP+)
–
–
K
D-arabitol + NADP+ <=> D-ribulose + NADPH + H+ 1.1.1.287 D-arabinitol dehydrogenase (NADP+)
–
K
chlorophyllide_a + O2 + NADPH + H+ <=> 7-hydroxychlorophyllide_a + H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
BMK
chlorophyllide_a + O2 + NADPH + H+ <=> chlorophyllide_b + H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
phenylacetone + NADPH + O2 + H+ <=> Benzyl_acetate + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
pre-queuine_1 + NADP+ <=> 7-cyano-7-carbaguanine + NADPH + H+ 1.7.1.13 preQ1 synthase
–
MK
1,5-anhydro-D-mannitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+ 1.1.1.263 1,5-anhydro-D-fructose reductase
1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
–
–
M
3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NADP+ <=> momilactone_A + NADPH + H+ 1.1.1.295 momilactone-A synthase
–
MK
(-)-menthone + NADPH + H+ + O2 <=> (4R,7S)-7-isopropyl-4-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
K
isodihydrocarvone + NADPH + H+ + O2 <=> isoprop(en)ylmethyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
1-hydroxymenth-8-en-2-one + NADPH + H+ + O2 <=> 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
(-)-menthone + NADP+ <=> (R)-pulegone + NADPH + H+ 1.3.1.81 (+)-pulegone reductase
–
MK
(+)-isomenthone + NADP+ <=> (R)-pulegone + NADPH + H+ 1.3.1.81 (+)-pulegone reductase
–
MK
(+)-cis-isopulegone + NADP+ <=> (-)-isopiperitenone + NADPH + H+ 1.3.1.82 (-)-isopiperitenone reductase
–
MK
all-trans-retinol + NADP+ <=> all-trans-retinal + NADPH + H+ 1.1.1
1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.300 NADP-retinol dehydrogenase
1.1.1.315 11-cis-retinol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
–
–
–
–
MK
(+)-epi-isozizaene + O2 + NADPH + H+ <=> (5S)-albaflavenol + H2O + NADP+ 1.14.13.106 epi-isozizaene 5-monooxygenase
–
MK
(5S)-albaflavenol + O2 + NADPH + H+ <=> albaflavenone + H2O + NADP+ 1.14.13.106 epi-isozizaene 5-monooxygenase
–
MK
(+)-epi-isozizaene + O2 + NADPH + H+ <=> (5R)-albaflavenol + H2O + NADP+ 1.14.13.106 epi-isozizaene 5-monooxygenase
–
MK
(5R)-albaflavenol + O2 + NADPH + H+ <=> albaflavenone + H2O + NADP+ 1.14.13.106 epi-isozizaene 5-monooxygenase
–
MK
limonene + NADPH + H+ + O2 <=> 1,2-epoxymenth-8-ene + NADP+ + H2O 1.14.13.107 limonene 1,2-monooxygenase
–
phytyl_diphosphate + NADP+ <=> geranylgeranyl_diphosphate + NADPH + H+ 1.3.1.83 geranylgeranyl diphosphate reductase
–
BK
4-hydroxylamino-2,6-dinitrotoluene + H2O + NADP+ <=> 2,4,6-trinitrotoluene + NADPH + H+ 1
1.7.1
1.7.1.B1
1.7.1.B3
–
–
–
–
K
3-hydroxypropionate + NADP+ <=> malonate_semialdehyde + NADPH + H+ 1.1.1
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.276 serine 3-dehydrogenase (NADP+)
1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)
–
–
–
–
BMK
malonate_semialdehyde + CoA + NADP+ <=> malonyl-CoA + NADPH + H+ 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming)
–
–
BMK
succinate_semialdehyde + NADP+ + CoA <=> succinyl-CoA + NADPH + H+ 1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming)
1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)
–
–
BMK
propionyl-CoA + NADP+ <=> acryloyl-CoA + NADPH + H+ 1.3.1
1.3.1.84 acrylyl-CoA reductase (NADPH)
1.3.1.95 acrylyl-CoA reductase (NADH)
–
–
–
BMK
benzoyl-CoA + NADPH + H+ + O2 <=> 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O 1.14.13.208 benzoyl-CoA 2,3-epoxidase
–
MK
2,5-diamino-6-(1-D-ribitylamino)-4(3H)-pyrimidinone_5'-phosphate + NADP+ <=> 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate + NADPH + H+ 1.1.1.302 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
–
K
xylitol + NADP+ <=> D-xylose + NADPH + H+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.188 prostaglandin-F synthase
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.289 sorbose reductase
1.1.1.307 D-xylose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
MK
L-tyrosine + NADP+ + I- <=> 3-iodo-L-tyrosine + NADPH 1.21.1.1 iodotyrosine deiodinase
–
3-iodo-L-tyrosine + I- + NADP+ <=> 3,5-diiodo-L-tyrosine + NADPH + H+ 1.21.1.1 iodotyrosine deiodinase
–
L-ornithine + O2 + NADPH <=> N5-hydroxy-L-ornithine + H2O + NADP+ 1.14.13.195 L-ornithine N5-monooxygenase (NADPH)
1.14.13.196 L-ornithine N5-monooxygenase [NAD(P)H]
–
–
BM
carbazole + O2 + NADPH + H+ <=> 2''-aminobiphenyl-2,3-diol + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
MK
(2S)-ethylmalonyl-CoA + NADP+ <=> crotonyl-CoA + CO2 + NADPH 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
BMK
butyryl-CoA + NADP+ <=> crotonyl-CoA + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
1.3.1.44 trans-2-enoyl-CoA reductase (NAD+)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
1.3.1.85 crotonyl-CoA carboxylase/reductase
1.3.1.86 crotonyl-CoA reductase
1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
–
–
–
–
–
–
–
–
K
7-methylxanthine + NADPH + O2 + H+ <=> xanthine + NADP+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
–
BMK
isethionate + NADP+ <=> 2-sulfoacetaldehyde + NADPH + H+ 1.1.1.313 sulfoacetaldehyde reductase
–
MK
2-sulfoacetaldehyde + CoA + NADP+ <=> sulfoacetyl-CoA + NADPH + H+ 1.2.1.81 sulfoacetaldehyde dehydrogenase (acylating)
–
M
N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O <=> L-arginine + 2-oxoglutarate + NADPH + H+ 1.5.1.19 D-nopaline dehydrogenase
–
K
N2O + NADP+ + H2O <=> NO + NADPH + H+ 1.7.1.14 nitric oxide reductase [NAD(P)+, nitrous oxide-forming]
1.7.2.5 nitric oxide reductase (cytochrome c)
–
–
K
gamma-glutamyl-gamma-aminobutyraldehyde + NADP+ + H2O <=> 4-(glutamylamino)_butanoate + NADPH + H+ 1.2.1.99 4-(gamma-glutamylamino)butanal dehydrogenase
–
BMK
5,6-dihydrouracil16_in_tRNA + NADP+ <=> uracil16_in_tRNA + NADPH + H+ 1.3.1.88 tRNA-dihydrouridine16/17 synthase [NAD(P)+]
–
5,6-dihydrouracil17_in_tRNA + NADP+ <=> uracil17_in_tRNA + NADPH + H+ 1.3.1.88 tRNA-dihydrouridine16/17 synthase [NAD(P)+]
–
5,6-dihydrouracil20_in_tRNA + NADP+ <=> uracil20_in_tRNA + NADPH + H+ 1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+]
–
5,6-dihydrouracil47_in_tRNA + NADP+ <=> uracil47_in_tRNA + NADPH + H+ 1.3.1.89 tRNA-dihydrouridine47 synthase [NAD(P)+]
–
5,6-dihydrouracil20a_in_tRNA + NADP+ <=> uracil20a_in_tRNA + NADPH + H+ 1.3.1.90 tRNA-dihydrouridine20a/20b synthase [NAD(P)+]
–
5,6-dihydrouracil20b_in_tRNA + NADP+ <=> uracil20b_in_tRNA + NADPH + H+ 1.3.1.90 tRNA-dihydrouridine20a/20b synthase [NAD(P)+]
–
carboxynorspermidine + NADP+ + H2O <=> L-aspartate_4-semialdehyde + 1,3-diaminopropane + NADPH + H+ 1.4.1.B4
1.5.1.43 carboxynorspermidine synthase
–
–
BMK
reduced_coenzyme_F420 + NADP+ <=> coenzyme_F420 + NADPH + H+ 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
–
S-adenosyl-L-methionine + L-tyrosine + NADPH <=> 2-iminoacetate + p-Cresol + 5''-deoxyadenosine + L-methionine + NADP+ + H+ 4.1.99.19 2-iminoacetate synthase
–
BM
progesterone + NADPH + H+ + O2 <=> Testosterone_acetate + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
1.14.99.4 progesterone monooxygenase
–
–
4-androstene-3,17-dione + NADPH + H+ + O2 <=> testololactone + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
1.14.99.12 androst-4-ene-3,17-dione monooxygenase
–
–
17alpha-hydroxyprogesterone + NADPH + O2 <=> 4-androstene-3,17-dione + acetate + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
–
3-oxo-5,6-dehydrosuberyl-CoA_semialdehyde + NADP+ + H2O <=> 3-oxo-5,6-dehydrosuberyl-CoA + NADPH + H+ 1.2.1.91 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase
–
BMK
1-hydroxy-2-naphthoate + NADPH + O2 + H+ <=> 1,2-dihydroxynaphthalene + NADP+ + H2O + CO2 1.14.13.135 1-hydroxy-2-naphthoate hydroxylase
–
erythromycin_D + O2 + NADPH + H+ <=> erythromycin_C + H2O + NADP+ 1.14.13.154 erythromycin 12-hydroxylase
–
MK
raucaffrinoline + NADP+ <=> perakine + NADPH + H+ 1.1.1.317 perakine reductase
–
M
trimethylamine + O2 + NADPH <=> Trimethylamine_N-oxide + H2O + NADP+ 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
MK
phenylacetyl-CoA + O2 + NADPH + H+ <=> 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + NADP+ + H2O 1.14.13.149 phenylacetyl-CoA 1,2-epoxidase
–
BMK
tetrahydrobiopterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
K
eugenol + a_carboxylate + NADP+ <=> a_coniferyl_ester + NADPH 1.1.1.318 eugenol synthase
–
isoeugenol + acetate + NADP+ <=> coniferyl_acetate + NADPH 1.1.1.319 isoeugenol synthase
–
BMK
(S)-benzoin + NADP+ <=> benzil + NADPH + H+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
(R)-benzoin + NADP+ <=> benzil + NADPH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.321 benzil reductase [(R)-benzoin forming]
–
–
(+)-thujan-3-ol + NADP+ <=> (+)-thujan-3-one + NADPH + H+ 1.1.1.323 (+)-thujan-3-ol dehydrogenase
–
(6E)-8-hydroxygeraniol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
K
(6E)-8-hydroxygeraniol + NADP+ <=> (6E)-8-hydroxygeranial + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
M
(6E)-8-hydroxygeraniol + NADP+ <=> (6E)-8-oxogeraniol + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
M
(6E)-8-hydroxygeranial + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
M
(6E)-8-oxogeraniol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
M
L-threo-7,8-dihydrobiopterin + NADP+ <=> sepiapterin + NADPH + H+ 1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
–
(+)-sabinene + NADPH + H+ + O2 <=> (+)-cis-Sabinol + NADP+ + H2O 1.14.13.153 (+)-sabinene 3-hydroxylase
–
(+)-epi-isozizaene + NADPH + H+ + O2 <=> albaflavenone + NADP+ + H2O 1.14.13.106 epi-isozizaene 5-monooxygenase
–
methyl_ecgonine + NADP+ <=> methyl_ecgonone + NADPH + H+ 1.1.1.334 methylecgonone reductase
–
M
(11R)-dihydroartemisinic_aldehyde + NADP+ <=> artemisinic_aldehyde + NADPH + H+ 1.3.1.74 2-alkenal reductase [NAD(P)+]
1.3.1.92 artemisinic aldehyde Delta11(13)-reductase
–
–
BM
H+ + [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + NADPH + O2 <=> [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + NADP+ + H2O 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
–
BM
(+)-Camphor + NADPH + H+ + O2 <=> N-(2-benzyl-3-[[(1R)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]propanoyl)-L-tryptophan + NADP+ + H2O 1.14.13.161 (+)-camphor 6-exo-hydroxylase
–
nicotine_blue_leuco_form + NADP+ <=> nicotine_blue + NADPH + H+ 1.1.1.328 nicotine blue oxidoreductase
–
MK
2-deoxy-scyllo-inosamine + NADP+ <=> 3-amino-2,3-dideoxy-scyllo-inosose + NADPH + H+ 1.1.1.329 2-deoxy-scyllo-inosamine dehydrogenase
–
MK
4-oxo-4-(pyridin-3-yl)butanal + H2O + NADP+ <=> 4-oxo-4-(pyridin-3-yl)butanoate + NADPH + H+ 1.2.1.83 3-succinoylsemialdehyde-pyridine dehydrogenase
–
MK
palmitoyl-CoA + NADPH + H+ <=> hexadecanol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
behenoyl-CoA + NADP+ <=> trans-docos-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
MK
dolichol + NADP+ <=> di-trans,_poly-cis-polyprenol + NADPH + H+ 1.3.1.94 polyprenol reductase
1.3.1.B13
–
–
MK
Nomega-hydroxy-L-arginine + NADPH + O2 <=> L-citrulline + NO + NADP+ + H2O + H+ 1.14.13.39 nitric-oxide synthase (NADPH)
–
MK
a_3alpha-hydroxysteroid + NADP+ <=> 3-keto_steroid + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
3-oxo-5-alpha-steroid + NADP+ <=> a_3-oxo-DELTA4-steroid + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
reduced_adrenodoxin + NADP+ + H+ <=> oxidized_ferredoxin + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.6 adrenodoxin-NADP+ reductase
–
–
(2R)-3-sulfolactate + NADP+ <=> 3-sulfopyruvate + NADPH + H+ 1.1.1.338 (2R)-3-sulfolactate dehydrogenase (NADP+)
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
–
–
BMK
CDP-abequose + NADP+ <=> CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1.341 CDP-abequose synthase
4.2.1
–
–
MK
CDP-3,6-dideoxy-D-glucose + NADP+ <=> CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1.342 CDP-paratose synthase
–
MK
C30_botryococcene + diphosphate + NADP+ <=> presqualene_diphosphate + NADPH + H+ 1.3.1.97 botryococcene synthase
–
M
carboxyspermidine + H2O + NADP+ <=> L-aspartate_4-semialdehyde + putrescine + NADPH + H+ 1.4.1.B4
1.5.1.43 carboxynorspermidine synthase
–
–
BMK
FADH2 + NADP+ <=> FAD + NADPH + H+ 1.14.13.7 phenol 2-monooxygenase (NADPH)
1.18.1.2 ferredoxin---NADP+ reductase
1.5.1.30 flavin reductase (NADPH)
1.5.1.36 flavin reductase (NADH)
1.5.1.38 FMN reductase (NADPH)
1.5.1.41 riboflavin reductase [NAD(P)H]
1.5.1.45 FAD reductase [NAD(P)H]
–
–
–
–
–
–
–
BK
4-nitrocatechol + O2 + NADPH <=> 2-hydroxy-1,4-benzoquinone + nitrite + H2O + NADP+ + H+ 1.14.13.166 4-nitrocatechol 4-monooxygenase
1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
–
–
M
4-nitrophenol + O2 + NADPH + H+ <=> 1,4-benzoquinone + nitrite + H2O + NADP+ 1.14.13.167 4-nitrophenol 4-monooxygenase
1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
–
–
MK
3-Indole-2-oxopropanoate + NADPH + O2 + H+ <=> indole-3-acetic_acid + CO2 + NADP+ + H2O 1.14.13.168 indole-3-pyruvate monooxygenase
–
MK
1-deoxy-11-oxopentalenate + O2 + NADPH + H+ <=> pentalenolactone_D + H2O + NADP+ 1.14.13.170 pentalenolactone D synthase
–
MK
1-deoxy-11-oxopentalenate + O2 + NADPH + H+ <=> neopentalenolactone_D + H2O + NADP+ 1.14.13.171 neopentalenolactone D synthase
–
MK
2-keto-L-gulonate + NADP+ <=> 2,5-didehydro-D-gluconate + NADPH + H+ 1.1.1
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
BM
(+)-lariciresinol + NADP+ <=> (+)-pinoresinol + NADPH + H+ 1.23.1.1 (+)-pinoresinol reductase
1.23.1.2 (+)-lariciresinol reductase
–
–
MK
(-)-secoisolariciresinol + NADP+ <=> (+)-lariciresinol + NADPH + H+ 1.23.1.2 (+)-lariciresinol reductase
–
MK
(-)-lariciresinol + NADP+ <=> (-)-pinoresinol + NADPH + H+ 1.23.1.3 (-)-pinoresinol reductase
1.23.1.4 (-)-lariciresinol reductase
–
–
MK
(+)-secoisolariciresinol + NADP+ <=> (-)-lariciresinol + NADPH + H+ 1.23.1.3 (-)-pinoresinol reductase
1.23.1.4 (-)-lariciresinol reductase
–
–
MK
pyranose + NADP+ <=> an_aldono-1,5-lactone + NADPH + H+ 1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
–
B
agroclavine + NADP+ <=> 6,8-dimethyl-6,7,8,9-tetradehydroergoline + NADPH + H+ 1.5.1.46 agroclavine dehydrogenase
–
MK
5,6,7,8-tetrahydromethanopterin + NADP+ <=> 7,8-dihydromethanopterin + NADPH + H+ 1.5.1.47 dihydromethanopterin reductase [NAD(P)+]
–
BK
2,3-bis-O-phytanyl-sn-glycerol_1-phosphate + NADP+ <=> 2,3-bis-(O-geranylgeranyl)-sn-glycerol_1-phosphate + NADPH + H+ 1.3.1.101 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]
–
BMK
(4R)-4,2''-dihydroxyisoflavan + NADP+ <=> (3R)-2''-hydroxyisoflavanone + NADPH + H+ 1.1.1.348 (3R)-2'-hydroxyisoflavanone reductase
–
(1''S)-averantin + NADP+ <=> norsolorinic_acid + NADPH + H+ 1.1.1.349 norsolorinic acid ketoreductase
1.1.1.B25
–
–
MK
versiconol_acetate + NADP+ <=> versiconal_hemiacetal_acetate + NADPH 1.1.1.353 versiconal hemiacetal acetate reductase
–
MK
versiconol + NADP+ <=> versiconal + NADPH 1.1.1.353 versiconal hemiacetal acetate reductase
–
MK
dihydrochanoclavine-I_aldehyde + NADP+ <=> chanoclavine-I_aldehyde + NADPH + H+ 1.3.1.100 chanoclavine-I aldehyde reductase
–
MK
[2Fe-2S]-center + NADP+ + H+ <=> [2Fe-2S]-center + NADPH 1.18.1.7 ferredoxin---NAD(P)+ reductase (naphthalene dioxygenase ferredoxin-specific)
–
Caffeine + NADPH + O2 + H+ <=> Theobromine + NADP+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
1.14.13.178 methylxanthine N1-demethylase
–
–
BMK
theophylline + NADPH + O2 + H+ <=> 3-Methylxanthine + NADP+ + formaldehyde + H2O 1.14.13.178 methylxanthine N1-demethylase
–
MK
paraxanthine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
1.14.13.178 methylxanthine N1-demethylase
–
–
BMK
Theobromine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O 1.14.13.179 methylxanthine N3-demethylase
–
MK
3-Methylxanthine + NADPH + O2 + H+ <=> xanthine + NADP+ + formaldehyde + H2O 1.14.13.179 methylxanthine N3-demethylase
–
MK
13-deoxydaunorubicin + NADPH + H+ + O2 <=> 13-dihydrodaunorubicin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
BMK
13-dihydrodaunorubicin + NADPH + H+ + O2 <=> daunorubicin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
BMK
aklavinone + NADPH + H+ + O2 <=> epsilon-rhodomycinone + NADP+ + H2O 1.14.13.180 aklavinone 12-hydroxylase
–
BMK
kanamycin_A + NADP+ <=> 2''-dehydrokanamycin_A + NADPH + H+ 1.1.1.355 2'-dehydrokanamycin reductase
–
MK
GDP-beta-L-colitose + NADP+ <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADPH + H+ 1.1.1.356 GDP-L-colitose synthase
–
MK
aklavinone + NADP+ <=> aklaviketone + NADPH + H+ 1.1.1.362 aklaviketone reductase
–
BMK
L-2-chloropropionate + NADP+ <=> 2-chloroacrylate + NADPH + H+ 1.3.1.103 2-haloacrylate reductase
1.3.1.31 2-enoate reductase
–
–
M
NADPH + H+ + O2 <=> NADP+ + H2O 1.6.3.2 NAD(P)H oxidase (H2O-forming)
–
B
Sulfide + NADP+ <=> sulfur + NADPH + H+ 1.12.7.2 ferredoxin hydrogenase
1.8.1.18 NAD(P)H sulfur oxidoreductase (CoA-dependent)
–
–
BM
4-hydroxy-2,5-dimethyl-3(2H)-furanone + NADP+ <=> 4-hydroxy-5-methyl-2-methylene-3(2H)-furanone + NADPH + H+ 1.3.1.105 2-methylene-furan-3-one reductase
–
M
dTDP-6-deoxy-alpha-D-allose + NADP+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-gulose + NADPH + H+ 1.1.1.364 dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase
–
BMK
L-galactonate + NADP+ <=> aldehydo-D-galacturonate + NADPH + H+ 1.1.1.365 D-galacturonate reductase
–
M
5-methyl-1-naphthoate + NADPH + H+ + O2 <=> 3-hydroxy-5-methylnaphthoate + NADP+ + H2O 1.14.13.189 5-methyl-1-naphthoate 3-hydroxylase
–
D-glyceraldehyde + H2O + NADP+ <=> D-glycerate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+)
–
–
–
–
–
–
BK
hexadecanal + CoA + NADP+ <=> stearoyl-CoA + NADPH + H+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
1.2.1.50 long-chain acyl-protein thioester reductase
1.2.1.84 alcohol-forming fatty acyl-CoA reductase
1.2.1.B25
–
–
–
–
K
(R)-2-methylpyrrolidine + NADP+ <=> 2-methyl-1-pyrroline + NADPH + H+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
dTDP-beta-L-evernosamine + NADPH + H+ + O2 <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + NADP+ + H2O 1.14.13.187 L-evernosamine nitrososynthase
–
dTDP-beta-L-evernosamine + NADPH + O2 <=> dTDP-N-hydroxy-beta-L-evernosamine + NADP+ + H2O 1.14.13.187 L-evernosamine nitrososynthase
–
M
dTDP-N-hydroxy-beta-L-evernosamine + NADPH + H+ + O2 <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + NADP+ + H2O 1.14.13.187 L-evernosamine nitrososynthase
–
M
UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+ <=> UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose + NADPH + H+ 1.1.1.367 UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase
–
MK
scyllo-Inositol + NADP+ <=> scyllo-inosose + NADPH + H+ 1.1.1
1.1.1.371 scyllo-inositol 2-dehydrogenase (NADP+)
–
–
K
1,2-dihydro-beta-NAD(P) + H+ + O2 <=> NADP+ + H2O2 1.6.3.5 renalase
–
NADP+ + nicotinate <=> nicotinate-adenine_dinucleotide_phosphate + nicotinamide 2.4.99.20 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
3.2.2.5 NAD+ glycohydrolase
–
–
K
NADP+ <=> 2''-phospho-cyclic_ADP-ribose + nicotinamide 2.4.99.20 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
–
NADP+ + 4-hydroxybutyrate <=> H+ + NADPH + succinate_semialdehyde 1.1.1
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.26 glyoxylate reductase
1.1.1.61 4-hydroxybutyrate dehydrogenase
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.B47
1.1.1.co
–
–
–
–
–
–
–
–
BMK
tetracenomycin_A2 + O2 + NADPH + H+ <=> tetracenomycin_C + H2O + NADP+ 1.14.13.200 tetracenomycin A2 monooxygenase-dioxygenase
–
MK
(S)-2-hydroxyacid + NADP+ <=> a_2-oxo_carboxylate + NADPH + H+ 1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
–
Dihydrosanguinarine + NADP+ <=> sanguinarine + NADPH 1.3.1.107 sanguinarine reductase
–
M
dihydrochelirubine + NADP+ <=> chelirubine + NADPH 1.3.1.107 sanguinarine reductase
–
M
L-allo-threonine + NADP+ <=> aminoacetone + CO2 + NADPH 1.1.1.381 3-hydroxy acid dehydrogenase
–
L-allo-threonine + NADP+ <=> L-2-amino-3-oxobutanoate + NADPH + H+ 1.1.1.276 serine 3-dehydrogenase (NADP+)
1.1.1.381 3-hydroxy acid dehydrogenase
–
–
K
3,6-anhydro-alpha-L-galactopyranose + NADP+ + H2O <=> 3,6-anhydro-L-galactonate + NADPH + H+ 1.2.1.92 3,6-anhydro-alpha-L-galactose dehydrogenase
–
acetyl-CoA + malonyl-CoA + H+ + NADPH <=> 5-methyl-1-naphthoate + CoA + CO2 + H2O + NADP+ 2.3.1.236 5-methylnaphthoic acid synthase
–
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> 10-deoxymethynolide + CoA + CO2 + H2O + NADP+ 2.3.1.239 10-deoxymethynolide synthase
–
MK
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> narbonolide + CoA + CO2 + H2O + NADP+ 2.3.1.240 narbonolide synthase
–
MK
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 2-hydroxy-5-methyl-1-naphthoate + CoA + CO2 + H2O + NADP+ 2.3.1.237 neocarzinostatin naphthoate synthase
–
K
dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+ <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
–
BMK
(4R)-ipsdienol + NADP+ <=> ipsdienone + NADPH + H+ 1.1.1.386 ipsdienol dehydrogenase
–
K
4-hydroxybenzaldehyde + NADP+ + H2O <=> 4-hydroxybenzoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.67 vanillin dehydrogenase
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
1.2.1.96 4-hydroxybenzaldehyde dehydrogenase (NADP+)
–
–
–
–
–
BMK
L-serine + NADP+ <=> L-2-amino-3-oxopropionate + NADPH + H+ 1.1.1.276 serine 3-dehydrogenase (NADP+)
–
(S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP+ <=> L-2-aminoadipate + ATP + NADPH + H+ 1.2.1.95 L-2-aminoadipate reductase
–
K
tetrahydro-L-threo-neopterin + NADP+ <=> H+ + 7,8-dihydro-L-monapterin + NADPH 1.5.1.34 6,7-dihydropteridine reductase
1.5.1.50 dihydromonapterin reductase
–
–
BMK
cholesterol + O2 + NADPH + H+ <=> 7-dehydrocholesterol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
BMK
NADH + H+ + NADP+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> NAD+ + NADPH + oxidized_ferredoxin 1.6.1.4 NAD(P)+ transhydrogenase (ferredoxin)
–
rifampicin + O2 + NADPH <=> 2''-N-hydroxyrifampicin + NADP+ + H2O 1.14.13.211 rifampicin monooxygenase
–
aurachin_C + O2 + NADPH + H+ <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide + NADP+ + H2O 1.14.13.222 aurachin C monooxygenase/isomerase
–
K
(2S)-2-hydroxy-3-oxopropane-1-sulfonic_acid + H2O + NADP+ <=> (S)-3-sulfolactate + NADPH + H+ 1.2.1.97 3-sulfolactaldehyde dehydrogenase
–
M
1,6-dihydro-beta-NAD(P) + H+ + O2 <=> NADP+ + H2O2 1.6.3.5 renalase
–
demethylphylloquinone + NADPH + H+ <=> demethylphylloquinol + NADP+ 1.6.5.12 demethylphylloquinone reductase
–
MK
NADPH + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + CO2 <=> NADP+ + oxidized_ferredoxin + formate 1.17.1.M4
1.2.1.B29
–
–
lithocholic_acid + NADP+ <=> 3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
–
–
–
M
isolithocholic_acid + NADP+ <=> 3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
–
M
bacteriochlorophyll_a + NADP+ <=> geranylgeranyl-bacteriochlorophyllide_a + NADPH + H+ 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase
1.3.1.83 geranylgeranyl diphosphate reductase
–
–
K
4-methyl-5-nitrocatechol + O2 + NADPH <=> H+ + 2-hydroxy-5-methylquinone + NADP+ + nitrite + H2O 1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
–
MK
asperlicin_C + NADPH + H+ + O2 <=> asperlicin_E + NADP+ + H2O 1.14.13.216 asperlicin C monooxygenase
–
M
protodeoxyviolaceinate + O2 + NADPH + H+ <=> protoviolaceinate + NADP+ + H2O 1.14.13.217 protodeoxyviolaceinate monooxygenase
1.14.13.224 violacein synthase
–
–
MK
D-erythritol_1-phosphate + NADP+ <=> D-erythrulose_1-phosphate + NADPH + H+ 1.1.1.402 D-erythritol 1-phosphate dehydrogenase
–
M
resorcinol + NADPH + O2 + H+ <=> Hydroxyquinol + NADP+ + H2O 1.14.13.219 resorcinol 4-hydroxylase (NADPH)
–
MK
(2S,3R)-flavan-3-ol + NADP+ <=> anthocyanidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
aurachin_C + O2 + NADPH + H+ <=> 2-hydroxy-1a-methyl-7a-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one + NADP+ + H2O 1.14.13.222 aurachin C monooxygenase/isomerase
–
M
protoviolaceinate + O2 + NADPH + H+ <=> violaceinate + NADP+ + H2O 1.14.13.224 violacein synthase
–
MK
acetone + O2 + NADPH + H+ <=> methyl_acetate + NADP+ + H2O 1.14.13.226 acetone monooxygenase (methyl acetate-forming)
–
MK
jasmonic_acid + O2 + NADPH + H+ <=> trans-12-hydroxyjasmonate + NADP+ + H2O 1.14.13.228 jasmonic acid 12-hydroxylase
–
M
tert-butanol + O2 + NADPH + H+ <=> isobutane-1,2-diol + NADP+ + H2O 1.14.13.229 tert-butyl alcohol monooxygenase
–
M
tetracycline + O2 + NADPH + H+ <=> 11a-hydroxytetracycline + H2O + NADP+ 1.14.13.231 tetracycline 11a-monooxygenase
–
MK
6-methylpretetramide + NADPH + O2 + H+ <=> 4-hydroxy-6-methylpretetramide + NADP+ + H2O 1.14.13.232 6-methylpretetramide 4-monooxygenase
–
MK
4-hydroxy-6-methylpretetramide + NADPH + O2 + H+ <=> 4-de(dimethylamino)-4-oxoanhydrotetracycline + NADP+ + H2O 1.14.13.233 4-hydroxy-6-methylpretetramide 12a-monooxygenase
–
MK
5a,11a-dehydrotetracycline + O2 + NADPH + H+ <=> 5a,11a-dehydrooxytetracycline + H2O + NADP+ 1.14.13.234 5a,11a-dehydrotetracycline 5-monooxygenase
–
MK
2-methyl-2-butanol + O2 + NADPH + H+ <=> 3-methyl-2-buten-1-ol + NADP+ + H2O 1.14.19.48 tert-amyl alcohol desaturase
–
reduced_flavodoxin + NADP+ <=> flavin + NADPH + H+ 1.19.1.1 flavodoxin---NADP+ reductase
1.6.2.4 NADPH---hemoprotein reductase
–
–
L-arginine + NADP+ + H2O <=> 5-guanidino-2-oxopentanoate + NH3 + NADPH + H+ 1.4.1.25 L-arginine dehydrogenase
–
MK
magnesium_protoporphyrin_monomethyl_ester + O2 + NADPH + H+ <=> 131-hydroxy-magnesium-protoporphyrin_IX_13-monomethyl_ester + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
BMK
131-hydroxy-magnesium-protoporphyrin_IX_13-monomethyl_ester + NADPH + H+ + O2 <=> 131-oxo-magnesium-protoporphyrin_IX_13-monomethyl_ester + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
BMK
131-oxo-magnesium-protoporphyrin_IX_13-monomethyl_ester + O2 + NADPH <=> divinyl_protochlorophyllide_a + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
BMK
4-hydroxybenzoyl-[4-hydroxyphenylalkanoate_synthase] + malonyl-CoA + NADPH + H+ <=> 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
M
N-hydroxyaniline + NADP+ + H2O <=> 4-nitrophenyl + NADPH + H+ 1.7.1.16 nitrobenzene nitroreductase
–
N-hydroxyaniline + NADP+ <=> nitrosobenzene + NADPH + H+ 1.7.1.16 nitrobenzene nitroreductase
–
MK
nitrosobenzene + NADP+ + H2O <=> 4-nitrophenyl + NADPH + H+ 1.7.1.16 nitrobenzene nitroreductase
–
MK
L-arginine + NADPH + H+ + O2 <=> L-citrulline + NO + NADP+ + H2O 1.14.13.39 nitric-oxide synthase (NADPH)
1.14.14.47 nitric-oxide synthase (flavodoxin)
–
–
MK
L-arginine + NADPH + H+ + O2 <=> Nomega-hydroxy-L-arginine + NADP+ + H2O 1.14.13.39 nitric-oxide synthase (NADPH)
–
MK
an_omega-(methylthio)alkyl-glucosinolate + O2 + NADPH + H+ <=> an_omega-(methylsulfinyl)alkyl-glucosinolate + H2O + NADP+ 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
Dimethylamine + O2 + NADPH + H+ <=> methylamine + formaldehyde + H2O + NADP+ 1.14.13.238 dimethylamine monooxygenase
–
M
L-carnitine + O2 + NADPH + H+ <=> (3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O 1.14.13.239 carnitine monooxygenase
–
M
4-hydroxybenzoate + Br- + O2 + NADPH + H+ <=> 2,4-Dibromophenol + CO2 + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
4-hydroxybenzoate + Br- + O2 + NADPH + H+ <=> 3-Bromo-4-hydroxybenzoate + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
M
3-Bromo-4-hydroxybenzoate + Br- + O2 + NADPH + H+ <=> 2,4-Dibromophenol + CO2 + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
M
3,4-dihydroxybenzoate + Br- + O2 + NADPH + H+ <=> 3,5-dibromobenzene-1,2-diol + CO2 + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
3,4-dihydroxybenzoate + Br- + O2 + NADPH + H+ <=> 3-bromo-4,5-dihydroxybenzoic_acid + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
M
3-bromo-4,5-dihydroxybenzoic_acid + Br- + O2 + NADPH + H+ <=> 3,5-dibromobenzene-1,2-diol + CO2 + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
M
dihydro-4-coumaroyl-CoA + NADP+ <=> 4-coumaroyl-CoA + NADPH + H+ 1.3.1.117 hydroxycinnamoyl-CoA reductase
–
MK
dihydroferuloyl-CoA + NADP+ <=> feruloyl-CoA + NADPH + H+ 1.3.1.117 hydroxycinnamoyl-CoA reductase
–
2-polyprenylphenol + O2 + NADPH + H+ <=> 2-polyprenyl-6-hydroxyphenol + H2O + NADP+ 1.14.13.240 2-polyprenylphenol 6-hydroxylase
–
K
3,4-dihydroxyphenyllactic_acid + NADP+ <=> 3,4-Dihydroxyphenylpyruvate + NADPH + H+ 1.1.1.237 hydroxyphenylpyruvate reductase
–
MK
AMP + diphosphate + NADP+ + L-tyrosinal <=> ATP + NADPH + L-tyrosine + H+ 1.2.1.101 L-tyrosine reductase
–
staphylopine + H2O + NADP+ <=> (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + pyruvate + NADPH + H+ 1.5.1.52 staphylopine dehydrogenase
–
M
geranylgeranyl_diphosphate + NADPH + H+ <=> lycopaoctaene + NADP+ + diphosphate 2.5.1.148 lycopaoctaene synthase
–
prephytoene_diphosphate + NADPH + H+ <=> lycopaoctaene + NADP+ + diphosphate 2.5.1.148 lycopaoctaene synthase
–
M
malonyl-CoA + NADPH + NADH + H+ <=> (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + CoA + CO2 + NADP+ + NAD+ + H2O 2.3.1.281 5-hydroxydodecatetraenal polyketide synthase
–
M
a_3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP+ <=> a_4alpha-methyl-3-oxosteroid + CO2 + NADPH 1.1.1.417 3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating)
–
a_palmitoyl-[(hydroxy)phthioceranic_acid_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> C40-phthioceranyl-[(hydroxy)phthioceranic_acid_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.287 phthioceranic/hydroxyphthioceranic acid synthase
–
a_palmitoyl-[(hydroxy)phthioceranic_acid_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> C37-phthioceranyl-[(hydroxy)phthioceranic_acid_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.287 phthioceranic/hydroxyphthioceranic acid synthase
–
cyclohexanecarboxyl-CoA + NADP+ <=> cyclohex-1-ene-1-carbonyl-CoA + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+)
–
–
M
4-nitrobenzoyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> demethylluteothin + CO2 + CoA + NADP+ + H2O 2.3.1.289 aureothin polyketide synthase system
–
4-nitrobenzoyl-CoA + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> demethyldeoxyspectinabilin + CO2 + CoA + NADP+ + H2O 2.3.1.290 spectinabilin polyketide synthase system
–
19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C37-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + CO2 + CoA + NADP+ + H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
M
17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C35-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + CO2 + CoA + NADP+ + H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
M
(S)-8-oxocitronellyl_enol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.3.1.122 (S)-8-oxocitronellyl enol synthase
–
MK
(R)-8-oxocitronellyl_enol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.3.1.123 8-oxogeranial reductase
–
proline_betaine + NADPH + O2 + H+ <=> N-methyl-L-proline + formaldehyde + NADP+ + H2O 1.14.13.247 stachydrine N-demethylase
–
M
NADP+ + H2O <=> NAD+ + phosphate 3.1.3
3.1.3.1 alkaline phosphatase
3.1.3.108 nocturnin
–
–
–
MK
trans-2-enoyl-CoA + NADP+ <=> a_(2E,4Z)-2,4-dienoyl-CoA + NADPH + H+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
trans-3-enoyl-CoA + NADP+ <=> trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
M
trans-3-enoyl-CoA + NADP+ <=> a_(2E,4Z)-2,4-dienoyl-CoA + NADPH + H+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
M
D-xylose + NADP+ <=> D-xylono-1,4-lactone + NADPH + H+ 1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
–
MK
benzoyl-CoA + O2 + NADPH + H+ <=> 3-hydroxybenzoyl-CoA + H2O + NADP+ 1.14.13.58 benzoyl-CoA 3-monooxygenase
–
BM
3-hydroxyphenylacetate + NADPH + O2 + H+ <=> homogentisate + NADP+ + H2O 1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase
–
K
NADPH + O2 + 4-hydroxybenzoate + H+ <=> NADP+ + CO2 + H2O + hydroquinone 1.14.13.64 4-hydroxybenzoate 1-hydroxylase
–
K
2-Hydroxycyclohexan-1-one + O2 + NADPH + H+ <=> 1-Oxa-2-oxo-7-hydroxycycloheptane + H2O + NADP+ 1.14.13.66 2-hydroxycyclohexanone 2-monooxygenase
–
K
NADP+ + codeine <=> H+ + NADPH + codeinone 1.1.1.218 morphine 6-dehydrogenase
1.1.1.247 codeinone reductase (NADPH)
–
–
MK
NADP+ + salutaridinol <=> H+ + NADPH + salutaridine 1.1.1.248 salutaridine reductase (NADPH)
–
MK
NADP+ + Scytalone <=> H+ + NADPH + 1,3,6,8-Tetrahydroxynaphthalene 1.1.1.252 tetrahydroxynaphthalene reductase
–
glycolaldehyde + NADP+ <=> Glyoxal + NADPH + H+ 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
1-butanol + NADP+ <=> H+ + Butyraldehyde + NADPH 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
–
–
–
MK
trans-2-hexenol + NADP+ <=> trans-2-hexenal + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.265 3-methylbutanal reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
M
furfural + NADPH + H+ <=> Furfuryl_alcohol + NADP+ 1.1.1
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.265 3-methylbutanal reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
fatty_acid + O2 + NADPH + H+ <=> omega-hydroxy_fatty_acid + NADP+ + H2O 1.14.13
1.14.15.3 alkane 1-monooxygenase
–
–
M
(3R)-3-hydroxybutanoyl-[acyl-carrier_protein] + NADP+ <=> acetoacetyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
BMK
1-alkyl-sn-glycero-3-phosphate + NADP+ <=> O-alkylglycerone_phosphate + NADPH + H+ 1.1.1.101 acylglycerone-phosphate reductase
–
MK
(S)-2-amino-1-(R)-3-dihydroxyeicosane + NADP+ <=> (S)-2-amino-1-hydroxyeicosane-3-one + NADPH + H+ 1.1.1.102 3-dehydrosphinganine reductase
–
M
4-nitrobenzyl_alcohol + NADP+ <=> 4-nitrobenzaldehyde + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.220 6-pyruvoyltetrahydropterin 2'-reductase
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.65 pyridoxine 4-dehydrogenase
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
chenodeoxycholic_acid + NADP+ <=> 7alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
glycolaldehyde + H+ + NADPH <=> ethylene_glycol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
M
acetoin + NADP+ <=> diacetyl + NADPH + H+ 1.1.1
1.1.1.10 L-xylulose reductase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.162 erythrulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.2.1.3 aldehyde dehydrogenase (NAD+)
–
–
–
–
–
–
–
–
–
–
–
–
–
–
2-phenylethanol + NADP+ <=> phenylacetaldehyde + NADPH + H+ 1.1.1
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.90 aryl-alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
M
Vanillyl_alcohol + NADP+ <=> Vanillin + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.2.1
–
–
–
isobutanol + NADP+ <=> Isobutyraldehyde + NADPH + H+ 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
sinapyl_alcohol + NADP+ <=> sinapaldehyde + NADPH + H+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
BMK
ursocholate + NADP+ <=> 3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic_acid + NADPH + H+ 1.1.1.159 7alpha-hydroxysteroid dehydrogenase
1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
–
M
5alpha-androstane-3alpha,17beta-diol + NADP+ <=> 5alpha-dihydrotestosterone + NADPH + H+ 1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
K
L-Idonate + NADP+ <=> 2-keto-L-gulonate + NADPH + H+ 1.1.1
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
–
BM
5-Dehydro-D-gluconate + NADP+ <=> H+ + 2,5-didehydro-D-gluconate + NADPH 1.1.1
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
BM
Apiforol + NADP+ <=> naringenin + NADPH + H+ 1.1.1.234 flavanone 4-reductase
–
MK
luteoforol + NADP+ <=> eriodictyol + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
1.1.1.234 flavanone 4-reductase
–
–
MK
4alpha-methylcholest-7-en-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
avenasterol + NADP+ <=> avenastenone + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
MK
cycloeucalenol + NADP+ <=> cycloeucalenone + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
MK
(3R)-hydroxybutyryl-CoA + NADP+ <=> acetoacetyl-CoA + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase
1.1.1.36 acetoacetyl-CoA reductase
–
–
–
BMK
D-mannonate + NADP+ <=> D-fructuronate + NADPH + H+ 1.1.1
1.1.1.57 fructuronate reductase
–
–
cis-3-hexenal + NADPH + H+ <=> (3Z)-hex-3-en-ol + NADP+ 1.1.1
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
M
trans-2-pentenol + NADP+ <=> trans-2-pentenal + NADPH + H+ 1.1.1
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
M
Hydroxyacetone + NADP+ <=> H+ + methylglyoxal + NADPH 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
MK
5-Oxopentanoate + NADP+ + H2O <=> Glutarate + NADPH + H+ 1.2.1
1.2.1.20 glutarate-semialdehyde dehydrogenase
–
–
M
H+ + sinapoyl-CoA + NADPH <=> sinapaldehyde + NADP+ + CoA 1.2.1.44 cinnamoyl-CoA reductase
–
K
4-coumaroyl-CoA + NADPH + H+ <=> 4-coumaraldehyde + CoA + NADP+ 1.2.1.44 cinnamoyl-CoA reductase
–
BMK
H+ + feruloyl-CoA + NADPH <=> coniferyl_aldehyde + NADP+ + CoA 1.2.1.44 cinnamoyl-CoA reductase
1.2.1.68 coniferyl-aldehyde dehydrogenase
–
–
BMK
methylglyoxal + NADP+ + H2O <=> H+ + pyruvate + NADPH 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.23 2-oxoaldehyde dehydrogenase (NAD+)
1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
–
–
MK
4,4-dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> H+ + 4,4-dimethyl-5-alpha-cholesta-8,14-dien-3-beta-ol + NADPH 1.3.1.70 Delta14-sterol reductase
–
M
cholesterol + NADP+ <=> desmosterol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
MK
24,25-dihydrolanosterol + NADP+ <=> lanosterol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
MK
4,4-dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
MK
cycloartanol + NADP+ <=> Cycloartenol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
M
methyl-1,4-benzoquinone + NADPH + H+ <=> methylhydroquinone + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.6.5
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
deoxycholate + NADP+ <=> 4-(1-Naphthylvinyl)pyridine + NADPH + H+ 1.1.1.176 12alpha-hydroxysteroid dehydrogenase
–
p-coumaryl_alcohol + NADP+ <=> 4-coumaraldehyde + NADPH + H+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
BMK
Leucocyanidin + NADP+ <=> taxifolin + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
MK
cis-3,4-leucopelargonidin + NADP+ <=> (+)-dihydrokaempferol + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
MK
3,4-cis-leucodelphinidin + NADP+ <=> dihydromyricetin + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
MK
2,5-dihydroxybenzaldehyde + NADP+ + H2O <=> 2,5-Dihydroxybenzoate + NADPH + H+ 1.2.1
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
3-Hydroxybenzaldehyde + NADP+ + H2O <=> 3-hydroxybenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
–
–
MK
acetaldehyde + NADP+ + H2O <=> acetate + NADPH + H+ 1.2.1
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
–
–
–
–
–
–
–
–
–
BMK
propionaldehyde + H2O + NADP+ <=> propionate + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.22 lactaldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
1.5.1.6 formyltetrahydrofolate dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
M
Dihydrothymine + NADP+ <=> thymine + NADPH + H+ 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
–
BM
prostaglandin_F2alpha + NADP+ <=> prostaglandin_H2 + NADPH + H+ 1.1.1
1.1.1.188 prostaglandin-F synthase
1.1.1.189 prostaglandin-E2 9-reductase
1.6.99.1 NADPH dehydrogenase
–
–
–
–
K
cholic_acid + NADP+ <=> 7alpha,12alpha-dihydroxy-5beta-cholan-3-one-24-oic_acid + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.52 3alpha-hydroxycholanate dehydrogenase (NAD+)
–
–
–
–
deoxycholate + NADP+ <=> 12alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1
1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
M
5beta-androstane-3,17-dione + NADP+ <=> 4-androstene-3,17-dione + NADPH + H+ 1.3.1
1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
–
K
7alpha,12alpha-dihydroxy-4-cholesten-3-one + NADPH + H+ <=> 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
BMK
acrolein + NADPH + H+ <=> propionaldehyde + NADP+ 1.3.1
1.3.1.27 2-hexadecenal reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
1.6.99.1 NADPH dehydrogenase
–
–
–
–
–
–
M
5alpha-dihydroprogesterone + NADP+ <=> progesterone + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
–
–
MK
5alpha-dihydrotestosterone + NADP+ <=> testosterone + H+ + NADPH 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
–
–
MK
trans-2-decenoyl-CoA + NADP+ <=> 2-trans,4-cis-decadienoyl-CoA + NADPH + H+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
17alpha,21-dihydroxy-5alpha-pregnan-3,11,20-trione + NADP+ <=> cortisone + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
(3R)2',7-dihydroxy-dihydro-4',5'-methylenedioxyisoflavone + NADP+ <=> 2''-hydroxypseudobaptigenin + NADPH + H+ 1.3.1.45 2'-hydroxyisoflavone reductase
–
MK
3-buten-2-one + NADPH + H+ <=> 2-butanone + NADP+ 1.3.1
1.3.1.27 2-hexadecenal reductase
1.3.1.31 2-enoate reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
–
–
–
–
–
–
M
1-penten-3-one + NADPH + H+ <=> 3-Pentanone + NADP+ 1.3.1
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
–
–
–
M
palmitoyl-CoA + NADP+ <=> trans-2-hexadecenoyl-CoA + NADPH + H+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
BMK
arachidoyl-CoA + NADP+ <=> (2E)-eicosenoyl-CoA + NADPH + H+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
1.3.1.93 very-long-chain enoyl-CoA reductase
–
–
M
2,5-Diaminohexanoate + H2O + NADP+ <=> 2-Amino-5-oxohexanoate + NH3 + NADPH + H+ 1.4.1.12 2,4-diaminopentanoate dehydrogenase
–
L-pipecolic_acid + NADP+ <=> DELTA1-piperidine_6-carboxylate + NADPH + H+ 1.5.1
1.5.1.2 pyrroline-5-carboxylate reductase
–
–
M
ascorbate + NADP+ + H+ <=> ascorbate + NADPH 1.6.5
1.6.5.4 monodehydroascorbate reductase (NADH)
–
–
M
dihydrolipoamide + NADP+ <=> Lipoamide + NADPH + H+ 1.8.1
1.8.1.4 dihydrolipoyl dehydrogenase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
5alpha-Cholestan-3-one + NADP+ <=> cholest-4-en-3-one + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
stearoyl-CoA + NADPH + O2 + H+ <=> oleoyl-CoA + NADP+ + H2O 1.14.19
1.14.19.1 stearoyl-CoA 9-desaturase
1.14.19.M26
–
–
–
K
N-ethylsuccinimide + NADP+ <=> N-ethylmaleimide + NADPH + H+ 1.14.13.40 anthraniloyl-CoA monooxygenase
1.3.1
1.3.1.31 2-enoate reductase
–
–
–
H+ + Cyclohexane + O2 + NADPH <=> Cyclohexanol + H2O + NADP+ 1.14.13.25 methane monooxygenase (soluble)
1.14.15.3 alkane 1-monooxygenase
–
–
ethyl_(2R)-methyl-(3S)-hydroxybutanoate + NADP+ <=> ethyl_2-methylacetoacetate + NADPH + H+ 1.1.1
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
–
–
tetrahydrobiopterin + NADP+ <=> (6R)-L-erythro-6,7-dihydrobiopterin + NADPH + H+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
1.5.1.34 6,7-dihydropteridine reductase
–
–
–
K
(-)-limonene + O2 + NADPH + H+ <=> (-)-cis-carveol + H2O + NADP+ 1.14.13
1.14.14.53 (R)-limonene 6-monooxygenase
–
–
NADPH + vitamin_K + H+ <=> NADP+ + vitamin_KH2 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
M
4alpha-methyl-5alpha-ergosta-8,24-dien-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH + H+ 1.3.1.70 Delta14-sterol reductase
–
MK
desmosterol + NADP+ <=> Cholesta-5,7,24-trienol + NADPH + H+ 1.3.1.21 7-dehydrocholesterol reductase
–
M
H+ + 3-hydroxypropionate + ATP + CoA + NADPH <=> propionyl-CoA + AMP + diphosphate + H2O + NADP+ 6.2.1.17 propionate---CoA ligase
–
cortisol + NADP+ <=> cortisone + NADPH + H+ 1.1.1
1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.B40
–
–
–
K
sitosterol + NADP+ <=> isofucosterol + NADPH + H+ 1.3.1
1.3.1.70 Delta14-sterol reductase
1.3.1.72 Delta24-sterol reductase
1.3.1.M20
–
–
–
–
K
11-cis-retinol + NADP+ <=> 11-cis-retinal + NADPH + H+ 1.1.1
1.1.1.300 NADP-retinol dehydrogenase
1.1.1.315 11-cis-retinol dehydrogenase
–
–
–
K
3-aminopropionaldehyde + NADP+ + H2O <=> beta-Alanine + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
BM
4-Aminobutyraldehyde + NADP+ + H2O <=> 4-aminobutanoate + NADPH + H+ 1.2.1
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
–
–
–
K
4-hydroxybutanal + NADPH + H+ <=> 1,4-Butanediol + NADP+ 1.1.1
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
epicatechin + NADP+ <=> cyanidin + NADPH + H+ 1.17.1.3 leucoanthocyanidin reductase
1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
–
MK
epigallocatechin + NADP+ <=> delphinidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
MK
(-)-epiafzelechin + NADP+ <=> H+ + pelargonidin + NADPH 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
MK
UDP-L-rhamnose + NADP+ <=> UDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ 1.1.1
1.1.1.133 dTDP-4-dehydrorhamnose reductase
–
–
Zymosterol + NADP+ <=> H+ + zymosterone + NADPH 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
BMK
3-chlorophenol + O2 + NADPH + H+ <=> 4-Chlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
1.14.13.7 phenol 2-monooxygenase (NADPH)
–
–
M
2-chlorophenol + O2 + NADPH + H+ <=> 3-chlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
1.14.13.7 phenol 2-monooxygenase (NADPH)
–
–
M
H+ + (+)-isomenthone + NADPH <=> (+)-isomenthol + NADP+ 1.1.1.208 (+)-neomenthol dehydrogenase
–
M
H+ + (+)-isomenthone + NADPH <=> d-neoisomenthol + NADP+ 1.1.1.207 (-)-menthol dehydrogenase
–
M
L-threo-(6R,1'S,2'S)-5,6,7,8-tetrahydrobiopterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
–
–
Nicotine + NADPH + O2 <=> nicotine-1''-N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
M
4-Chlorophenol + O2 + NADPH + H+ <=> 4-Chlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
1.14.13.7 phenol 2-monooxygenase (NADPH)
–
–
MK
4-nitrophenol + NADPH + O2 + H+ <=> 4-nitrocatechol + NADP+ + H2O 1.14.13.29 4-nitrophenol 2-monooxygenase
–
(R)-2-hydroxyisocaproate + NADP+ <=> 4-methyl-2-oxopentanoate + NADPH + H+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
–
D-2-hydroxybutyrate + NADP+ <=> 2-oxobutyrate + NADPH + H+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
1.1.1.28 D-lactate dehydrogenase
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
–
palmitoyl-CoA + NADPH + O2 + H+ <=> palmitoleoyl-CoA + NADP+ + H2O 1.14.19.1 stearoyl-CoA 9-desaturase
1.14.19.M26
–
–
5beta-pregnane-3,20-dione + NADP+ <=> progesterone + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
1.3.1.M16
1.3.99.6 3-oxo-5beta-steroid 4-dehydrogenase
–
–
–
–
–
MK
trans-phytenoyl-CoA + NADPH + H+ <=> phytanoyl-CoA + NADP+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
–
M
(4R)-dihydrocarvone + NADPH + H+ + O2 <=> (4R)-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(1R,4S)-1-hydroxy-2-oxolimonene + O2 + NADPH <=> (3S)-3-isopropenyl-6-oxoheptanoate + H2O + NADP+ 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
(1S,4R)-1-hydroxy-2-oxolimonene + O2 + NADPH <=> (3R)-3-isopropenyl-6-oxoheptanoate + H2O + NADP+ 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
(1S,4R)-menthone + NADPH + H+ + O2 <=> (4S,7R)-7-isopropyl-4-methyl-2-oxo-oxepanone + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
13,14-dihydro-15-keto-prostaglandin_E2 + NADP+ <=> 15-ketoprostaglandin_E2 + NADPH + H+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
7alpha-hydroxy-4-cholesten-3-one + NADPH + H+ <=> 7alpha-hydroxy-5beta-cholestan-3-one + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
BMK
dodecanoyl-[acyl-carrier_protein] + NADP+ <=> dodecenoyl-[Staphylococcus_aureus_acyl_carrier_protein] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
L-lactaldehyde + NADP+ + H2O <=> L-lactate + NADPH + H+ 1.2.1
1.2.1.22 lactaldehyde dehydrogenase
–
–
BM
3-sulfopropanal + NADP+ + H2O <=> 3-Sulfopropanoate + NADPH + H+ 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
–
M
1,3-Propanediol + NADP+ <=> 3-hydroxypropionaldehyde + NADPH + H+ 1.1.1
1.1.1.202 1,3-propanediol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
M
hexanal + CoA + NADP+ <=> hexanoyl-CoA + NADPH + H+ 1.2.1
1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)
–
–
M
7-hydroxymethylchlorophyll_a + NADP+ <=> chlorophyll_b + NADPH 1.1.1.294 chlorophyll(ide) b reductase
–
BMK
Ethionamide + NADPH + O2 + H+ <=> ethionamide_S-oxide + NADP+ + H2O 1.14.13
1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
–
–
M
3-hydroxypropionaldehyde + NADP+ + H2O <=> 3-hydroxypropionate + NADPH + H+ 1.2.1.99 4-(gamma-glutamylamino)butanal dehydrogenase
–
(R)-2-methylmalonyl-CoA + NADP+ <=> acryloyl-CoA + CO2 + NADPH 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
M
triethylamine + O2 + NADPH + H+ <=> Triethylamine_N-oxide + H2O + NADP+ 1.14.13
1.14.13.8 flavin-containing monooxygenase
–
–
M
erythromycin_B + O2 + NADPH + H+ <=> erythromycin + H2O + NADP+ 1.14.13.154 erythromycin 12-hydroxylase
–
MK
Caffeine + NADPH + O2 + H+ <=> paraxanthine + NADP+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
1.14.13.179 methylxanthine N3-demethylase
1.14.14.1 unspecific monooxygenase
–
–
–
MK
trans-anol + acetate + NADP+ <=> 4-coumaryl_acetate + NADPH 1.1.1
1.1.1.319 isoeugenol synthase
–
–
MK
eugenol + acetate + NADP+ <=> coniferyl_acetate + NADPH 1.1.1.318 eugenol synthase
–
BMK
(3R,4R)-7,2''-dihydroxy-4''-methoxyisoflavanol + NADP+ <=> vestitone + NADPH + H+ 1.1.1.348 (3R)-2'-hydroxyisoflavanone reductase
–
MK
13-deoxycarminomycin + NADPH + H+ + O2 <=> 13-dihydrocarminomycin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
BMK
13-dihydrocarminomycin + NADPH + H+ + O2 <=> carminomycin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
BMK
daunorubicin + NADPH + H+ + O2 <=> doxorubicin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
MK
5,5''-dimethoxylariciresinol + NADP+ <=> (+/-)-syringaresinol + NADPH + H+ 1.23.1
1.23.1.1 (+)-pinoresinol reductase
–
–
(3R)-3-hydroxy-arachidoyl-CoA + NADP+ <=> 3-oxo-arachidoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(3R)-3-hydroxy-lignoceroyl-CoA + NADP+ <=> 3-oxo-lignoceroyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
2-hydroxypropiophenone + NADP+ <=> 1-phenyl-1,2-propanedione + NADPH + H+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> 3-dehydro-4-methylzymosterol + NADPH + CO2 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
BMK
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-cholesta-8-en-3-one + NADPH + CO2 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
M
4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> zymosterone + NADPH + CO2 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
BMK
4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 5alpha-cholesta-8-en-3-one + CO2 + NADPH 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
M
4alpha-methylzymosterol + NADP+ <=> H+ + 3-dehydro-4-methylzymosterol + NADPH 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
MK
5beta-cholestane-3alpha,7alpha,12alpha-triol + NADP+ <=> 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
BMK
5beta-cholestane-3alpha,7alpha-diol + NADP+ <=> 7alpha-hydroxy-5beta-cholestan-3-one + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
BMK
epsilon-rhodomycinone + NADP+ <=> maggiemycin + NADPH + H+ 1.1.1.362 aklaviketone reductase
–
cis-3,4-dehydroadipyl-CoA_semialdehyde + NADP+ + H2O <=> cis-3,4-dehydroadipyl-CoA + NADPH + H+ 1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
–
MK
4-chloro-2-methylphenol + O2 + NADPH + H+ <=> 3-methyl-5-chlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
–
M
4-hexen-3-one + NADPH + H+ <=> hexan-3-one + NADP+ 1.3.1
1.3.1.74 2-alkenal reductase [NAD(P)+]
–
–
M
ursodeoxycholate + NADP+ <=> 7-ketolithocholic_acid + NADPH + H+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
M
chlorophyllide_a + NADP+ <=> divinyl_chlorophyllide_a + NADPH + H+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
MK
hexadecanal + [acyl-carrier_protein] + NADP+ <=> palmitoyl-[acyl-carrier_protein] + NADPH + H+ 1.2.1.50 long-chain acyl-protein thioester reductase
1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
–
–
M
3,4-Dihydroxybenzaldehyde + NADP+ + H2O <=> 3,4-dihydroxybenzoate + NADPH + H+ 1.2.1.67 vanillin dehydrogenase
–
M
UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + NADPH + H+ 1.1.1.367 UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase
–
tetracenomycin_B2 + O2 + NADPH + H+ <=> 8-demethyltetracenomycin_C + H2O + NADP+ 1.14.13.200 tetracenomycin A2 monooxygenase-dioxygenase
–
BMK
chelerythrine + NADPH <=> Dihydrochelerythrine + NADP+ 1.3.1.107 sanguinarine reductase
–
M
3-Methyl-4-hydroxybenzaldehyde + NADP+ + H2O <=> 4-hydroxy-3-methylbenzoate + NADPH + H+ 1.2.1.96 4-hydroxybenzaldehyde dehydrogenase (NADP+)
–
MK
reduced_ferredoxin_[iron-sulfur]_cluster + NADPH + H+ <=> oxidized_ferredoxin + NADP+ + H2 1.17.1.M4
1.2.1.B29
–
–
3beta,12alpha-dihydroxy-5beta-cholanoate + NADP+ <=> 12alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
–
M
3 beta-hydroxy-7,12-diketocholanate + NADP+ <=> dehydrocholate + NADPH + H+ 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
–
a_3beta-hydroxysteroid-4alpha-carboxylate + NADP+ <=> 3-keto_steroid + NADPH + CO2 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
bilirubin_IXbeta + NADP+ <=> biliverdin_IXbeta + NADPH + H+ 1.3.1.24 biliverdin reductase
–
isocitrate + NADP+ <=> oxalosuccinate + NADPH + H+ 1.1.1.42 isocitrate dehydrogenase (NADP+)
–
K
4-chloro-N-hydroxyaniline + NADP+ + H2O <=> 4-chloronitrobenzene + NADPH + H+ 1.7.1.16 nitrobenzene nitroreductase
–
4-nitrotoluene + NADPH + H+ <=> 4-hydroxyaminotoluene + H2O + NADP+ 1.7.1
1.7.1.16 nitrobenzene nitroreductase
–
–
M
octadecanal + NADP+ + [acyl-carrier_protein] <=> stearoyl-[acyl-carrier_protein] + NADPH + H+ 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
–
M
4-hydroxybutanoyl-CoA + NADPH + H+ <=> 4-hydroxybutanal + NADP+ + CoA 1.2.1.57 butanal dehydrogenase
–
(2R,3R,6S)-Virginiae_butanolide-A + NADP+ <=> 6-dehydro-Virginiae_butanolide-A + NADPH + H+ 1.1.1.413 A-factor type gamma-butyrolactone 1'-reductase (1S-forming)
–
glucoerucin + O2 + NADPH + H+ <=> 4-methylsulfinylbutylglucosinolate + H2O + NADP+ 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
M
myristoyl-CoA + NADPH + H+ <=> Tetradecanol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
stearoyl-CoA + NADPH + H+ <=> octadecanol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
campesterol + NADP+ <=> 24-methylene_cholesterol + NADPH + H+ 1.3.1
1.3.1.72 Delta24-sterol reductase
1.3.1.M20
–
–
–
K
4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate_6-semialdehyde + NADP+ <=> stizolobate + NADPH + H+ 1.13.11.29 stizolobate synthase
–
K
2'-Hydroxydihydrogenistein + NADP+ <=> 2''-hydroxygenistein + NADPH + H+ 1.3.1.51 2'-hydroxydaidzein reductase
–
M
L-Xylose + NADP+ <=> L-xylono-1,4-lactone + NADPH + H+ 1.1.1.113 L-xylose 1-dehydrogenase
1.1.1.116 D-arabinose 1-dehydrogenase (NAD+)
1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.B35
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
D-ribose + NADP+ + H2O <=> D-ribonate + NADPH + H+ 1.1.1.115 ribose 1-dehydrogenase (NADP+)
–
D-galactose + NADP+ <=> D-galactono-1,5-lactone + NADPH + H+ 1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
K
L-sorbose + NADP+ <=> 5-dehydro-D-fructose + NADPH + H+ 1.1.1.123 sorbose 5-dehydrogenase (NADP+)
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
D-fructose + NADP+ <=> 5-dehydro-D-fructose + NADPH + H+ 1.1.1.124 fructose 5-dehydrogenase (NADP+)
1.1.1.69 gluconate 5-dehydrogenase
–
–
D-mannitol + NADP+ <=> D-fructose + NADPH + H+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.14 L-iditol 2-dehydrogenase
1.1.1.21 aldose reductase
1.1.1.287 D-arabinitol dehydrogenase (NADP+)
1.1.1.289 sorbose reductase
1.1.1.67 mannitol 2-dehydrogenase
–
–
–
–
–
–
K
L-gulonate + NADP+ <=> D-glucuronate + NADPH + H+ 1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.20 glucuronolactone reductase
1.1.1.21 aldose reductase
–
–
–
–
BK
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.21 aldose reductase
1.1.1.220 6-pyruvoyltetrahydropterin 2'-reductase
–
–
–
–
K
(R)-mevalonate + NADP+ <=> DL-mevaldate + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.32 mevaldate reductase
1.1.1.33 mevaldate reductase (NADPH)
–
–
–
(R)-3-hydroxyvaleryl-CoA + NADP+ <=> 3-oxoacyl-CoA + NADPH + H+ 1.1.1.36 acetoacetyl-CoA reductase
–
R-CHOH-R' + NADP+ <=> acetone + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
–
D-arabinose + NADP+ <=> D-arabinono-1,4-lactone + NADPH + H+ 1.1.1.113 L-xylose 1-dehydrogenase
1.1.1.116 D-arabinose 1-dehydrogenase (NAD+)
1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.122 D-threo-aldose 1-dehydrogenase
1.1.1.B35
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
BK
1,2-propanediol + NADP+ <=> L-lactaldehyde + NADPH + H+ 1.1.1.21 aldose reductase
1.1.1.55 lactaldehyde reductase (NADPH)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
acyl-[acyl-carrier_protein] + NADP+ <=> trans-2,3-dehydroacyl-[acyl-carrier_protein] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
–
–
–
–
K
5-methyltetrahydrofolate + NADP+ <=> 5,10-methylenetetrahydrofolate + NADPH + H+ 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H]
–
BK
10-formyltetrahydrofolate + H2O + NADP+ <=> tetrahydrofolate + CO2 + NADPH + H+ 1.5.1.6 formyltetrahydrofolate dehydrogenase
–
K
chlorophyllide_a + NADP+ <=> protochlorophyllide + NADPH + H+ 1.3.1.33 protochlorophyllide reductase
–
BK
thioredoxin + NADP+ <=> thioredoxin_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
1.8.1.B1
–
–
M
(-)-menthol + O2 + NADPH + H+ <=> p-Menthane-3,8-diol + H2O + NADP+ 1.14.13.46 (-)-menthol monooxygenase
–
protein-dithiol + NADP+ <=> protein_disulfide + NADPH + H+ 1.8.1.8 protein-disulfide reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
3-Hydroxy-2-methylpyridine-5-carboxylate + NADPH + H+ + O2 <=> 2-(Acetamidomethylene)succinate + NADP+ 1.14.13.242 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase
–
K
dUMP + 5,10-methylenetetrahydrofolate + NADPH + H+ <=> dTMP + tetrahydrofolate + NADP+ 1.5.1.3 dihydrofolate reductase
2.1.1.148 thymidylate synthase (FAD)
–
–
MK
(S)-4-Amino-5-oxopentanoate + NADP+ + tRNAMet <=> Glu-tRNAGln + NADPH + H+ 1.2.1.70 glutamyl-tRNA reductase
–
BK
sorbitol + NADP+ <=> L-sorbose + NADPH + H+ 1.1.1.14 L-iditol 2-dehydrogenase
1.1.1.289 sorbose reductase
1.1.1.B60
1.1.99.21 D-sorbitol dehydrogenase (acceptor)
–
–
–
–
K
7-hydroxychlorophyllide_a + NADP+ <=> chlorophyllide_b + NADPH + H+ 1.1.1.294 chlorophyll(ide) b reductase
–
K
(+)-limonene + NADPH + H+ + O2 <=> (R)-1,2-epoxy-limonene + NADP+ + H2O 1.14.13.107 limonene 1,2-monooxygenase
–
MK
hexadecanal + [acyl-carrier_protein] + NADP+ <=> stearoyl-[acyl-carrier_protein] + NADPH + H+ 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
–
10beta-hydroxytaxa-4(20),11-dien-5alpha-yl_acetate + O2 + NADPH + H+ <=> 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl_acetate + NADP+ + H2O 1.14.13.146 taxoid 14beta-hydroxylase
–
BK
taxusin + O2 + NADPH + H+ <=> 7beta-hydroxytaxusin + NADP+ + H2O 1.14.13.147 taxoid 7beta-hydroxylase
–
(-)-endo-fenchol + NADP+ <=> (+)-fenchone + NADPH + H+ 1.1.1.322 (-)-endo-fenchol dehydrogenase
–
L-threo-tetrahydrobiopterin + 2 NADP+ <=> 6-pyruvoyltetrahydropterin + 2 NADPH + 2 H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
–
–
K
a_very-long-chain_(3R)-3-hydroxyacyl-CoA + NADP+ <=> a_very-long-chain_3-oxoacyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
K
7-hydroxychlorophyllide_a + O2 + NADPH + H+ <=> chlorophyllide_b + 2 H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
BK
versicolorone + NADP+ <=> 1'-hydroxyversicolorone + NADPH 1.1.1.353 versiconal hemiacetal acetate reductase
–
MK
L-arabinose + NADP+ <=> L-arabinono-1,4-lactone + NADPH + H+ 1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.46 L-arabinose 1-dehydrogenase
–
–
–
–
BK
L-rhamnose + NADP+ <=> L-Rhamno-1,4-lactone + NADPH + H+ 1.1.1.173 L-rhamnose 1-dehydrogenase
1.1.1.377 L-rhamnose 1-dehydrogenase (NADP+)
1.1.1.378 L-rhamnose 1-dehydrogenase [NAD(P)+]
–
–
–
BK
5-dehydroepisterol + NADPH + H+ + O2 <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP+ + 2 H2O 1.14.19.41 sterol 22-desaturase
–
K
[F-actin]-L-methionine + NADPH + O2 + H+ <=> [F-actin]-L-methionine-(R)-S-oxide + NADP+ + H2O 1.14.13.225 F-actin monooxygenase
–
a_(2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP+ <=> an_(R)-2-alkyl-3-oxoalkanoate + NADPH + H+ 1.1.1.412 2-alkyl-3-oxoalkanoate reductase
–
M
a_(3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP+ <=> a_(3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + NADPH + H+ 1.1.1.413 A-factor type gamma-butyrolactone 1'-reductase (1S-forming)
–
biphenyl + NADPH + O2 <=> cis-2,3-dihydro-2,3-dihydroxybiphenyl + NADP+ 1.14.12.18 biphenyl 2,3-dioxygenase
1.14.12.22 carbazole 1,9a-dioxygenase
–
–
K
acyldihydroxyacetone_phosphate + NADPH <=> lysophosphatidic_acid + NADP+ 1.1.1.101 acylglycerone-phosphate reductase
–
K
5beta-Pregnan-3alpha-ol-20-one + NADP+ <=> 5beta-pregnane-3,20-dione + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
K
5beta-androstane-3,17-dione + NADPH <=> 5beta-androstane-3alpha-ol-17-one + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
–
–
K
L-galactopyranose + NADP+ <=> L-galactono-1,5-lactone + NADPH + H+ 1.1.1
1.1.1.116 D-arabinose 1-dehydrogenase (NAD+)
1.1.1.B35
–
–
–
MK
dTDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ <=> dTDP-L-rhamnose + NADP+ 1.1.1
1.1.1.133 dTDP-4-dehydrorhamnose reductase
–
–
K
androst-4-ene-3,11,17-trione + NADPH <=> 11beta-hydroxyandrost-4-ene-3,17-dione + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
K
progesterone + NADPH <=> 20alpha-hydroxyprogesterone + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.189 prostaglandin-E2 9-reductase
1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
–
–
–
–
–
–
K
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADPH + H+ <=> tetrahydrobiopterin + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
K
nerol + NADP+ <=> neral + NADPH 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.216 farnesol dehydrogenase (NADP+)
1.1.1.324 8-hydroxygeraniol dehydrogenase
–
–
–
K
1,2-propanediol + NADP+ <=> lactaldehyde + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.55 lactaldehyde reductase (NADPH)
–
–
–
–
9-cis-retinol + NADP+ <=> 9-cis-retinal + NADPH 1.1.1
1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.300 NADP-retinol dehydrogenase
1.1.1.315 11-cis-retinol dehydrogenase
–
–
–
–
–
–
–
K
Naphthalene_dihydrodiol + NADP+ <=> 1,2-dihydroxynaphthalene + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
K
5alpha-pregnane-3alpha,20alpha-diol + NADP+ <=> 5alpha-pregnan-20alpha-ol-3-one + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
–
K
5alpha-Pregnan-3alpha,21-diol-20-one + NADP+ <=> 5alpha-pregnane-21-ol-3,20-dione + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
–
K
L-arabitol + NADP+ <=> L-arabinopyranose + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.307 D-xylose reductase
–
–
–
MK
D-glucose + NADPH <=> sorbitol + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
K
galactitol + NADP+ <=> D-galactose + NADPH + H+ 1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
MK
phenylpyruvate + NADPH <=> D-phenyllactate + NADP+ 1.1.1.110 aromatic 2-oxoacid reductase
1.1.1.237 hydroxyphenylpyruvate reductase
1.1.1.28 D-lactate dehydrogenase
1.1.1.79 glyoxylate reductase (NADP+)
–
–
–
–
K
androstenediol + NADP+ <=> dehydroepiandrosterone + NADPH 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
K
caffeoyl-CoA + NADPH <=> caffeoyl_aldehyde + CoA + NADP+ 1.2.1.44 cinnamoyl-CoA reductase
–
K
4-carboxy-2-hydroxy-cis,cis-muconate_6-semialdehyde + NADP+ <=> 4-carboxy-2-hydroxy-cis,cis-muconate + NADPH 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
–
5-carboxymethyl-2-hydroxymuconate_semialdehyde + H2O + NADP+ <=> 5-Carboxymethyl-2-hydroxymuconate + NADPH 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
–
–
K
Zymosterol + NADPH <=> 5alpha-cholesta-8-en-3beta-ol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
K
Cholesta-5,7,24-trienol + NADPH + H+ <=> 7-dehydrocholesterol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
K
phenylacetaldehyde + NADP+ + H2O <=> phenylacetate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.39 phenylacetaldehyde dehydrogenase
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
K
5-fluorouracil + NADPH <=> 5-fluoro-5,6-dihydrouracil + NADP+ 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
–
K
3alpha,17alpha,21-trihydroxy-5beta-pregnan-11,20-dione + NADP+ <=> 17alpha,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
K
Betaine_aldehyde + NADP+ + H2O <=> betaine + NADPH 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
K
2-decenoyl-[acyl-carrier_protein] + NADPH <=> decanoyl-[acyl-carrier_protein] + NADP+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
K
testosterone + NADPH + H+ <=> 5beta-dihydrotestosterone + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
K
Geissoschizine + NADP+ <=> 4,21-Dehydrogeissoschizine + NADPH 1.3.1.36 geissoschizine dehydrogenase
–
K
trans-2-hexenoyl-CoA + NADPH <=> hexanoyl-CoA + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.44 trans-2-enoyl-CoA reductase (NAD+)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
–
–
K
2-octenoyl-CoA + NADPH <=> octanoyl-CoA + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
–
K
trans-2-decenoyl-CoA + NADPH <=> decanoyl-CoA + NADP+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
K
11-deoxycorticosterone + NADPH <=> 5alpha-pregnane-21-ol-3,20-dione + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
K
trans-2-dodecenoyl-CoA + NADPH <=> lauroyl-CoA + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
–
–
K
2-tetradecenoyl-CoA + NADPH <=> myristoyl-CoA + NADP+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
K
folate + NADPH <=> tetrahydrofolate + NADP+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
1.5.1.34 6,7-dihydropteridine reductase
–
–
–
K
methylseleninate + NADPH <=> methylselenol + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
K
Kynurenic_acid + NADPH + O2 <=> 7,8-Dihydro-7,8-dihydroxykynurenate + NADP+ 1.14.99.2 kynurenine 7,8-hydroxylase
–
K
NADPH + vitamin_B12 <=> NADP+ + cob(I)alamin + cyanide 1.16.1.6 cyanocobalamin reductase (cyanide-eliminating)
–
K
hydroquinone + O2 + NADPH <=> Hydroxyquinol + NADP+ + H2O 1.14.13
1.14.13.7 phenol 2-monooxygenase (NADPH)
1.14.14.20 phenol 2-monooxygenase (FADH2)
–
–
–
K
3,5-dibromo-4-hydroxybenzonitrile + 2 NADPH + 2 H+ + O2 <=> 2,6-dibromo-p-hydroquinone + cyanide + 2 NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
K
2-Hydroxycyclohexan-1-one + NADPH + O2 <=> 1-Oxa-2-oxo-3-hydroxycycloheptane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
K
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + O2 <=> 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
3,4-dihydroxybenzoate + NADPH + O2 <=> Hydroxyquinol + NADP+ + CO2 1.13.11
1.14.13.64 4-hydroxybenzoate 1-hydroxylase
–
–
K
[Methionine_synthase]-cob(II)alamin + NADPH + S-adenosyl-L-methionine <=> [methionine_synthase]methylcob(I)alamin + S-adenosyl-L-homocysteine + NADP+ 1.16.1.8 [methionine synthase] reductase
–
acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+ <=> palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O 2.3.1
2.3.1.86 fatty-acyl-CoA synthase system
–
–
K
beta-D-glucose_6-phosphate + NADP+ <=> 6-phospho-D-glucono-1,5-lactone + NADPH 1.1.1.363 glucose-6-phosphate dehydrogenase [NAD(P)+]
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
–
–
K
2-acetolactate + NADPH <=> 2,3-dihydroxyisovalerate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
11-Dehydrocorticosterone + NADPH <=> corticosterone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.B40
–
–
K
Prostaglandin_D2 + NADPH + H+ <=> 9alpha,11beta-prostaglandin_F2 + NADP+ 1.1.1.188 prostaglandin-F synthase
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
BK
5alpha-pregnan-20alpha-ol-3-one + NADP+ <=> 5alpha-dihydroprogesterone + NADPH 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
–
K
allopregnanolone + NADPH <=> 5alpha-pregnane-3alpha,20alpha-diol + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
K
1-pyrroline-5-carboxylate + NADP+ + H2O <=> L-glutamate + NADPH 1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
–
K
p-Cresol + NADPH + O2 <=> 4-methylcatechol + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
4-methylnitrosamino-1-(3-pyridyl)-1-butanone + NADPH + H+ <=> 4-methylnitrosamino-1-(3-pyridyl)-1-butanol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
K
1''-hydroxy-2''-oxopropyltetrahydropterin + NADPH <=> tetrahydrobiopterin + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.21 aldose reductase
–
–
K
5-hydroxyconiferaldehyde + NADPH <=> 5-hydroxyconiferyl_alcohol + NADP+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
K
caffeoyl_aldehyde + NADPH <=> caffeoyl_alcohol + NADP+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
K
divinyl_protochlorophyllide_a + NADPH <=> divinyl_chlorophyllide_a + NADP+ 1.3.1.33 protochlorophyllide reductase
–
K
tamoxifen + NADPH + O2 <=> tamoxifen_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
K
5-hydroxyferuloyl-CoA + NADPH + H+ <=> 5-hydroxyconiferaldehyde + CoA + NADP+ 1.2.1.44 cinnamoyl-CoA reductase
–
K
cortisol + NADPH <=> 11beta,17alpha,21-trihydroxy-5beta-pregnane-3,20-dione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
K
(24R)-ergost-4-en-3-one + NADPH + H+ + O2 <=> (22S)-22-hydroxycampest-4-en-3-one + NADP+ + H2O 1.14.13
1.14.99.B1
–
–
K
campesterol + NADPH + H+ + O2 <=> 6-deoxocathasterone + NADP+ + H2O 1.14.13
1.14.99.B1
–
–
K
campesterol + NADPH + H+ + O2 <=> (22S)-22-hydroxycampesterol + NADP+ + H2O 1.14.13
1.14.99.B1
–
–
K
butyryl-[acyl-carrier_protein] + NADP+ <=> trans-but-2-enoyl-[acyl-carrier_protein] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
1-Indanone + NADPH + H+ + O2 <=> dihydrocoumarin + NADP+ + H2O 1.14.12
1.14.13.84 4-hydroxyacetophenone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
–
K
2-indanone + NADPH + H+ + O2 <=> 3-isochromanone + NADP+ + H2O 1.14.12
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
K
phosphonoacetaldehyde + NADPH + H+ <=> 2-hydroxyethylphosphonate + NADP+ 1.1.1.309 phosphonoacetaldehyde reductase (NADH)
1.1.99.B6
–
–
K
Caffeine + O2 + NADPH + H+ <=> theophylline + formaldehyde + NADP+ + H2O 1.13.12
1.14.13.128 7-methylxanthine demethylase
–
–
K
4-coumaryl_acetate + NADPH + H+ <=> chavicol + acetate + NADP+ 1.1.1.318 eugenol synthase
–
K
Theobromine + O2 + NADPH + H+ <=> 3-Methylxanthine + formaldehyde + NADP+ 1.13.12
1.14.13.128 7-methylxanthine demethylase
–
–
K
(S)-3-sulfolactate + NADP+ <=> 3-sulfopyruvate + NADPH + H+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
1.1.1.338 (2R)-3-sulfolactate dehydrogenase (NADP+)
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
–
–
–
3-hydroxystearoyl-CoA + NADP+ <=> 3-oxostearoyl-CoA + NADPH + H+ 1.1.1
1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
–
MK
salicylate + NADPH + H+ + O2 <=> 2,5-Dihydroxybenzoate + NADP+ + H2O 1.14.13.172 salicylate 5-hydroxylase
–
K
D-galacturonate + NADPH + H+ <=> L-galactonate + NADP+ 1.1.1
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.203 uronate dehydrogenase
1.1.1.21 aldose reductase
1.1.1.365 D-galacturonate reductase
–
–
–
–
–
BK
biopterin + NADPH + H+ <=> dihydrobiopterin + NADP+ 1.5.1.33 pteridine reductase
–
K
2 Fe2+ + NADP+ + H+ <=> 2 Fe3+ + NADPH 1.16.1.9 ferric-chelate reductase (NADPH)
–
sitosterol + NADPH + H+ + O2 <=> stigmasterol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
K
ergosta-5-enol + NADPH + H+ + O2 <=> brassicasterol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
K
diacetyl + NADPH + H+ <=> (R)-acetoin + NADP+ 1.1.1.B4
–
m-cresol + NADPH + H+ + O2 <=> 3-methylcatechol + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
K
indole + NADPH + H+ + O2 <=> 3-hydroxyindole + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
1.14.16
–
–
K
1,3,8-Trihydroxynaphthalene + NADPH + H+ <=> vermelone + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
D-galactose + NADP+ <=> D-galactono-1,4-lactone + NADPH + H+ 1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase
–
–
–
–
K
5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate_6-semialdehyde + NADP+ <=> stizolobinate + NADPH + H+ 1.13.11.30 stizolobinate synthase
–
K
a_ketosteroid + O2 + NADPH + H+ <=> sterol_ester + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
–
2-octaprenylphenol + O2 + NADPH + H+ <=> 3-(all-trans-octaprenyl)benzene-1,2-diol + H2O + NADP+ 1.14.13.240 2-polyprenylphenol 6-hydroxylase
–
M
GDP-L-fucose + NADP+ <=> GDP-4-keto-6-L-deoxygalactose + NADPH + H+ 1.1.1.271 GDP-L-fucose synthase
–
M
H+ + S-Glutathionyl-L-cysteine + NADPH <=> L-cysteine + glutathione + NADP+ 1.8.1.10 CoA-glutathione reductase
1.8.1.9 thioredoxin-disulfide reductase
1.8.4.2 protein-disulfide reductase (glutathione)
–
–
–
K
ferricytochrome_b5 + NADPH <=> ferricytochrome_b5 + NADP+ + H+ 1.6.2.5 NADPH---cytochrome-c2 reductase
–
NADPH + L-sorbose_1-phosphate + H+ <=> NADP+ + D-sorbitol_6-phosphate 1.1.1
–
MK
DELTA1-piperidine_6-carboxylate + NADP+ + H2O <=> L-2-aminoadipate + NADPH + H+ 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
–
M
3-Hydroxypimeloyl-[acp]_methyl_ester + NADP+ <=> 3-Ketopimeloyl-[acp]_methyl_ester + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
MK
aminopyrrolnitrin + O2 + NADPH + H+ <=> 3-chloro-4-(3-chloro-2-nitrophenyl)pyrrole + NADP+ + H2O 1.14.13
–
MK
Episterone + NADPH + H+ <=> episterol + NADP+ 1.1.1
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
–
MK
choline + NADP+ <=> Betaine_aldehyde + NADPH + H+ 1.1.1
1.1.1.1 alcohol dehydrogenase
–
–
K
dTDP-L-olivose + NADP+ <=> dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+ 1.1.1
–
MK
dTDP-beta-L-mycarose + NADP+ <=> dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose + NADPH + H+ 1.1.1
–
MK
theophylline + NADPH + O2 + H+ <=> 1-Methylxanthine + NADP+ + formaldehyde + H2O 1.14.13.179 methylxanthine N3-demethylase
–
MK
1-Methylxanthine + NADPH + O2 + H+ <=> xanthine + NADP+ + formaldehyde + H2O 1.14.13.178 methylxanthine N1-demethylase
–
MK
tryptamine + O2 + NADPH <=> N-Hydroxyl-tryptamine + H2O + NADP+ 1.14.13
–
MK
Polysulfide + Sulfide + NADP+ <=> Polysulfide + NADPH + H+ 1.8.1.19 sulfide dehydrogenase
–
UDP-2-acetamido-2,6-dideoxy-beta-L-mannose + NADP+ <=> UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose + NADPH + H+ 1.1.1
–
MK
UDP-N-acetyl-6-deoxy-alpha-D-glucosamine + NADP+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose + NADPH + H+ 1.1.1
–
MK
afzelechin + NADP+ + H2O <=> cis-3,4-leucopelargonidin + NADPH + H+ 1.17.1.3 leucoanthocyanidin reductase
–
MK
aurachin_D + O2 + NADPH + H+ <=> aurachin_C + H2O + NADP+ 1.14.13
–
MK
aurachin_B + O2 + NADPH + H+ <=> Aurachin_B_epoxide + NADP+ + H2O 1.14.13
–
MK
mycinamicin_IV + O2 + NADPH + H+ <=> Mycinamicin_V + H2O + NADP+ 1.14.13
–
MK
Mycinamicin_V + O2 + NADPH + H+ <=> mycinamicin_II + H2O + NADP+ 1.14.13
–
MK
Mycinamicin_VIII + O2 + NADPH + H+ <=> Mycinamicin_VII + H2O + NADP+ 1.14.13
–
MK
mycinamicin_IV + O2 + NADPH + H+ <=> Mycinamicin_I + H2O + NADP+ 1.14.13
–
M
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ + (2S)-ethylmalonyl-CoA <=> tylactone + CoA + CO2 + H2O + NADP+ 2.3.1
–
MK
dTDP-beta-L-4-epi-vancosamine + NADP+ <=> dTDP-L-4-oxovancosamine + NADPH + H+ 1.1.1
–
MK
3-Geranylgeranylindole + O2 + NADPH + H+ <=> 10,11-Epoxy-3-geranylgeranylindole + NADP+ + H2O 1.14.13
–
MK
Emindole_SB + O2 + NADPH + H+ <=> 14,15-Epoxyemindole_SB + NADP+ + H2O 1.14.13
–
MK
4-hydroxy-2,2''-bipyrrole-5-methanol + NADP+ <=> 4-hydroxy-2,2''-bipyrrole-5-carbaldehyde + NADPH + H+ 1.1.1
–
MK
medicarpin + NADPH + H+ <=> 7,2''-dihydroxy-4''-methoxyisoflavan + NADP+ 1.1.1
1.23.1
1.3.1
–
–
–
MK
4-Hydroxyisophthalate + O2 + NADPH + H+ <=> 3,4-dihydroxybenzoate + CO2 + NADP+ + H2O 1.14.13
–
MK
Bacteriochlorophyll_b + NADP+ <=> Geranylgeranyl_bacteriochlorophyllide_b + NADPH + H+ 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase
–
K
norbelladine + NADP+ <=> Norcraugsodine + NADPH + H+ 1.4.1
–
MK
7,8-dihydrofolate + NADP+ <=> folate + NADPH + H+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
–
–
K
5,10-methylenetetrahydromethanopterin + NADP+ <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH 1.5.1
–
MK
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + NADP+ <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH 1.3.1
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
–
MK
(Z)-phenylacetaldoxime + O2 + L-cysteine + NADPH + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + H2O + NADP+ 1.14
–
5alpha-campestan-3-one + NADP+ <=> H+ + (24R)-ergost-4-en-3-one + NADPH 1.3.1
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
–
MK
Dihydrogeranylgeranyl_diphosphate + NADP+ <=> geranylgeranyl_diphosphate + NADPH + H+ 1.3.1
–
M
Tetrahydrogeranylgeranyl_diphosphate + NADP+ <=> Dihydrogeranylgeranyl_diphosphate + NADPH + H+ 1.3.1
–
M
phytyl_diphosphate + NADP+ <=> Tetrahydrogeranylgeranyl_diphosphate + NADPH + H+ 1.3.1
–
M
sinapaldehyde + NADP+ + H2O <=> H+ + Sinapic_acid + NADPH 1.2.1
1.2.1.68 coniferyl-aldehyde dehydrogenase
–
–
MK
H+ + 2-nitrobenzoate + NADPH <=> o-Hydroxylaminobenzoate + NADP+ + H2O 1.7.1
–
MK
H+ + Clavulanate-9-aldehyde + NADPH <=> clavulanic_acid + NADP+ not assigned
 –
MK
H+ + 6-propyl-2,3,4,5-tetrahydropyridine + NADPH <=> Coniine + NADP+ 1.5.1
–
M
CDP-4-dehydro-3,6-dideoxy-D-glucose_epimer + NADPH + H+ <=> CDP-ascarylose + NADP+ 1.1.1
1.1.1.M47
–
–
MK
(-)-limonene + NADPH + H+ + O2 <=> (4S)-limonene-1,2-epoxide + NADP+ + H2O 1.14.13.107 limonene 1,2-monooxygenase
–
MK
(1S,4R)-1-hydroxy-2-oxolimonene + NADPH + H+ + O2 <=> (4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(1R,4S)-1-hydroxy-2-oxolimonene + NADPH + H+ + O2 <=> (4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(1R,4S)-isodihydrocarvone + NADPH + H+ + O2 <=> 4-isopropenyl-7-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(-)-dihydrocarvone + O2 + NADPH + H+ <=> (3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O + NADP+ 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(1R,4S)-isodihydrocarvone + O2 + NADPH + H+ <=> (3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O + NADP+ 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
H+ + 1'-hydroxyversicolorone + NADPH + O2 <=> versiconal_hemiacetal_acetate + NADP+ + H2O not assigned
 –
MK
H+ + versicolorone + NADPH + O2 <=> versiconol_acetate + NADP+ + H2O not assigned
 –
MK
hexanoyl-[acyl-carrier_protein] + NADP+ <=> trans-Hex-2-enoyl-[acp] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
(3R)-3-hydroxyoctanoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxooctanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
MK
octanoyl-[acyl-carrier_protein] + NADP+ <=> 2-octenoyl-[acyl-carrier_protein] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
(3R)-3-hydroxydecanoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxodecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
MK
(3R)-3-hydroxymyristoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxotetradecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
MK
tetradecanoyl-[acyl-carrier_protein] + NADP+ <=> trans-Tetradec-2-enoyl-[acp] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
palmitoyl-[acyl-carrier_protein] + NADP+ <=> trans-Hexadec-2-enoyl-[acp] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
K
stearoyl-CoA + NADP+ <=> trans-2-octadecenoyl-CoA + NADPH + H+ 1.3.1
1.3.1.93 very-long-chain enoyl-CoA reductase
–
–
MK
gallocatechin + NADP+ + H2O <=> 3,4-cis-leucodelphinidin + NADPH + H+ 1.17.1.3 leucoanthocyanidin reductase
–
MK
2-Undecylpyrrole + NADP+ + H2O <=> 4-Keto-2-undecylpyrroline + NADPH + H+ 1.17.1
–
MK
trans-4-hydroxy-L-proline + NADP+ <=> NADPH + L-1-pyrroline-3-hydroxy-5-carboxylate + H+ 1.5.1.2 pyrroline-5-carboxylate reductase
–
K
alpha-tetralone + NADPH + H+ <=> alpha-tetralol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
1.1.1.B57
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
formaldehyde + NADPH <=> methanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.244 methanol dehydrogenase
1.1.1.263 1,5-anhydro-D-fructose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
propionaldehyde + NADPH <=> 1-propanol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.80 isopropanol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
–
–
2-methylbutanal + NADPH <=> 2-methylbutanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
pentanal + NADPH <=> 1-Pentanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
hexanal + NADPH + H+ <=> 1-Hexanol + NADP+ 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
Heptanal + NADPH <=> 1-Heptanol + NADP+ 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
–
–
4-methoxybenzaldehyde + NADPH <=> 4-methoxybenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
octanal + NADPH + H+ <=> 1-Octanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.216 farnesol dehydrogenase (NADP+)
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.6.2.4 NADPH---hemoprotein reductase
–
–
–
–
–
–
–
–
–
–
Pyridine-3-aldehyde + NADPH <=> 3-Pyridylcarbinol + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.265 3-methylbutanal reductase
1.1.1.33 mevaldate reductase (NADPH)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.65 pyridoxine 4-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
D-gluconate + NADPH <=> D-glucose + NADP+ 1.1.1.265 3-methylbutanal reductase
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
–
–
–
Quinine + NADPH + O2 <=> 3-hydroxyquinine + NADP+ + H2O 1.14.14.55 quinine 3-monooxygenase
–
laurate + NADPH + H+ + O2 <=> 12-hydroxydodecanoate + NADP+ + H2O 1.14.14.80 long-chain fatty acid omega-monooxygenase
1.14.15.3 alkane 1-monooxygenase
–
–
progesterone + NADPH + O2 <=> 11-deoxycorticosterone + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
1.14.14.16 steroid 21-monooxygenase
–
–
1-Acenaphthenol + NADP+ <=> 1-Acenaphthenone + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
1.10.1.1 trans-acenaphthene-1,2-diol dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
(S)-indan-1-ol + NADP+ <=> 1-Indanone + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
2-Cyclohexen-1-ol + NADP+ <=> 2-cyclohexen-1-one + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
3-Nitrobenzaldehyde + NADPH <=> 3-Nitrobenzyl_alcohol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
2-nitrobenzaldehyde + NADPH <=> 2-nitrobenzyl_alcohol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.65 pyridoxine 4-dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
diacetyl + NADPH <=> 2,3-Butanediol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.21 aldose reductase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
5beta-Pregnan-3alpha-ol-20-one + NADPH + H+ <=> 5beta-pregnane-3alpha,20alpha-diol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
–
–
Cyclohexanol + NADP+ <=> cyclohexanone + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
–
–
–
2-deoxy-D-glucose + NADP+ <=> 2-deoxy-D-glucono-1,5-lactone + NADPH + H+ 1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.121 aldose 1-dehydrogenase (NAD+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
dTDP-6-deoxy-L-lyxo-4-hexulose + NADPH <=> dTDP-L-rhamnose + NADP+ 1.1.1.133 dTDP-4-dehydrorhamnose reductase
–
Epitestosterone + NADP+ <=> 4-androstene-3,17-dione + NADPH 1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
17alpha-estradiol_3-glucuronide + NADP+ <=> estrone_3-glucuronide + NADPH 1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
–
(5beta,20R)-20-hydroxypregnan-3-one + NADP+ <=> 5beta-pregnane-3,20-dione + NADPH 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
pregn-4-ene-3,20,21-trione + NADPH <=> 11-deoxycorticosterone + NADP+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
1,2-propanediol + NADP+ <=> Hydroxyacetone + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
–
2,3-Butanediol + NADP+ <=> acetoin + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.162 erythrulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.4 (R,R)-butanediol dehydrogenase
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
chenodeoxycholic_acid + NADP+ <=> 7-ketolithocholic_acid + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.159 7alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
Methyl_pyruvate + NADPH <=> 2-Methyllactate + NADP+ 1.1.1.162 erythrulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
ethyl_pyruvate + NADPH <=> ethyl_lactate + NADP+ 1.1.1.162 erythrulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
citronellol + NADP+ <=> citronellal + NADPH 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.216 farnesol dehydrogenase (NADP+)
–
–
4-Nitroacetophenone + NADPH <=> 1-(4-nitrophenyl)ethanol + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
–
–
–
–
–
–
4-methylbenzaldehyde + NADPH <=> 4-methylbenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
3-methylbenzaldehyde + NADPH <=> 3-methylbenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
D-Lactaldehyde + NADPH + H+ <=> 1,2-propanediol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
4-carboxybenzaldehyde + NADPH <=> 4-carboxybenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
4-cyanobenzaldehyde + NADPH <=> 4-cyanobenzylalcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.33 mevaldate reductase (NADPH)
–
–
–
3-Formyl-benzonitrile + NADPH <=> 3-cyanobenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
4-methylbenzaldehyde + NADPH <=> Toluene + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
4-Fluorobenzaldehyde + NADPH + H+ <=> 4-fluorobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
3-Fluorobenzaldehyde + NADPH + H+ <=> 3-fluorobenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
4-Chlorobenzaldehyde + NADPH + H+ <=> 4-Chlorobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
3-Chlorobenzaldehyde + NADPH + H+ <=> 3-Chlorobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
p-hydroxyphenylglycolaldehyde + NADPH <=> 4-(2-hydroxyethyl)phenol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
4-hydroxyphenylacetaldehyde + NADPH + H+ <=> 4-(2-hydroxyethyl)phenol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
3-Methoxybenzaldehyde + NADPH + H+ <=> 3-anisyl_alcohol + NADP+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
–
–
–
Pyridine-4-aldehyde + NADPH <=> 4-pyridinemethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.65 pyridoxine 4-dehydrogenase
–
–
–
–
–
2-butanol + NADP+ <=> 2-butanone + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.4 (R,R)-butanediol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.80 isopropanol dehydrogenase (NADP+)
–
–
–
–
–
–
2-Pentanol + NADP+ <=> 2-Pentanone + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.80 isopropanol dehydrogenase (NADP+)
–
–
–
–
–
hexadecanol + NADP+ <=> hexadecanal + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
1.6.2.4 NADPH---hemoprotein reductase
–
–
octadecanal + NADPH + H+ <=> octadecanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
decanal + NADPH + H+ <=> Decanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.216 farnesol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
dodecanal + NADPH + H+ <=> Dodecanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
13-cis-retinal + NADPH <=> 13-cis-retinol + NADP+ 1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.300 NADP-retinol dehydrogenase
–
–
–
pyruvate + NADPH <=> Lactate + NADP+ 1.1.1.110 aromatic 2-oxoacid reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
1.1.1.28 D-lactate dehydrogenase
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
–
–
–
–
–
acetyl-CoA + NADPH <=> acetaldehyde + CoA + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.2.1.10 acetaldehyde dehydrogenase (acetylating)
1.2.1.87 propanal dehydrogenase (CoA-propanoylating)
–
–
–
Salicylaldehyde + NADPH <=> salicyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
cis-benzene_dihydrodiol + NADP+ <=> catechol + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
5beta-pregnane-3alpha,20alpha-diol + NADP+ <=> 5beta-pregnan-20alpha-ol-3-one + NADPH 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
5beta-androstane-3alpha,17beta-diol + NADP+ <=> 5beta-androstane-3alpha,17beta-diol + NADPH 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
–
–
–
acenaphthenequinone + NADPH <=> acenaphthenehydroquinone + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
5alpha-androstane-3alpha,17beta-diol + NADP+ <=> androsterone + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
–
D-erythrose + NADPH <=> erythritol + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.21 aldose reductase
1.1.1.307 D-xylose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
D-ribose + NADPH <=> ribitol + NADP+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
L-Xylose + NADPH <=> xylitol + NADP+ 1.1.1.21 aldose reductase
–
D-mannose + NADPH <=> D-mannitol + NADP+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.289 sorbose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
D-arabinose + NADPH <=> D-arabitol + NADP+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.19 glucuronate reductase
1.1.1.21 aldose reductase
1.1.1.307 D-xylose reductase
–
–
–
–
Dihydrocodeine + NADP+ <=> dihydrocodeinone + NADPH 1.1.1.218 morphine 6-dehydrogenase
–
cyclohexene-2-ol + NADP+ <=> 2-cyclohexen-1-one + NADPH 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.218 morphine 6-dehydrogenase
–
–
pyruvate + NADPH + H+ <=> L-lactate + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.27 L-lactate dehydrogenase
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
–
–
–
–
5alpha-androstane-3,17-dione + NADPH <=> epiandrosterone + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
–
–
–
5alpha-dihydrotestosterone + NADP+ <=> 5alpha-androstane-3,17-dione + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
5alpha-Androstane-3beta,17beta-diol + NADP+ <=> epiandrosterone + NADPH 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
5beta-androstane-3alpha,17beta-diol + NADP+ <=> 5beta-androstane-3,17-dione + NADPH 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
4-Hydroxybenzyl_alcohol + NADP+ <=> 4-hydroxybenzaldehyde + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
phosphite + H2O + NADP+ <=> phosphate + NADPH + H+ 1.20.1.1 phosphonate dehydrogenase
–
D-glyceraldehyde_3-phosphate + arsenate + NADP+ <=> 3-phospho-D-glyceroyl_arsenate + NADPH 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)
1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
–
–
–
3-deoxyglucosone + NADP+ + H2O <=> 2-dehydro-3-deoxy-D-gluconate + NADPH + H+ 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
2 ferricytochrome_c + NADPH <=> 2 ferricytochrome_c + NADP+ + H+ 1.16.1.8 [methionine synthase] reductase
1.18.1.2 ferredoxin---NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
1.6.2.4 NADPH---hemoprotein reductase
1.6.2.6 leghemoglobin reductase
1.7.1.3 nitrate reductase (NADPH)
1.8.1.2 assimilatory sulfite reductase (NADPH)
–
–
–
–
–
–
–
1,4-Naphthoquinone + NADPH <=> NADP+ + 1,4-naphthoquinol 1.1.1.328 nicotine blue oxidoreductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
1.7.1.6 azobenzene reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
1,2-naphthoquinone + NADPH <=> NADP+ + 1,2-dihydroxynaphthalene 1.1.1.2 alcohol dehydrogenase (NADP+)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
–
–
–
–
2-Chlorobenzaldehyde + NADPH + H+ <=> 2-chlorobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
2 ferricyanide + NADPH <=> 2 ferrocyanide + NADP+ + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.12.1.2 hydrogen dehydrogenase
1.14.13.39 nitric-oxide synthase (NADPH)
1.14.14.1 unspecific monooxygenase
1.16.1.7 ferric-chelate reductase (NADH)
1.16.1.9 ferric-chelate reductase (NADPH)
1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.6 adrenodoxin-NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
1.4.1.13 glutamate synthase (NADPH)
1.6.2.2 cytochrome-b5 reductase
1.6.2.4 NADPH---hemoprotein reductase
1.6.2.5 NADPH---cytochrome-c2 reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.4 monodehydroascorbate reductase (NADH)
1.7.1.3 nitrate reductase (NADPH)
1.7.1.6 azobenzene reductase
1.8.1.7 glutathione-disulfide reductase
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
crotonaldehyde + NADPH <=> 2-Buten-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
Nonanal + NADPH <=> 1-nonanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.21 aldose reductase
1.1.1.300 NADP-retinol dehydrogenase
1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
ethyl_2-chloro-3-oxobutanoate + NADPH + H+ <=> ethyl_2-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
ethyl_acetoacetate + NADPH <=> ethyl_3-hydroxybutanoate + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
–
–
prostaglandin_E2 + NADP+ <=> 15-ketoprostaglandin_E2 + NADPH + H+ 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+)
1.1.1.189 prostaglandin-E2 9-reductase
1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
–
–
–
–
–
4-methylcyclohexanone + NADPH <=> 4-methylcyclohexanol + NADP+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
–
–
3-methylcyclohexanone + NADPH <=> 3-Methylcyclohexanol + NADP+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
–
–
4-nitrobenzaldehyde + NADP+ <=> 4-nitrobenzoate + NADPH 1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
–
methyl_p-tolyl_sulfide + NADPH + O2 <=> methyl_4-tolyl_sulfoxide + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
–
formaldehyde + NADP+ + H2O <=> formate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
Nonanal + NADP+ + H2O <=> Nonanoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
dodecanal + NADP+ + H2O <=> laurate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
glycolaldehyde + NADP+ + H2O <=> glycolate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.21 glycolaldehyde dehydrogenase
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+)
–
–
–
–
–
–
–
testosterone + NADPH + H+ <=> 4-androsten-3alpha,17beta-diol + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
5beta-dihydrotestosterone + NADPH <=> 5beta-androstane-3beta,17beta-diol + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
–
–
5beta-androstane-3,17-dione + NADPH <=> 5beta-androstan-3beta-ol-17-one + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
–
–
testosterone + NADPH + H+ <=> 4-Androsten-3beta,17beta-diol + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
–
–
4-androstene-3,17-dione + NADPH + H+ <=> dehydroepiandrosterone + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
menadione + NADPH <=> menadiol + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.328 nicotine blue oxidoreductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.4.1.13 glutamate synthase (NADPH)
1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H]
1.6.2.4 NADPH---hemoprotein reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.12 demethylphylloquinone reductase
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.8.1.15 mycothione reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
3-bromobenzaldehyde + NADPH + H+ <=> 3-bromobenzyl_alcohol + NADP+ 1.1.1.21 aldose reductase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
4-bromobenzaldehyde + NADPH + H+ <=> 4-bromobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
Crotonyl-N-acetyl-cysteamine + NADPH <=> Butyryl-N-acetyl-cysteamine + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
–
–
–
trans-2-octenoyl-N-acetylcysteamine + NADPH <=> octanoyl-N-acetylcysteamine + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
–
–
–
dihydrodipicolinate + NADPH <=> tetrahydrodipicolinate + NADP+ 1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase
–
crotonaldehyde + NADPH <=> Butyraldehyde + NADP+ 1.3.1.27 2-hexadecenal reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
–
–
–
trans-2-hexenal + NADPH <=> hexanal + NADP+ 1.3.1.27 2-hexadecenal reductase
1.3.1.31 2-enoate reductase
1.3.1.42 12-oxophytodienoate reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
1.6.99.1 NADPH dehydrogenase
–
–
–
–
–
–
–
3-penten-2-one + NADPH <=> 2-Pentanone + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
–
–
–
10-formyl-5,8-dideazafolate + NADP+ + H2O <=> 5,8-Dideazafolate + CO2 + NADPH + H+ 1.5.1.6 formyltetrahydrofolate dehydrogenase
–
NADPH + 2,6-dichlorophenolindophenol <=> NADP+ + reduced_2,6-dichlorophenolindophenol 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.328 nicotine blue oxidoreductase
1.12.1.2 hydrogen dehydrogenase
1.17.1.4 xanthine dehydrogenase
1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.3 ferredoxin---NAD+ reductase
1.18.1.6 adrenodoxin-NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
1.5.1.30 flavin reductase (NADPH)
1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
1.6.2.4 NADPH---hemoprotein reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.7.1.6 azobenzene reductase
1.8.1.4 dihydrolipoyl dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
NADPH + thio-NAD+ + H+ <=> NADP+ + thio-NADH + H+ 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
7.1.1.1 proton-translocating NAD(P)+ transhydrogenase
–
–
–
–
NADPH + H+ + ubiquinone <=> NADP+ + ubiquinol 1.1.1.184 carbonyl reductase (NADPH)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.11 NADH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.8.1.4 dihydrolipoyl dehydrogenase
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
–
–
–
–
–
–
NADPH + H+ + duroquinone <=> NADP+ + durohydroquinone 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
NADPH + 9,10-phenanthrenequinone <=> NADP+ + 9,10-phenanthrenequinol 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.263 1,5-anhydro-D-fructose reductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.7.1.6 azobenzene reductase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
5-hydroxy-1,4-naphthoquinone + NADPH <=> 5-hydroxy-1,4-naphthoquinol + NADP+ 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.8.1.15 mycothione reductase
1.8.1.8 protein-disulfide reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
5,5''-dithiobis(2-nitrobenzoic_acid) + NADPH <=> 5-thio-2-nitrobenzoate + NADP+ 1.8.1.15 mycothione reductase
1.8.1.7 glutathione-disulfide reductase
1.8.1.8 protein-disulfide reductase
1.8.1.9 thioredoxin-disulfide reductase
1.8.1.B1
–
–
–
–
–
Butyraldehyde + NADP+ + H2O <=> Butyrate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
–
–
–
–
pentanal + NADP+ <=> pentanoate + NADPH 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
–
–
–
–
–
Isovaleraldehyde + NADP+ + H2O <=> Isovalerate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
–
hexanal + NADP+ <=> hexanoate + NADPH 1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
–
–
–
Heptanal + NADP+ <=> Heptanoate + NADPH 1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
–
–
–
–
–
octanal + NADP+ + H2O <=> Octanoate + NADPH + H+ 1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
–
–
decanal + NADP+ <=> Decanoate + NADPH 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
–
Undecanal + NADP+ <=> Undecanoate + NADPH 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
squalene + NADPH + O2 <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + NADP+ + H2O 1.14.14.17 squalene monooxygenase
–
testosterone + NADPH + O2 <=> 6beta-hydroxytestosterone + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
1.14.14.25 cholesterol 24-hydroxylase
1.14.14.55 quinine 3-monooxygenase
1.14.14.57 taurochenodeoxycholate 6alpha-hydroxylase
1.14.99.4 progesterone monooxygenase
–
–
–
–
–
tabersonine + NADPH + H+ + O2 <=> 16-hydroxytabersonine + NADP+ + H2O 1.14.14.103 tabersonine 16-hydroxylase
–
Pentachlorophenol + NADPH + O2 <=> tetrachlorohydroquinone + NADP+ + Cl- 1.14.13.50 pentachlorophenol monooxygenase
–
thioanisole + NADPH + H+ + O2 <=> (R)-methyl_phenyl_sulfoxide + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
–
–
25-hydroxyvitamin_D3 + NADPH + O2 <=> 1alpha,25-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
1.14.15.15 cholestanetriol 26-monooxygenase
1.14.15.18 calcidiol 1-monooxygenase
–
–
–
B
quinonoid_2-amino-4-hydroxy-6,7-dimethyldihydropteridine + NADPH <=> 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
hypoxanthine + NADP+ + H2O <=> xanthine + NADPH 1.17.1.4 xanthine dehydrogenase
–
acetophenone + NADPH + H+ + O2 <=> phenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-hydroxypropiophenone + NADPH + H+ + O2 <=> 4-Hydroxyhydratropate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-methylacetophenone + NADPH + H+ + O2 <=> p-tolyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-methoxyacetophenone + NADPH + H+ + O2 <=> 4-methoxy_phenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-fluoroacetophenone + NADPH + H+ + O2 <=> 4-Fluorophenylacetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-hydroxy-3-methylacetophenone + NADPH + H+ + O2 <=> 4-hydroxy-3-methylphenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
2-hydroxyacetophenone + NADPH + H+ + O2 <=> 2-hydroxyphenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
3-hydroxyacetophenone + NADPH + H+ + O2 <=> 3-hydroxyphenylacetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
benzaldehyde + NADPH + H+ + O2 <=> phenyl_formate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
propiophenone + NADPH + H+ + O2 <=> phenylpropionate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
butyrophenone + NADPH + H+ + O2 <=> phenyl_butyrate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
isobutyrophenone + NADPH + H+ + O2 <=> phenyl_isobutyrate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
5beta-androstane-3alpha,17beta-diol + NADP+ <=> 5beta-androstane-3alpha-ol-17-one + NADPH 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
heme + 2 NADPH + 2 H+ + 2 O2 <=> Biliverdin + Fe2+ + CO + 2 NADP+ + H2O 1.14.14.18 heme oxygenase (biliverdin-producing)
–
7beta-hydroxycholesterol + NADP+ <=> 7-oxocholesterol + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
1.1.1.B40
–
–
–
ethyl_4-chloro-3-oxobutanoate + NADPH + H+ <=> ethyl_(S)-4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.B3
1.1.1.B51
–
–
–
–
3-methyl-2-oxopentanoate + NADPH <=> 2-hydroxy-3-methylpentanoate + NADP+ 1.1.1.169 2-dehydropantoate 2-reductase
–
7alpha-hydroxycholesterol + NADP+ <=> 7-oxocholesterol + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
acetophenone + NADPH <=> (R)-1-phenylethanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Chloroacetaldehyde + NADP+ + H2O <=> Chloroacetate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
–
D-ribulose + NADPH <=> ribitol + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+)
–
–
D-threose + NADPH <=> D-threitol + NADP+ 1.1.1.10 L-xylulose reductase
–
glutathione-4-oxonon-2-enal + NADPH <=> glutathione-4-oxononanal + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
NADP+ + H2O <=> 2'-phospho-ADP-ribose + nicotinamide 3.2.2.5 NAD+ glycohydrolase
3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
–
–
pyridoxal + NADP+ <=> 4-Pyridoxolactone + NADPH + H+ 1.1.1.107 pyridoxal 4-dehydrogenase
–
tibolone + NADPH <=> 3alpha-tibolone + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
tibolone + NADPH <=> 3beta-hydroxytibolone + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
trans-2-nonenal + NADPH + H+ <=> trans-2-nonen-1-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
7alpha-hydroxy-4-cholesten-3-one + NADPH + H+ + O2 <=> 7alpha,12alpha-dihydroxy-4-cholesten-3-one + NADP+ + H2O 1.14.18.8 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
–
2,5-bis(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione + NADPH <=> 2,5-diaziridinyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.8.1.9 thioredoxin-disulfide reductase
–
–
2,5-bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione + NADPH <=> 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.8.1.9 thioredoxin-disulfide reductase
–
–
2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone + NADPH <=> 2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.8.1.9 thioredoxin-disulfide reductase
–
–
2,6-dimethyl-1,4-benzoquinone + NADPH <=> 2,6-dimethyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.8.1.15 mycothione reductase
1.8.1.8 protein-disulfide reductase
–
–
–
–
2-dodecanone + NADPH + O2 <=> nonyl_acetate + methyl_decanoate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
cytochrome_c + NADPH <=> ferricytochrome_c + NADP+ 1.1.1.404 tetrachlorobenzoquinone reductase
1.14.14.1 unspecific monooxygenase
1.18.1.2 ferredoxin---NADP+ reductase
1.6.2.2 cytochrome-b5 reductase
1.6.2.4 NADPH---hemoprotein reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
2,5-dibromo-3-methyl-6-isopropylbenzoquinone + NADPH <=> 2,5-dibromo-3-methyl-6-isopropyl-4-benzoquinol + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
1.6.5.10 NADPH dehydrogenase (quinone)
–
–
fenthion + NADPH + O2 <=> (rac)_fenthion_sulfoxide + NADP+ 1.14.13.8 flavin-containing monooxygenase
1.14.14.1 unspecific monooxygenase
–
–
NADPH + H+ + 2,3-dimethoxy-5-methyl-1,4-benzoquinone <=> NADP+ + reduced_coenzyme_Q0 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
–
reduced_ferredoxin_I + NADP+ <=> oxidized_ferredoxin_I + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
4-oxonon-2-enal + NADPH + H+ <=> 1-hydroxynon-2-en-4-one + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
4-oxonon-2-enal + NADPH + H+ <=> 4-hydroxy-2-nonenal + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
4-oxonon-2-enal + NADPH + H+ <=> 4-oxononanal + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
daunorubicin + NADPH + H+ <=> 13-dihydrodaunorubicin + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
–
–
–
doxorubicin + NADPH + H+ <=> doxorubicinol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
glutathione-4-oxonon-2-enal + NADPH + H+ <=> glutathione-4-hydroxynon-2-enal + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
androstanedione + NADPH <=> 5alpha-androstane-3-one-17alpha-ol + NADP+ 1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
–
androsterone + NADPH <=> 5alpha-androstane-3alpha,17alpha-diol + NADP+ 1.1.1.148 estradiol 17alpha-dehydrogenase
–
hydroxycobalamin + NADPH + H+ <=> Cobalamin + NADP+ 1.16.1.3 aquacobalamin reductase
1.16.1.5 aquacobalamin reductase (NADPH)
–
–
cholesterol + NADPH + O2 <=> (24S)-24-hydroxycholesterol + NADP+ + H2O 1.14.14.25 cholesterol 24-hydroxylase
–
L-methionine + NADPH + O2 <=> methionine_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2,4,6-trinitrotoluene + NADPH_+ <=> 2,4,6-trinitrotoluene + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.99.1 NADPH dehydrogenase
–
–
2-acetylpyridine + NADPH <=> (S)-1-(2-pyridyl)ethanol + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
3-hydroxy-4-methylbenzoate + NADPH + O2 <=> 4-Methylgentisate + NADP+ + H2O 1.14.13.24 3-hydroxybenzoate 6-monooxygenase
–
4-hydroxy-2-nonenal + NADP+ + H2O <=> (2E)-4-hydroxynon-2-enoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
Benzydamine + NADPH + O2 <=> benzydamine_N-oxide + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
ethylenethiourea + NADPH + O2 <=> ethylenethiourea_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
NADPH + H+ + duroquinone <=> NADP+ + duroquinol 1.1.1.188 prostaglandin-F synthase
1.1.1.328 nicotine blue oxidoreductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
–
–
–
–
S-Benzyl-L-cysteine + NADPH + O2 <=> petiveriin + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
trans-2-hexenal + NADP+ + H2O <=> trans-2-hexenoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
trans-2-nonenal + NADP+ + H2O <=> (2E)-non-2-enoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
trans-2-octenal + NADP+ + H2O <=> (2E)-oct-2-enoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
(1R,4S)-1-hydroxy-2-oxolimonene + NADPH + H+ + O2 <=> 3-isopropenyl-6-oxoheptanoate + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
(1S,4R)-1-hydroxy-2-oxolimonene + NADPH + H+ + O2 <=> 3-isopropenyl-6-oxoheptanoate + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
2-trans,4-trans-decadienoyl-CoA + NADPH <=> trans-3-decenoyl-CoA + NADP+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
4-benzoylpyridine + NADPH <=> phenyl-4-pyridylmethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
dehydroepiandrosterone + NADP+ <=> 5-androstene-3,17-dione + NADPH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
–
coenzyme_Q10 + NADPH <=> ubiquinol + NADP+ 1.1.1.188 prostaglandin-F synthase
1.8.1.4 dihydrolipoyl dehydrogenase
–
–
benzoyl-CoA + NADPH + H+ + O2 <=> 2,3-dihydro-2,3-dihydroxybenzoyl-CoA + NADP+ 1.14.13.208 benzoyl-CoA 2,3-epoxidase
–
vitamin_D3 + NADPH + O2 <=> 25-hydroxyvitamin_D3 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
1.14.15.15 cholestanetriol 26-monooxygenase
1.14.15.18 calcidiol 1-monooxygenase
–
–
–
B
2 Plumbagin + NADPH + H+ <=> Plumbagin + NADP+ 1.6.5.5 NADPH:quinone reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
NADPH + iodonitrotetrazolium_chloride <=> NADP+ + reduced_iodonitrotetrazolium_chloride 1.18.1.2 ferredoxin---NADP+ reductase
1.4.1.13 glutamate synthase (NADPH)
–
–
Methimazole + NADPH + H+ + O2 <=> methimazole_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2-Methylpentanal + NADPH + H+ <=> 2-Methyl-1-pentanol + NADP+ 1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
L-gulonate + NADP+ <=> 3-dehydro-L-gulonate + NADPH + H+ 1.1.1.45 L-gulonate 3-dehydrogenase
–
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> secalciferol + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
1alpha-hydroxyvitamin_D2 + O2 + NADPH + H+ <=> 1alpha,25-dihydroxyvitamin_D2 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
1.14.15.15 cholestanetriol 26-monooxygenase
–
–
H2O + O2 + NADPH + H+ <=> 1alpha,25-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
1.14.15.15 cholestanetriol 26-monooxygenase
–
–
bufuralol + O2 + NADPH + H+ <=> 1''-hydroxybufuralol + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
1.14.14.24 vitamin D 25-hydroxylase
1.14.14.25 cholesterol 24-hydroxylase
–
–
–
vitamin_D2 + O2 + NADPH + H+ <=> 25-hydroxyvitamin_D2 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
–
D-galactose + NADP+ + H2O <=> D-galactonate + NADPH + 2 H+ 1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
–
–
(R)-2-butanol + NADP+ <=> 2-butanone + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
–
androstanediol + NADP+ <=> 5alpha-dihydrotestosterone + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
–
2-cyclohexen-1-one + NADPH + H+ <=> cyclohexanone + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
1.6.99.1 NADPH dehydrogenase
–
–
corticosterone + NADPH + H+ <=> 5alpha-dihydrocorticosterone + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
1alpha,25-dihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,24,25-trihydroxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
(S)-1-phenyl-2-propanol + NADP+ <=> phenylacetone + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
benzylacetone + NADPH + H+ <=> (S)-4-phenylbutan-2-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
(+)-borneol + NADP+ <=> (+)-Camphor + NADPH + H+ 1.1.1.198 (+)-borneol dehydrogenase
–
L-arabinose + NADP+ <=> L-arabino-1,5-lactone + NADPH + H+ 1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
picolinaldehyde + NADPH + H+ <=> 2-hydroxymethylpyridine + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.65 pyridoxine 4-dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
L-cystine + NADPH + H+ <=> 2 L-cysteine + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
(S)-N-methylcoclaurine + NADPH + H+ + O2 <=> (S)-3''-hydroxy-N-methylcoclaurine + NADP+ + H2O 1.14.13.71 N-methylcoclaurine 3'-monooxygenase
1.14.14.102 N-methylcoclaurine 3'-monooxygenase
–
–
Pentane-2,4-dione + NADPH + H+ <=> 4-hydroxypentan-2-one + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
ethyl_2-oxobutanoate + NADPH + H+ <=> ethyl-2-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
methyl_4-chloro-3-oxobutanoate + NADPH + H+ <=> methyl_4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Camphorquinone + NADPH + H+ <=> 1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
D-galactose_6-phosphate + NADP+ <=> 6-phospho-D-galactono-1,5-lactone + NADPH + H+ 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
–
–
fenthion + NADPH + H+ + O2 <=> fenthion-oxon + sulfur + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
L-tyrosine + O2 + NADPH + H+ <=> N-hydroxy-L-tyrosine + NADP+ + H2O 1.14.14.36 tyrosine N-monooxygenase
–
4-N-trimethylaminobutyraldehyde + NADP+ + H2O <=> gamma-butyrobetaine + NADPH + H+ 1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase
–
pterin + NADPH + H+ <=> Tetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
butyryl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ <=> palmitate + (n+1)_CoA + n CO2 + 2n NADP+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
octanoyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ <=> palmitate + (n+1)_CoA + n CO2 + 2n NADP+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
2-ethylbenzoate + NADP+ <=> 2-carboxybenzaldehyde + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.co
–
–
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 6-hydroxymellein + CoA + CO2 + NADP+ + H2O 2.3.1
–
M
NADPH + L-xylo-3-hexulose + H+ <=> D-sorbitol + NADP+ 1.1.1
–
M
aflatoxin_B1 + O2 + NADPH + H+ <=> Aflatoxin_B1-exo-8,9-epoxide + H2O + NADP+ 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
aflatoxin_B1 + O2 + NADPH + H+ <=> Aflatoxin_Q1 + H2O + NADP+ 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
aflatoxin_B1 + O2 + NADPH + H+ <=> Aflatoxin_M1 + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
K
cyclophosphamide + NADPH + H+ + O2 <=> 4-Hydroxycyclophosphamide + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
5alpha-androstane-3,17-dione + NADP+ <=> 4-androstene-3,17-dione + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
K
(E,Z)-indolyl-3-acetaldoxime + L-cysteine + NADPH + O2 + H+ <=> S-(Indolylmethylthiohydroximoyl)-L-cysteine + NADP+ + 2 H2O 1.14.14.43 (methylsulfanyl)alkanaldoxime N-monooxygenase
1.14.14.45 aromatic aldoxime N-monooxygenase
–
–
K
17beta-estradiol + H+ + O2 + NADPH <=> 2-hydroxyestradiol + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
K
tetrahydrocortisol + NADP+ <=> 11beta,17alpha,21-trihydroxy-5beta-pregnane-3,20-dione + NADPH + H+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
K
Tetrahydrocorticosterone + NADP+ <=> 5beta-dihydrocorticosterone + NADPH + H+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
K
retinoic_acid + NADPH + H+ + O2 <=> all-trans-4-Hydroxyretinoic_acid + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
carbamazepine + NADPH + H+ + O2 <=> carbamazepine-10,11-epoxide + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
1.14.14.55 quinine 3-monooxygenase
–
–
–
K
benzo(a)pyrene-7,8-diol + NADPH + O2 + H+ <=> Benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
(R)-2,3-dihydroxy-3-methylbutanoate + NADP+ <=> 3-hydroxy-3-methyl-2-oxobutanoic_acid + NADPH + H+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
K
NADPH + 2 Ferrocytochrome <=> NADP+ + 2 Ferrocytochrome + H+ 1.6.2.4 NADPH---hemoprotein reductase
–
amino_acid + H2O + NADP+ <=> a_2-oxo_carboxylate + NH3 + NADPH + H+ 1.4.1.1 alanine dehydrogenase
1.4.1.10 glycine dehydrogenase
1.4.1.12 2,4-diaminopentanoate dehydrogenase
1.4.1.15 lysine dehydrogenase
1.4.1.19 tryptophan dehydrogenase
1.4.1.2 glutamate dehydrogenase
1.4.1.20 phenylalanine dehydrogenase
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
1.4.1.5 L-amino-acid dehydrogenase
1.4.1.7 serine 2-dehydrogenase
1.4.1.8 valine dehydrogenase (NADP+)
1.4.1.9 leucine dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
D-glucose + NADP+ <=> D-glucono-1,4-lactone + NADPH + H+ 1.1.1.119 glucose 1-dehydrogenase (NADP+)
–
malonyl-CoA + NADPH + H+ <=> 3-oxopropanoyl-CoA + NADP+ + H2O not assigned
 –
K
an_L-amino_acid + O2 + NADPH <=> N-Hydroxy-amino_acid + NADP+ + H2O 1.14.13
–
(R)-5,6-Dihydrothymine + NADP+ <=> thymine + NADPH + H+ 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
K
cholesterol + O2 + NADPH + H+ <=> 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + NADP+ + H2O 1.14.13
–
cholesterol + O2 + NADPH + H+ <=> 5,6beta-epoxy-5beta-cholestan-3beta-ol + NADP+ + H2O 1.14.13
–
2-oxoadipate + NH3 + NADP+ <=> 2-aminomuconate + NADPH + H+ + H2O 1.5.1
–
K
stearoyl-CoA + malonyl-CoA + 2 NADPH + 2 H+ <=> arachidoyl-CoA + CO2 + 2 NADP+ + CoA + H2O not assigned
 –
estrone + H+ + O2 + NADPH <=> 2-hydroxyestrone + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
K
estrone + H+ + O2 + NADPH <=> 16alpha-hydroxyestrone + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
homogentisate + O2 + NADPH <=> 2,5-dihydroxybenzaldehyde + CO2 + NADP+ + H+ + H2O 4.1.1
–
K
4-hydroxyphenylacetaldehyde + NADP+ + H2O <=> 4-hydroxyphenylacetate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
K
R-CN + O2 + NADPH + H+ <=> (S)-Hydroxynitrile + NADP+ + H2O 1.14.13
–
medicarpin + NADP+ + H2O <=> vestitone + NADPH + H+ not assigned
 –
dTDP-glucose + 2 NADP+ + H2O <=> dTDP-D-glucuronate + 2 NADPH + 2 H+ 1.1.1
–
17beta-estradiol + H+ + O2 + NADPH <=> estriol + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
K
L-hydroxyproline + NADP+ <=> 4-Oxoproline + NADPH + H+ 1.1.1.104 4-oxoproline reductase
–
K
3,4-dihydroxyphenylacetaldehyde + NADP+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
K
dehydroepiandrosterone + H+ + O2 + NADPH <=> 16alpha-hydroxy-dehydroepiandrosterone + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
Toluene + O2 + NADPH + H+ <=> m-cresol + NADP+ + H2O 1.14.13
–
K
selenium + 3 NADP+ + 3 H2O <=> Selenite + 3 NADPH + 5 H+ 1.8.1.9 thioredoxin-disulfide reductase
–
K
11beta,21-dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADP+ <=> aldosterone + NADPH + H+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
K
5beta-dihydrocorticosterone + NADP+ <=> corticosterone + NADPH + H+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
leukotriene_B4 + NADP+ <=> 12-Keto-leukotriene_B4 + H+ + NADPH not assigned
 –
7alpha-hydroxycholesterol + NADP+ <=> 7alpha-hydroxy-4-cholesten-3-one + NADPH + H+ 1.1.1.181 cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase
–
5alpha-Cholest-7-en-3beta-ol + CO2 + 4 H2O + 3 NADP+ <=> Methostenol + 3 O2 + 3 NADPH + 3 H+ 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.14.18.9 4alpha-methylsterol monooxygenase
–
–
–
alpha-Aminoadipoyl-S-acyl_enzyme + NADPH + H+ <=> (S)-2-amino-6-oxohexanoate + Holo-Lys2 + NADP+ 1.2.1.95 L-2-aminoadipate reductase
–
K
L-1-pyrroline-3-hydroxy-5-carboxylate + NADP+ + 2 H2O <=> L-erythro-4-hydroxyglutamate + NADPH + H+ 1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
–
K
(3R)-3-hydroxypalmitoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxohexadecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
K
24,25-dihydrolanosterol + NADPH <=> 4alpha-Methylcholesta-8-en-3beta-ol + NADP+ not assigned
 –
estriol + NADP+ <=> 16alpha-hydroxyestrone + NADPH + H+ 1.1.1.62 17beta-estradiol 17-dehydrogenase
–
K
D-2,5-diaminohexanoate + H2O + NADP+ <=> 2-Amino-5-oxohexanoate + NH3 + NADPH + H+ 1.4.1.12 2,4-diaminopentanoate dehydrogenase
–
K
5-Cholestene + O2 + NADPH + H+ <=> 5,6beta-Epoxy-5beta-cholestane + NADP+ + H2O 1.14.13
–
5-Cholestene + NADPH + O2 + H+ <=> 5,6alpha-Epoxy-5alpha-cholestane + NADP+ + H2O 1.14.13
–
3alpha,11beta,21-trihydroxy-20-oxo-5beta-pregnan-18-al + NADP+ <=> 11beta,21-dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADPH + H+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
K
Tetrahydrocorticosterone + NADP+ <=> 3alpha,21-dihydroxy-5beta-pregnane-11,20-dione + NADPH + H+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
K
3alpha,21-dihydroxy-5beta-pregnane-11,20-dione + NADP+ <=> 21-hydroxy-5beta-pregnane-3,11,20-trione + NADPH + H+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
K
3,4-dihydroxyphenylglycolaldehyde + NADP+ + H2O <=> 3,4-dihydroxymandelate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
K
3-methoxy-4-hydroxyphenylacetaldehyde + NADP+ + H2O <=> homovanillic_acid + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
K
4-hydroxyphenyl-3-methoxyglycolaldehyde + NADP+ + H2O <=> vanillylmandelic_acid + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
K
5-(3''-Carboxy-3''-oxopropenyl)-4,6-dihydroxypicolinate + NADPH + H+ <=> 5-(3''-Carboxy-3''-oxopropyl)-4,6-dihydroxypicolinate + NADP+ 1.3.1
–
K
5-(2''-Formylethyl)-4,6-dihydroxypicolinate + NADP+ + H2O <=> 5-(2''-Carboxyethyl)-4,6-dihydroxypicolinate + NADPH + H+ 1.2.1
–
K
bithionol + NADP+ <=> 3-oxopropanoyl-CoA + NADPH + H+ 1.1.1
–
K
3''-Phosphoadenylylselenate + NADPH <=> Adenosine_3'',5''-bisphosphate + Selenite + NADP+ + H+ not assigned
 –
(3R)-3-hydroxyhexanoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxohexanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
K
(R)-3-hydroxydodecanoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxododecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
K
2-Hexaprenylphenol + O2 + NADPH <=> 2-Hexaprenyl-6-hydroxyphenol + NADP+ + H2O 1.14.13
–
2-methoxy-6-(all-trans-octaprenyl)phenol + O2 + NADPH <=> 2-octaprenyl-6-methoxy-1,4-benzoquinone + NADP+ + H2O 1.14.13
–
2R,3R-2,3-dihydroxy-3-methylpentanoate + NADP+ <=> (R)-3-hydroxy-3-methyl-2-oxopentanoate + NADPH + H+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
K
Cytochrome_P-450_oxidized_form + NADPH <=> Cytochrome_P-450_reduced_form + NADP+ + H+ 1.6.2.4 NADPH---hemoprotein reductase
–
acyl-CoA + n methylmalonyl-CoA + 2n NADPH + 2n H+ + [acyl-carrier_protein] <=> Multi-methyl-branched_acyl-[acp] + (n+1)_CoA + n CO2 + 2n NADP+ + n H2O 2.3.1.111 mycocerosate synthase
2.3.1.252 mycolipanoate synthase
–
–
6-hydroxyhexanoate + NADP+ <=> 6-oxohexanoate + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
K
pyrogallol + NADP+ + H2O <=> resorcinol + O2 + NADPH + H+ not assigned
 –
4-chlorobiphenyl + O2 + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxy-4''-chlorobiphenyl + NADP+ 1.14.12.18 biphenyl 2,3-dioxygenase
–
K
4-methylbenzaldehyde + NADP+ + H2O <=> 4-Methylbenzoate + NADPH + H+ 1.2.1.28 benzaldehyde dehydrogenase (NAD+)
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
–
–
K
4-Methylbenzoate + O2 + NADPH + H+ <=> cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ 1.14.12
–
K
cis-2,3-Dihydrodiol_1,1,1-Trichloro-2,2-bis(4''-chlorophenyl)ethane + NADP+ <=> 2,3-Dihydroxy_1,1,1-Trichloro-2,2-bis(4''-chlorophenyl)ethane + NADPH + H+ 1.3.1
–
2 1-Indanone + O2 + 2 NADPH + 2 H+ <=> 2 3-hydroxy-1-indanone + 2 NADP+ 1.14.12
–
K
9-fluorenone + O2 + 2 NADPH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NADP+ 1.14.12
–
K
benzoate + NADPH + H+ + O2 <=> (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NADP+ 1.14.12.10 benzoate 1,2-dioxygenase
–
K
2-Methylbenzaldehyde + NADP+ + H2O <=> 2-Methylbenzoate + NADPH + H+ 1.2.1.28 benzaldehyde dehydrogenase (NAD+)
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
–
–
K
3-methylbenzaldehyde + NADP+ + H2O <=> 3-methylbenzoate + NADPH + H+ 1.2.1.28 benzaldehyde dehydrogenase (NAD+)
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
–
–
K
7-O-methylluteone + NADPH + H+ + O2 <=> dihydrofurano_derivatives + NADP+ + H2O 1.14.99.34 monoprenyl isoflavone epoxidase
–
cathenamine + NADPH + H+ <=> Ajmalicine + NADP+ not assigned
 –
K
cathenamine + NADPH + H+ <=> Tetrahydroalstonine + NADP+ not assigned
 –
K
tabersonine + NADPH + H+ + O2 <=> Lochnericine + NADP+ + H2O not assigned
 –
K
19-epi-Cathenamine + NADPH + H+ <=> 19-epi-Ajmalicine + NADP+ not assigned
 –
K
5-O-beta-D-mycaminosyltylactone + 2 NADPH + 2 O2 + 2 H+ <=> 20-oxo-5-O-beta-mycaminosyltylactone + 2 NADP+ + 3 H2O not assigned
 –
K
malonyl-CoA + 6 methylmalonyl-CoA + 6 NADPH + 6 H+ <=> 8,8a-deoxyoleandolide + 7 CoA + 7 CO2 + H2O + 6 NADP+ not assigned
 –
K
8,8a-deoxyoleandolide + 2 NADPH + 2 H+ + 2 O2 <=> Oleandolide + 2 NADP+ + 3 H2O not assigned
 –
K
6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''2a''''_aglycone + NADPH + O2 <=> 5-Oxoavermectin_''''2a''''_aglycone + NADP+ + H2O 1.14
–
K
6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1a''''_aglycone + NADPH + O2 <=> 5-Oxoavermectin_''''1a''''_aglycone + NADP+ + H2O 1.14
–
K
6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''2b''''_aglycone + NADPH + O2 <=> 5-Oxoavermectin_''''2b''''_aglycone + NADP+ + H2O 1.14
–
K
6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1b''''_aglycone + NADPH + O2 <=> 5-Oxoavermectin_''''1b''''_aglycone + NADP+ + H2O 1.14
–
K
5-Oxoavermectin_''''2a''''_aglycone + NADPH + H+ <=> Avermectin_B2a_aglycone + NADP+ not assigned
 –
K
5-Oxoavermectin_''''1a''''_aglycone + NADPH + H+ <=> Avermectin_B1a_aglycone + NADP+ not assigned
 –
K
5-Oxoavermectin_''''2b''''_aglycone + NADPH + H+ <=> Avermectin_B2b_aglycone + NADP+ not assigned
 –
K
5-Oxoavermectin_''''1b''''_aglycone + NADPH + H+ <=> Avermectin_B1b_aglycone + NADP+ not assigned
 –
K
2-methylbutanoyl-CoA + 5 methylmalonyl-CoA + 7 malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''2a''''_aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+ not assigned
 –
K
2-methylbutanoyl-CoA + 5 methylmalonyl-CoA + 7 malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1a''''_aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+ not assigned
 –
K
isobutyryl-CoA + 5 methylmalonyl-CoA + 7 malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''2b''''_aglycone + 12 CO2 + 13 CoA + 5 H2O + 9 NADP+ not assigned
 –
K
isobutyryl-CoA + 5 methylmalonyl-CoA + 7 malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1b''''_aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+ not assigned
 –
K
2''-Hydroxybiochanin_A + NADPH + H+ <=> Ferreirin + NADP+ 1.3.1.45 2'-hydroxyisoflavone reductase
–
coniferyl_aldehyde + NADPH + H+ + O2 <=> 5-hydroxyconiferaldehyde + NADP+ + H2O 1.14.13
–
K
coniferyl_alcohol + NADPH + H+ + O2 <=> 5-hydroxyconiferyl_alcohol + NADP+ + H2O 1.14.13
–
K
18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + NADPH + H+ <=> C-9_Reduced_nonaketamide + NADP+ 1.1.1
–
K
auraviketone + NADPH + H+ <=> Auramycinone + NADP+ 1.1.1.362 aklaviketone reductase
–
K
apigenin + 2 NADPH + 2 H+ + O2 <=> 2,5,7,4'-tetrahydroxyisoflavanone + 2 NADP+ + H2O not assigned
 –
4-Ethylphenol + NADPH + H+ + O2 <=> 1-(4''-Hydroxyphenyl)ethanol + NADP+ + H2O 1.14.13
–
K
Naphthalene + NADPH + O2 + H+ <=> (1R,2S)-Naphthalene_1,2-oxide + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
Naphthalene + NADPH + O2 + H+ <=> (1S,2R)-Naphthalene_1,2-oxide + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
Naphthalene_dihydrodiol + NADPH + O2 + H+ <=> 1,2-Dihydroxy-3,4-epoxy-1,2,3,4-tetrahydronaphthalene + NADP+ + H2O not assigned
 –
K
2-naphthol + NADPH + O2 + H+ <=> 1,2-dihydroxynaphthalene + NADP+ + H2O not assigned
 –
K
1-Nitronaphthalene + NADPH + O2 + H+ <=> 1-Nitronaphthalene-7,8-oxide + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
1-Nitronaphthalene + NADPH + O2 + H+ <=> 1-Nitronaphthalene-5,6-oxide + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
arachidonic_acid + O2 + NADPH + H+ <=> (5Z,8Z,11Z)-14,15-epoxyeicosatrienoic_acid + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
arachidonic_acid + O2 + NADPH + H+ <=> (5Z,8Z,14Z)-11,12-epoxyeicosatrienoic_acid + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
arachidonic_acid + O2 + NADPH + H+ <=> (5Z,11Z,14Z)-8,9-epoxyeicosatrienoic_acid + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
arachidonic_acid + O2 + NADPH + H+ <=> (8Z,11Z,14Z)-5,6-epoxyeicosatrienoic_acid + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
arachidonic_acid + O2 + NADPH + H+ <=> 16(R)-HETE + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
K
linoleic_acid + O2 + NADPH + H+ <=> (12Z,9R,10S)-9,10-epoxyoctadec-12-enoate + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
linoleic_acid + O2 + NADPH + H+ <=> (9Z)-12,13-epoxyoctadec-9-enoate + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
bromobenzene + NADPH + O2 + H+ <=> Bromobenzene-3,4-oxide + NADP+ + H2O 1.14.13
–
K
bromobenzene + NADPH + O2 + H+ <=> Bromobenzene-2,3-oxide + NADP+ + H2O 1.14.13
–
K
4-Bromophenol + NADPH + O2 + H+ <=> 4-Bromophenol-2,3-epoxide + NADP+ + H2O 1.14.13
–
K
benzo[a]pyrene + NADPH + O2 + H+ <=> Benzo[a]pyrene-9,10-oxide + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
benzo[a]pyrene + NADPH + O2 + H+ <=> benzo[a]pyrene-7,8-epoxide + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
benzo[a]pyrene + NADPH + O2 + H+ <=> benzopyrene_4,5-oxide + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
9-hydroxybenzo(a)pyrene + NADPH + O2 + H+ <=> 9-Hydroxybenzo[a]pyrene-4,5-oxide + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
1,1-dichloroethylene + NADPH + O2 + H+ <=> 2,2-Dichloroacetaldehyde + NADP+ + H2O 1.14.13
–
K
1,1-dichloroethylene + NADPH + O2 + H+ <=> 1,1-Dichloroethylene_epoxide + NADP+ + H2O 1.14.13
–
K
1,1-dichloroethylene + NADPH + O2 + H+ <=> Chloroacetyl_chloride + NADP+ + H2O 1.14.13
–
K
Trichloroethylene + NADPH + O2 + H+ <=> 2,2,3-trichlorooxirane + NADP+ + H2O 1.14.13
1.14.13.25 methane monooxygenase (soluble)
1.14.14.1 unspecific monooxygenase
–
–
–
K
Trichloroethylene + NADPH + O2 + H+ <=> chloral + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
2,2,2-trichloroethanol + 2 NADPH + 2 O2 + 2 H+ <=> trichloroacetate + 2 NADP+ + 3 H2O 1.14.13
–
K
1,2-Dibromoethane + NADPH + O2 + H+ <=> bromoacetaldehyde + NADP+ + H2O + Hydrobromic_acid 1.14.13
–
K
a_ketosteroid + NADPH + H+ + O2 <=> Steroid_lactone + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
–
myristoyl-CoA + NADPH + H+ + O2 <=> (E)-11-tetradecenoyl-CoA + NADP+ + 2 H2O not assigned
 –
myristoyl-CoA + NADPH + H+ + O2 <=> (Z)-11-tetradecenoyl-CoA + NADP+ + 2 H2O not assigned
 –
9 malonyl-CoA + 11 NADPH + 10 H+ + S-adenosyl-L-methionine + [acyl-carrier_protein] <=> Dihydromonacolin_L-[acyl-carrier_protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O 2.3.1.161 lovastatin nonaketide synthase
–
K
L-aspartate + NADP+ <=> iminosuccinate + NADPH + H+ 1.4.1.21 aspartate dehydrogenase
–
K
6-Oxocampestanol + O2 + NADPH <=> Cathasterone + NADP+ + H2O 1.14.13
–
K
ferulic_acid + NADPH + H+ + O2 <=> 5-hydroxyferulic_acid + NADP+ + H2O 1.14.13
–
K
5alpha-campestan-3-one + O2 + NADPH <=> (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + NADP+ + H2O 1.14.13
–
K
typhasterol + NADPH + H+ + O2 <=> 24-epicastasterone + NADP+ + H2O 1.14
–
K
6-deoxotyphasterol + NADPH + H+ + O2 <=> 6-Deoxocastasterone + NADP+ + H2O 1.14
–
K
liquiritigenin + NADPH + H+ + O2 <=> 6,7,4''-Trihydroxyflavanone + NADP+ + H2O 1.14.13
–
K
7,4''-Dihydroxyflavone + 2 NADPH + 2 H+ + O2 <=> 2,7,4''-Trihydroxyisoflavanone + 2 NADP+ + H2O not assigned
 –
2''-Hydroxydihydrodaidzein + NADPH + H+ <=> demethylmedicarpin + NADP+ + H2O not assigned
 –
K
2'',7-Dihydroxy-4'',5''-methylenedioxyisoflavone + NADPH + H+ <=> (+)-Sophorol + NADP+ 1.3.1.45 2'-hydroxyisoflavone reductase
–
K
(+)-Sophorol + NADPH + H+ <=> (+)-maackiain + NADP+ + H2O not assigned
 –
K
(3R)2',7-dihydroxy-dihydro-4',5'-methylenedioxyisoflavone + NADPH + H+ <=> (-)-maackiain + NADP+ + H2O not assigned
 –
K
3-oxooctadecanoyl-[acyl-carrier_protein] + NADPH + H+ <=> (R)-3-hydroxystearoyl-[acyl-carrier_protein] + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
–
–
K
thiobenzamide + O2 + NADPH + H+ <=> Thiobenzamide_S-oxide + NADP+ + H2O 1.14.13
–
K
Thiobenzamide_S-oxide + NADPH + H+ + O2 <=> Thiobenzamide_S,S-dioxide + NADP+ + H2O 1.14.13
–
K
paraxanthine + NADPH + H+ + O2 <=> 1-Methylxanthine + NADP+ + formaldehyde + H2O 1.13.12
–
K
5-deoxyleucopelargonidin + NADP+ <=> 3,7,4'-trihydroxyflavanone + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
K
5-deoxyleucocyanidin + NADP+ <=> fustin + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
K
4-hydroxylamino-2,6-dinitrotoluene + 2 NADPH + 2 H+ <=> 2,4-Dihydroxylamino-6-nitrotoluene + 2 NADP+ + H2O 1.7.1
–
K
2,4-Dihydroxylamino-6-nitrotoluene + NADPH + H+ <=> 4-Amino-2-hydroxylamino-6-nitrotoluene + NADP+ + H2O 1.7.1
–
K
4-hydroxylamino-2,6-dinitrotoluene + NADPH + H+ <=> 4-amino-2,6-dinitrotoluene + NADP+ + H2O 1.7.1
–
K
citronellol + NADP+ <=> (R)-citronellal + NADPH + H+ 1.1.1.183 geraniol dehydrogenase (NADP+)
–
K
(-)-Citronellol + NADP+ <=> (3S)-3,7-dimethyloct-6-enal + NADPH + H+ 1.1.1.183 geraniol dehydrogenase (NADP+)
–
K
tamoxifen + NADPH + O2 + H+ <=> cis-4-hydroxytamoxifen + NADP+ + H2O 1.14.14
1.14.14.1 unspecific monooxygenase
–
–
K
N-Desmethyltamoxifen + NADPH + O2 + H+ <=> trans-endoxifen + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
K
tamoxifen + NADPH + O2 + H+ <=> alpha-hydroxytamoxifen + NADP+ + H2O 1.14.13
–
K
N-Desmethyltamoxifen + NADPH + H+ + O2 <=> alpha-Hydroxy-N-desmethyltamoxifen + H2O + NADP+ 1.14.13
–
K
aldophosphamide + NADP+ + H2O <=> Carboxyphosphamide + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
K
ifosfamide + NADPH + H+ + O2 <=> 4-Hydroxyifosfamide + NADP+ + H2O 1.14.13
1.14.14
–
–
K
lidocaine + NADPH + O2 + H+ <=> 3-Hydroxylidocaine + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
Felbamate + NADPH + H+ + O2 <=> p-Hydroxyfelbamate + NADP+ + H2O 1.14.13
–
K
Felbamate + NADPH + H+ + O2 <=> 2-Hydroxyfelbamate + NADP+ + H2O 1.14.13
–
K
carbamazepine + NADPH + H+ + O2 <=> 3-hydroxycarbamazepine + NADP+ + H2O 1.14.13
–
K
Valproic_acid + NADPH + H+ + O2 <=> 4-Hydroxyvalproic_acid + NADP+ + H2O 1.14.13
1.14.14
–
–
K
Valproic_acid + NADPH + H+ + O2 <=> 5-Hydroxyvalproic_acid + NADP+ + H2O 1.14.13
1.14.14
–
–
K
Valproic_acid + NADPH + H+ + O2 <=> 3-Hydroxyvalproic_acid + NADP+ + H2O 1.14.13
–
K
Bis(glutathionyl)spermine + NADP+ <=> Bis(glutathionyl)spermine_disulfide + NADPH + H+ 1.8.1.12 trypanothione-disulfide reductase
–
K
Homotrypanothione + NADP+ <=> Homotrypanothione_disulfide + NADPH + H+ 1.8.1.12 trypanothione-disulfide reductase
–
K
retinoic_acid + NADPH + H+ + O2 <=> all-trans-5,6-Epoxyretinoic_acid + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
N-Demethylnarwedine + NADPH <=> Norgalanthamine + NADP+ 1.1.1
–
K
(S)-Autumnaline + NADPH + O2 + H+ <=> Isoandrocymbine + NADP+ + 2 H2O 1.14.21
–
K
Cinchoninone + NADPH + H+ <=> Cinchonine + NADP+ not assigned
 –
Quinidinone + NADPH + H+ <=> quinidine + NADP+ not assigned
 –
NADPH + 2 ferricytochrome_b5 <=> NADP+ + 2 ferricytochrome_b5 1.6.2.4 NADPH---hemoprotein reductase
–
Cinchoninone + NADPH + H+ <=> cinchonidine + NADP+ not assigned
 –
Quinidinone + NADPH + H+ <=> Quinine + NADP+ not assigned
 –
Cinchonidinone + NADPH + H+ <=> cinchonidine + NADP+ not assigned
 –
(E,Z)-indolyl-3-acetaldoxime + NADPH + O2 + H+ <=> 1-aci-nitro-2-indolyl-ethane + NADP+ + H2O 1.14.14.45 aromatic aldoxime N-monooxygenase
–
L-homophenylalanine + 2 O2 + 2 NADPH + 2 H+ <=> 3-Phenylpropionaldoxim + 2 NADP+ + CO2 + 3 H2O 1.14.13
–
K
p-hydroxyphenylacetaldoxime + O2 + NADPH + L-cysteine + H+ <=> S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O 1.14
–
L-leucine + 2 O2 + 2 NADPH + 2 H+ <=> (E/Z)-isovaleraldoxime + 3 H2O + 2 NADP+ + CO2 1.14.13
–
K
amino_acid + 2 O2 + 2 NADPH + 2 H+ <=> an_aliphatic_aldoxime + 2 NADP+ + 3 H2O + CO2 1.14.13
–
an_aliphatic_aldoxime + NADPH + O2 + L-cysteine + H+ <=> S-Alkyl-thiohydroximate + NADP+ + 2 H2O 1.14
–
UDP-4-keto-rhamnose + NADPH + H+ <=> UDP-L-rhamnose + NADP+ 1.1.1
–
K
7alpha,27-dihydroxy-4-cholesten-3-one + 2 O2 + 2 NADPH + 2 H+ <=> 7alpha-Hydroxy-3-oxo-4-cholestenoate + 2 NADP+ + 3 H2O not assigned
 –
K
27-Hydroxycholesterol + 2 O2 + 2 NADPH + 2 H+ <=> 5-cholestene-26-oic_acid-3beta-ol + 2 NADP+ + 3 H2O not assigned
 –
K
5-cholestene-26-oic_acid-3beta-ol + O2 + NADPH + H+ <=> 3beta,7alpha-dihydroxy-5-cholestenoic_acid + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
K
benzoate + NADPH + O2 <=> salicylate + NADP+ + H2O 1.14.13
–
K
pregnenolone + NADPH + H+ + O2 <=> 7alpha-hydroxypregnenolone + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
K
11beta-hydroxytestosterone + NADP+ <=> 11beta-hydroxyandrost-4-ene-3,17-dione + NADPH + H+ 1.1.1.62 17beta-estradiol 17-dehydrogenase
–
K
1,2,3,4-tetrachlorobenzene + O2 + NADPH + H+ <=> cis-Chlorobenzene_dihydrodiol + NADP+ 1.14.12
–
K
cis-Chlorobenzene_dihydrodiol + NADP+ <=> tetrachlorocatechol + NADPH + H+ 1.3.1
–
K
2,3,5-trichloromaleylacetate + 2 NADPH + 2 H+ <=> 2,4-dichloro-3-oxohexanedioic_acid + 2 NADP+ + Hydrochloric_acid 1.3.1.32 maleylacetate reductase
–
K
6-methylpretetramide + 2 NADPH + 2 H+ + 2 O2 <=> 4-de(dimethylamino)-4-oxoanhydrotetracycline + 2 NADP+ + 2 H2O 1.14.13.232 6-methylpretetramide 4-monooxygenase
1.14.13.233 4-hydroxy-6-methylpretetramide 12a-monooxygenase
–
–
K
Anhydrochlortetracycline + O2 + NADPH + H+ <=> 5a,11a-Dehydrochlortetracycline + NADP+ + H2O 1.14.13.38 anhydrotetracycline 6-monooxygenase
–
5a,11a-Dehydrochlortetracycline + NADPH + H+ <=> chlortetracycline + NADP+ not assigned
 –
2-Amino-4-nitrotoluene + 3 NADPH + 3 H+ <=> 2,4-Diaminotoluene + 3 NADP+ + 2 H2O 1.7.1
–
K
2,4-dinitrotoluene + 3 NADPH + 3 H+ <=> 2-Amino-4-nitrotoluene + 3 NADP+ + 2 H2O 1.7.1
–
K
2,4-dinitrotoluene + 3 NADPH + 3 H+ <=> 4-amino-2-nitrotoluene + 3 NADP+ + 2 H2O 1.7.1
–
K
4-amino-2-nitrotoluene + 3 NADPH + 3 H+ <=> 2,4-Diaminotoluene + 3 NADP+ + 2 H2O 1.7.1
–
K
7,9,12-Octaketide_intermediate_1 + NADPH + H+ <=> 7,9,12-Octaketide_intermediate_2 + NADP+ 1.1.1
–
K
7,9,12-Decaketide_intermediate_1 + NADPH + H+ <=> 7,9,12-Decaketide_intermediate_2 + NADP+ 1.1.1
–
K
7,9,12-Decaketide_intermediate_4 + NADPH + H+ <=> 7,9,12-Decaketide_intermediate_5 + NADP+ 1.1.1
–
K
5,5''-Dehydrodivanillate + O2 + NADPH + H+ <=> 2,2'',3-Trihydroxy-3''-methoxy-5,5''-dicarboxybiphenyl + NADP+ + H2O + formaldehyde not assigned
 –
K
Octaketide_bicyclic_intermediate + NADPH + H+ <=> (S)-Chiral_alcohol + NADP+ 1.1.1
–
K
Octaketide_bicyclic_intermediate + NADPH + H+ <=> (R)-Chiral_alcohol + NADP+ 1.1.1
–
K
nogalaviketone + NADPH + H+ <=> Nogalavinone + NADP+ 1.1.1
–
K
Premithramycin_B + NADPH + H+ + O2 <=> Mithramycin_DK + NADP+ + CO2 1.14.13
–
K
Aflatoxin_M1 + O2 + NADPH + H+ <=> Aflatoxin-M1-8,9-epoxide + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
K
aflatoxin_B1 + O2 + NADPH + H+ <=> Aflatoxin_B1-endo-8,9-epoxide + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
K
7,12-dimethylbenz[a]anthracene + O2 + NADPH + H+ <=> 1a,11b-Dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
K
trans-3,4-Dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene + O2 + NADPH + H+ <=> (1aalpha,2beta,3alpha,11calpha)-1a,2,3,11c-Tetrahydro-6,11-dimethylbenzo[6,7]phenanthro[3,4-b]oxirene-2,3-diol + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
K
4-methylnitrosamino-1-(3-pyridyl)-1-butanone + O2 + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP+ 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
4-methylnitrosamino-1-(3-pyridyl)-1-butanone + O2 + NADPH + H+ <=> 4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O + NADP+ 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
4-methylnitrosamino-1-(3-pyridyl)-1-butanol + O2 + NADPH + H+ <=> 1-(Methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol + H2O + NADP+ 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
4-methylnitrosamino-1-(3-pyridyl)-1-butanol + O2 + NADPH + H+ <=> alpha-[3-[(Hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol + H2O + NADP+ 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
7,12-dimethylbenz[a]anthracene + O2 + NADPH + H+ <=> 7-hydroxymethyl-12-methylbenz[a]anthracene + H2O + NADP+ 1.14.13
–
K
7,12-dimethylbenz[a]anthracene + O2 + NADPH + H+ <=> 7,12-Dimethylbenz[a]anthracene_5,6-oxide + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
K
trans-2-enoyl-CoA + NADPH + H+ <=> palmitoyl-CoA + NADP+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
cis-9,10-epoxystearic_acid + NADPH + O2 + H+ <=> 18-hydroxy-9(10)-epoxystearic_acid + NADP+ + H2O 1.14
–
K
behenic_acid + NADPH + O2 + H+ <=> 22-Hydroxydocosanoate + NADP+ + H2O 1.14
–
K
16-hydroxypalmitic_acid + NADPH + O2 + H+ <=> 10,16-dihydroxyhexadecanoic_acid + NADP+ + H2O 1.14
–
K
9,10-dihydroxystearic_acid + NADPH + O2 + H+ <=> 9,10,18-trihydroxyoctadecanoic_acid + NADP+ + H2O 1.14
–
K
palmitoyl-CoA + 2 NADPH + 2 H+ <=> an_alcohol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
K
LysW-gamma-L-alpha-aminoadipyl_6-phosphate + NADPH + H+ <=> LysW-gamma-L-alpha-aminoadipate_6-semialdehyde + NADP+ + phosphate 1.2.1.103 [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase
–
K
(Z)-2-methylbutanal_oxime + NADPH + H+ + O2 <=> (2R)-2-hydroxy-2-methylbutanenitrile + NADP+ + 2 H2O not assigned
 –
K
Isobutyraldoxime + NADPH + H+ + O2 <=> acetone_cyanohydrin + NADP+ + 2 H2O not assigned
 –
K
3-Ketoglutaryl-[acp]_methyl_ester + NADPH + H+ <=> 3-Hydroxyglutaryl-[acp]_methyl_ester + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
K
Enoylglutaryl-[acp]_methyl_ester + NADPH + H+ <=> Glutaryl-[acp]_methyl_ester + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
K
Enoylpimeloyl-[acp]_methyl_ester + NADPH + H+ <=> pimelyl-[acyl-carrier_protein]_methyl_ester + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
K
biotin_sulfoxide + NADPH + H+ <=> biotin + NADP+ + H2O 1
–
K
Paspaline_B + NADPH + H+ + O2 <=> 12-Demethyl-11,12-dehydropaspaline + NADP+ + H2O + formate 1.14.13
–
K
12-Demethyl-11,12-dehydropaspaline + O2 + NADPH + H+ <=> beta-PC-M6 + NADP+ + H2O 1.14.13
–
K
beta-PC-M6 + O2 + NADPH + H+ <=> 13-Desoxypaxilline + NADP+ + 2 H2O 1.14.13
–
K
13-Desoxypaxilline + NADPH + H+ + O2 <=> Paxilline + NADP+ + H2O 1.14.13
–
K
13-Desoxypaxilline + NADPH + O2 + H+ <=> Paspalicine + NADP+ + 2 H2O not assigned
 –
K
Paspalicine + O2 + NADPH + H+ <=> Paspalinine + NADP+ + H2O 1.14.13
–
K
13-Desoxyterpendole_I + NADPH + H+ + O2 <=> Terpendole_I + NADP+ + H2O 1.14.13
–
K
20,21-Diprenylterpendole_I + 3 O2 + 3 NADPH + 3 H+ <=> Lolitriol + 3 NADP+ + 4 H2O 1.14.13
–
K
Lolitrem_E + NADPH + O2 + H+ <=> Lolitrem_B + NADP+ + 2 H2O 1.14.21
–
K
Paspaline + 2 NADPH + 2 H+ + 2 O2 <=> Paspaline_B + 2 NADP+ + 3 H2O 1.14.13
–
K
Paspaline + O2 + NADPH + H+ <=> Terpendole_E + NADP+ + H2O 1.14.13
–
K
Terpendole_E + 4 NADPH + 4 O2 + 4 H+ <=> 13-Desoxyterpendole_I + formate + 4 NADP+ + 5 H2O 1.14.13
–
K
12-Demethyl-11,12-dehydropaspaline + 3 O2 + 3 NADPH + 3 H+ <=> Terpendole_I + 3 NADP+ + 3 H2O 1.14.13
–
K
Terpendole_J + NADPH + O2 + H+ <=> terpendole_C + NADP+ + 2 H2O 1.14.21
–
K
(1''S,5''S)-Averufin + NADPH + H+ + O2 <=> 1''-Hydroxyversicolorone + NADP+ + H2O not assigned
 –
K
versicolorin_B + O2 + NADPH + H+ <=> Versicolorin_A + NADP+ + 2 H2O not assigned
 –
K
hexadecanal + protein + NADP+ <=> a_[protein]-S-(long-chain-acyl)-L-cysteine + NADPH + H+ 1.2.1.50 long-chain acyl-protein thioester reductase
–
(Z)-phenylacetaldoxime + NADPH + O2 + H+ <=> mandelonitrile + NADP+ + 2 H2O not assigned
 –
(E)-phenylacetaldoxime + L-cysteine + NADPH + O2 + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O 1.14.14.45 aromatic aldoxime N-monooxygenase
–
K
p-hydroxyphenylacetaldoxime + L-cysteine + NADPH + O2 + H+ <=> S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O 1.14.14.45 aromatic aldoxime N-monooxygenase
–
K
20,21-Diprenylterpendole_J + 3 O2 + 3 NADPH + 3 H+ <=> Lolitrem_E + 3 NADP+ + 4 H2O 1.14.13
–
K
20,21-Diprenylterpendole_C + 3 O2 + 3 NADPH + 3 H+ <=> Lolitrem_B + 3 NADP+ + 4 H2O 1.14.13
–
K
nocardicin_C + 2 NADPH + 2 H+ + 2 O2 <=> nocardicin_A + 2 NADP+ + 3 H2O 1.14.13
–
K
LysW-L-glutamyl_5-phosphate + NADPH + H+ <=> LysW-L-glutamate_5-semialdehyde + NADP+ + phosphate 1.2.1
–
K
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ <=> dTDP-4-oxo-2,6-dideoxy-D-allose + NADP+ 1.1.1
–
K
24-methylene_cholesterol + NADPH + H+ <=> ergosta-5-enol + NADP+ 1.3.1
–
K
3''''-Oxoribostamycin + NADPH + H+ <=> Xylostasin + NADP+ 1.1.1
–
K
4''-Oxolividamine + NADPH + H+ <=> Lividamine + NADP+ 1.1.1
–
K
4''-Oxonebramine + NADPH + H+ <=> nebramine + NADP+ 1.1.1
–
K
8 malonyl-CoA + 7 NADPH + 7 H+ + [acyl-carrier_protein] <=> 3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] + 8 CoA + 8 CO2 + 6 H2O + 7 NADP+ not assigned
 –
K
2 malonyl-CoA + [acyl-carrier_protein] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine <=> (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O 2.3.1.244 2-methylbutanoate polyketide synthase
–
K
arachidoyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + 8 H+ + [acyl-carrier_protein] <=> C32-Mycocerosyl-[acp] + 5 CoA + 4 CO2 + 8 NADP+ + 4 H2O 2.3.1.111 mycocerosate synthase
–
stearoyl-CoA + 3 methylmalonyl-CoA + 6 NADPH + 6 H+ + [acyl-carrier_protein] <=> C27-Mycolipanoyl-[acp] + 4 CoA + 3 CO2 + 6 NADP+ + 3 H2O 2.3.1.252 mycolipanoate synthase
–
dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + NADPH + H+ <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + NADP+ 1.1.1
–
K
oxytetracycline + NADPH + H+ + O2 <=> 11a-hydroxy-oxytetracycline + NADP+ + H2O 1.14.13.231 tetracycline 11a-monooxygenase
–
K
chlortetracycline + NADPH + H+ + O2 <=> 11a-Hydroxy-7-chlortetracycline + NADP+ + H2O 1.14.13.231 tetracycline 11a-monooxygenase
–
K
4-Hydroxybenzoyl-[acp] + 8 malonyl-CoA + 16 NADPH + 16 H+ <=> 17-(4-Hydroxyphenyl)heptadecanoyl-[acp] + 8 CO2 + 8 CoA + 16 NADP+ + 8 H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
4-Hydroxybenzoyl-[acp] + 9 malonyl-CoA + 18 NADPH + 18 H+ <=> 19-(4-Hydroxyphenyl)nonadecanoyl-[acp] + 9 CO2 + 9 CoA + 18 NADP+ + 9 H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
6-(1''-Hydroxy-2''-oxopropyl)-tetrahydropterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
–
K
acetohydrazide + NADPH + H+ + O2 <=> Hepatotoxins + NADP+ + H2O 1.14.13
–
K
Isonicotinoyl_radical + NADP+ <=> Isonicotinoyl-NADP_adduct not assigned
 –
K
[(3S,4R)-4-Alkanoyl-5-oxooxolan-3-yl]methyl_phosphate + NADP+ <=> a_(4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl_phosphate + NADPH + H+ 1.3.1.113 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase
–
9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic_acid + NADPH + H+ <=> 9-Hydroxy-12-oxo-15(Z)-octadecenoic_acid + NADP+ 1.3.1
–
K
D-arabinofuranose + NADP+ <=> D-arabinono-1,4-lactone + NADPH + H+ 1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
–
M
(6R)-6-lactoyl-5,6,7,8-tetrahydropterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+ 1.1.1.220 6-pyruvoyltetrahydropterin 2'-reductase
–
M
D-sorbitol + NADP+ <=> keto-L-sorbose + NADPH + H+ 1.1.1.289 sorbose reductase
–
3-Hydroxy-2-methylpyridine-5-carboxylate + O2 + NADPH <=> 2-(acetylaminomethylene)succinate + NADP+ 1.14.13.242 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase
–
M
7-O-methylluteone + O2 + NADPH + H+ <=> 7-O-methylluteone_epoxide + H2O + NADP+ 1.14.99.34 monoprenyl isoflavone epoxidase
–
a_protein_with_reduced_L-cysteine_residues + NADP+ <=> a_protein_with_a_disulfide_bond + NADPH + H+ 1.8.1.8 protein-disulfide reductase
–
cob(II)alamin-[cyanocobalamin_reductase_CblC] + NADP+ + cyanide <=> vitamin_B12 + [cyanocobalamin_reductase_CblC] + NADPH + H+ 1.16.1.6 cyanocobalamin reductase (cyanide-eliminating)
–
M
2-methoxy-6-(all-trans-octaprenyl)phenol + O2 + NADPH + H+ <=> 2-methoxy-6-octaprenyl-1,4-benzoquinol + H2O + NADP+ 1.14.13.M56
–
M
methylcob(III)alamin-[methionine_synthase] + S-adenosyl-L-homocysteine + NADP+ + H+ <=> S-adenosyl-L-methionine + cob(II)alamin-[methionine_synthase] + NADPH 1.16.1.8 [methionine synthase] reductase
–
M
5,10-methylenetetrahydrofolate + uracil54_in_tRNA + NADPH + H+ <=> tetrahydrofolate + 5-methyluracil54_in_tRNA + NADP+ 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]
–
S-adenosyl-L-methionine + malonyl-CoA + lovastatin_nonaketide_synthase + NADPH + H+ <=> dihydromonacolin_L-[lovastatin_nonaketide_synthase] + S-adenosyl-L-homocysteine + CO2 + CoA + H2O + NADP+ 2.3.1.161 lovastatin nonaketide synthase
–
M
2R,3R-2,3-dihydroxy-3-methylpentanoate + NADP+ <=> H+ + (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
M
5-chloro-3-oxoadipate + NADP+ <=> 2-chloromaleylacetate + NADPH + H+ 1.3.1.32 maleylacetate reductase
–
M
2,3,4-saturated_fatty_acyl-[acp] + NADP+ <=> NADPH + trans-2,3-dehydroacyl-[acyl-carrier_protein] + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
–
–
–
M
NADPH + oxidized_flavoprotein_(FAD) + H+ <=> NADP+ + reduced_flavoprotein_(FADH2) not assigned
 –
NADPH + Ox-FMN-Flavoproteins + H+ <=> NADP+ + Red-FMNH2-Flavoproteins not assigned
 –
keto-D-fructose + NADP+ <=> NADPH + 5-dehydro-D-fructose + H+ 1.1.1.124 fructose 5-dehydrogenase (NADP+)
–
19E-geissoschizine + NADP+ <=> 4,21-Dehydrogeissoschizine + NADPH 1.3.1.36 geissoschizine dehydrogenase
–
M
L-gulonate + NADP+ <=> aldehydo-D-glucuronate + NADPH + H+ 1.1.1.19 glucuronate reductase
–
M
(S)-4-Amino-5-oxopentanoate + NADP+ + tRNAMet <=> L-glutamyl-[tRNAGlu] + NADPH + H+ 1.2.1.70 glutamyl-tRNA reductase
–
M
D-galactose + NADP+ <=> 3-Keto-beta-D-galactose + NADPH + H+ 1.1.1
–
M
D-glucose + NADP+ <=> 3-dehydro-D-glucose + NADPH + H+ 1.1.1
–
M
L-xylopyranose + NADP+ <=> H+ + NADPH + L-xylono-1,4-lactone 1.1.1.113 L-xylose 1-dehydrogenase
–
D-mannitol + NADP+ <=> keto-D-fructose + NADPH + H+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
–
(R)-mevalonate + NADP+ <=> (R)-mevaldate + NADPH + H+ 1.1.1.33 mevaldate reductase (NADPH)
–
long-chain_fatty_acyl-[mycocerosate_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> tetramethylated_mycocerosyl-[mycocerosate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.111 mycocerosate synthase
–
H+ + NADPH + plastoquinone <=> H+ + NADP+ + plastoquinol 7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
–
M
electron-transfer_quinone + H+ + NADPH <=> electron-transfer_quinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
nitroglycerin + NADPH <=> 1,3-glyceryl_dinitrate + nitrite + NADP+ 4.99.1
–
M
1,3-glyceryl_dinitrate + NADPH <=> 1-mononitroglycerol + nitrite + NADP+ 4.99.1
–
M
nitroglycerin + NADPH <=> nitrite + 1,2-dinitroglycerol + NADP+ 4.99.1
–
M
1,2-dinitroglycerol + NADPH <=> 1-mononitroglycerol + nitrite + NADP+ 4.99.1
–
M
oxidized_nitroaromatic_compound + NADPH <=> reduced_nitroaromatic_compound + NADP+ 1
–
4-nitrobenzoate + NADPH + H+ <=> 4-hydroxyylaminobenzoate + H2O + NADP+ 1.7.1
–
M
aldehydo-D-ribose + H2O + NADP+ <=> NADPH + D-ribonate + H+ 1.1.1.115 ribose 1-dehydrogenase (NADP+)
–
(3R)-3-hydroxyhexacosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxohexacosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.86 fatty-acyl-CoA synthase system
–
M
cerotoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-hexacos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.86 fatty-acyl-CoA synthase system
–
M
3-chlorophenol + O2 + NADPH + H+ <=> 3-chlorocatechol + H2O + NADP+ 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
M
very-long-chain_fatty_aldehyde + CoA + NADP+ <=> behenoyl-CoA + NADPH + H+ 1.2.1
–
M
jasmonic_acid + O2 + NADPH + H+ <=> trans-11-hydroxyjasmonate + NADP+ + H2O 1.14.13
–
palmitoyl-CoA + NADPH + O2 + H+ <=> 16-hydroxypalmitoyl-CoA + NADP+ + H2O 1.14.13
–
16-hydroxypalmitoyl-CoA + NADPH + O2 + H+ <=> 10,16-dihydroxypalmitoyl-CoA + NADP+ + H2O 1.14.13
–
M
plectaniaxanthin + O2 + NADPH + H+ <=> myxol + H2O + NADP+ 1.14.13
–
M
(3R,7Z)-3-hydroxytetradec-7-enoyl-[acp] + NADP+ <=> (7Z)-3-oxotetradec-7-enoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,9Z)-3-hydroxyhexadec-9-enoyl-[acp] + NADP+ <=> (9Z)-3-oxohexadec-9-enoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(2R,3S)-flavan-3-ol + NADP+ + H2O <=> (2R,3S,4S)-leucoanthocyanidin + NADPH + H+ 1.17.1.3 leucoanthocyanidin reductase
–
M
H+ + coniferyl_aldehyde + NADPH <=> dihydroconiferyl_aldehyde + NADP+ not assigned
 –
M
H+ + dihydroconiferyl_aldehyde + NADPH <=> dihydroconiferyl_alcohol + NADP+ not assigned
 –
M
UDP-L-rhamnose + NADP+ <=> UDP-4-dehydro-6-deoxy-L-mannose + NADPH + H+ 1.1.1
–
M
acetyl-CoA + malonyl-CoA + NADPH + H+ + O2 <=> hexaketide_pyrone + CO2 + CoA + H2O + NADP+ 2.3.1
–
acetyl-CoA + malonyl-CoA + NADPH + H+ + O2 <=> 1,8-dihydroxy-3-methylnaphthalene + CO2 + CoA + NADP+ + H2O 2.3.1
–
M
Formylphosphonate + H2O + NADP+ <=> Phosphonoformate + NADPH + H+ 1.2.1
–
M
hydroxymethylphosphonate + NADP+ <=> Formylphosphonate + NADPH + H+ 1.1.1
–
M
ascorbate + NADP+ <=> dehydroascorbate + NADPH + H+ not assigned
 –
M
putrescine + O2 + NADPH <=> N-hydroxyputrescine + H2O + NADP+ 1.14.13.M63
–
M
H+ + N-hydroxy-N-succinyl-putrescine + NADPH + O2 <=> 3-[4-amino-3-hydroxybutyl]-hydroxy-carbamoyl-propanoate + NADP+ + H2O not assigned
 –
M
S-adenosyl-L-methionine + (2-hydroxybenzoyl)adenylate + L-cysteine + malonyl-CoA + NADPH + H+ <=> yersiniabactin + CoA + S-adenosyl-L-homocysteine + NADP+ + H2O + AMP 2.3.1
–
M
S-adenosyl-L-methionine + salicylate + L-cysteine + NADPH <=> pyochelin + S-adenosyl-L-homocysteine + NADP+ + H2O not assigned
 –
hydroxyphenyl-4,2-bis-thiazolinyl-[PchF_non-ribosomal_peptide_synthase] + NADPH + H+ <=> N-desmethyl-pyochelin-[PchF_non-ribosomal_peptide_synthase] + NADP+ not assigned
 –
M
elymoclavine_aldehyde + O2 + NADPH <=> paspalic_acid + H2O + NADP+ 1.14.13
–
M
agroclavine + O2 + NADPH + H+ <=> elymoclavine + NADP+ + H2O 1.14.13
–
M
(3R)-3-hydroxyglutaryl-[acp]_methyl_ester + NADP+ <=> 3-Ketoglutaryl-[acp]_methyl_ester + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
benzylsulfanol + NADP+ <=> (Z)-phenylmethanethial_S-oxide + NADPH + H+ 1.1.1.M1
–
M
daidzein + NADPH + H+ <=> (S)-dihydrodaidzein + NADP+ 1.3.1
–
M
(2S)-3-sulfopropanediol + NADP+ <=> 1-hydroxy-2-oxo-3-sulfopropane + NADPH + H+ 1.1.1
–
M
4alpha-methylzymosterol + NADP+ <=> 4alpha-methyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ 1.3.1
–
M
3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + H+ + NADPH + O2 <=> UWM6 + CO2 + H2O + NADP+ 2.3.1
–
M
2,3-Dehydro-UWM6 + O2 + NADPH + H+ <=> 8-methyltetraphene-1,5,6,11,12-pentol + H2O + NADP+ not assigned
 –
M
apo-4''-lycopenal + NADP+ + H2O <=> apo-4''-lycopenoate + H+ + NADPH 1.2.1
–
M
3-dehydroshikimate + NADP+ <=> 3,5-didehydroshikimate + NADPH + H+ not assigned
 –
M
(9Z)-12,13-dihydroxyoctadec-9-enoic_acid + O2 + NADPH + H+ <=> (9Z)-12,13,17-trihydroxyoctadeca-9-enoate + NADP+ + H2O 1.14.13
–
M
[(1R,2R,3S,4S)-4-{5-cyano-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-7-yl}-2,3-dihydroxycyclopentyl]methyl_phosphate + NH3 + NADP+ <=> 5-phospho-alpha-D-ribose-1-preQ0 + NADPH + H+ 1.7.1
–
M
22-hydroxy-docosanoyl-CoA + NADP+ <=> 22-oxo-docosanoyl-CoA + NADPH + H+ 1.1.1
–
M
22-oxo-docosanoyl-CoA + NADP+ + H2O <=> 22-carboxy-docosanoyl-CoA + NADPH + H+ 1.2.1
–
M
L-Rhamnofuranose + NADP+ <=> L-Rhamno-1,4-lactone + NADPH + H+ 1.1.1.378 L-rhamnose 1-dehydrogenase [NAD(P)+]
–
M
polyhydroxylated_tetraketide_alpha-pyrone + NADP+ <=> hydroxylated_tetraketide_alpha-pyrone + NADPH + H+ 1.1.1
–
pinitol + NADP+ <=> 4-O-methyl-D-myo-inosose + NADPH + H+ 1.1.1
–
M
benzoate + O2 + NADPH + H+ <=> 1-hydroxy-6-oxocyclohex-2-ene-1-carboxylate + NADP+ 1.14.13
–
M
benzaldehyde + O2 + NADPH + H+ <=> 1-hydroxy-6-oxocyclohex-2-ene-1-carboxylate + H2O + NADP+ 1.13.12
–
M
acetone + NADP+ <=> enone + NADPH + H+ 1.3.1
–
(Z)-but-2-enal + NADPH + H+ <=> Butyraldehyde + NADP+ 1.3.1
–
M
(Z)-but-2-enal + NADPH + H+ <=> cis-2-buten-1-ol + NADP+ 1.1.1
–
plastoquinone + NADPH + H+ <=> plastoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
M
(+)-alpha-santalene + O2 + NADPH + H+ <=> (+)-alpha-santalol + H2O + NADP+ 1.14.13
–
(R)-3-hydroxyvaleryl-CoA + NADP+ <=> 3-oxopentanoyl-CoA + NADPH + H+ 1.1.1.36 acetoacetyl-CoA reductase
–
M
kauralexin_A3 + NADPH + O2 <=> NADP+ + H2O + kauralexin_A2 1.14.13
–
M
ent-kaurene + H+ + NADPH + O2 <=> kauralexin_A1 + H2O + NADP+ 1.14.13
–
M
kauralexin_B3 + NADPH + O2 <=> NADP+ + H2O + kauralexin_B2 1.14.13
–
M
ent-isokaurene + H+ + NADPH + O2 <=> kauralexin_B1 + H2O + NADP+ 1.14.13
–
M
L(-)threo-Sphinganine + NADP+ <=> 3-dehydrosphinganine + NADPH + H+ 1.1.1.102 3-dehydrosphinganine reductase
–
glycyrrhetinic_acid + NADP+ <=> 3,11-dioxoolean-12-en-30-oic_acid + NADPH + H+ 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
–
androsterone + NADP+ <=> dehydroepiandrosterone + NADPH + H+ 1.3.1
–
5-hydroxy-3-[(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + NADP+ <=> 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + NADPH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
M
Glutathioselenol + glutathione + NADP+ <=> Selenodiglutathione + NADPH + H+ 1.8.1
–
M
selenium + glutathione + NADP+ <=> Glutathioselenol + NADPH + H+ 1.8.1
–
M
acetyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> 8,8a-deoxyoleandolide + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
dTDP-D-boivinose + NADP+ <=> dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1
–
M
dTDP-D-oliose + NADP+ <=> dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1
–
M
dTDP-D-mycarose + NADP+ <=> dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1
–
M
dTDP-4-oxo-2,6-dideoxy-D-allose + NADP+ <=> dTDP-(2R,6S)-2,4-dihydroxy-6-methyl-2,6-dihydropyran-3-one + NADPH + H+ 1.17.1
–
M
(-)-endo-fenchol + NADP+ <=> 1,3,3-trimethyl-bicyclo[2.2.1]heptan-2-one + NADPH + H+ 1.1.1.322 (-)-endo-fenchol dehydrogenase
–
3-oxodihomo_gamma-linolenoyl-CoA + NADPH + H+ <=> (3R)-hydroxydihomo_gamma-linolenoyl-CoA + NADP+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA + NADP+ <=> (11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(3R,7Z,10Z,13Z,16Z,19Z)-3-hydroxydocosa-7,10,13,16,19-pentaenoyl-[acp] + NADP+ <=> (7Z,10Z,13Z,16Z,19Z)-3-oxodocosa-7,10,13,16,19-pentaenoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
H+ + nicotinate + NADPH <=> 3,6-Dihydronicotinate + NADP+ not assigned
 –
M
3,6-dihydronicotine + NADP+ <=> Nicotine + NADPH + H+ 1.1.1
–
M
(S)-dihydrodaidzein + NADPH + H+ <=> (3R,4S)-tetrahydrodaidzein + NADP+ 1.3.1
–
M
CDP-D-xylulose + NADPH + H+ <=> CDParabitol + NADP+ not assigned
 –
M
L-threo-(6R,1'S,2'S)-5,6,7,8-tetrahydrobiopterin + NADP+ <=> (6R)-6-lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+ not assigned
 –
M
hexadecanal + O2 + NADPH + H+ <=> a_long-chain_alkane + formate + H2O + NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
M
(3R)-3-hydroxyacyl-CoA + NADP+ <=> 3-oxoacyl-CoA + NADPH + H+ 1.1.1.36 acetoacetyl-CoA reductase
–
(3R)-3-hydroxybehenoyl-CoA + NADP+ <=> 3-oxobehenoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(3R)-3-hydroxycerotoyl-CoA + NADP+ <=> 3-oxocerotoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
lignoceroyl-CoA + NADP+ <=> trans-lignocer-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
hexacosanoyl-CoA + NADP+ <=> trans-cerot-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
(3R)-all-trans-3-hydroxyretinol-[retinoid-binding_protein] + NADP+ <=> (3R)-all-trans-3-hydroxyretinal-[retinoid-binding_protein] + NADPH + H+ 1.1.1
–
M
(3S)-11-cis-3-hydroxyretinol-[retinoid-binding_protein] + NADP+ <=> (3S)-11-cis-3-hydroxyretinal-[retinoid-binding_protein] + NADPH + H+ 1.1.1
–
M
all-trans-3-hydroxyretinol-[retinoid-binding_protein] + NADP+ <=> NADPH + H+ + all-trans-3-hydroxyretinal-[retinoid-binding_protein] 1.1.1
–
M
11-cis-3-hydroxyretinol-[retinoid-binding_protein] + NADP+ <=> 11-cis-3-hydroxyretinal-[retinoid-binding_protein] + NADPH + H+ 1.1.1
–
M
Premithramycin_B + O2 + NADPH + H+ <=> premithramycin_B_lactone + H2O + NADP+ 1.14.13
–
M
mithramycin + NADP+ <=> Mithramycin_DK + NADPH + H+ 1.1.1
–
M
(2S)-2-hydroxy-2-[4,5,7,10-tetrahydroxy-3-(3-oxobutanoyl)anthracen-2-yl]acetyl-[PKS-acp] + NADP+ <=> 2-oxo-2-[4,5,7,10-tetrahydroxy-3-(3-oxobutanoyl)anthracen-2-yl]acetyl-[PKS-acp] + NADPH + H+ 1.1.1
–
M
(4S)-2-acetyl-3,4,8,10,11,12-hexahydroxy-1,4-dihydrotetracen-1-one + O2 + NADPH + H+ <=> 4-demethylpremithracinone + H2O + NADP+ not assigned
 –
M
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> eicosapentaenoic_acid + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA + NADP+ <=> (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
elymoclavine + O2 + NADPH + H+ <=> elymoclavine_aldehyde + H2O + NADP+ 1.14.13
–
M
ent-kaur-16-en-19-oate + NADPH + O2 + H+ <=> steviol + NADP+ + H2O 1.14.13
–
M
Diethylamine + O2 + NADPH <=> diethylamine_N-oxide + H2O + NADP+ 1.14.13
–
M
H+ + ethylamine + O2 + NADPH <=> acetaldehyde + NH3 + NADP+ + H2O 1.14.13
–
M
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> spinosyn_macrolactone + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
dTDP-L-megosamine + NADP+ <=> dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose + NADPH + H+ 1.1.1
–
M
CDP-D-fructose + NADPH + H+ <=> CDP-D-mannitol + NADP+ not assigned
 –
M
D-idonate + NADP+ <=> 5-Dehydro-L-gluconate + NADPH + H+ 1.1.1
–
M
3,7,4''-trimethylquercetin + O2 + NADPH + H+ <=> 2''-hydroxy_3,7,4''-trimethylquercetin + NADP+ + H2O 1.14.13
–
M
3,6,7,4''-tetramethylquercetagetin + O2 + NADPH + H+ <=> 2''-hydroxy_3,6,7,4''-tetramethylquercetagetin + NADP+ + H2O 1.14.13
–
M
oxidized_nitroaromatic_compound + NADPH <=> reduced_nitroaromatic_compound + NADP+ 1.7.1
–
3-Amino-4-hydroxybenzoic_acid + ATP + NADPH + H+ <=> 3-amino-4-hydroxybenzaldehyde + AMP + NADP+ + diphosphate not assigned
 –
M
ergosta-7,25(27)-dienol + H+ + NADPH <=> 5alpha-ergosta-7-en-3beta-ol + NADP+ 1.3.1
–
M
ergosta-5,7-dienol + NADP+ <=> ergosterol + NADPH + H+ 1.3.1
–
M
porifersta-5,7-dienol + NADP+ <=> 7-dehydroporiferasterol + NADPH + H+ 1.3.1
–
M
porifersta-7,25(27)-dienol + H+ + NADPH <=> poriferst-7-enol + NADP+ 1.3.1
–
M
hydroperoxy_fatty_acid + NADPH + H+ <=> hydroxylated_fatty_acid + H2O + NADP+ 1.11.1.22 hydroperoxy fatty acid reductase
–
(9Z,11E,13S,15Z)-13-hydroxyoctadeca-9,11,15-trienoic_acid + H2O + NADP+ <=> (9Z,11E,13S,15Z)-13-hydroperoxy-9,11,15-octadecatrienoate + NADPH + H+ 1.11.1
–
chrysin + NADPH + O2 + H+ <=> baicalein + NADP+ + H2O 1.14.13
–
M
meso-2,6-diaminoheptanedioate + NADP+ <=> (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NH3 + NADPH + H+ not assigned
 –
3R-hydroxy-(11Z)-eicos-11-enoyl-CoA + NADP+ <=> 3-oxo-eicosenoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(2E,11Z)-icosa-2,11-dienoyl-CoA + NADPH + H+ <=> eicosenoyl-CoA + NADP+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
3R-hydroxy-lesqueroloyl-CoA + NADP+ <=> 3-oxo-lesqueroloyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
trans-lesqueroloyl-CoA + NADPH + H+ <=> lesqueroloyl-CoA + NADP+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
L-tyrosine-S-[NovH_protein] + O2 + NADPH + H+ <=> (R)-beta-hydroxy-L-tyrosine-S-[NovH_protein] + NADP+ + H2O 1.14.13
–
M
(R)-beta-hydroxy-L-tyrosine-S-[NovH_protein] + NADP+ <=> beta-oxo-L-tyrosine-S-[NovH_protein] + NADPH + H+ 1.1.1
–
M
beta-oxo-L-tyrosine-S-[NovH_protein] + O2 + NADPH + H+ <=> 2''-hydroxy-beta-oxo-L-tyrosine-S-[NovH_protein] + NADP+ + H2O 1.14.13
–
M
14alpha-hydroxy-cholesta-4,7-diene-3,6-dione + NADPH + H+ <=> 14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione + NADP+ 1.3.1
–
M
(2S,5S)-hexanediol + NADP+ <=> 2,5-hexanedione + NADPH + H+ 1.1.1.283 methylglyoxal reductase (NADPH)
–
(1R)-3-chloro-1-phenylpropan-1-ol + NADP+ <=> 3-chloropropiophenone + NADPH + H+ 1.1.1
–
3-trans-tetradecenoyl-CoA + NADP+ <=> 2,4-tetradecadienoyl-CoA + NADPH + H+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
M
3-Dehydroecdysone + NADPH + H+ <=> 3-Epiecdysone + NADP+ 1.1.1
–
M
UDP-N-acetyl-D-galactosamine + NADP+ + H2O <=> UDP-N-acetyl-D-galactosaminuronate + NADPH + H+ 1.1.1.136 UDP-N-acetylglucosamine 6-dehydrogenase
–
UDP-N-acetyl-6-deoxy-alpha-D-galactosamine + NADP+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose + NADPH + H+ 1.1.1
–
M
(3E)-undecenoyl_CoA + NADP+ <=> (2E,4Z)-undeca-2,4-dienoyl-CoA + NADPH + H+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
M
(3E)-undecenoyl_CoA + NADP+ <=> (2E,_4E)-undeca-2,4-dienoyl-CoA + NADPH + H+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
M
sulfonopine + NADP+ + H2O <=> S-methyl-L-methionine + pyruvate + NADPH + H+ 1.5.1
–
9-hydroxy-3,5,7,11,13,15,17,19-octaoxohenicosanoyl-[acp] + NADP+ <=> 3,5,7,9,11,13,15,17,19-nonaoxohenicosanoyl-[acp] + NADPH + H+ 1.1.1
–
M
L-ornithine + 2-oxoglutarate + NADPH + H+ <=> ornaline + NADP+ + H2O 1.5.1
–
siderophore-bound_Fe(II) + NADP+ + H+ <=> siderophore-bound_Fe(III) + NADPH 1.16.1.10 ferric-chelate reductase [NAD(P)H]
–
LysW-L-glutamate_5-semialdehyde + NADP+ + phosphate <=> [amino-group_carrier_protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + NADPH + H+ 1.2.1.38 N-acetyl-gamma-glutamyl-phosphate reductase
–
M
tetramethylpyrazine + O2 + NADPH + H+ <=> (Z)-N,N''-(but-2-ene-2,3-diyl)diacetamide + NADP+ 1.14.12
–
M
N-(3-hydroxybutan-2-yl)acetamide + NADP+ <=> N-(3-oxobutan-2-yl)acetamide + NADPH + H+ 1.1.1
–
M
aurachin_D + O2 + NADPH + H+ <=> 9''-hydroxy-aurachin_D + H2O + NADP+ 1.14.13
–
M
9''-hydroxy-aurachin_D + O2 + NADPH + H+ <=> aurachin_RE + NADP+ + H2O 1.14.13
–
M
4-[(2E,6E,10E)-3,7-dimethyldodeca-2,6,10-trien-1-yl]-2-methyl-1-oxo-3,4,4a,8a-tetrahydro-1lambda5-quinoline-3,4-diol + NADP+ <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide + NADPH + H+ not assigned
 –
M
aminopyrrolnitrin + O2 + NADPH + H+ <=> N-[2-chloro-6-(4-chloro-1H-pyrrol-3-yl)phenyl]hydroxylamine + NADP+ + H2O not assigned
 –
N-[2-chloro-6-(4-chloro-1H-pyrrol-3-yl)phenyl]hydroxylamine + NADP+ <=> 3-chloro-4-(3-chloro-2-nitrosophenyl)-1H-pyrrole + NADPH + H+ not assigned
 –
3-chloro-4-(3-chloro-2-nitrosophenyl)-1H-pyrrole + O2 + NADPH + H+ <=> 3-chloro-4-(3-chloro-2-nitrophenyl)pyrrole + H2O + NADP+ not assigned
 –
1-oleoyl-sn-glycerol_3-phosphate + NADP+ <=> 1-oleoyl-glycerone_phosphate + NADPH + H+ 1.1.1.101 acylglycerone-phosphate reductase
–
M
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> Protomycinolide_IV + CoA + CO2 + H2O + NADP+ 2.3.1
–
M
geraniol + O2 + NADPH + H+ <=> 9-hydroxygeraniol + NADP+ + H2O 1.14.13
–
Relomycin + NADP+ <=> tylosin + NADPH + H+ 1.1.1
–
CMP-5''-3-(aminopropyl)phosphonate + NADPH + O2 <=> CMP-5''-N-hydroxy-3-(aminopropyl)phosphonate + NADP+ + H2O 1.14.13
–
M
(10E,12Z)-10,12-hexadecadienoate + NADPH + H+ <=> bombykol + NADP+ + H2O 1.2.1
–
M
2-Aminobenzaldehyde + O2 + NADPH + H+ <=> Anthranil + NADP+ + H2O 1.14.13
–
M
2-Aminobenzaldehyde + O2 + NADPH <=> anthranilate + NADP+ + H2O 1.14.13
–
M
7-deoxyloganetin + O2 + NADPH + H+ <=> loganetin + H2O + NADP+ 1.14.13
–
1,2-dinitroglycerol + NADPH <=> 2-mononitroglycerol + nitrite + NADP+ 4.99.1
–
M
1-hydroxymenth-8-en-2-one + O2 + NADPH <=> 3-isopropenyl-6-oxoheptanoate + H2O + NADP+ 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
1-mononitroglycerol + NADPH <=> glycerol + nitrite + NADP+ 4.99.1
–
2-mononitroglycerol + NADPH <=> glycerol + nitrite + NADP+ 4.99.1
–
2-nonaprenylphenol + O2 + NADPH + H+ <=> 2-(all-trans-nonaprenyl)benzene-1,4-diol + H2O + NADP+ 1.14.13
–
M
oryzalexin_D + NADP+ <=> oryzalexin_A + NADPH + H+ 1.1.1
–
M
oryzalexin_B + NADP+ <=> oryzalexin_C + NADPH + H+ 1.1.1
–
M
oryzalexin_D + NADP+ <=> oryzalexin_B + NADPH + H+ 1.1.1
–
M
oryzalexin_A + NADP+ <=> oryzalexin_C + NADPH + H+ 1.1.1
–
M
gentisyl_alcohol + NADP+ <=> 2,5-dihydroxybenzaldehyde + NADPH + H+ 1.1.1
–
M
isoepoxydon + NADP+ <=> phyllostine + NADPH + H+ 1.1.1
–
M
neopatulin + NADPH + H+ <=> (E)-ascladiol + NADP+ not assigned
 –
M
(E)-ascladiol + NADP+ <=> patulin + NADPH + H+ not assigned
 –
M
quercetin + NADPH + O2 + H+ <=> gossypetin + NADP+ + H2O 1.14.99
–
M
luteolin + NADPH + O2 + H+ <=> hypolaetin + NADP+ + H2O 1.14.99
–
fusicocca-1,10(14)-diene-8beta,16-diol + NADP+ <=> 8beta-hydroxyfusicocca-1,10(14)-diene-16-al + NADPH + H+ 1.1.1
–
M
p-acetylphenyl_sulfate + NADPH + H+ + O2 <=> 4-sulfophenyl_acetate + NADP+ + H2O 1.14.13
–
M
Berberine + NADPH <=> 7,8-dihydroberberine + NADP+ not assigned
 –
M
7,8-dihydroberberine + NADPH + H+ <=> (R)-canadine + NADP+ not assigned
 –
M
S-adenosyl-L-methionine + malonyl-CoA + holo-2-methylbutanoyl-[polyketide_synthase] + NADPH + H+ <=> (S)-2-methylbutanoyl-[2-methylbutanoate_polyketide_synthase] + S-adenosyl-L-homocysteine + CO2 + CoA + H2O + NADP+ 2.3.1.244 2-methylbutanoate polyketide synthase
–
M
5,10-methylene-tetrahydromethanopterin_(iminium_form) + NADP+ <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH + H+ 1.5.1
–
(R)-1,2-Propanediol + NADP+ <=> D-Lactaldehyde + NADPH + H+ 1.1.1
–
M
(S)-1,2-Propanediol + NADP+ <=> L-lactaldehyde + NADPH + H+ 1.1.1.55 lactaldehyde reductase (NADPH)
–
M
L-Rhamnofuranose + NADP+ <=> L-Rhamno-1,4-lactone + NADPH + H+ 1.1.1.377 L-rhamnose 1-dehydrogenase (NADP+)
–
S-adenosyl-L-methionine + malonyl-CoA + acetyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> 6,8-dimethyl-3-oxo-4,6-decadienoyl-[acp] + S-adenosyl-L-homocysteine + CoA + CO2 + H2O + NADP+ 2.3.1
–
M
3,6-anhydro-L-galactose + H2O + NADP+ <=> 3,6-anhydro-L-galactonate + NADPH + H+ not assigned
 –
M
S-adenosyl-L-methionine + malonyl-CoA + acetyl-CoA + NADPH + H+ + [acyl-carrier_protein] <=> 10-methyl-3-oxo-4,6,8-dodecatrienoyl-[acp] + NADP+ + CoA + S-adenosyl-L-homocysteine + CO2 + H2O 2.3.1
–
M
S-adenosyl-L-methionine + malonyl-CoA + acetyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> 8,10-dimethyl-3-oxo-4,6,8-dodecatrienoyl-[acp] + CoA + S-adenosyl-L-homocysteine + CO2 + H2O + NADP+ 2.3.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + NADPH + H+ + [acyl-carrier_protein] <=> 4,6-dimethyl-3-oxooctanoyl-[acp] + NADP+ + CoA + S-adenosyl-L-homocysteine + H2O + CO2 2.3.1
–
M
4-aminobenzoyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> candicinolide + CoA + CO2 + H2O + NADP+ 2.3.1
–
M
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> arachidonic_acid + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> docosahexaenoic_acid + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
(8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + NADPH + H+ <=> (3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA + NADP+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
2R,3R-2,3-dihydroxy-3-methylpentanoate + NADP+ <=> (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH + H+ 1.1.1.383 ketol-acid reductoisomerase [NAD(P)+]
–
M
andiconin + O2 + NADPH + H+ <=> andilesin_D + NADP+ + H2O 1.14.13
–
M
(3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA + NADP+ <=> (11Z,14Z)-3-oxoicosadienoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(11Z,14Z)-icosa-11,14-dienoyl-CoA + NADP+ <=> (2E,11Z,14Z)-icosatrienoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
deoxybrevianamide_E + NADPH + H+ + O2 <=> 6-hydroxy-deoxybrevianamide_E + NADP+ + H2O 1.14.13
–
M
notoamide_E + NADPH + H+ + O2 <=> notoamide_D + NADP+ + H2O 1.14.13
–
M
notoamide_E + NADPH + H+ + O2 <=> notoamide_C + NADP+ + H2O 1.14.13
–
M
(3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA + NADP+ <=> (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(7Z,10Z,13Z,16Z)-Docosatetraenoyl-CoA + NADP+ <=> (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
stearoyl-CoA + O2 + NADPH + H+ <=> omega-hydroxy_fatty_acyl-CoA + NADP+ + H2O 1.14.13
–
(3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA + NADP+ <=> (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(9Z,12Z,15Z,18Z,21Z)-Tetracosapentaenoyl-CoA + NADP+ <=> (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
(3R)-hydroxy-auricoloyl-CoA + NADP+ <=> 3-oxoauricoloyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
auricoloyl-CoA + NADP+ <=> (2E,11Z,17Z)-14R-hydroxy-icosa-11,17-trienoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
GDP-6-deoxy-4-keto-D-arabino-heptose + NADPH + H+ <=> GDP-6-deoxy-D-altro-heptose + NADP+ 1.1.1
–
M
GDP-6-deoxy-4-keto-D-lyxo-heptose + NADPH + H+ <=> GDP-6-deoxy-D-manno-heptose + NADP+ 1.1.1
–
M
GDP-6-deoxy-4-keto-L-xylo-heptose + NADPH + H+ <=> GDP-6-deoxy-L-gluco-heptose + NADP+ 1.1.1
–
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> 8,10,16-trimethyl-3-oxooctadeca-4,8,12,14,16-pentaenoyl-[acp] + S-adenosyl-L-homocysteine + CoA + CO2 + NADP+ + H2O 2.3.1
–
M
8,10,16-trimethyl-3-oxooctadeca-4,8,12,14,16-pentaenoyl-[acp] + L-tryptophan + ATP + NADPH <=> prochaetoglobosin_I + [acyl-carrier_protein] + AMP + diphosphate + H2O + NADP+ 6.3.2
–
M
gliotoxin + NADPH + H+ <=> dithiolgliotoxin + NADP+ 1.8.1
–
M
Zymosterol + NADP+ <=> 26,27-dehydrozymosterol + NADPH + H+ 1.3.1
–
(-)-maackiain + NADPH + H+ + O2 <=> 1alpha-hydroxy-maackiain + NADP+ + H2O 1.14.13
–
M
medicarpin + NADPH + H+ + O2 <=> 1alpha-hydroxymedicarpin + NADP+ + H2O 1.14.13
–
M
(-)-phaseollin + NADPH + H+ + O2 <=> 1alpha-hydroxyphaseollone + NADP+ + H2O 1.14.13
–
M
CAI-1 + NADP+ <=> tridecane-3,4-dione + NADPH + H+ 1.1.1
–
M
decarboxy-demycosaminyl-nystatin + NADPH + H+ + O2 <=> demycosaminyl-nystatin + NADP+ + H2O 1.14.13
–
M
acetyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> decarboxy-dehydroxy-demycosaminyl-nystatin + CoA + CO2 + H2O + NADP+ 2.3.1
–
M
decarboxy-dehydroxy-demycosaminyl-nystatin + O2 + NADPH + H+ <=> decarboxy-demycosaminyl-nystatin + H2O + NADP+ 1.14.13
–
M
(-)-maackiain + NADPH + H+ <=> 7,2''-dihydroxy-4,5''-methylenedioxyisoflavan + NADP+ 1.1.1
–
M
7,2''-dihydroxy-4''-methoxyisoflavan + NADPH + H+ + O2 <=> 10,2''-dihydroxy-4''-methoxy-isoflav-8-ene-7-one + NADP+ + H2O 1.14.13
–
M
7,2''-dihydroxy-4,5''-methylenedioxyisoflavan + NADPH + H+ + O2 <=> 10,2''-dihydroxy-4,5''-methylenedioxy-isoflav-8-ene-7-one + NADP+ + H2O 1.14.13
–
M
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + NADP+ <=> 3-[(2Z,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate + NADPH + H+ 1.3.1.aa
–
M
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + NADP+ <=> 3-[(2E,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate + NADPH + H+ 1.3.1.aa
–
M
2,4-dinitrophenol + NADPH <=> O-[5-(oxidonitroso)-4-oxocyclohex-2-en-1-ylidenenitroso]oxidanidolate + NADP+ 1.7.1
–
M
NADP+ + H+ + e- <=> NADPH not assigned
 –
(-)-matairesinol + NADPH + H+ + O2 <=> (-)-thujaplicatin + NADP+ + H2O 1.14.13
–
M
16-hydroxypalmitoyl-CoA + NADPH + H+ <=> hexadecan-1,16-diol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
18-hydroxyoleoyl-CoA + NADPH + H+ <=> (9Z)-octadec-9-ene-1,18-diol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
18-hydroxystearoyl-CoA + NADPH + H+ <=> 1,18-octadecane-diol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
2-(2,8-dihydroxytridecyl)-6-oxopyran-4-olate + NADP+ <=> 2-(8-hydroxy-2-oxotridecyl)-6-oxopyran-4-olate + NADPH + H+ 1.1.1
–
M
7-hydroxylauroyl-CoA + NADPH + H+ <=> dodecane-1,7-diol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
omega-hydroxy_oleic_acid + NADP+ <=> 18-Oxooleate + NADPH + H+ 1.1.1
–
M
18-Oxooleate + NADP+ + H2O <=> Octadec-9-ene-1,18-dioic-acid + NADPH + H+ 1.2.1
–
M
4-methyl-proline + NADPH + H+ + O2 <=> 3-hydroxy-4-methyl-L-proline + NADP+ + H2O 1.14.13
–
M
echinocandin_D + NADPH + H+ + O2 <=> echinocandin_C + NADP+ + H2O 1.14.13
–
M
echinocandin_C + NADPH + H+ + O2 <=> Echinocandin_B + NADP+ + H2O not assigned
 –
M
6-hydroxy-3-succinoylsemialdehyde-pyridine + NADP+ + H2O <=> 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + NADPH + H+ 1.2.1
–
M
griseophenone_B + NADPH + H+ + O2 <=> desmethyl-dehydro-griseofulvin + NADP+ + H2O 1.14.19
–
M
dehydrogriseofulvin + NADPH + H+ <=> griseofulvin + NADP+ 1.3.1
–
M
(8E,10E)-dodeca-8,10-dienoate + NADPH + H+ <=> (8E,10E)-dodeca-8,10-dienol + NADP+ + H2O 1.2.1
–
M
dechloro-dehydrogriseofulvin + NADPH + H+ <=> dechlorogriseofulvin + NADP+ 1.3.1
–
M
(9Z,11E)-tetradec-9,11-dienoyl-CoA + NADPH + H+ <=> (Z9,E11)-tetradec-9,11-en-1-ol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
(Z)-11-tetradecenoyl-CoA + NADPH + H+ <=> (Z)-11-tetradecen-1-ol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
(9Z)-tetradecenoyl-CoA + NADPH + H+ <=> (Z)-9-tetradecen-1-ol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
(E)-11-tetradecenoyl-CoA + NADPH + H+ <=> (11E)-tetradecenol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
dTDP-beta-L-digitoxose + NADP+ <=> dTDP-4-dehydro-2,6-dideoxy-alpha-L-glucose + NADPH + H+ 1.1.1
–
M
12a-deshydroxy-desmethylanthrotainin + NADPH + H+ + O2 <=> desmethylanthrotainin + NADP+ + H2O 1.14.13
–
M
desmethylanthrotainin + NADPH + H+ + O2 <=> 5-hydroxy-desmethylanthrotainin + NADP+ + H2O 1.14.13
–
M
Fumiquinazoline_F + NADPH + H+ + O2 <=> fumiquinazoline_F-indoline-3''-ol + NADP+ + H2O 1.14.13
–
M
15,15-dimethyl-2-epi-fumiquinazoline_A + NADPH + H+ + O2 <=> (2R)-3-[(9S,_9aR)-9-hydroxy-2,2-dimethyl-3-oxo-1H,_2H,_3H,_9H,_9aH-imidazolidino[1,2-a]_indol-9-yl]-2-(2-acetyl-4-oxo-3,4-dihydroquinazolin-3-yl)_propanoate + NADP+ + NH3 1.14.13
–
M
deoxynortryptoquialanone + NADPH + H+ + O2 <=> tryptoquialanone + NADP+ + H2O 1.14.13
–
M
tryptoquialanone + NADPH + H+ <=> tryptoquialanol + NADP+ 1.1.1
–
M
(3R,5Z)-3-hydroxy-tetradec-5-enoyl-[acp] + NADP+ <=> (5Z)-3-oxo-tetradec-5-enoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,7Z)-3-hydroxy-hexadec-7-enoyl-[acp] + NADP+ <=> (7Z)-3-oxo-hexadec-7-enoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,9Z)-3-hydroxy-octadec-9-enoyl-[acp] + NADP+ <=> (9Z)-3-oxo-octadec-9-enoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,11Z)-3-hydroxy-icos-11-enoyl-[acp] + NADP+ <=> (11Z)-3-oxo-icos-11-enoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
S-adenosyl-L-methionine + R-Hmp-MeVal-Phe-MePhe-Pro-alle-MeVal-Leu-[acp] + ATP + L-valine + NADPH + O2 <=> R-Hmp-MeVal-Phe-MePhe-Pro-alle-MeVal-Leu-MeVal-[acp] + AMP + diphosphate + S-adenosyl-L-homocysteine + NADP+ + H2O + H+ 6.3.2
–
M
L-2-amino-8-hydroxydecanoate + NADP+ <=> L-2-amino-8-oxodecanoate + NADPH + H+ 1.1.1
–
M
L-2-aminodecanoate + NADPH + H+ + O2 <=> L-2-amino-8-hydroxydecanoate + NADP+ + H2O 1.14.13
–
M
S-adenosyl-L-methionine + malonyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> 1-[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(1E)-prop-1-en-1-yl)]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]butane-1,3-dioyl-[acp] + CoA + S-adenosyl-L-homocysteine + NADP+ + CO2 + H2O 2.3.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> (5E,7E,9E,11E,13E)-3,7,11,13-tetramethylpentadeca-5,7,9,11,13-pentaene-2,4-dioyl-[acp] + CoA + S-adenosyl-L-homocysteine + CO2 + NADP+ + H2O 2.3.1
–
M
acyl-L-alanyl-glycyl-[SfmB_peptidyl-carrier-protein] + 3O,4-dimethyl,5-hydroxy_L-tyrosyl-[SfmC_L-tyrosyl-carrier-protein] + NADPH <=> holo-[SfmB_glycyl-carrier_protein] + holo-[SfmC_tyrosyl-carrier-protein] + presaframycin + H2O + NADP+ 2.3.1
–
M
acetyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> triketide-[acp] + CoA + CO2 + H2O + NADP+ 2.3.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> (5E,7E,9E,11E,13Z)-5,9,11,13-tetramethylpentadeca-5,7,9,11,13-pentaene-2,4-dioyl-[acp] + CoA + S-adenosyl-L-homocysteine + CO2 + NADP+ + H2O 2.3.1
–
M
(5E,7E,9E,11E,13Z)-5,9,11,13-tetramethylpentadeca-5,7,9,11,13-pentaene-2,4-dioyl-[acp] + L-homoserine + ATP + NADPH <=> prefusarin + [acyl-carrier_protein] + AMP + diphosphate + NADP+ + H2O 6.3.2
–
M
prefusarin + NADPH + H+ + O2 <=> 20-hydroxy-prefusarin + NADP+ + H2O 1.14.13
–
M
20-hydroxy-prefusarin + NADPH + H+ + O2 <=> 20-hydroxy-13-14_epoxy-prefusarin + NADP+ + H2O 1.14.13
–
M
20-hydroxy-13-14_epoxy-prefusarin + NADPH + H+ + O2 <=> 20-hydroxy-fusarin + NADP+ + H2O 1.14.13
–
M
5-O-desosaminyl-tylactone + O2 + NADPH + H+ <=> 20-deoxo-20-dihydrorosamicin + NADP+ + H2O 1.14.13
–
M
20-deoxo-20-dihydrorosamicin + O2 + NADPH + H+ <=> 20-dihydrorosamicin + NADP+ + H2O 1.14.13
–
M
20-dihydrorosamicin + O2 + NADPH + H+ <=> rosamicin + NADP+ + H2O 1.14.13
–
M
(S)-2-amino-6-oxohexanoate + holo-[LYS2_L-2-aminoadipyl-carrier-protein] + NADP+ <=> L-2-aminoadipyl-[LYS2_L-2-aminoadipyl-carrier-protein] + NADPH + H+ not assigned
 –
M
L-tryptophan + O2 + NADPH + H+ <=> 9-N-hydroxy-L-tryptophan + NADP+ + H2O 1.14.13
–
M
NADP+ + reduced_acceptor <=> 1,2-dihydro-beta-NAD(P) + acceptor + H+ not assigned
 –
NADP+ + reduced_acceptor <=> 1,6-dihydro-beta-NAD(P) + acceptor + H+ not assigned
 –
arabidopaldehyde + NADPH + H+ <=> arabidopyl_alcohol + NADP+ 1.1.1
–
M
arabidopaldehyde + NADP+ + H2O <=> arabidopate + NADPH + H+ 1.2.1
–
M
iso-arabidopaldehyde + NADPH + H+ <=> iso-arabidopyl_alcohol + NADP+ 1.1.1
–
M
iso-arabidopaldehyde + NADP+ + H2O <=> iso-arabidopate + NADPH + H+ 1.2.1
–
M
S-adenosyl-L-methionine + acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 3-methylorcinaldehyde + S-adenosyl-L-homocysteine + CoA + H2O + NADP+ + CO2 2.3.1
–
M
3-methylorcinaldehyde + O2 + NADPH + H+ <=> (2R,6Z)-2-hydroxy-6-(hydroxymethylidene)-2,5-dimethylcyclohex-4-ene-1,3-dione + NADP+ + H2O 1.14.13
–
M
1,6,8-trihydroxy-1H,3H-cyclohepta[c]furan-5-one + O2 + NADPH <=> stipitalide + NADP+ + H2O 1.14.13
–
M
stipitalide + O2 + NADPH + H+ <=> stipitaldehydate + NADP+ + H2O 1.14.13
–
M
stipitaldehydate + O2 + NADPH + H+ <=> Stipitatonate + NADP+ + H2O 1.14.13
–
M
3,5,7,9,11,13,15,17,19-nonaoxohenicosanoate + H+ + NADPH + O2 <=> homo-UWM6 + CO2 + H2O + NADP+ 2.3.1
–
pentadecane-2,4,6,8,10,12,14-heptonyl-[acp] + NADPH + H+ <=> 6-O-demethylfusarubinaldehyde + [acyl-carrier_protein] + H2O + NADP+ 2.3.1
–
M
8-O-methylfusarubinaldehyde + NADPH + H+ + O2 <=> 8-O-methyl-5-hydroxy-fusarubinaldehyde + NADP+ + H2O 1.14.13
–
M
8-O-methyl-5-hydroxy-fusarubinaldehyde + NADPH + H+ + O2 <=> 8-O-methyl-5,10-dihydroxy-fusarubinaldehdye + NADP+ + H2O 1.14.13
–
M
pre-bikaverin + NADPH + H+ + O2 <=> 7-hydroxy-pre-bikaverin + NADP+ + H2O 1.14.13
–
M
7,10-diketo-pre-bikaverin + NADPH + H+ + O2 <=> 6-hydroxy-norbikaverin + NADP+ + H2O 1.14.13
–
M
7-hydroxy-pre-bikaverin + NADP+ <=> 7,10-diketo-pre-bikaverin + NADPH + H+ 1.1.1
–
M
tirandamycin_F + O2 + NADPH + H+ <=> tirandamycin_E + H2O + NADP+ 1.14.13.M7
–
tirandamycin_C + O2 + NADPH + H+ <=> tirandamycin_F + H2O + NADP+ 1.14.13.M8
–
tirandamycin_A + O2 + NADPH + H+ <=> tirandamycin_B + H2O + NADP+ 1.14.13.M9
–
guanidinoacetyl-[polyketide_synthase] + aminomalonyl-[L-seryl-carrier_protein] + malonyl-CoA + L-glutamate + NADPH + H+ <=> (2S,3S,7R)-2-amino-3-amino-7-hydroxy-8-(2-iminoimidazolidin-4-yl)octanoyl-[GdnH_polyketide_synthase] + CoA + 2-oxoglutarate + holo-[L-seryl-carrier_protein] + CO2 + H2O + NADP+ 2.3.1
–
M
Guanidinoacetate + aminomalonyl-[L-seryl-carrier_protein] + malonyl-[acyl-carrier_protein] + Carbamoyl_phosphate + H+ + NADPH + L-glutamate <=> (2S,3S,7R)-2,3-diamino-8-(1-carbamoyl-2-iminoimidazolidin-4-yl)-7-hydroxyoctanoate + [acyl-carrier_protein] + holo-[L-seryl-carrier_protein] + phosphate + CO2 + H2O + NADP+ + 2-oxoglutarate 2.3.1
–
fatty_acid + L-asparagine + L-serine + malonyl-CoA + aminomalonyl-[L-seryl-carrier_protein] + (2R)-2-hydroxymalonyl-[acp] + L-Albizziin + L-alanine + O2 + NADPH + H+ + polyketide-[acp] <=> proto-zwittermicin_A-L-alanyl-[PKS] + CO2 + NADP+ + H2O + holo-[L-seryl-carrier_protein] + [acyl-carrier_protein] + CoA 2.3.1
–
M
rubrofusarin + NADPH + H+ + O2 <=> 9-hydroxyrubrofusarin + NADP+ + H2O 1.14.13
–
M
9-hydroxyrubrofusarin + O2 + NADPH + H+ <=> dimeric_9-hydroxyrubrofusarin + NADP+ + H2O 1.14.19
–
M
dimeric_9-hydroxyrubrofusarin + NADP+ <=> aurofusarin + NADPH + H+ 1.1.1
–
M
rubrofusarin + O2 + NADPH + H+ <=> dimeric_rubrofusarin + H2O + NADP+ 1.14.19
–
M
dimeric_rubrofusarin + NADPH + H+ + O2 <=> dimeric_rubrofusarin-9-hydroxyrubrofusarin + NADP+ + H2O 1.14.13
–
M
dimeric_rubrofusarin-9-hydroxyrubrofusarin + NADP+ <=> fuscofusarin + NADPH + H+ 1.1.1
–
M
fuscofusarin + NADPH + H+ + O2 <=> dimeric_9-hydroxyrubrofusarin-fuscofusarin + NADP+ + H2O 1.14.13
–
M
dimeric_9-hydroxyrubrofusarin-fuscofusarin + NADP+ <=> aurofusarin + NADPH + H+ 1.1.1
–
M
NADPH + H+ + 2,4-dihydroxy_6-(2,4,6-trioxoheptyl)benzoyl-[acp] <=> citreoisocoumarin + [acyl-carrier_protein] + NADP+ 2.3.1
–
M
proto-zwittermicin_A-L-alanyl-[PKS] + L-leucine + L-methionine + O2 + NADPH <=> proto-zwittermicin_A + pyruvoyl-L-leucyl-L-methionine + NADP+ + H2O + polyketide-[acp] 2.3.1
–
M
3-hydroxy-4-methylbenzaldehyde + NADP+ + H2O <=> 3-hydroxy-4-methylbenzoate + NADPH + H+ 1.2.1.7 benzaldehyde dehydrogenase (NADP+)
–
M
3-hydroxy-5-methylbenzaldehyde + NADP+ + H2O <=> 3-Hydroxy-5-methylbenzoate + NADPH + H+ 1.2.1.7 benzaldehyde dehydrogenase (NADP+)
–
M
S-adenosyl-L-methionine + malonyl-CoA + acetyl-CoA + [acyl-carrier_protein] + NADPH + H+ <=> (5E,7S,9S,11,E,13E,15E)-7,9,15-trimethylheptadeca-5,11,13,15-tetraene-2,4-dionyl-[acp] + CoA + S-adenosyl-L-homocysteine + CO2 + NADP+ + H2O 2.3.1
–
M
4-hydroxy-3-methylbenzoate + O2 + NADPH + H+ <=> 4-hydroxy-3-(hydroxymethyl)benzoate + NADP+ + H2O 1.14.13.M11
–
M
L-valine + L-tryptophan + L-methionine + NADPH + H+ <=> N-methyl-L-valyl-L-tryptophanol + L-homocysteine + H2O + NADP+ 2.3.1
–
M
lyngbyatoxin_A + NADPH + O2 + H+ <=> lyngbyatoxin_B + H2O + NADP+ 1.14.13
–
M
lyngbyatoxin_A + O2 + NADPH + H+ <=> lyngbyatoxin_C + H2O + NADP+ 1.14.13
–
M
hexadecanal + [LuxE]-L-cysteine + NADP+ <=> [LuxE]-S-(long-chain_fatty_acyl)-L-cysteine + NADPH + H+ 1.2.1.50 long-chain acyl-protein thioester reductase
–
M
(3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA + NADP+ <=> (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(9Z,12Z,15Z,18Z)-Tetracosatetraenoyl-CoA + NADP+ <=> (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
3-hydroxyquinaldate + H2O + NADP+ <=> 3-hydroxykynurenate + NADPH + H+ 1.17.1
–
M
L-tryptophyl-[L-tryptophyl-carrier_protein] + O2 + NADPH + H+ <=> (S)-beta-hydroxy-L-tryptophyl-[L-tryptophyl-carrier_protein] + NADP+ + H2O 1.14.13
–
M
arachidoyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ + holo_mycolipanoate_synthase <=> C29-mycolipanoyl-[mycolipanoate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.252 mycolipanoate synthase
–
stearoyl-[mycocerosate_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> C30-mycocerosyl-[mycocerosate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.111 mycocerosate synthase
–
icosanoyl-[mycocerosate_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> C32-mycocerosyl-[mycocerosate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.111 mycocerosate synthase
–
stearoyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ + holo_mycolipanoate_synthase <=> C27-mycolipanoyl-[mycolipanoate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.252 mycolipanoate synthase
–
heptanoyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C32-mycoketide-CoA + CoA + CO2 + NADP+ + H2O 2.3.1.295 mycoketide-CoA synthase
–
behenoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + NADP+ + H2O + CO2 + CoA 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
M
C31-phthiotriol + NADP+ <=> C31-phthiodiolone_A + NADPH + H+ 1.1.1.M11
–
arachidoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + CoA + CO2 + H2O + NADP+ 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
C33-phthiotriol_A + NADP+ <=> C33-phthiodiolone_A + NADPH + H+ 1.1.1.M11
–
M
C31-phthiodiolone_A + NADP+ <=> C31-phthiodiolenone_A + NADPH + H+ 1.1.1.M10
–
C33-phthiodiolone_A + NADP+ <=> C33-phthiodiolenone_A + NADPH + H+ 1.1.1.M10
–
M
C34-phenolphthiotriol_A + NADP+ <=> C34-phenolphthiodiolone_A + NADPH + H+ 1.1.1.M11
–
M
C34-phenolphthiodiolone_A + NADP+ <=> C34-phenolphthiodiolenone_A + NADPH + H+ 1.1.1.M10
–
M
4-hydroxybenzoyl-[4-hydroxyphenylalkanoate_synthase] + malonyl-CoA + NADPH + H+ <=> 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
M
phenolphthiotriol + NADP+ <=> phenolphthiodiolone + NADPH + H+ 1.1.1.M11
–
phenolphthiodiolone + NADP+ <=> phenolphthiodiolenone + NADPH + H+ 1.1.1.M10
–
phthiotriol + NADP+ <=> a_phthiodiolone + NADPH + H+ 1.1.1.M11
–
a_phthiodiolone + NADP+ <=> phthiodiolenone + NADPH + H+ 1.1.1.M10
–
stearoyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ + holo_mycolipanoate_synthase <=> mycolipanoyl-[mycolipanoate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.252 mycolipanoate synthase
–
M
palmitoleoyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> 2-methyl-octadec-2,9-dienoate + CoA + CO2 + NADP+ 2.3.1.M8
–
a_long-chain_acyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + NADP+ + H2O + CO2 + CoA 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
C36-phenolphthiodiolone_A + NADP+ <=> C36-phenolphthiodiolenone_A + NADPH + H+ 1.1.1.M10
–
M
C36-phenolphthiotriol_A + NADP+ <=> C36-phenolphthiodiolone_A + NADPH + H+ 1.1.1.M11
–
M
medium-chain_fatty_acyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> a_mycoketide-CoA + CoA + CO2 + NADP+ + H2O 2.3.1.295 mycoketide-CoA synthase
–
M
a_palmitoyl-[(hydroxy)phthioceranic_acid_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> C37-hydroxyphthioceranyl-[(hydroxy)phthioceranate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.287 phthioceranic/hydroxyphthioceranic acid synthase
–
M
a_palmitoyl-[(hydroxy)phthioceranic_acid_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> C40-hydroxyphthioceranyl-[(hydroxy)phthioceranate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.287 phthioceranic/hydroxyphthioceranic acid synthase
–
diphenyl_ether + O2 + NADPH + H+ <=> (1S,2S)-3-phenoxycyclohexa-3,5-diene-1,2-diol + NADP+ 1.14.12.18 biphenyl 2,3-dioxygenase
–
M
3beta,7alpha,12alpha-trihydroxy-5beta-cholanoate + NADP+ <=> 7alpha,12alpha-dihydroxy-5beta-cholan-3-one-24-oic_acid + NADPH + H+ 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
–
3beta,7alpha-dihydroxy-5beta-cholanate + NADP+ <=> 7alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
–
bisphenol_A + O2 + NADPH + H+ <=> 1,2-Bis(4-hydroxyphenyl)-2-propanol + NADP+ + H2O 1.14.13.M17
–
M
bacteriopheophytin_a + NADP+ <=> geranylgeranyl_bacteriopheophytin + NADPH + H+ 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase
–
chlorophyll_a + NADP+ <=> geranylgeranyl-chlorophyll + NADPH + H+ 1.3.1.83 geranylgeranyl diphosphate reductase
–
dihydrogeranylgeranyl_bacteriochlorophyllide_b + NADP+ <=> Geranylgeranyl_bacteriochlorophyllide_b + NADPH + H+ not assigned
 –
M
Bacteriochlorophyll_b + NADP+ <=> tetrahydrogeranylgeranyl_bacteriochlorophyllide_b + NADPH + H+ not assigned
 –
M
tetrahydrogeranylgeranyl_bacteriochlorophyllide_b + NADP+ <=> dihydrogeranylgeranyl_bacteriochlorophyllide_b + NADPH + H+ not assigned
 –
M
[F-actin]-L-methionine44 + NADPH + O2 + H+ <=> [F-actin]-L-methionine44-(R)-S-oxide + NADP+ + H2O 1.14.13.225 F-actin monooxygenase
–
[F-actin]-L-methionine47 + NADPH + O2 + H+ <=> [F-actin]-L-methionine47-(R)-S-oxide + NADP+ + H2O 1.14.13.225 F-actin monooxygenase
–
butachlor + NADPH <=> Phthalate + 2,6-bis-(1,1-dimethylethyl)-4-methylphenol + NADP+ + H+ + unknown_compound not assigned
 –
Hydroxyacetone + O2 + NADPH + H+ <=> hydroxymethylene_acetate + H2O + NADP+ not assigned
 –
M
malonate + coenzyme_M + NADP+ <=> 2-carboxyethyl-CoM + NADPH + CO2 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)
–
M
2-propanol + O2 + NADPH + H+ <=> 1,2-propanediol + NADP+ + H2O 1.14.13.229 tert-butyl alcohol monooxygenase
–
2-butanol + O2 + NADPH + H+ <=> 1-Butene-3-ol + NADP+ + H2O 1.14.19.48 tert-amyl alcohol desaturase
–
2-methyl-2-butanol + O2 + NADPH + H+ <=> 2-methyl-butane-1,2-diol + NADP+ + H2O 1.14.13.M41
–
2-methyl-2-butanol + O2 + NADPH + H+ <=> 3-methyl-butane-1,3-diol + NADP+ + H2O 1.14.13.M41
–
2-methyl-2-butanol + O2 + NADPH + H+ <=> 2-methyl-butan-2,3-diol + NADP+ + H2O 1.14.13.M41
–
flavan-4-ol + NADP+ <=> flavanone + NADPH + H+ 1.1.1.234 flavanone 4-reductase
–
2-aminobenzoylacetate + O2 + NADPH + H+ <=> 2-(hydroxylamino)benzoylacetate + H2O + NADP+ 1.14.13
–
afzelechin + NADP+ <=> pelargonidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
–
(+)-epiafzelechin + NADP+ <=> pelargonidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
–
(+)-epigallocatechin + NADP+ <=> delphinidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
–
(-)-gallocatechin + NADP+ <=> delphinidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
–
tigecycline + O2 + NADPH + H+ <=> 11-hydroxytigecycline + H2O + NADP+ 1.14.13.231 tetracycline 11a-monooxygenase
–
tetracycline + O2 + NADPH <=> 3-[(2Z,4Z)-5-carbamoyl-3-(dimethylamino)-4-hydroxypenta-2,4-dien-1-yl]-1,8-dihydroxy-4-methylnaphthalene-2-carboxylate + NADP+ + H2O + CO not assigned
 –
C9-reduced_nonaketamide-[OxyC_acyl-carrier_protein] + NADP+ <=> 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC_acyl-carrier_protein] + NADPH + H+ 1.1.1.M31
–
M
dTDP-L-daunosamine + NADP+ <=> dTDP-3-amino-4-dehydro-2,3,6-trideoxy-beta-L-glucose + NADPH + H+ 1.1.1
–
M
long-chain_fatty_acyl-[mycocerosate_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> trimethylated_mycocerosyl-[mycocerosate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.111 mycocerosate synthase
–
long-chain_fatty_acyl-[mycocerosate_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> a_mycocerosyl-[mycocerosic_acid_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.111 mycocerosate synthase
–
M
tetracenomycin_A2 + O2 + NADPH + H+ <=> 4-hydroxytetracenomycin_A2 + H2O + NADP+ not assigned
 –
4-dehydro-tetracenomycin_C + NADPH + H+ <=> tetracenomycin_C + NADP+ not assigned
 –
(10bS,4aR)-oxomaritinamine + NADP+ <=> (10bS,4aR)-noroxomaritidine + NADPH + H+ 1.3.1
–
M
(10bR,4aS)-oxomaritinamine + NADP+ <=> (4aS,10bR)-8-hydroxy-9-methoxy-4,4a-dihydro-3H,6H-5,10b-ethanophenanthridin-3-one + NADPH + H+ 1.3.1
–
M
Caranine + O2 + NADPH + H+ <=> lycorine + H2O + NADP+ 1.14.13
–
M
gamma-butyrobetaine + O2 + NADPH + H+ <=> succinate_semialdehyde + trimethylamine + NADP+ + H2O 1.14.13.239 carnitine monooxygenase
–
dihydrolipoic_acid + NADP+ <=> lipoic_acid + NADPH + H+ 1.8.1
–
choline + O2 + NADPH + H+ <=> glycolaldehyde + trimethylamine + NADP+ + H2O 1.14.13.239 carnitine monooxygenase
–
4-chloronitrosobenzene + NADP+ + H2O <=> 4-chloronitrobenzene + NADPH + H+ not assigned
 –
M
2-polyprenyl-6-methoxyphenol + O2 + NADPH + H+ <=> 2-methoxy-6-polyprenyl-1,4-benzoquinol + H2O + NADP+ 1.14.13.M56
–
delta-anaerubin + NADP+ <=> anaerobilin + NADPH + H+ 1.3.1.M12
–
M
beta-anaerubin + NADP+ <=> anaerobilin + NADPH + H+ 1.3.1.M12
–
M
(3R)-hydroxymeromycolyl-[acp] + NADP+ <=> 3-oxomeromycolyl-[acp] + NADPH + H+ 1.1.1.M9
–
(2R,3S)-2-dodecyl-3-hydroxyhexadecanoate + NADP+ <=> 2-myristoylmyristic_acid + NADPH + H+ 1.1.1.412 2-alkyl-3-oxoalkanoate reductase
–
(6Z,9Z,12Z,15Z)-3-hydroxy-2-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]octadeca-6,9,12,15-tetraenoate + NADP+ <=> (6Z,9Z,12Z,15Z)-3-oxo-2-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]octadeca-6,9,12,15-tetraenoate + NADPH + H+ 1.1.1.412 2-alkyl-3-oxoalkanoate reductase
–
M
(2R,3S)-2-decyl-3-hydroxytetradecanoate + NADP+ <=> (2R)-2-decyl-3-oxotetradecanoate + NADPH + H+ 1.1.1.412 2-alkyl-3-oxoalkanoate reductase
–
(2R,3S)-2-octyl-3-hydroxydodecanoate + NADP+ <=> (2R)-2-octyl-3-oxododecanoate + NADPH + H+ 1.1.1.412 2-alkyl-3-oxoalkanoate reductase
–
(2R,3S)-2-hexyl-3-hydroxydecanoic_acid + NADP+ <=> (2R)-2-hexyl-3-oxodecanoate + NADPH + H+ 1.1.1.412 2-alkyl-3-oxoalkanoate reductase
–
[(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl_phosphate + NADP+ <=> [4-(6-methylheptanoyl)-5-oxo-2,5-dihydrofuran-3-yl]methyl_dihydrogen_phosphate + NADPH + H+ 1.3.1.113 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase
–
M
SCB1 + NADP+ <=> factor + NADPH + H+ 1.1.1.eb
–
a_(3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP+ <=> A-factor_type_gamma-butyrolactone + NADPH + H+ 1.1.1.413 A-factor type gamma-butyrolactone 1'-reductase (1S-forming)
–
M
[(3S,4R)-4-Alkanoyl-5-oxooxolan-3-yl]methyl_phosphate + NADP+ <=> (4-alkanoyl-5-oxo-2H-furan-3-yl)methyl_phosphate + NADPH + H+ 1.3.1.113 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase
–
M
IM-2_type_gamma-butyrolactone + NADP+ <=> A-factor_type_gamma-butyrolactone + NADPH + H+ 1.1.1.eb
–
M
SCB2 + NADP+ <=> 6-dehydro-SCB2 + NADPH + H+ 1.1.1.eb
–
SCB3 + NADP+ <=> 6-dehydro-SCB3 + NADPH + H+ 1.1.1.eb
–
ethionamide_S-oxide + NADPH + O2 + H+ <=> (2-ethylpyridin-4-yl)(imino)methanesulfinate + NADP+ + H2O 1.14.13
–
M
(2-ethylpyridin-4-yl)(imino)methanesulfinate + NADPH + O2 + H+ <=> 2-ethyl-4-amidopyridine + SO2 + NADP+ + H2O 1.14.13
–
M
5-methyl-N-(4-nitrophenyl)thiophene-2-carboxamide + NADPH + O2 + H+ <=> 5-methyl-N-(4-nitrophenyl)-1-oxo-1lambda4-thiophene-2-carboxamide + NADP+ + H2O 1.14.13
–
5-methyl-N-(4-nitrophenyl)-1-oxo-1lambda4-thiophene-2-carboxamide + NADPH + O2 + H+ <=> 5-methyl-N-(4-nitrophenyl)-1,1-dioxo-1lambda6-thiophene-2-carboxamide + NADP+ + H2O 1.14.13
–
2-((2-(1,3-dioxan-2-yl)ethyl)thio)-5-phenyl-1,3,4-oxadiazole + NADPH + O2 + H+ <=> 2-[2-(1,3-dioxan-2-yl)ethanesulfinyl]-5-phenyl-1,3,4-oxadiazole + NADP+ + H2O 1.14.13
–
Ethionamide + NADPH + O2 + H+ <=> 2-ethyl-4-amidopyridine + NADP+ + H2O + SO2 1.14.13
–
putrescine + O2 + NADPH + H+ <=> 2-hydroxyputrescine + H2O + NADP+ 1.14.13.M64
–
7,2,2''-trihydroxy-4,5''-methylenedioxyisoflav-3-ene + O2 + NADPH + H+ <=> (3R,4R)-7,2,4,2''-tetrahydroxy-4,5''-methylenedioxyisoflav-3-ene + H2O + NADP+ 1.14.13
–
M
ent-isokaurene + O2 + NADPH + H+ <=> ent-isokauren-2alpha-ol + H2O + NADP+ 1.14.13
–
M
4,5-dichloro-1H-pyrrole-2-carbonyl-[PltL_prolyl-carrier_protein] + malonyl-CoA + NADPH + H+ <=> 7-(4,5-dichloro-1H-pyrrol-2-yl)-3-hydroxy-5,7-dioxoheptanoyl-[PltL_prolyl-carrier_protein] + CoA + NADP+ + CO2 2.3.1
–
M
hispidin + O2 + NADPH + H+ <=> 3-hydroxyhispidin + H2O + NADP+ 1.14.13
–
M
2,4-Dibromophenol + Br- + O2 + NADPH + H+ <=> 2,4,6-tribromophenol + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
M
phytyl_diphosphate + NADPH + H+ <=> (14E,18E)-lycopadiene + NADP+ + diphosphate 2.5.1.148 lycopaoctaene synthase
–
4-hydroxypentanoyl-CoA + NADP+ <=> 4-oxopentanoyl-CoA + NADPH + H+ 1.1.1.M44
–
M
diatoxanthin + O2 + NADPH + H+ <=> diadinoxanthin + NADP+ + H2O 1.14.13
–
M
(R)-coclaurine + NADP+ <=> (4''R)-11''-hydroxy-10''-methoxy-5''-azaspiro[cyclohexane-1,2''-tricyclo[6.3.1.04,12]dodecane]-''(12''),2,5,8,10''-pentaen-4-one + NADPH + H+ not assigned
 –
M
(4''R)-11''-hydroxy-10''-methoxy-5''-azaspiro[cyclohexane-1,2''-tricyclo[6.3.1.04,12]dodecane]-''(12''),2,5,8,10''-pentaen-4-one + NADPH + O2 + H+ <=> (4''R)-10,11''-dihydroxy-5''-azaspiro[cyclohexane-1,2''-tricyclo[6.3.1.04,12dodecane]-''(12''),2,5,8,10''-pentaen-4-one + NADP+ + formaldehyde + H2O 1.14.13
–
M
amphetamine + O2 + NADPH <=> N-hydroxyamphetamine + H2O + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
N-hydroxyamphetamine + O2 + NADPH + H+ <=> (E)-N-(1-phenylpropan-2-ylidene)hydroxylamine + H2O + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
Methamphetamine + O2 + NADPH <=> N-methyl-N-[(2S)-1-phenylpropan-2-yl]hydroxylamine + H2O + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
N-methyl-N-[(2S)-1-phenylpropan-2-yl]hydroxylamine + O2 + NADPH + H+ <=> (Z)-methyl(oxido)(1-phenylpropan-2-ylidene)azanium + H2O + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
cis-vaccenoyl-CoA + NADPH + H+ <=> cis-vaccenyl_alcohol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
histamine + O2 + NADPH <=> N-hydroxyhistamine + NADP+ + H2O 1.14.13.M66
–
M
NADP+ + H+ + e- <=> NADPH not assigned
 –
pseudopaline + H2O + NADP+ <=> N-[(3S)-3-amino-3-carboxypropyl]-L-histidine + 2-oxoglutarate + NADPH + H+ 1.5.1
–
yersinopine + H2O + NADP+ <=> N-[(3S)-3-amino-3-carboxypropyl]-L-histidine + pyruvate + NADPH + H+ 1.5.1
–
S-adenosyl-L-methionine + soluble_holo-[acyl-carrier_protein] + acetyl-[acyl-carrier_protein] + malonyl-[acyl-carrier_protein] + NADPH + H+ <=> (3S,4R,6E,8R,9S)-3,9-dihydroxy-4,8-dimethyldec-6-enoyl-[acp] + CO2 + S-adenosyl-L-homocysteine + NADP+ + H2O + [acyl-carrier_protein] 2.3.1.M60
–
M
(3S,4R,6E,8R,9S)-3,9-dihydroxy-4,8-dimethyldec-6-enoyl-[acp] + malonyl-[acyl-carrier_protein] + NADPH + H+ <=> (5R,7S,8R,10E,12R,13S)-5,7,13-trihydroxy-8,12-dimethyl-3-oxotetradec-10-enoyl-[acp] + CO2 + [acyl-carrier_protein] + NADP+ 2.3.1.M61
–
M
3-hydroxypropanoyl-[acp] + malonyl-[acyl-carrier_protein] + NADPH + H+ <=> 9-hydroxynonanoyl-[acp] + CO2 + [acyl-carrier_protein] + NADP+ + H2O 2.3.1.M63
–
M
(5R,7S,8R,10E,12R,13S)-5,7,13-trihydroxy-8,12-dimethyl-3-oxotetradec-10-enoyl-[acp] + O2 + NADPH + H+ <=> (5S,6S,7R,8R,10E,12R,13S)-5,6,7,13-tetrahydroxy-8,12-dimethyl-3-oxotetradec-10-enoyl-[acp] + H2O + NADP+ 1.14.13.M68
–
M
(2E,5S,6S,7R,8R,10E,12R,13S)-5,6,7,13-tetrahydroxy-3,8,12-trimethyltetradeca-2,10-dienoyl-[acp] + O2 + NADPH + H+ <=> (2E,5S,6S,7R,8R)-5,6,7-trihydroxy-9-{3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}-3,8-dimethylnon-2-enoyl-[acp] + H2O + NADP+ 1.14.13.M69
–
M
pseudomonic_acid_A + NADP+ <=> mupirocin_F1 + NADPH + H+ 1.1.1.M51
–
M
deoxymupirocin_F + NADP+ <=> deoxymupirocin_C + NADPH + H+ 1.1.1.M50
–
M
pseudomonic_acid_C + NADP+ <=> deoxymupirocin_F + NADPH + H+ 1.1.1.M51
–
M
mupirocin_F1 + NADP+ <=> mupirocin_C1 + NADPH + H+ 1.1.1.M50
–
M
dihydroprecondylocarpine_acetate + NADP+ <=> precondylocarpine_acetate + NADPH + H+ 1.3.1.M18
–
M
(16R,19E)-isositsirikine + NADP+ <=> 19E-geissoschizine + NADPH + H+ 1.3.1.36 geissoschizine dehydrogenase
–
(16R,19Z)-isositsirikine + NADP+ <=> 19E-geissoschizine + NADPH + H+ 1.3.1.36 geissoschizine dehydrogenase
–
Stemmadenine + NADP+ <=> intermediate_II + NADPH + H+ not assigned
 –
M
intermediate_II + NADP+ <=> intermediate_I + NADPH + H+ not assigned
 –
M
(20alphaS)-19,20--dihydrovomilenine + NADP+ <=> Vomilenine + NADPH + H+ 1.3.1.M19
–
M
17-O-acetylnorajmaline + NADP+ <=> (20alphaS)-19,20--dihydrovomilenine + NADPH + H+ 1.5.1
–
M
3-hydroxy-3-phenylpropionyl-CoA + NADP+ <=> benzoylpropionyl-CoA + H+ + NADPH not assigned
 –
M
3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NADP+ <=> 4beta-methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH not assigned
 –
3beta-hydroxy-4alpha-methyl-5alpha-cholest-7-ene-4beta-carboxylate + NADP+ <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH 1.1.1.417 3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating)
–
3beta-hydroxy-4alpha-carboxy-4beta-methylsteroid + NADP+ <=> a_4alpha-methyl-3-oxosteroid + NADPH + CO2 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> 3-dehydro-4-methylzymosterol + NADPH + CO2 1.1.1.417 3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating)
–
M
4alpha-methyl-5alpha-cholesta-8-en-3-ol + NADP+ <=> 4alpha-methylzymosterol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
M
4beta-carboxy-4alpha-methyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-cholesta-8-en-3-one + NADPH + CO2 1.1.1.417 3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating)
–
M
2-(4-aminophenyl)-L-seryl-[CmlP-peptidyl-carrier-protein] + NADPH + H+ <=> (1R,2R)-2-amino-1-(4-aminophenyl)propane-1,3-diol + holo-[CmlP-peptidyl-carrier_protein] + NADP+ not assigned
 –
M
holo-[aureothin_polyketide_synthase] + 4-nitrobenzoyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> (8E,10E)-2,4,8,10-tetramethyl-11-(4-nitrophenyl)-3,5-dioxoundeca-8,10-dienoyl-[aureothin_polyketide_synthase] + CO2 + CoA + NADP+ + H2O not assigned
 –
M
holo-[spectinabilin_polyketide_synthase] + 4-nitrobenzoyl-CoA + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> (2Z,4Z,8E,10E,12E,14E)-3,5-dihydroxy-2,4,8,10,12,14-hexamethyl-15-(4-nitrophenyl)pentadeca-2,4,8,10,12,14-hexaenoyl-[spectinabilin_polyketide_synthase] + CO2 + CoA + NADP+ + H2O not assigned
 –
M
tetraketide-[rifamycin_PKS] + O2 + NADPH + H+ <=> 7-(3-amino-2,5-dihydroxyphenyl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[rifamycin_PKS] + H2O + NADP+ 1.14.13.M73
–
M
(11R)-dihydroartemisinic_alcohol + NADP+ <=> (11R)-dihydroartemisinic_aldehyde + NADPH + H+ 1.1.1
–
3-amino-5-hydroxybenzoyl-[streptovaricin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetraketide-[streptovaricin_PKS] + CoA + NADP+ + CO2 2.3.1
–
M
tetraketide-[streptovaricin_PKS] + O2 + NADPH + H+ <=> 7-(3-amino-2,5-dihydroxyphenyl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[streptovaricin_PKS] + H2O + NADP+ 1.14.13.M73
–
M
7-(5-amino-3,6-dioxocyclohexa-1,4-dien-1-yl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[streptovaricin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> undecaketide-[streptovaricin-PKS] + CoA + NADP+ + CO2 + H2O not assigned
 –
M
7-(3-amino-5-hydroxyphenyl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[ansamycin_PKS] + O2 + NADPH + H+ <=> 7-(3-amino-2,5-dihydroxyphenyl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[ansaycin_PKS] + H2O + NADP+ 1.14.13.M73
–
7-(5-amino-3,6-dioxocyclohexa-1,4-dien-1-yl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[chaxamycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> undecaketide-[chaxamycin-PKS] + CoA + NADP+ + CO2 + H2O 2.3.1
–
M
tetraketide-[chaxamycin_PKS] + O2 + NADPH + H+ <=> 7-(3-amino-2,5-dihydroxyphenyl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[chaxamycin_PKS] + H2O + NADP+ 1.14.13.M73
–
M
3-amino-5-hydroxybenzoyl-[chaxamycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetraketide-[chaxamycin_PKS] + CoA + NADP+ + CO2 2.3.1
–
M
7-(5-amino-3,6-dioxocyclohexa-1,4-dien-1-yl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[naphthomycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetradecaketide-[naphthomycin-PKS] + CoA + NADP+ + CO2 + H2O 2.3.1
–
M
tetraketide-[naphthomycin_PKS] + O2 + NADPH + H+ <=> 7-(3-amino-2,5-dihydroxyphenyl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[naphthomycin_PKS] + H2O + NADP+ 1.14.13.M73
–
M
3-amino-5-hydroxybenzoyl-[naphthomycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetraketide-[naphthomycin_PKS] + CoA + NADP+ + CO2 2.3.1
–
M
3-amino-5-hydroxybenzoyl-[ansatrienin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> nonaketide-[ansatrienin_PKS] + CoA + NADP+ + CO2 + H2O 2.3.1.M77
–
M
(3R)-3-hydroxyoctacosanoyl-CoA + NADP+ <=> 3-oxooctacosanoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
octacosanoyl-CoA + NADP+ <=> trans-octacos-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
(3R)-3-hydroxytriacontanoyl-CoA + NADP+ <=> 3-oxotriacontanoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
melissoyl-CoA + NADP+ <=> trans-triaconta-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
(3R)-3-hydroxydotriacontanoyl-CoA + NADP+ <=> 3-oxodotriacontanoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
dotriacontanoyl-CoA + NADP+ <=> trans-dotriaconta-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
(3R)-3-hydroxytetratriacontanoyl-CoA + NADP+ <=> 3-oxotetratriacontanoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
tetratriacontanoyl-CoA + NADP+ <=> trans-tetratriaconta-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
(3R)-3-hydroxyhexatriacontanoyl-CoA + NADP+ <=> 3-oxohexatriacontanoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
hexatriacontanoyl-CoA + NADP+ <=> trans-hexatriaconta-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
(3R,15Z)-3-hydroxytetracos-15-enoyl-CoA + NADP+ <=> (15Z)-3-oxotetracos-15-enoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(15Z)-tetracosenoyl-CoA + NADP+ <=> (2E,15Z)-tetracos-2,15-dienoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
(3R,13Z)-3-hydroxydocos-13-enoyl-CoA + NADP+ <=> 3-oxo-erucoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
erucoyl-CoA + NADP+ <=> (2E,13Z)-docos-2,13-dienoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
(4R,5R)-4,5-dihydroxycyclohex-2-ene-1-carbonyl-CoA + NADP+ <=> (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carbonyl-CoA + NADPH + H+ 1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+)
–
M
(3S)-3-hydroxycyclohexane-1-carbonyl-CoA + NADP+ <=> (5S)-5-hydroxycyclohex-1-ene-1-carbonyl-CoA + NADPH + H+ 1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+)
–
M
31-norcycloartanol + NADP+ <=> 31-norcycloartanone + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
M
4alpha-methyl-5alpha-cholesta-8-en-3-ol + NADP+ <=> 4alpha-methyl-cholesta-8,14-dienol + NADPH + H+ 1.3.1.70 Delta14-sterol reductase
–
M
5alpha-Cholest-7-en-3beta-ol + NADP+ <=> 5alpha-cholest-7-en-3-one + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
M
4alpha-methyl_ergosta-8,25(27)-dienol + NADP+ <=> 4alpha-methyl_ergosta-8,14,25(27)-trienol + NADPH + H+ 1.3.1.70 Delta14-sterol reductase
–
M
S-adenosyl-L-methionine + guanidinoacetyl-[polyketide_synthase] + malonyl-CoA + NADPH + H+ <=> (2E)-4-guanidino-2-methyl-but-2-enoyl-[CyrB_PKS] + CO2 + S-adenosyl-L-homocysteine + CoA + H2O + NADP+ 2.3.1
–
M
(2E)-4-guanidino-2-methyl-but-2-enoyl-[CyrB_PKS] + malonyl-CoA + NADPH + H+ <=> (4E,6E,9S,10E)-12-guanidino-9-hydroxy-10-methyl-3-oxododeca-4,6,10-trienoyl-[CyrF_PKS] + CO2 + CoA + H2O + NADP+ 2.3.1
–
M
holo_[BryA_polyketide_synthase] + 3-phospho-D-glycerate + NADPH + H+ <=> D-lactyl-[BryA_polyketide_synthase] + phosphate + H2O + NADP+ not assigned
 –
M
malonyl-[BryP_acyl-carrier_protein] + D-lactyl-[BryA_polyketide_synthase] + NADPH + H+ <=> (5R,7R,8R)-5,7,8-trihydroxy-3-oxononanoyl-[BryA_polyketide_synthase] + CO2 + holo_[BryP_acyl-carrier_protein] + NADP+ 2.3.1
–
M
malonyl-[BryP_acyl-carrier_protein] + (3E,5S,7R,8R)-5,7,8-trihydroxy-3-(2-methoxy-2-oxoethylidene)nonanoyl-[BryA_polyketide_synthase] + holo_[BryB_polyketide_synthase] + S-adenosyl-L-methionine + NADPH + H+ <=> (5S,6E,11E,13S,15R,16R)-5,13,15,16-tetrahydroxy-11-(2-methoxy-2-oxoethylidene)-8,8-dimethyl-3,9-dioxoheptadec-6-enoyl-[BryB_polyketide_synthase] + holo_[BryP_acyl-carrier_protein] + holo_[BryA_polyketide_synthase] + S-adenosyl-L-homocysteine + CO2 + NADP+ + H2O 2.3.1
–
M
malonyl-[BryP_acyl-carrier_protein] + (3E,6E,11E,13S,15R,16R)-5,13,15,16-tetrahydroxy-3,11-di(2-methoxy-2-oxoethylidene)-8,8-dimethyl-9-oxoheptadec-2,6-dienoyl-[BryB_polyketide_synthase] + holo_[BryC_polyketide_synthase] + NADPH + H+ <=> (2E,5Z,7S,8E,13E,15S,17R,18R)-7,15,17,18-tetrahydroxy-5,13-bis(2-methoxy-2-oxoethylidene)-10,10-dimethyl-11-oxononadeca-2,8-dienoyl-[BryC_PKS] + holo_[BryP_acyl-carrier_protein] + CO2 + holo_[BryB_polyketide_synthase] + H2O + NADP+ 2.3.1
–
M
malonyl-[BryP_acyl-carrier_protein] + 4-[(4Z)-4-(2-methoxy-2-oxoethylidene)-6-[(1E,6E)-8-methoxy-3,3-dimethyl-4,8-dioxo-6-[(2S,4R,5R)-2,4,5-trihydroxyhexyl]octa-1,6-dien-1-yl]oxan-2-yl]-2,2-dimethyl-3-oxobutanoyl-[BryC_PKS] + NADPH + H+ <=> 5-hydroxy-8-[(4Z)-4-(2-methoxy-2-oxoethylidene)-6-[(1E,6E)-8-methoxy-3,3-dimethyl-4,8-dioxo-6-[(2S,4R,5R)-2,4,5-trihydroxyhexyl]octa-1,6-dien-1-yl]oxan-2-yl]-6,6-dimethyl-3,7-dioxooctanoyl-[BryC_PKS] + CO2 + holo_[BryP_acyl-carrier_protein] + NADP+ 2.3.1
–
M
malonyl-[BryP_acyl-carrier_protein] + 5-hydroxy-8-[(4Z)-4-(2-methoxy-2-oxoethylidene)-6-[(1E,6E)-8-methoxy-3,3-dimethyl-4,8-dioxo-6-[(2S,4R,5R)-2,4,5-trihydroxyhexyl]octa-1,6-dien-1-yl]oxan-2-yl]-6,6-dimethyl-3,7-dioxooctanoyl-[BryC_PKS] + holo_[BryD_polyketide_synthase] + NADPH + H+ <=> 3,5,7-trihydroxy-10-[(4Z)-4-(2-methoxy-2-oxoethylidene)-6-[(1E,6E)-8-methoxy-3,3-dimethyl-4,8-dioxo-6-[(2S,4R,5R)-2,4,5-trihydroxyhexyl]octa-1,6-dien-1-yl]oxan-2-yl]-8,8-dimethyl-9-oxodecanoyl-[BryD_PKS] + holo_[BryP_acyl-carrier_protein] + holo_[BryC_polyketide_synthase] + CO2 + NADP+ 2.3.1
–
M
malonyl-[PedD_acyl-carrier_protein] + S-adenosyl-L-methionine + 2-{2-[(2R,5R,6R)-2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamido}acetyl-[PedF_polyketide_synthase] + NADPH + H+ <=> (2E,5R,7S)-5,7-dihydroxy-8-{2-[(2R,5R,6R)-2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamido}-4,4-dimethyloct-2-enoyl-[PedF_polyketide_synthase] + holo_[PedD_acyl-carrier_protein] + CO2 + S-adenosyl-L-homocysteine + H2O + NADP+ not assigned
 –
M
malonyl-[PedD_acyl-carrier_protein] + (2E,5R,7S)-5,7-dihydroxy-8-{2-[(2R,5R,6R)-2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamido}-4,4-dimethyloct-2-enoyl-[PedF_polyketide_synthase] + NADPH + H+ <=> (3S)-3-hydroxy-4-[(4R,6S)-4-hydroxy-6-({2-[(2R,5R,6R)-2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamido}methyl)-3,3-dimethyloxan-2-yl]butanoyl-[PedF_polyketide_synthase] + holo_[PedD_acyl-carrier_protein] + CO2 + NADP+ not assigned
 –
M
(3S)-3-hydroxy-4-[(4R,6S)-4-hydroxy-6-({2-[(2R,5R,6R)-2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamido}methyl)-3,3-dimethyloxan-2-yl]butanoyl-[PedF_polyketide_synthase] + O2 + NADPH + H+ <=> holo_[PedF_polyketide_synthase] + pederin_precursor + CO2 + NADP+ 1.14.13
–
M
acetyl-CoA + malonyl-[PedD_acyl-carrier_protein] + holo_[PedI_polyketide_synthase] + S-adenosyl-L-methionine + NADPH + H+ <=> (4S,5R)-5-hydroxy-4-methyl-3-oxohexanoyl-[PedI_polyketide_synthase] + CoA + holo_[PedD_acyl-carrier_protein] + CO2 + S-adenosyl-L-homocysteine + NADP+ not assigned
 –
M
2-[(2R,5R,6R)-2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetyl-[PedI_polyketide_synthase] + malonyl-[PedD_acyl-carrier_protein] + holo_[PedF_polyketide_synthase] + S-adenosyl-L-methionine + NADPH + ATP + glycine + H+ <=> (3S)-3-hydroxy-4-[(4R,6S)-4-hydroxy-6-({2-[(2R,5R,6R)-2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamido}methyl)-3,3-dimethyloxan-2-yl]butanoyl-[PedF_polyketide_synthase] + holo_[PedI_polyketide_synthase] + holo_[PedD_acyl-carrier_protein] + CO2 + S-adenosyl-L-homocysteine + H2O + NADP+ + AMP + diphosphate 2.3.1.M81
–
tomatid-3-one + NADP+ <=> tomatid-4-en-3-one + NADPH + H+ not assigned
 –
M
dehydrotomatidine + NADP+ <=> tomatid-4-en-3-one + NADPH + H+ not assigned
 –
M
solasodine + NADP+ <=> solasod-4-en-3-one + NADPH + H+ not assigned
 –
M
solasod-3-one + NADP+ <=> solasod-4-en-3-one + NADPH + H+ not assigned
 –
M
soladulcidine + NADP+ <=> solasod-3-one + NADPH + H+ not assigned
 –
M
ursodeoxycholate_methyl_ester + NADP+ <=> 7-oxolithocholic_acid_methyl_ester + NADPH + H+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
citronellol + NADP+ <=> geraniol + NADPH + H+ 1.1.1
–
siderophore + NADP+ + Fe2+ <=> siderophore-bound_Fe(III) + NADPH + H+ 1.16.1.10 ferric-chelate reductase [NAD(P)H]
–
siderophore-bound_Fe(II) + NADP+ + H+ <=> siderophore-bound_Fe(III) + NADPH 1.16.1.10 ferric-chelate reductase [NAD(P)H]
–
(3R)-3-hydroxyoctadecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxooctadecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.86 fatty-acyl-CoA synthase system
–
M
2-(3-hydroxy-2-oxo-1H-indol-3-yl)acetate + O2 + NADPH <=> catechol + NADP+ not assigned
 –
M
(R,R)-chrysanthemal + NADP+ + H2O <=> (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylic_acid + NADPH + H+ 1.2.1
–
M
4-hydroxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one + NADPH + H+ <=> (E)-5,6-dihydro-4-hydroxy-6-(styryl)pyran-2-one + NADP+ 1.3.1.M26
–
M
4-decanone + NADPH + H+ + O2 <=> hexyl_butanoate + NADP+ + H2O 1.14.13.M76
–
3-decanone + NADPH + H+ + O2 <=> heptyl_propanoate + NADP+ + H2O 1.14.13.M76
–
3-decanone + NADPH + H+ + O2 <=> ethyl_caprylate + NADP+ + H2O 1.14.13.M76
–
2-decanone + NADPH + H+ + O2 <=> octyl_acetate + NADP+ + H2O 1.14.13.M76
–
phenylarsenite + O2 + NADPH <=> Phenylarsonate + NADP+ + H2O 1.20.1.M1
–
O2 + methylarsonite + NADPH <=> H2O + methylarsonate + NADP+ 1.20.1.M1
–
1-naphthol + O2 + NADPH + H+ <=> 1,2-dihydroxynaphthalene + H2O + NADP+ 1.14.13.M78
–
M
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 7-methylmellein + CoA + CO2 + H2O + NADP+ 2.3.1.M91
–
M
7-methylmellein + O2 + NADPH + H+ <=> 7-carboxymellein + H2O + NADP+ 1.14.13.M79
–
M
malonyl-CoA + myristoyl-D-asparaginyl-L-alanyl-[ClbB_polyketide_synthase] + NADPH + H+ <=> myristoyl-D-asparaginyl-butan-2-aminyl-acetyl-[ClbB_polyketide_synthase] + CoA + CO2 + H2O + NADP+ not assigned
 –
M
myristoyl-D-asparaginyl-butan-2-aminyl-malonyl-1-aminocyclopropane-1-carboxyl-acetyl-aminomethyl-4,5-dihydro-1,3-thiazole-4-carboxyl-[ClbJ_non-ribosomal_peptide_synthase] + aminomalonyl-[ClbK_polyketide_synthase] + NADP+ <=> myristoyl-D-asparaginyl-butan-2-aminyl-malonyl-1-aminocyclopropane-1-carboxyl-acetyl-aminomethyl-1,3-thiazole-4-carboxy-glycyl-[ClbK_polyketide_synthase] + holo_[ClbJ_non-ribosomal_peptide_synthase] + CO2 + NADPH + H+ not assigned
 –
M
myristoyl-D-asparaginyl-butan-2-aminyl-malonyl-1-aminocyclopropane-1-carboxyl-acetyl-aminomethyl-1,3-thiazole-4-carboxy-glycyl-[ClbK_polyketide_synthase] + L-cysteinyl-[ClbK_polyketide_synthase] + NADP+ <=> myristoyl-D-asparaginyl-butan-2-aminyl-malonyl-1-aminocyclopropane-1-carboxyl-acetyl-aminomethyl-1,3-thiazole-4-carboxy-2-(aminomethyl)-1,3-thiazole-4-carboxyl-[ClbK_polyketide_synthase] + holo_[ClbK_polyketide_synthase] + H2O + NADPH + H+ not assigned
 –
M
18-hydroxyoleoyl-CoA + NADP+ <=> 18-oxo-oleoyl-CoA + NADPH + H+ 1.1.1
–
18-oxo-oleoyl-CoA + NADP+ + H2O <=> (9Z)-17-carboxyheptadec-9-enoyl-CoA + NADPH + H+ 1.2.1
–
NADP+ + H+ + e- <=> NADPH not assigned
 –
electron-transfer_quinone + H+ + NADPH <=> H+ + electron-transfer_quinol + NADP+ 7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
–
divinyl_chlorophyllide_a + O2 + NADPH + H+ <=> chlorophyllide_b2 + H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
divinyl_chlorophyllide_a + O2 + NADPH + H+ <=> 71-hydroxychlorophyllide_a2 + H2O + NADP+ not assigned
 –
M
71-hydroxychlorophyllide_a2 + O2 + NADPH + H+ <=> 71-dihydroxychlorophyllide_a2 + H2O + NADP+ not assigned
 –
M
71-hydroxychlorophyll_a2 + NADP+ <=> chlorophyll_b2 + NADPH 1.1.1.294 chlorophyll(ide) b reductase
–
(8S)-8-amino-7-oxononanoate + a_[protein]-L-tyrosine + NADPH <=> [protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + H2O + NADP+ not assigned
 –
M
[protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + CO2 + H2O + NADP+ <=> (7R,8S)-8-amino-7-(carboxyamino)nonanoate + [protein]-(S)-2-amino-6-oxohexanoate + H+ + NADPH not assigned
 –
M
N,N-dimethyl-N''-phenylurea_compound + NADPH + O2 + H+ <=> N-methyl-N''-phenylurea_compound + formaldehyde + NADP+ + H2O 1.14.13.ey
–
isoproturon + NADPH + O2 + H+ <=> N-methyl-N''-[4-(propan-2-yl)phenyl]urea + formaldehyde + NADP+ + H2O 1.14.13.ey
–
chlorotoluron + NADPH + O2 + H+ <=> N''-(3-chloro-4-methylphenyl)-N-methylurea + formaldehyde + NADP+ + H2O 1.14.13.ey
–
metoxuron + NADPH + O2 + H+ <=> N''-(3-chloro-4-methoxylphenyl)-N-methylurea + formaldehyde + NADP+ + H2O 1.14.13.ey
–
monuron + NADPH + O2 + H+ <=> N''-(4-chlorophenyl)-N-methylurea + formaldehyde + NADP+ + H2O 1.14.13.ey
–
Diuron + NADPH + O2 + H+ <=> N''-(3,4-dichlorophenyl)-N-methylurea + formaldehyde + NADP+ + H2O 1.14.13.ey
–
fluometuron + NADPH + O2 + H+ <=> N''-[3-(trifluoromethyl)phenyl]-N-methylurea + formaldehyde + NADP+ + H2O 1.14.13.ey
–
fenuron + NADPH + O2 + H+ <=> N-methyl-N''-phenylurea + formaldehyde + NADP+ + H2O 1.14.13.ey
–
CDP-6-deoxy-alpha-D-gulose + NADP+ <=> CDP-4-dehydro-6-deoxy-alpha-D-gulose + NADPH + H+ 1.1.1
–
M
dehydrotomatidine + NADP+ <=> tomatid-5-en-3-one + NADPH + H+ not assigned
 –
3-geranyl-4-hydroxybenzoate + O2 + NADPH + H+ <=> 3,4-dihydroxy-5-all-trans-polyprenylbenzoate + H2O + NADP+ 1.14.13.M81
–
L-arabinose + NADP+ <=> L-arabinono-1,4-lactone + NADPH + H+ 1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
–
(3R)-3-hydroxy-L-glutamine + O2 + NADPH + H+ <=> (3R)-3,N5-dihydroxy-L-glutamine + H2O + NADP+ 1.14.13
–
M
(4S,8R)-2,19-dihydroxy-7,9-dioxapentacyclo[10.8.0.03,10.04,8.04,19]icosa-1,3(10),5,11,14,16-hexaene-13,18,20-trione + O2 + NADPH + H+ <=> (4S,8R)-2,20-dihydroxy-7,9,13-trioxapentacyclo[10.9.0.03,10.04,8.015,20]henicosa-1,3(10),5,11,15,17-hexaene-14,19,21-trione + H2O + NADP+ not assigned
 –
M
(4S,8R)-2,13,16,20-tetrahydroxy-7,9-dioxapentacyclo[10.8.0.03,10.04,8.04,19]icosa-1(12),2,5,10,13,16,19-heptaen-18-one + NADPH + H+ <=> (4S,8R,16R)-2,13,16,20-tetrahydroxy-7,9-dioxapentacyclo[10.8.0.03,10.04,8.014,19]icosa-1(12),2,5,10,13,19-hexaen-18-one + NADP+ 1.3.1
–
M
3,8,9,10-tetrahydroxy-6-methyl-1,4-dihydroanthracen-1-one + NADPH + H+ <=> (3R)-3-hydroxy-3,4-dihydroanthracen-1(2H)-one + NADP+ 1.3.1
–
tuberculostearate + NADP+ <=> 10-methylideneoctadecanoate + NADPH + H+ 1.3.1
–
M
(4S,3R)-3-hydroxy-4-methylhexanoyl-[acp] + NADP+ <=> (4S)-4-methyl-3-oxohhexanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,6S)-3-hydroxy-6-methyloctanoyl-[acp] + NADP+ <=> (6S)-6-methyl-3-oxooctanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,8S)-3-hydroxy-8-methyldecanoyl-[acp] + NADP+ <=> (8S)-8-methyl-3-oxodecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,10S)-3-hydroxy-10-methyldodecanoyl-[acp] + NADP+ <=> (10S)-10-methyl-3-oxododecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,12S)-3-hydroxy-12-methyltetradecanoyl-[acp] + NADP+ <=> (12S)-12-methyl-3-oxotetradecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,14S)-3-hydroxy-14-methylhexadecanoyl-[acp] + NADP+ <=> (14S)-14-methyl-3-oxohexadecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(4S)-4-methylhexanoyl-[acp] + NADP+ <=> (2E,4S)-4-methylhex-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(6S)-6-methyloctanoyl-[acp] + NADP+ <=> (2E,6S)-6-methyloct-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(8S)-8-methyldecanoyl-[acyl-carrier_protein] + NADP+ <=> (2E,8S)-8-methyldec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(10S)-10-methyldodecanoyl-[acp] + NADP+ <=> (2E,10S)-10-methyldodec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(12S)-12-methyltetradecanoyl-[acp] + NADP+ <=> (2E,12S)-12-methyltetradec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(14S)-14-methylhexadecanoyl-[acp] + NADP+ <=> (2E,14S)-14-methylhexadec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-5-methylhexanoyl-[acp] + NADP+ <=> 5-methyl-3-oxohexanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
5-methylhexanoyl-[acp] + NADP+ <=> (2E)-5-methylhex-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-7-methyloctanoyl-[acp] + NADP+ <=> 7-methyl-3-oxooctanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
7-methyloctanoyl-[acp] + NADP+ <=> (2E)-7-methyloct-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-9-methyldecanoyl-[acp] + NADP+ <=> 9-methyl-3-oxodecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
9-methyldecanoyl-[acyl-carrier_protein] + NADP+ <=> (2E)-9-methyldec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-11-methyldodecanoyl-[acp] + NADP+ <=> 11-methyl-3-oxododecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
11-methyldodecanoyl-[acp] + NADP+ <=> (2E)-11-methyldodec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-13-methyltetradecanoyl-[acp] + NADP+ <=> 13-methyl-3-oxotetradecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
13-methyltetradecanoyl-[acp] + NADP+ <=> (2E)-13-methyltetradec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-15-methylhexadecanoyl-[acp] + NADP+ <=> 15-methyl-3-oxohexadecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
15-methylhexadecanoyl-[acp] + NADP+ <=> (2E)-15-methylhexadec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-4-methylpentanoyl-[acp] + NADP+ <=> 4-methyl-3-oxopentanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
5-methylhexanoyl-[acp] + NADP+ <=> (2E)-4-methylpent-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-6-methylheptanoyl-[acp] + NADP+ <=> 6-methyl-3-oxoheptanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
6-methylheptanoyl-[acp] + NADP+ <=> (2E)-6-methylhept-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-8-methylnonanoyl-[acp] + NADP+ <=> 8-methyl-3-oxononanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
8-methylnonanoyl-[acyl-carrier_protein] + NADP+ <=> (2E)-8-methylnon-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-10-methylundecanoyl-[acp] + NADP+ <=> 1o-methyl-3-oxoundecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
10-methylundecanoyl-[acp] + NADP+ <=> (2E)-10-methylundec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-12-methyltridecanoyl-[acp] + NADP+ <=> 12-methyl-3-oxotridecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
12-methyltridecanoyl-[acp] + NADP+ <=> (2E)-12-methyltridec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxy-14-methylpentadecanoyl-[acp] + NADP+ <=> 14-methyl-3-oxopentadecanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
14-methylpentadecanoyl-[acp] + NADP+ <=> (2E)-14-methylpentadec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
M
(3R)-3-hydroxyicosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxoicosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.86 fatty-acyl-CoA synthase system
–
M
icosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-icos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.86 fatty-acyl-CoA synthase system
–
M
(3R)-3-hydroxydocosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxodocosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.86 fatty-acyl-CoA synthase system
–
M
docosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-docos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.86 fatty-acyl-CoA synthase system
–
M
3-Amino-4-hydroxybenzoic_acid + O2 + NADPH + H+ <=> 3-amino-2,4-dihydroxybenzoate + H2O + NADP+ 1.14.13.M82
–
M
(7R,11S,16S)-7-hydroxy-ent-kauran-11,16-epoxy-19-oate + NADP+ <=> (11S,16S)-7-oxo-ent-kauran-11,16-epoxy-19-oate + NADPH + H+ not assigned
 –
M
(E)-4-(methylsulfanyl)butanal_oxime + NADPH + O2 + L-cysteine + H+ <=> S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine + NADP+ + H2O not assigned
 –
glucoiberverin + O2 + NADPH + H+ <=> glucoiberin + NADP+ + H2O 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
M
acetyl-CoA + oxidized_electron_transfer_flavoprotein + NADPH + CO2 + H+ <=> glyoxylate + propionyl-CoA + CoA + reduced_flavodoxin + NADP+ not assigned
 –
M
H+ + L-canaline + NADPH <=> L-homoserine + NH3 + NADP+ 1.6.6
–
M
(3R,4R)-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3,4-dihydro-2H-chromene-4,7-diol + NADP+ <=> (3R)2',7-dihydroxy-dihydro-4',5'-methylenedioxyisoflavone + NADPH + H+ 1.1.1.348 (3R)-2'-hydroxyisoflavanone reductase
–
M
isofucosterol + NADP+ <=> DELTA5,7-avenasterol + NADPH + H+ 1.3.1.21 7-dehydrocholesterol reductase
–
M
H+ + Delta24-25-sitosterol + NADPH <=> sitosterol + NADP+ not assigned
 –
M
campesterol + NADP+ <=> H+ + crinosterol + NADPH 1.3.1
–
M
(3R,4R)-7,2,4''-trihydroxyisoflavanol + NADP+ <=> (3R)-2''-hydroxydihydrodaidzein + NADPH + H+ 1.1.1.348 (3R)-2'-hydroxyisoflavanone reductase
–
M
H+ + phaseollidin + NADPH + O2 <=> (-)-phaseollin + NADP+ + H2O not assigned
 –
M
[amino-group_carrier_protein]-C-terminal-[N-(1-carboxy-5-oxopentyl)-L-glutamine] + NADP+ + phosphate <=> [amino-group_carrier_protein]-C-terminal-{N-[1-carboxy-5-oxo-5-(phosphooxy)pentyl]-L-glutamine} + NADPH + H+ 1.2.1.103 [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase
–
M
NADP+ + divinyl_chlorophyllide_a <=> divinyl_protochlorophyllide_a + NADPH + H+ + light 1.3.1.33 protochlorophyllide reductase
–
M
UDP-glucose + NADPH + H+ <=> UDP-L-rhamnose + NADP+ + H2O not assigned
 –
Indole-3-acetaldehyde + NADP+ + H2O <=> indole-3-acetic_acid + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
M
H+ + alpha-carotene + NADPH + O2 <=> zeinoxanthin + NADP+ + H2O 1.14.99
–
M
(3R)-3-hydroxy-4-oxobutanoate + NADP+ + H2O <=> (S)-malate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
–
M
1,3-diaminopropane + O2 + NADPH <=> N-(3-aminopropyl)hydroxylamine + H2O + NADP+ 1.14.13.M65
–
M
24-methylene_cholesterol + NADP+ <=> 5-dehydroepisterol + NADPH + H+ 1.3.1.21 7-dehydrocholesterol reductase
–
M
H+ + 24-methyldesmosterol + NADPH <=> campesterol + NADP+ 1.3
–
M
H+ + 2,3-dehydrokievitone + NADPH <=> Kievitone + NADP+ not assigned
 –
M
H+ + 2,4,6-trihydroxybenzophenone + O2 + NADPH <=> 2,3',4,6-tetrahydroxybenzophenone + NADP+ + H2O not assigned
 –
M
2,3',4,6-tetrahydroxybenzophenone + NADPH + O2 <=> 1,3,7-trihydroxyxanthone + NADP+ + H2O not assigned
 –
M
2,3',4,6-tetrahydroxybenzophenone + NADPH + O2 <=> 1,3,5-trihydroxyxanthone + NADP+ + H2O not assigned
 –
M
H+ + 1,3,7-trihydroxyxanthone + NADPH + O2 <=> norathyriol + NADP+ + H2O not assigned
 –
M
H+ + 1,3,5-trihydroxyxanthone + NADPH + O2 <=> 1,3,5,8-tetrahydroxyxanthone + NADP+ + H2O not assigned
 –
M
H+ + 1,3,5-trihydroxyxanthone + NADPH + O2 <=> 1,3,5,6-tetrahydroxyxanthone + NADP+ + H2O not assigned
 –
M
Gibberellin_A36 + O2 + 2-oxoglutarate + NADP+ <=> gibberellin_a4 + succinate + CO2 + NADPH 1.14.11
–
M
dihydrogeranylgeranyl_chlorophyll_a + NADP+ <=> geranylgeranyl-chlorophyll + NADPH + H+ not assigned
 –
M
tetrahydrogeranylgeranyl_chlorophyll_a + NADP+ <=> dihydrogeranylgeranyl_chlorophyll_a + NADPH + H+ not assigned
 –
M
chlorophyll_a + NADP+ <=> tetrahydrogeranylgeranyl_chlorophyll_a + NADPH + H+ not assigned
 –
M
7-hydroxychlorophyllide_a + O2 + NADPH + H+ <=> 71-dihydroxychlorophyllide_a + H2O + NADP+ not assigned
 –
M
a_very-long-chain_(3R)-3-hydroxyacyl-CoA + NADP+ <=> very-long-chain_oxoacyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
very-long-chain_2,3,4-saturated_fatty_acyl_CoA + NADP+ <=> very-long-chain_(2E)-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
M
H+ + coumarin + NADPH <=> dihydrocoumarin + NADP+ 1.3
–
M
psoralen + NADPH + O2 + H+ <=> bergaptol + NADP+ + H2O not assigned
 –
M
4-(4-hydroxyphenyl)butan-2-one + NADP+ <=> H+ + 4-hydroxybenzalacetone + NADPH 1.3.1
–
M
H+ + abieta-8(14),12-diene + NADPH + O2 <=> levopimaradienol + NADP+ + H2O 1.14.13
–
M
H+ + neoabietadiene + NADPH + O2 <=> neoabietadienol + NADP+ + H2O 1.14.13
–
M
H+ + neoabietadienol + NADPH + O2 <=> neoabietadiene-diol + NADP+ + H2O 1.14.13
–
M
neoabietadienal + NADPH + O2 <=> Neoabietate + NADP+ + H2O 1.14.13
–
M
H+ + palustradiene + NADPH + O2 <=> Palustradienol + NADP+ + H2O 1.14.13
–
M
H+ + Palustradienol + NADPH + O2 <=> palustradiene-diol + NADP+ + H2O 1.14.13
–
M
Palustradienal + NADPH + O2 <=> Palustrate + NADP+ + H2O 1.14.13
–
M
H+ + abieta-8,11,13-triene + NADPH + O2 <=> dehydroabietadienol + NADP+ + H2O 1.14.13
–
M
H+ + isopimara-7,15-diene + NADPH + O2 <=> isopimara-7,15-dienol + NADP+ + H2O 1.14.13
–
M
H+ + (3R,6E)-nerolidol + NADPH + O2 <=> (3E)-4,8-dimethylnona-1,3,7-triene + 3-buten-2-one + NADP+ + H2O 1.14.13
–
M
Hydroxyacetone + O2 + NADPH <=> acetate + formaldehyde + H2O + NADP+ 1.14.13.M34
–
L-arabinose + NADP+ <=> L-arabinono-1,4-lactone + NADPH + H+ 1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
–
M
D-arabinofuranose + NADP+ <=> D-arabinono-1,4-lactone + NADPH + H+ 1.1.1
–
M
phyta-2,10,14-trienyl_bacteriochlorophyllide_a + NADP+ <=> geranylgeranyl-bacteriochlorophyllide_a + NADPH + H+ not assigned
 –
M
phyta-2,14-dienyl_bacteriochlorophyllide_a + NADP+ <=> phyta-2,10,14-trienyl_bacteriochlorophyllide_a + NADPH + H+ not assigned
 –
M
bacteriochlorophyll_a + NADP+ <=> phyta-2,14-dienyl_bacteriochlorophyllide_a + NADPH + H+ not assigned
 –
M
dihydrogeranylgeranyl_bacteriopheophytin + NADP+ <=> geranylgeranyl_bacteriopheophytin + NADPH + H+ not assigned
 –
tetrahydrogeranylgeranyl_bacteriopheophytin + NADP+ <=> dihydrogeranylgeranyl_bacteriopheophytin + NADPH + H+ not assigned
 –
bacteriopheophytin_a + NADP+ <=> tetrahydrogeranylgeranyl_bacteriopheophytin + NADPH + H+ not assigned
 –
4-chloro-N-hydroxyaniline + NADP+ <=> 4-chloronitrosobenzene + NADPH + H+ not assigned
 –
M
o-Hydroxylaminobenzoate + NADPH + H+ <=> anthranilate + H2O + NADP+ not assigned
 –
M
tetrahydrobiopterin + NADP+ <=> (6R)-6-lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+ not assigned
 –
M
S-allyl-L-cysteine + O2 + NADPH + H+ <=> S-allyl-L-Cys_sulfoxide + H2O + NADP+ 1.14.13
–
M
malonyl-[acyl-carrier_protein] + isobutyryl-CoA + NADPH + H+ <=> 8-Methyl-6-nonenoate + [acyl-carrier_protein] + CoA + H2O + NADP+ 2.3.1
–
M
gamma-glutamyl-isopropylamide + O2 + NADPH + H+ <=> N-(gamma-L-glutamyl)-L-alaninol + H2O + NADP+ not assigned
 –
M
L-2-Aminopropan-1-ol + NADP+ <=> (S)-2-aminopropanal + NADPH + H+ not assigned
 –
M
(S)-2-aminopropanal + H2O + NADP+ <=> L-alanine + NADPH + H+ not assigned
 –
M
phenazine-1-carboxylic_acid + O2 + NADPH + H+ <=> 2-hydroxyphenazine-1-carboxylate + H2O + NADP+ not assigned
 –
M
trichloroacetate + O2 + NADPH <=> oxalate + Cl- + NADP+ + H+ not assigned
 –
M
Dichloroacetate + NADP+ + Cl- + H+ <=> Trichloroethylene + NADPH + O2 1.21.1
–
M
Dichloroacetate + O2 + NADPH <=> oxalate + Cl- + NADP+ + H+ not assigned
 –
M
Trichloroethylene + O2 + NADPH + H+ <=> 2,2,2-trichloroethanol + H2O + NADP+ not assigned
 –
M
O-Methylandrocymbine + NADPH <=> colcemid + NADP+ not assigned
 –
colcemid + NADPH + O2 + H+ <=> Deacetylcolchicine + NADP+ + H2O + formaldehyde 1.14.13
–
M
cinchonidine + Cinchonine + NADP+ <=> Cinchoninone + NADPH + H+ 1.1.1
–
M
Quinine + quinidine + NADP+ <=> Quinidinone + NADPH + H+ 1.1.1
–
M
2-heptaprenylphenol + O2 + NADPH + H+ <=> 3-(all-trans-heptaprenyl)benzene-1,2-diol + H2O + NADP+ 1.14.13.240 2-polyprenylphenol 6-hydroxylase
–
M
2-methoxy-6-(all-trans-heptaprenyl)phenol + O2 + NADPH + H+ <=> 2-methoxy-6-all_trans-heptaprenyl-1,4-benzoquinol + H2O + NADP+ 1.14.13.M56
–
M
2-decaprenylphenol + O2 + NADPH + H+ <=> 3-(all-trans-decaprenyl)-benzene-1,2-diol + H2O + NADP+ 1.14.13.240 2-polyprenylphenol 6-hydroxylase
–
M
3-(all-trans-decaprenyl)-1-methoxybenzene-2-ol + O2 + NADPH + H+ <=> all_trans-decaprenyl-2-methoxy-6-1,4-benzoquinol + H2O + NADP+ 1.14.13.M56
–
M
2-nonaprenylphenol + O2 + NADPH + H+ <=> 3-(all-trans-nonaprenyl)benzene-1,2-diol + H2O + NADP+ 1.14.13.240 2-polyprenylphenol 6-hydroxylase
–
M
NADP+ + H+ + e- <=> NADPH not assigned
 –
2-methoxy-6-(all-trans-nonaprenyl)phenol + O2 + NADPH + H+ <=> 2-methoxy-6-all_trans-nonaprenyl-1,4-benzoquinol + H2O + NADP+ 1.14.13.M56
–
M
4-hydroxy-3-octaprenylbenzoate + O2 + NADPH + H+ <=> 3,4-dihydroxy-5-octaprenylbenzoate + H2O + NADP+ 1.14.13.M81
–
M
4-hydroxy-3-nonaprenylbenzoate + O2 + NADPH + H+ <=> 3,4-dihydroxy-5-all-trans-nonaprenylbenzoate + H2O + NADP+ 1.14.13.M81
–
M
3-decaprenyl-4-hydroxybenzoate + O2 + NADPH + H+ <=> 5-all-trans-decaprenyl-3,4-dihydroxybenzoate + H2O + NADP+ 1.14.13.M81
–
M
3-heptaprenyl-4-hydroxybenzoate + O2 + NADPH + H+ <=> 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate + H2O + NADP+ 1.14.13.M81
–
M
stearoyl-CoA + NADPH + H+ <=> long-chain_fatty_alcohol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
dihydrocarvone + NADPH + H+ + O2 <=> 4-isopropenyl-7-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
(4R)-dihydrocarvone + NADPH + H+ + O2 <=> (3R,6R)-6-isopropenyl-3-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
d-isomenthone + NADPH + H+ + O2 <=> 7-isopropyl-4-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
versicolorin_B + NADP+ <=> Versicolorin_A + NADPH + H+ 1.3.1
–
M
(3R)-3-hydroxyhexanoyl-[acp] + NADP+ <=> 3-oxohexanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
decanoyl-[acyl-carrier_protein] + NADP+ <=> (2E)-dec-2-enoyl-[acp] + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
–
–
M
(3R)-3-hydroxydodecanoyl-[acp] + NADP+ <=> 3-oxododecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R)-3-hydroxyhexadecanoyl-[acp] + NADP+ <=> 3-oxohexadecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
(3R,6Z)-3-hydroxyoctadec-6-enoyl-[acp] + NADP+ <=> (6Z)-3-oxooctadec-6-enoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
petroselinoyl-[acp] + NADP+ <=> (2E,6Z)-octadecadienoyl-[acp] + NADPH + H+ 1.3.1
–
M
(3R)-3-hydroxy-cis-vaccenoyl-[acyl-carrier_protein] + NADP+ <=> cis-vaccenoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP+ <=> (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+ 1.3.1.105 2-methylene-furan-3-one reductase
–
M
2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP+ <=> (2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+ 1.3.1.105 2-methylene-furan-3-one reductase
–
4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NADP+ <=> (2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone + NADPH + H+ 1.3.1.105 2-methylene-furan-3-one reductase
–
3-amino-5-hydroxybenzoyl-[rifamycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> tetraketide-[rifamycin_PKS] + CoA + NADP+ + CO2 2.3.1
–
M
7-(5-amino-3,6-dioxocyclohexa-1,4-dien-1-yl)-7-hydroxy-2,6-dimethyl-3,5-dioxoheptanoyl-[rifamycin_PKS] + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> undecaketide-[rifamycin-PKS] + CoA + NADP+ + CO2 + H2O not assigned
 –
M
Proansamycin_X + NADP+ <=> 34a-Deoxy-rifamycin_W + NADPH + H+ 1.3.1
–
M
Rifamycin_B + NADP+ <=> Rifamycin_O + NADPH not assigned
 –
M
(3R)-3-hydroxyoctadecanoyl-[acp] + NADP+ <=> 3-oxooctadecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
DMSO + NADPH + H+ <=> Dimethylsulfide + H2O + NADP+ 1.8.1.M2
–
M
4-nitroso-2,6-dinitrotoluene + H2O + NADP+ <=> 2,4,6-trinitrotoluene + NADPH + H+ not assigned
 –
M
4-hydroxylamino-2,6-dinitrotoluene + NADP+ <=> 4-nitroso-2,6-dinitrotoluene + NADPH + H+ not assigned
 –
M
(2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NADP+ <=> 4-methylsulfanyl-2-oxobutanoate + NADPH + H+ 1.1.1
–
M
Dimethylsulfide + O2 + NADPH + H+ <=> DMSO + H2O + NADP+ 1.14.13.148 trimethylamine monooxygenase
–
16-hydroxypalmitic_acid + NADP+ <=> 16-oxohexadecanoic_acid + NADPH + H+ 1.1.1
–
M
16-oxohexadecanoic_acid + NADP+ + H2O <=> hexadecanedioic_acid + NADPH + H+ 1.2.1
–
M
5-chloro-3-oxoadipate + NADP+ <=> 5-chloromaleylacetate + NADPH + H+ 1.3.1.32 maleylacetate reductase
–
M
2,5-dichloro-3-oxoadipate + NADP+ <=> 2,5-dichloromaleylacetate + NADPH + H+ 1.3.1.32 maleylacetate reductase
–
M
2-chloro-4-methylphenol + O2 + NADPH + H+ <=> 3-chloro-5-methylcatechol + H2O + NADP+ 1.14.13
–
5,6-dihydrouridine_in_tRNA + NADP+ <=> uracil_in_tRNA + NADPH + H+ 1.1.1
–
(3R,5Z)-3-hydroxydodec-5-enoyl-[acp] + NADP+ <=> 3-oxo-cis-5-dodecenoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
electron-transfer_quinone + NADPH + H+ <=> electron-transfer_quinol + NADP+ 1.6.5.10 NADPH dehydrogenase (quinone)
–
Cr6+ + NADPH + O2 <=> Cr3+ + NADP+ + O2- + H+ not assigned
 –
sn-glycerol_3-phosphate + NADP+ <=> H+ + L-Glyceraldehyde_3-phosphate + NADPH 1.1.1
–
2-oxepin-2(3H)-ylideneacetyl-CoA + NADP+ + H2O <=> 3-oxo-5,6-dehydrosuberyl-CoA + NADPH + H+ not assigned
 –
Fe2+ + siderophore + NADP+ <=> siderophore-bound_Fe(III) + NADPH + H+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
curcumin + NADPH + H+ <=> dihydrocurcumin + NADP+ not assigned
 –
M
dihydrocurcumin + NADPH + H+ <=> tetrahydrocurcumin + NADP+ not assigned
 –
M
Fe2+ + N-(2,3-dihydroxybenzoyl)-L-serine_trimer + NADP+ <=> Fe(III)-enterobactin + NADPH + H+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
[a_protein_chain_elongation_factor_EF-P]-N-(beta-L-lysyl)-L-lysine34 + O2 + NADPH + H+ <=> [protein_chain_elongation_factor_EF-P]-N-(beta-lysyl)-5-hydroxy-L-lysine34 + H2O + NADP+ 1.14.13
–
1,2,4-butanetriol + NADP+ <=> (3R)-3,4-dihydroxybutanal + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Fe2+ + N-(2,3-dihydroxybenzoyl)-L-Ser + NADP+ <=> iron(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]_complex + NADPH + H+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
alpha-cembratriene-ol + O2 + NADPH + H+ <=> alpha-cembratriene-4,6-diol + H2O + NADP+ 1.14.13
–
M
beta-cembratriene-ol + O2 + NADPH + H+ <=> beta-cembratriene-4,6-diol + H2O + NADP+ 1.14.13
–
M
tomatidine + NADP+ <=> tomatid-3-one + NADPH + H+ not assigned
 –
M
9-hydroxy-3,5,7,11,13,15-hexaoxohexadecanoyl-[PKS-acp] + NADP+ <=> 3,5,7,9,11,13,15-hepta-oxo-hexadecanoyl-[PKS-acp] + NADPH + H+ 1.3.1
–
M
4-(3''-acetyl-5''-hydroxy-4''-oxo-1,4''-dihydronapthalen-2''-yl)-3-oxobutanoate + NADPH + H+ <=> (S)-4-(3''-acetyl-5''-hydroxy-4''-oxo-1,4''-dihydronapthalen-2''-yl)-3-hydroxybutanoate + NADP+ 1.1.1
–
M
chlorophyllide_a + NADP+ <=> protochlorophyllide + NADPH + H+ + light 1.3.1.33 protochlorophyllide reductase
–
cis,cis-delta13,31-3-hydroxy_C50:2-[acp] + NADP+ <=> cis,cis-delta13,31-3-oxo-C50:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis-delta19-3-hydroxyC38:1-[acp] + NADP+ <=> cis-delta19-3-oxo-C38:1-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta15,33-3-hydroxy_C52:2-[acp] + NADP+ <=> cis,cis-delta15,33-3-oxo-C52:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
(3R)-3-hydroxydocosanoyl-[acp] + NADP+ <=> 3-oxodocosanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
cis-delta11-3-hydroxyC30:1-[acp] + NADP+ <=> cis-delta11-3-oxo-C30:1-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta5,23-3-hydroxyC42:2-[acp] + NADP+ <=> cis,cis-delta5,23-3-oxo-C42:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta17,35-3-hydroxyC54:2-[acp] + NADP+ <=> cis,cis-delta17,35-3-oxo-C54:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta13,25-3-hydroxyC44:2-[acp] + NADP+ <=> cis,cis-delta13,25-3-oxo-C44:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis-delta9-3-hydroxyC28:1-[acp] + NADP+ <=> (9Z)-3-oxooctacos-9-enoyl-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta9,21-3-hydroxyC40:2-[acp] + NADP+ <=> cis,cis-delta9,21-3-oxo-C40:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis-delta13-3-hydroxyC32:1-[acp] + NADP+ <=> cis-delta13-3-oxo-C32:1-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta7,19-3-hydroxyC38:2-[acp] + NADP+ <=> cis,cis-delta7,19-3-oxo-C38:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis-delta21-3-hydroxyC40:1-[acp] + NADP+ <=> cis-delta21-3-oxo-C40:1-[acp] + NADPH + H+ 1.1.1.M9
–
M
(3R)-3-hydroxyicosanoyl-[acp] + NADP+ <=> 3-oxo-arachidoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
cis-delta15-3-hydroxyC34:1-[acp] + NADP+ <=> cis-delta15-3-oxo-C34:1-[acp] + NADPH + H+ 1.1.1.M9
–
M
(3R,7Z)-3-hydroxyhexacos-7-enoyl-[acp] + NADP+ <=> (7Z)-3-oxohexacos-7-enoyl-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta7,25-3-hydroxyC44:2-[acp] + NADP+ <=> cis,cis-delta7,25-3-oxo-C44:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta5,17-3-hydroxyC36:2[acp] + NADP+ <=> cis,cis-delta5,17-3-oxo-C36:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta19,37-3-hydroxy-C56:2-[acp] + NADP+ <=> cis,cis-delta19,37-3-oxo-C56:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
(3R)-3-hydroxydocosanoyl-[acp] + NADP+ <=> 3-oxodocosanoyl-[acp] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
M
cis,cis-delta15,27-3-hydroxyC46:2-[acp] + NADP+ <=> cis,cis-delta15,27-3-oxo-C46:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
(3R)-3-hydroxytetracosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxotetracosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.86 fatty-acyl-CoA synthase system
–
M
cis,cis-delta9,27-3-hydroxyC46:2-[acp] + NADP+ <=> cis,cis-delta9,27-3-oxo-C46:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta21,39-3-hydroxyC58:2-[acp] + NADP+ <=> cis,cis-delta21,39-3-oxo-C58:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta11,23-3-hydroxyC42:2-[acp] + NADP+ <=> cis,cis-delta11,23-3-oxo-C42:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta17,29-3-hydroxyC48:2-[acp] + NADP+ <=> cis,cis-delta17,29-3-oxo-C48:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
(3R,5Z)-3-hydroxytetracos-5-enoyl-[acp] + NADP+ <=> (5Z)-3-oxotetracos-5-enoyl-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta11,29-3-hydroxy_C48:2-[acp] + NADP+ <=> cis,cis-delta11,29-3-oxo-C48:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis-delta17-3-hydroxyC36:1-[acp] + NADP+ <=> cis-delta17-3-oxo-C36:1-[acp] + NADPH + H+ 1.1.1.M9
–
M
cis,cis-delta19,31-3-hydroxyC50:2-[acp] + NADP+ <=> cis,cis-delta19,31-3-oxo-C50:2-[acp] + NADPH + H+ 1.1.1.M9
–
M
O2 + roxarsone_(III) + NADPH <=> H2O + roxarsone + NADP+ 1.20.1.M1
–
[(3S,4R)-4-(octanoyl)-5-oxooxolan-3-yl]methyl_phosphate + NADP+ <=> (4-octanoyl-5-oxo-2H-furan-3-yl)methyl_phosphate + NADPH + H+ 1.3.1.113 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase
–
[(3S,4R)-4-(6-methyloctanoyl)-5-oxooxolan-3-yl]methyl_phosphate + NADP+ <=> [4-(6-methyloctanoyl)-5-oxo-2H-furan-3-yl]methyl_phosphate + NADPH + H+ 1.3.1.113 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase
–
1-(long-chain_acyl)-sn-glycerol_3-phosphate + NADP+ <=> 1-long-chain_acyl-glycerone_3-phosphate + NADPH + H+ 1.1.1.101 acylglycerone-phosphate reductase
–
2-Hexaprenyl-6-methoxyphenol + O2 + NADPH + H+ <=> 2-methoxy-6-(all-trans-hexaprenyl)-1,4-benzoquinol + H2O + NADP+ 1.14.13
–
M
stearoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-octadec-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.86 fatty-acyl-CoA synthase system
–
M
4alpha-methyl-5alpha-cholesta-8-en-3-ol + NADP+ <=> 4alpha-methyl-5alpha-cholesta-8-en-3-one + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
M
5alpha-cholesta-8-en-3beta-ol + NADP+ <=> H+ + 5alpha-cholesta-8-en-3-one + NADPH 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
M
(3R)-3-hydroxybutanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> acetoacetyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
butanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-but-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
(3R)-3-hydroxyhexanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxohexanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
hexanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-hex-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
(3R)-3-hydroxyoctanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxooctanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
octanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-oct-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
(3R)-3-hydroxydecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxodecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
decanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-dec-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
(3R)-3-hydroxydodecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxododecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
dodecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-dodec-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
(3R)-3-hydroxytetradecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxotetradecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
myristoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-tetradec-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
(3R)-3-hydroxyhexadecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxohexadecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
palmitoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-hexadec-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
M
(3R)-3-hydroxyacyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxoacyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
acyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> trans-2,3-dehydroacyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
very-long-chain_fatty_alcohol + NADP+ + CoA <=> behenoyl-CoA + NADPH + H+ 1.2.1
–
M
H+ + (E)-5-(methylsulfanyl)pentanal_oxime + NADPH + O2 + L-cysteine <=> (E)-1-(L-cystein-S-yl)-N-hydroxy-omega-(methylsulfanyl)pentan-1-imine + NADP+ + H2O not assigned
 –
H+ + 6-Methylthiohexanaldoxime + NADPH + O2 + L-cysteine <=> (E)-1-(L-cystein-S-yl)-N-hydroxy-omega-(methylsulfanyl)hexan-1-imine + NADP+ + H2O not assigned
 –
H+ + 4-methylthioheptanaldoxime + NADPH + O2 + L-cysteine <=> (E)-1-(L-cystein-S-yl)-N-hydroxy-omega-(methylsulfanyl)heptan-1-imine + NADP+ + H2O not assigned
 –
H+ + 4-methylthiooctanaldoxime + NADPH + O2 + L-cysteine <=> (E)-1-(L-cystein-S-yl)-N-hydroxy-omega-(methylsulfanyl)octan-1-imine + NADP+ + H2O not assigned
 –
H+ + 4-methylthiononanaldoxime + NADPH + O2 + L-cysteine <=> (E)-1-(L-cystein-S-yl)-N-hydroxy-omega-(methylsulfanyl)nonan-1-imine + NADP+ + H2O not assigned
 –
5-methylthiopentylglucosinolate + O2 + NADPH + H+ <=> 5-(methylsulfinyl)pentyl-glucosinolate + H2O + NADP+ 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
M
6-methylthiohexylglucosinolate + O2 + NADPH + H+ <=> 6-methylsulfinylhexyl-glucosinolate + H2O + NADP+ 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
M
7-methylthioheptyl_glucosinolate + O2 + NADPH + H+ <=> 7-(methylsulfinyl)heptyl-glucosinolate + H2O + NADP+ 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
M
8-methylthiooctyl_glucosinolate + O2 + NADPH + H+ <=> 8-(methylsulfinyl)octyl-glucosinolate + H2O + NADP+ 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
M
keto-L-sorbose + NADP+ <=> 5-dehydro-D-fructose + NADPH + H+ 1.1.1.123 sorbose 5-dehydrogenase (NADP+)
–
2,3,4-saturated_fatty_acyl_CoA + NADP+ <=> trans-2-enoyl-CoA + NADPH + H+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
–
NAD+ + 2 NADPH + 2 oxidized_ferredoxin_iron-sulfur_cluster <=> NADH + H+ + 2 NADP+ + reduced_ferredoxin_iron-sulfur_cluster 1.6.1.4 NAD(P)+ transhydrogenase (ferredoxin)
–
NADH + H+ + 2 NADP+ + 2 reduced_ferredoxin_iron-sulfur_cluster <=> NAD+ + 2 NADPH + 2 reduced_ferredoxin_iron-sulfur_cluster 1.6.1.4 NAD(P)+ transhydrogenase (ferredoxin)
–
Orange_II + 2 NADPH + 2 H+ <=> Sulfanilic_acid + 1-amino-2-hydroxynaphthalene + 2 NADP+ + 2 NAD+ 1.7.1.17 FMN-dependent NADH-azoreductase
–
mevaldyl-CoA + NADPH + H+ + H2O <=> (R)-mevalonate + CoA + NADP+ 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
–
(R)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ <=> (R)-mevalonate + CoA + 2 NADP+ 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
–
erucoyl-CoA + NADPH + H+ <=> (13Z)-docos-13-enal + CoA + NADP+ 1.2.1.50 long-chain acyl-protein thioester reductase
–
Arachidonoyl-CoA + NADPH + H+ <=> (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenal + CoA + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
1.2.1.50 long-chain acyl-protein thioester reductase
–
–
ricinoleoyl-CoA + NADPH + H+ <=> (9Z,12R)-12-hydroxyoctadec-9-enal + CoA + NADP+ 1.2.1.50 long-chain acyl-protein thioester reductase
–
2-methyl-1-hexadecanoyl-CoA + NADPH + H+ <=> 2-methyl-1-hexadecanal + CoA + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
heptadecanoyl-CoA + NADPH + H+ <=> heptadecanal + CoA + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
hexacosanoyl-CoA + NADPH + H+ <=> hexacosanal + CoA + NADP+ 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
–
arachidoyl-CoA + NADPH + H+ <=> eicosanal + CoA + NADP+ 1.2.1.50 long-chain acyl-protein thioester reductase
1.2.1.B25
–
–
lauroyl-CoA + NADPH + H+ <=> dodecanal + CoA + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
1.2.1.50 long-chain acyl-protein thioester reductase
1.2.1.B25
–
–
–
6 methylmalonyl-CoA + propionyl-CoA + 6 NADPH + 6 H+ <=> 6-Deoxyerythronolide_b + 7 CoA + 6 CO2 + H2O + 6 NADP+ 2.3.1.94 6-deoxyerythronolide-B synthase
–
8 malonyl-CoA + 4 NADPH + 16 H+ <=> 8 CoA + (2E,4E,10E)-15-hydroxyhexadeca-2,4,10-trienoic_acid + 8 CO2 + 4 NADP+ + 6 H2O 2.3.1.B39
–
9 malonyl-CoA + 5 NADPH + 19 H+ <=> 9 CoA + (4E,6Z,12E)-17-hydroxyoctadeca-4,6,12-trienoic_acid + 9 CO2 + 5 NADP+ + 7 H2O 2.3.1.B39
–
8 malonyl-CoA + NADPH + H+ <=> 8 CoA + (4E,6E,8E,10E,12E,14E)-3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoic_acid + 8 CO2 + NADP+ + H2O 2.3.1.B40
–
propionyl-CoA + 5 (S)-methylmalonyl-CoA + (2S)-ethylmalonyl-CoA + 6 NADPH + 6 H+ <=> 8-ethyl-8-desmethyl-6-deoxyerythronolide_B + 7 CoA + 6 CO2 + H2O + 6 NADP+ 2.3.1.94 6-deoxyerythronolide-B synthase
–
malonyl-CoA + 4-coumaroyl-CoA + NADPH <=> 5''-deoxyflavanone + CoA + CO2 + NADP+ 2.3.1.74 chalcone synthase
–
propionyl-CoA + malonyl-CoA + NADPH <=> 6-Ethylsalicylic_acid + CoA + CO2 + NADP+ 2.3.1.165 6-methylsalicylic-acid synthase
–
acetyl-CoA + 8 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine + 11 H+ <=> dihydromonacolin_L + 9 CoA + 8 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O 2.3.1.161 lovastatin nonaketide synthase
–
acetyl-CoA + malonyl-CoA + [2-methylbutanoate_polyketide_synthase] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine <=> (S)-2-methylbutanoyl-[2-methylbutanoate_polyketide_synthase] + 2 CoA + CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O 2.3.1.244 2-methylbutanoate polyketide synthase
–
2 malonyl-CoA + [2-methylbutanoate_polyketide_synthase] + 2 NADPH + 3 H+ + S-adenosyl-L-methionine <=> (S)-2-methylbutanoyl-[2-methylbutanoate_polyketide_synthase] + 2 CoA + 2 CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O 2.3.1.244 2-methylbutanoate polyketide synthase
–
9 malonyl-CoA + 11 NADPH + 10 H+ + S-adenosyl-L-methionine + holo-[lovastatin_nonaketide_synthase] <=> dihydromonacolin_L-[lovastatin_nonaketide_synthase] + 9 CoA + 9 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O 2.3.1.161 lovastatin nonaketide synthase
–
acetyl-CoA + malonyl-CoA + NADPH + H+ + S-adenosyl-L-methionine <=> 4-hydroxy-6-[(1E,3E,5E)-1-methylhepta-1,3,5-trien-1-yl]-2H-pyran-2-one + 4-hydroxy-6-[(1E,3E,5E,7E)-3-methylnona-1,3,5,7-tetraen-1-yl]-2H-pyran-2-one + CoA + CO2 + NADP+ + S-adenosyl-L-homocysteine + H2O 2.3.1.161 lovastatin nonaketide synthase
–
acetoacetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ <=> palmitate + (n+1)_CoA + n CO2 + 2n NADP+ 2.3.1.85 fatty-acid synthase system
–
arachidoyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + 8 H+ <=> tetramethyl-branched_mycocerosoyl-CoA + 4 CoA + 4 CO2 + 8 NADP+ + 4 H2O 2.3.1.111 mycocerosate synthase
–
a_long-chain_acyl-[mycocerosic_acid_synthase] + 4 methylmalonyl-CoA + 8 NADPH + 8 H+ <=> a_tetramethylated-mycocerosoyl-[mycocerosate_synthase] + 4 CoA + 4 CO2 + 8 NADP+ + 4 H2O 2.3.1.111 mycocerosate synthase
–
a_long-chain_acyl-[mycocerosic_acid_synthase] + 3 methylmalonyl-CoA + 6 NADPH + 6 H+ <=> a_trimethylated-mycocerosoyl-[mycocerosate_synthase] + 3 CoA + 3 CO2 + 6 NADP+ + 3 H2O 2.3.1.111 mycocerosate synthase
–
palmitoyl-CoA + 3 (S)-methylmalonyl-CoA + 6 NADPH + 6 H+ + holo-[mycolipanoate_synthase] <=> mycolipanoyl-[mycolipanoate_synthase] + 4 CoA + 3 CO2 + 6 NADP+ + 3 H2O 2.3.1.252 mycolipanoate synthase
–
palmitoyl-CoA + 3 (R)-2-methylmalonyl-CoA + 6 NADPH + 6 H+ + holo-[mycolipanoate_synthase] <=> mycolipanoyl-[mycolipanoate_synthase] + 4 CoA + 3 CO2 + 6 NADP+ + 3 H2O 2.3.1.252 mycolipanoate synthase
–
4-hydroxybenzoyl-[4-hydroxyphenylalkanoate_synthase] + 9 malonyl-CoA + 18 NADPH + 18 H+ + holo-[4-hydroxyphenylalkanoate_synthase] <=> 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate_synthase] + 9 CO2 + 9 CoA + 18 NADP+ + 9 H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
4-hydroxybenzoyl-[4-hydroxyphenylalkanoate_synthase] + 9 malonyl-CoA + 18 NADPH + 18 H+ + holo-[4-hydroxyphenylalkanoate_synthase] <=> 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate_synthase] + 9 CO2 + 9 CoA + 18 NADP+ + 9 H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
hexanoyl-CoA + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 22 NADPH + 22 H+ <=> a_mycoketide-CoA + 10 CO2 + 10 CoA + 22 NADP+ + 11 H2O 2.3.1.295 mycoketide-CoA synthase
–
3 malonyl-CoA + 2 (S)-methylmalonyl-CoA + icosanoyl-[(phenol)carboxyphthiodiolenone_synthase] + 5 NADPH <=> C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + 5 CoA + 5 NADP+ + 5 CO2 + 2 H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
3 malonyl-CoA + 2 (S)-methylmalonyl-CoA + docosanoyl-[(phenol)carboxyphthiodiolenone_synthase] + 5 NADPH <=> C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + 5 CoA + 5 NADP+ + 5 CO2 + 2 H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
eicosenoyl-CoA + 2 NADPH + 2 H+ <=> eicosanol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ <=> Mevalonolactone + CoA + 2 NADP+ + H2O 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
–
acetoacetyl-CoA + 3 malonyl-CoA + NADPH + H+ <=> Triacetate_lactone + CoA + NADP+ 2.3.1.165 6-methylsalicylic-acid synthase
–
oleoyl-CoA + NADPH <=> cis-9-octadecenal + NADP+ + CoA 1.2.1.42 hexadecanal dehydrogenase (acylating)
1.2.1.50 long-chain acyl-protein thioester reductase
1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
–
–
stearoyl-CoA + NADPH <=> octadecanal + NADP+ + CoA 1.2.1.42 hexadecanal dehydrogenase (acylating)
1.2.1.50 long-chain acyl-protein thioester reductase
1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
1.2.1.84 alcohol-forming fatty acyl-CoA reductase
1.2.1.B25
–
–
–
–
–
decanoyl-CoA + 2 NADPH + 2 H+ <=> Decanol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
myristoyl-CoA + NADPH <=> Tetradecanal + CoA + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
1.2.1.50 long-chain acyl-protein thioester reductase
–
–
lauroyl-CoA + 2 NADPH + 2 H+ <=> Dodecanol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
5-hydroxyferuloyl-CoA + NADPH <=> 5-Hydroxyferulic_aldehyde + CoA + NADP+ 1.2.1.44 cinnamoyl-CoA reductase
–
2-oxobutyrate + CoA + NADP+ <=> propionyl-CoA + CO2 + NADPH 1.2.1.51 pyruvate dehydrogenase (NADP+)
–
palmitoleoyl-CoA + NADPH + H+ <=> cis-9-hexadecenal + CoA + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
1.2.1.50 long-chain acyl-protein thioester reductase
–
–
Hydroxypyruvate + CoA + NADP+ <=> hydoxyacetyl-CoA + CO2 + NADPH 1.2.1.51 pyruvate dehydrogenase (NADP+)
–
linoleoyl-CoA + NADPH <=> cis-9,12-octadecadienal + NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
pentanal + CoA + NADP+ <=> pentanoyl-CoA + NADPH + H+ 1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)
–
(S)-3-hydroxy-3-methylglutaryl-CoA + NADPH <=> mevaldehyde + CoA + NADP+ 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
–
octanoyl-CoA + NADPH + H+ <=> octanal + CoA + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
oleoyl-CoA + 2 NADPH + 2 H+ <=> octadecenol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
tetraeicos-cis-15-enoyl-CoA + NADPH <=> tetraeicos-cis-15-en-1-ol + CoA + NADP+ 1.2.1.50 long-chain acyl-protein thioester reductase
–
erucyl-CoA + 2 NADPH + 2 H+ <=> erucyl_alcohol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
oleoyl-CoA + NADPH <=> (9Z)-octadecenal + CoA + NADP+ 1.2.1.B25
–
ricinoleoyl-CoA + 2 NADPH + 2 H+ <=> (9Z,12R)-octadec-9-ene-1,12-diol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
2-methylpalmitoyl-CoA + 2 NADPH + 2 H+ <=> 2-methylhexadecanol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
2-methylstearoyl-CoA + 2 NADPH + 2 H+ <=> 2-methyloctadecanol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
arachidoyl-CoA + 2 NADPH + 2 H+ <=> arachidol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
hexacosanoyl-CoA + 2 NADPH + 2 H+ <=> hexacosanoyl_alcohol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
lignoceroyl-CoA + 2 NADPH + 2 H+ <=> tetracosanoyl_alcohol + 2 NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
cis-11-hexadecenal + CoA + NADP+ <=> DELTA11-acyl-CoA + NADPH + H+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
Arachidonoyl-CoA + NADPH <=> cis-5,8,11,14-eicosatetraenal + NADP+ + CoA 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
(R)-3-hydroxy-3-methylglutaryl-CoA + NADPH <=> mevalonate + CoA + NADP+ 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
–
1-octen-3-one + NADPH + H+ <=> octan-3-one + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
–
isatin + NADPH + H+ <=> 3-hydroxyindolin-2-one + NADP+ 1.1.1.21 aldose reductase
–
lithocholic_acid + NADP+ <=> Dehydrolithocholic_acid + NADPH 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
benzyl_methyl_sulfide + NADPH + H+ + O2 <=> [(methylsulfinyl)methyl]benzene + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
glutathionyl-4-hydroxynonenal + NADPH + H+ <=> glutathione-1,4-dihydroxynonane + NADP+ 1.1.1.21 aldose reductase
–
S-(4-hydroxy-1-oxononan-3-yl)glutathione + NADPH + H+ <=> glutathione-1,4-dihydroxynonane + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
ethyl_pyruvate + NADPH + H+ <=> ethyl_L-lactate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
5-dimethylaminopropylamino-8-hydroxytriazoloacridinone + NADPH + H+ + O2 <=> 5-[[3-(dimethylnitroryl)propyl]amino]-8-hydroxy-6H-[1,2,3]triazolo[4,5,1-de]acridin-6-one + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
5alpha-acetoxy-10beta-hydroxytaxadiene + O2 + NADPH + H+ <=> 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl_acetate + NADP+ + H2O 1.14.13.146 taxoid 14beta-hydroxylase
–
hydroperoxy_fatty_acid + NADPH + H+ <=> a_hydroxy_fatty_acid + NADP+ + H2O 1.11.1.22 hydroperoxy fatty acid reductase
–
4,4''-diapolycopen-4-al + NADP+ <=> 4,4''-diapolycopenoic_acid + NADPH + H+ 1.2.1.B23
–
ethyl-(2R)-allylacetoacetate + NADPH + H+ <=> ethyl_(2R)-2-[(1S)-1-hydroxyethyl]pent-4-enoate + NADP+ 1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
(R)-mevaldehyde + NADPH + H+ <=> (R)-mevalonate + NADP+ 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
–
mevaldehyde + NADPH <=> (R)-mevalonate + NADP+ 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
–
Ethionamide + NADPH + O2 + H+ <=> 2-ethyl-N-hydroxypyridine-4-carbothioamide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
thiacetazone + 2 NADPH + 2 O2 <=> (E)-{(2E)-[4-(acetylamino)benzylidene]hydrazinylidene}(amino)methanesulfinic_acid + 2 NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
L-tyrosine + 2 NADP+ + 2 Cl- <=> 3,5-dichloro-L-tyrosine + 2 NADPH + 2 H+ 1.21.1.1 iodotyrosine deiodinase
–
3-chloro-L-tyrosine + NADPH + H+ <=> L-tyrosine + NADP+ + Cl- 1.21.1.1 iodotyrosine deiodinase
–
L-tyrosine + 2 NADP+ + 2 Br- <=> 3,5-Dibromo-L-tyrosine + 2 NADPH + 2 H+ 1.21.1.1 iodotyrosine deiodinase
–
3-bromo-L-Tyr + NADPH + H+ <=> L-tyrosine + NADP+ + Br- 1.21.1.1 iodotyrosine deiodinase
–
(2S)-2-(prop-2-en-1-yl)cyclohexanone + NADPH + H+ + O2 <=> (7R)-7-(prop-2-en-1-yl)oxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
(2R)-2-ethylcyclohexanone + NADPH + H+ + O2 <=> (7S)-7-ethyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
1-(3-methyl-1,4-dioxidoquinoxalin-2-yl)ethanone + NADPH + H+ <=> 1-(3-methyl-1,4-dioxidoquinoxalin-2-yl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
1-(3-methyl-4-oxidoquinoxalin-2-yl)ethanone + NADPH + H+ <=> 1-(3-methyl-4-oxidoquinoxalin-2-yl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-amino-5-cyanopyrrolo[2,3-d]pyrimidine + 2 NADPH + 2 H+ <=> 2-amino-5-amino-methyl-pyrrolo[2,3-d]pyrimidine + 2 NADP+ 1.7.1.13 preQ1 synthase
–
3,5-dimethylcyclohexanone + NADPH + H+ + O2 <=> 4,6-dimethyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
3-(1,3-benzodioxol-5-yl)cyclobutanone + NADPH + H+ + O2 <=> 4-(1,3-benzodioxol-5-yl)dihydrofuran-2(3H)-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
3-(3,4,5-trimethoxyphenyl)cyclobutanone + NADPH + H+ + O2 <=> 4-(3,4,5-trimethoxyphenyl)dihydrofuran-2(3H)-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
4,4-dimethylcyclohexanone + NADPH + H+ + O2 <=> 5,5-dimethyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
5-cyanopyrrolo[2,3-d]pyrimidin-4-one + 2 NADPH + 2 H+ <=> 5-amino-methyl-pyrrolo[2,3-d]pyrimidin-4-one + 2 NADP+ 1.7.1.13 preQ1 synthase
–
ethyl_4-oxocyclohexanecarboxylate + NADPH + H+ + O2 <=> ethyl_7-oxooxepane-4-carboxylate + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
pent-1-en-3-ol + NADP+ <=> 1-penten-3-one + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
cortisone + NADPH + H+ <=> 20beta-hydroxycortisone + NADP+ 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
12-ketochenodeoxycholic_acid + NADP+ <=> cholic_acid + NADPH + H+ 1.1.1.176 12alpha-hydroxysteroid dehydrogenase
–
daidzein + NADPH + H+ + O2 <=> 2''-hydroxydaidzein + NADP+ + H2O 1.14.13.53 4'-methoxyisoflavone 2'-hydroxylase
1.14.13.89 isoflavone 2'-hydroxylase
–
–
2,2''-dihydroxybiphenyl + NADPH + O2 <=> 2,2'',3-trihydroxybiphenyl + NADP+ + H2O 1.14.13.44 2-hydroxybiphenyl 3-monooxygenase
–
dibenzofuran + NADPH + H+ + O2 <=> 2,2'',3-trihydroxybiphenyl + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
L-phenylalanine + NADPH + O2 <=> L-tyrosine + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
4-hydroxyphenylpyruvate + NADPH + NH3 <=> L-tyrosine + NADP+ + H2O 1.4.1.2 glutamate dehydrogenase
–
2-methylacetoacetyl-CoA + NADPH <=> 2-methyl-3-hydroxybutyryl-CoA + NADP+ 1.1.1.36 acetoacetyl-CoA reductase
–
hexadecane + NADPH + H+ + O2 <=> hexadecanol + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
5-hydroxylysine + NADP+ <=> alpha-amino-delta-hydroxyadipate-semialdehyde + NADPH 1.4.1.15 lysine dehydrogenase
–
NTP + NADP+ <=> 2''-deoxyribonucleoside_triphosphate + NADPH + H2O 1.17.4.2 ribonucleoside-triphosphate reductase (thioredoxin)
–
5beta-pregnane-17alpha,20beta,21-triol-3,11-dione + NADPH <=> 5beta-pregnane-3alpha,17alpha,20beta,21-tetraol-11-one + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
D-xylosone + NADP+ <=> D-Lyxose + NADPH 1.1.1.263 1,5-anhydro-D-fructose reductase
–
(-)-Carvone + NADPH <=> dihydrocarvone + NADP+ 1.3.1.31 2-enoate reductase
–
NADPH + K4Fe(CN)6 <=> NADP+ + K3Fe(CN)6 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
–
Dehydrolithocholic_acid + NADPH <=> isolithocholic_acid + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
L-1-Aminopropan-2-ol + NADP+ <=> aminoacetone + NADPH 1.1.1.75 (R)-aminopropanol dehydrogenase
–
1-nitrocyclohexene + NADPH + H+ <=> Nitrocyclohexane + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
–
ethylene_glycol + NADP+ <=> Glyoxal + NADPH 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.79 glyoxylate reductase (NADP+)
–
–
heptenal + NADPH <=> Heptanal + NADP+ 1.3.1.27 2-hexadecenal reductase
–
cis-2-heptenal + NADPH <=> Heptanal + NADP+ 1.3.1.27 2-hexadecenal reductase
–
thiazolidine-4-carboxylic_acid + NADP+ <=> 1-pyrroline-3-thio-5-carboxylate + NADPH 1.5.1.2 pyrroline-5-carboxylate reductase
–
(E)-4-hydroxy-3-methylbut-2-en-1-yl_diphosphate + NADPH <=> dimethylallyl_diphosphate + isopentenyl_diphosphate + NADP+ + H2O 1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase
–
B
L-selenocysteine + NADPH <=> L-selenocystine + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
4-oxonon-2-enal + NADPH <=> 4-oxononanal + 4-hydroxy-2-nonenal + 1-hydroxynon-2-en-4-one + 1,4-dihydroxynon-2-ene + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 <=> ent-sandaracopimaradien-3beta-ol + NADP+ + H2O 1.14.14.70 ent-sandaracopimaradiene 3-hydroxylase
–
isopentenyl_diphosphate + NADP+ + H2O <=> (E)-4-hydroxy-3-methylbut-2-en-1-yl_diphosphate + NADPH 1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase
–
dihydroquercetin + NADPH <=> catechin + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
–
2,3-trans-3,4-cis-leucoanthocyanidin + NADPH <=> catechin + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
–
taxifolin + NADPH <=> catechin + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
–
(20S)-dammarenediol + NADPH + H+ + O2 <=> protopanaxadiol + NADP+ + H2O 1.14.13.183 dammarenediol 12-hydroxylase
–
5''-O-methyl-7,8-didemethyl-8-hydroxyflavin + NADPH + H+ <=> 8-hydroxypyrimido[4,5-b]-2,4-(3H,10H)-dione + NADP+ 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
–
5-deaza-8-hydroxyisoalloxazine + NADPH + H+ <=> 8-hydroxypyrimido[4,5-b]-2,4-(3H,10H)-dione + NADP+ 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
–
eicosapentaenoic_acid + NADPH + H+ + O2 <=> 20-hydroxyeicosapentaenoic_acid + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
1.14.14.79 docosahexaenoic acid omega-hydroxylase
–
–
bilirubin-IXa + NADP+ <=> biliverdin_IXa + NADPH + H+ 1.3.1.24 biliverdin reductase
–
dihydrofluorouracil + NADP+ <=> 5-fluorouracil + NADPH + H+ 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
(+)-limonene + NADPH + O2 <=> (2S,4S)-carveol + NADP+ + H2O 1.14.14.51 (S)-limonene 6-monooxygenase
–
(2S,4S)-carveol + NADP+ <=> (S)-carvone + NADPH 1.1.1.54 allyl-alcohol dehydrogenase
1.3.1.102 2-alkenal reductase (NADP+)
–
–
traumatin + NADPH + H+ <=> 12-oxododecanoic_acid + NADP+ 1.3.1.27 2-hexadecenal reductase
–
10-[(N,N-dimethylaminooctyl)-2-(trifluoromethyl)]phenothiazine + NADPH + H+ + O2 <=> 10-[(N,N-dimethylaminooctyl)-2-(trifluoromethyl)]phenothiazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
methyl_(2-thienyl)_sulfide + NADPH + H+ + O2 <=> 2-(methylsulfanyl)thiophene_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2-cyanobenzaldehyde + NADP+ + H2O <=> 2-cyanobenzoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
–
2-[(methylsulfanyl)methyl]furan + NADPH + H+ + O2 <=> 2-[(methylsulfanyl)methyl]furan_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
docosahexaenoic_acid + NADPH + H+ + O2 <=> 22-hydroxydocosahexaenoic_acid + NADP+ + H2O 1.14.14.79 docosahexaenoic acid omega-hydroxylase
–
3-bromobenzaldehyde + NADP+ + H2O <=> 3-Bromobenzoic_acid + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
7,8-didemethyl-8-hydroxy-5-deazariboflavin_5''-phosphate + NADPH + H+ <=> 1-deoxy-1-(8-hydroxy-2,4-dioxo-1,3,4,5-tetrahydropyrimido[4,5-b]quinolin-10(2H)-yl)-5-O-phospho-D-ribitol + NADP+ 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
–
prostamide_D2 + NADPH + H+ <=> 9alpha,11beta-prostamide_F2 + NADP+ 1.1.1.188 prostaglandin-F synthase
–
5alpha-dihydrocortisol + NADPH <=> 3alpha,5alpha-tetrahydrocortisol + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
valencene + NADPH + H+ + O2 <=> alpha-nootkatol + beta-nootkatol + NADP+ + H2O 1.14.13.121 premnaspirodiene oxygenase
–
benzyl_ethyl_sulfide + NADPH + H+ + O2 <=> benzyl_ethyl_sulfide_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
butyl_ethyl_sulfide + NADPH + H+ + O2 <=> butyl_ethyl_sulfide_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
n-butyl_methyl_sulfide + NADPH + H+ + O2 <=> butyl_methyl_sulfide_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
4-ethylcyclohexanone + NADPH <=> 4-ethylcyclohexanol + NADP+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
–
–
4-hydroxy-2-nonenal + NADPH <=> 4-hydroxynonanal + NADP+ 1.3.1.27 2-hexadecenal reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
–
–
–
–
1alpha,25-dihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,23,25-trihydroxyvitamin_D3 + 25,26,27-trinor-23-ene-1alpha-hydroxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
1alpha,25-dihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,23S,25,26-tetrahydroxyvitamin_D3 + 1alpha,23S,25-trihydroxyvitamin_D3 + 25,26,27-trinor-23-ene-1alpha-hydroxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 25,26,27-trinor-23-ene-vitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
1,2-dideoxy-D-threo-3-hexulose_6-phosphate + NADPH + H+ <=> 2-C-ethyl-D-erythritol_4-phosphate + NADP+ 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase
–
4-hydroxyacetophenone + NADPH + O2 <=> 4-hydroxyphenyl_acetate + NADP+ + O2 1.14.13.92 phenylacetone monooxygenase
–
glyceollin_II + NADPH + H+ + H2O <=> (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + NADP+ + O2 1.14.14.135 glyceollin synthase
–
(+)-marmesin + NADP+ + H+ + O2 <=> psoralen + flavin + acetone + H2O 1.14.14.141 psoralen synthase
–
acetaminophen + NADPH + H+ <=> N-acetyl-p-benzoquinoneimine + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
coenzyme_F0 + NADPH + H+ <=> reduced_coenzyme_F0 + NADP+ 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
–
sulfoquinovose + NADP+ <=> 6-deoxy-6-sulfo-D-glucono-1,5-lactone + NADH + H+ 1.1.1.390 sulfoquinovose 1-dehydrogenase
–
2-oxobutyrate + NADPH + NH3 <=> L-2-aminobutanoate + NADP+ + H2O 1.4.1.4 glutamate dehydrogenase (NADP+)
–
NADPH + 2-acetolactate <=> NADP+ + 3-hydroxy-3-methyl-2-oxobutanoic_acid 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
NADP+ + 3-hydroxy-3-methyl-2-oxobutanoic_acid <=> NADPH + acetolactate 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
L-ribose + NADPH <=> ribitol + NADP+ 1.1.1.21 aldose reductase
–
2-dehydro-D-glucose + NADPH + H+ <=> D-fructose + NADP+ 1.1.1.307 D-xylose reductase
–
2 cob(II)alamin-[cyanocobalamin_reductase] + 2 cyanide + NADP+ <=> 2 vitamin_B12 + 2 [cyanocobalamin_reductase] + NADPH + H+ 1.16.1.6 cyanocobalamin reductase (cyanide-eliminating)
–
D-arabitol_5-phosphate + NADP+ <=> D-ribulose_5-phosphate + NADPH + H+ 1.1.1.301 D-arabitol-phosphate dehydrogenase
–
reduced_flavodoxin + NADP+ <=> oxidized_flavodoxin_I + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
2,4-difluorobenzaldehyde + NADPH + H+ <=> (2,4-difluorophenyl)methanol + NADP+ 1.1.1.72 glycerol dehydrogenase (NADP+)
–
(2R)-2,4-dihydroxybutanal + NADPH + H+ <=> (2R)-2,4-dihydroxybutanol + NADP+ 1.1.1.72 glycerol dehydrogenase (NADP+)
–
(2S)-2,4-dihydroxybutanal + NADPH + H+ <=> (2S)-2,4-dihydroxybutanol + NADP+ 1.1.1.72 glycerol dehydrogenase (NADP+)
–
D-ornithine + pyruvate + NADPH + H+ <=> N5-(L-1-carboxyethyl)-D-ornithine + NADP+ + H2O 1.5.1.24 N5-(carboxyethyl)ornithine synthase
–
5alpha-dihydrotestosterone + NADPH + H+ <=> 5alpha-Androstane-3beta,17beta-diol + 5alpha-androstane-3,17-dione + NADP+ 1.1.1.62 17beta-estradiol 17-dehydrogenase
–
(3R,4S/3S,4R)-3,4-(cis)acetate-beta-lactam + NADPH + H+ <=> 4-hydroxyazetidine-2,3-diyl_diacetate + NADP+ 1.1.1.21 aldose reductase
–
4-acetylbenzonitrile + NADPH + H+ <=> 1-(4-cyanophenyl)ethanol + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
5alpha-dihydrotestosterone + NADPH <=> 5alpha-androstane-3,17-dione + NADP+ 1.1.1.62 17beta-estradiol 17-dehydrogenase
–
1alpha,25-dihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,23,25-trihydroxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
1alpha-hydroxyvitamin_D2 + NADPH + H+ + O2 <=> 1alpha,24-dihydroxyvitamin_D2 + 1alpha,25-dihydroxyvitamin_D2 + 26-carboxy-1alpha,24-dihydroxyvitamin_D2 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
1alpha,23,25-trihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,25-dihydroxyvitamin_D3-26,23-lactone + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
1alpha,25-dihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,25-dihydroxyvitamin_D3-26,23-lactone + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,25-dihydroxyvitamin_D3-26,23-lactone + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
1alpha,25-dihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,24(R)-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 24,25,26,27-tetranor-23-hydroxyvitamin-D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
2 Fe(III)-ferrozine + NADPH <=> 2 Fe(II)-ferrozine + NADP+ + H+ 1.16.1.10 ferric-chelate reductase [NAD(P)H]
–
Heptanal + O2 + 2 NADPH + 2 H+ <=> pentane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
hexanal + O2 + 2 NADPH + 2 H+ <=> pentane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
Undecanal + O2 + 2 NADPH + 2 H+ <=> decane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
2-trans-octadecenal + O2 + 2 NADPH + 2 H+ <=> 1-heptadecene + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
hexadecanal + O2 + 2 NADPH + 2 H+ <=> alkane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
octadecanal + O2 + NADPH <=> alkane + formate + H2O + NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
Heptanal + O2 + 2 NADPH + 2 H+ <=> hexane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
lanosterol + O2 + NADPH + H+ <=> 4,4-dimethylcholesta-8,14,24-trienol + formate + NADP+ + H2O 1.14.14.154 sterol 14alpha-demethylase
–
Isobutyraldehyde + O2 + 2 NADPH + 2 H+ <=> propane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
Butyraldehyde + O2 + 2 NADPH + 2 H+ <=> propane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
hexadecanal + O2 + 2 NADPH + 2 H+ <=> pentadecane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
octanal + O2 + 2 NADPH + 2 H+ <=> heptane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
hexadecanal + O2 + 2 NADPH + 2 H+ <=> an_alkane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
Nonanal + O2 + 2 NADPH + 2 H+ <=> Octane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
decanal + O2 + 2 NADPH + 2 H+ <=> n-nonane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
dodecanal + O2 + 2 NADPH + 2 H+ <=> undecane + formate + H2O + 2 NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
myrcene + NADPH + H+ + O2 <=> (4R)-ipsdienol + NADP+ + H2O 1.14.14.31 ipsdienol synthase
–
Salicylaldehyde + NADP+ + H2O <=> salicylate + NADPH 1.2.1.7 benzaldehyde dehydrogenase (NADP+)
–
(6E)-8-oxogeranial + NADPH + H+ <=> nepetalactol + iridodial + NADP+ 1.3.1.123 8-oxogeranial reductase
–
5,5-dimethyl-3-(3-fluorphenyl)-4-(4-methylsulphonyl)phenyl-2-(5H-furanone)-lactol + NADP+ <=> 5,5-dimethyl-3-(3-fluorphenyl)-4-(4-methylsulfonyl)phenyl-2-(5H-furanone)-lactone + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
(6S)-5,10-methylene-5,6,7,8-tetrahydropteroylpentaglutamate + NADP+ <=> (6S)-5,10-methylene-5,6,7,8-tetrahydropteroylpentaglutamate + NADPH + H+ 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
–
–
3-oxohexanoyl-CoA + NADPH <=> (3R)-hydroxyhexanoyl-CoA + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
2-oxocyclopentyl_acetic_acid + O2 + NADPH + H+ <=> (6-oxotetrahydro-2H-pyran-2-yl)acetic_acid + NADP+ + H2O 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
–
2-ethylcyclopentanone + O2 + NADPH + H+ <=> 6-ethyltetrahydro-2H-pyran-2-one + NADP+ + H2O 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
–
danusertib + NADPH + H+ + O2 <=> danusertib_N-oxide + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
2-oxo-DELTA3-4,5,5-trimethylcyclopentenylacetyl-CoA + O2 + NADPH + H+ <=> delta-lactone_of_5-hydroxy-3,4,4-trimethyl-A2-pimelyl-CoA + NADP+ + H2O 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
–
2-oxocyclopentyl_ethyl_acetate + O2 + NADPH + H+ <=> ethyl_(6-oxotetrahydro-2H-pyran-2-yl)acetate + NADP+ + H2O 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
–
chlorobenzene + NADPH + O2 <=> 4-Chlorophenol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
2-phenyl-1,2-benzothiazol-3(2H)-one + NADP+ <=> ebsulfur_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
crotonaldehyde + NADP+ <=> crotonate + NADPH 1.2.1.4 aldehyde dehydrogenase (NADP+)
–
cis-2-buten-1-ol + NADPH <=> crotonaldehyde + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
3-[(1R,4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NADP+ <=> 3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NADPH + H+ 1.3.1.B7
–
cycloartenone + NADPH <=> Cycloartenol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
daunorubicin + NADP+ <=> 7-deoxydaunomycinone + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
N,N-dimethylbutylamine + NADPH + H+ + O2 <=> N,N-dimethylbutylamine_N-oxide + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
–
thioredoxin_disulfide_h + NADPH <=> thioredoxin + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin-1_disulfide + NADPH <=> NADP+ + thioredoxin 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin + NADP+ <=> cytosolic_thioredoxin_disulfide + NADPH 1.8.1.B1
–
thioredoxin + NADP+ <=> human_thioredoxin_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
VX-680 + NADPH + H+ + O2 <=> tozasertib_N-oxide + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
–
octyl_4-chloro-3-oxobutanoate + NADPH <=> ethyl_(R)-4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
ethyl_4-chloro-3-oxobutanoate + NADPH + H+ <=> ethyl_(R)-4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
NADPH + H+ + 2,5-dimethyl-4-benzoquinone <=> NADP+ + 2,5-dimethyl-4-benzoquinone 1.6.5.10 NADPH dehydrogenase (quinone)
–
4-(phosphonooxy)-L-threonine + NADP+ <=> 3-amino-1-hydroxyacetone_1-phosphate + CO2 + NADPH 1.1.1.262 4-hydroxythreonine-4-phosphate dehydrogenase
–
4-(phosphonooxy)-L-threonine + NADP+ <=> 2-amino-3-oxo-4-phosphonooxybutyrate + NADPH 1.1.1.262 4-hydroxythreonine-4-phosphate dehydrogenase
–
an_aromatic_hydroxylamine + NADP+ <=> an_aromatic_nitric_oxide + NADPH + H+ 1.7.1.B2
1.7.1.B3
–
–
an_aromatic_nitric_oxide + NADP+ + H2O <=> an_aromatic_nitrate + NADPH + H+ 1.7.1.B2
1.7.1.B3
–
–
2,2,2-trifluoroacetophenone + NADPH + H+ <=> 2,2,2-trifluoro-1-phenylethanol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
3,6-anhydro-alpha-L-galactopyranose + NADP+ + H2O <=> 3,6-anhydro-alpha-L-galactonate + NADPH + H+ 1.2.1.92 3,6-anhydro-alpha-L-galactose dehydrogenase
–
1,5-dihydro-8-hydroxy-5-deazaflavin + NADP+ <=> 8-hydroxy-5-deazaflavin + NADPH + H+ 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
–
(R)-3-hydroxybutanoate + NADP+ <=> acetoacetate + NADPH 1.1.1.276 serine 3-dehydrogenase (NADP+)
1.1.1.30 3-hydroxybutyrate dehydrogenase
–
–
(R)-1-acetoxy-phenylacetone + NADPH + O2 <=> (R)-phenylacetylcarbinol + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
3-phenylpenta-2,4-dione + NADPH + O2 <=> (R)-phenylacetylcarbinol + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
2-Hydroxybiphenyl + NADPH + O2 <=> 2,3-Dihydroxybiphenyl + NADP+ + H2O 1.14.13.44 2-hydroxybiphenyl 3-monooxygenase
–
5beta-pregnane-21-ol-3,20-dione + NADPH + H+ <=> 5beta-pregnane-3beta,21-diol-20-one + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
D-xylosone + NADPH + H+ <=> D-Lyxose + NADP+ 1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
–
D-Lyxose + NADP+ <=> D-lyxono-1,4-lactone + NADPH 1.1.1.113 L-xylose 1-dehydrogenase
–
L-arabitol + NADP+ <=> L-xylulose + NADPH + H+ 1.1.1.12 L-arabinitol 4-dehydrogenase
1.1.1.138 mannitol 2-dehydrogenase (NADP+)
–
–
5alpha-dihydrotestosterone + NADPH + H+ <=> (5alpha,17beta)-androstane-3,17-diol + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
5beta-dihydrotestosterone + NADPH + H+ <=> (5beta,17beta)-androstane-3,17-diol + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
benzaldehyde + NADP+ + benzoyladenosine_5''-monophosphate + phosphate <=> benzoate + NADPH + ATP 1.2.1.30 carboxylate reductase (NADP+)
–
an_[amino_group_carrier_protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + phosphate + NADP+ <=> an_[amino_group_carrier_protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + NADPH + H+ 1.2.1.103 [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase
–
B
D-glyceraldehyde + phosphate + NADP+ <=> D-glyceroyl_phosphate + NADPH 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
–
beta-3-Methylaspartyl_phosphate + NADPH <=> beta-3-methylaspartate_4-semialdehyde + phosphate + NADP+ 1.2.1.11 aspartate-semialdehyde dehydrogenase
–
[amino_group_carrier_protein_LysW]-gamma-alpha-aminoadipate + NADPH + H+ <=> [amino_group_carrier_protein_LysW]-gamma-aminoadipic_semialdehyde + phosphate + NADP+ 1.2.1.103 [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase
–
[amino_group_carrier_protein_LysW]-gamma-aminoadipic_semialdehyde + phosphate + NADP+ <=> [amino_group_carrier_protein_LysW]-gamma-alpha-aminoadipate_phosphate + NADPH + H+ 1.2.1.103 [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase
–
7-oxodaunomycinone + NADPH + H+ <=> daunomycinone + NADP+ 1.1.1.362 aklaviketone reductase
–
1''-oxo-2''-L-hydroxypropyl-tetrahydropterin + NADP+ <=> sepiapterin + NADPH 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
1''-oxo-2''-D-hydroxypropyl-tetrahydropterin + NADP+ <=> D-sepiapterin + NADPH 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
2-Heptanone + NADPH + H+ <=> (S)-2-heptanol + NADP+ 1.1.1.219 dihydroflavonol 4-reductase
–
UDP-N-acetyl-D-glucosamine + NADP+ <=> UDP-2-acetamido-2-deoxy-alpha-D-glucuronate + NADPH 1.1.1.136 UDP-N-acetylglucosamine 6-dehydrogenase
–
androstanedione + NADPH + H+ <=> 3-hydroxyandrostan-17-one + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
5-(hydroxymethyl)-2-furaldehyde + NADPH + H+ <=> (furan-2,5-diyl)dimethanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
11-deoxy-beta-L-rhodomycinone + NADPH + H+ + O2 <=> beta-rhodomycinone + NADP+ + H2O 1.14.13.180 aklavinone 12-hydroxylase
–
L-leucine + H2O + NADP+ <=> 4-methyl-2-oxopentanoate + NH3 + NADPH + H+ 1.4.1.9 leucine dehydrogenase
–
2-oxoisovalerate + NADPH + NH3 <=> L-leucine + NADP+ + H2O 1.4.1.2 glutamate dehydrogenase
–
(R)-pulegone + NADPH + O2 <=> (+)-menthofuran + NADP+ + H2O 1.14.13.104 (+)-menthofuran synthase
–
7-dehydrositosterol + NADPH <=> sitosterol + NADP+ 1.3.1.21 7-dehydrocholesterol reductase
–
bicyclo[3.2.0]hept-2-en-6-one + NADPH + O2 <=> (1R,5S)-3-oxabicyclo-[3.3.0]oct-6-en-3-one + (1S,5R)-2-oxabicyclo-[3.3.0]oct-6-en-3-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
Chloroacetophenone + NADPH + H+ <=> (R)-2-chloro-1-phenylethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2,3-Pentanedione + NADPH + H+ <=> (R)-2-hydroxy-pentane-3-one + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.B4
–
–
(2Z)-3-(4-chlorophenyl)-3-cyanoprop-2-enoic_acid + NADPH <=> (R)-3-(4-chlorophenyl)-3-cyano-propanoic_acid + NADP+ 1.3.1.31 2-enoate reductase
–
(Z)-3-cyano-3-phenyl-propenoic_acid + NADPH + H+ <=> (R)-3-cyano-3-phenylpropanoic_acid + NADP+ 1.3.1.31 2-enoate reductase
–
ethyl_(2Z)-3-nitro-2-phenylprop-2-enoate + NADPH <=> ethyl_(2R)-3-nitro-2-phenylpropanoate + NADP+ 1.3.1.31 2-enoate reductase
–
2,3-Pentanedione + NADPH + H+ <=> (S)-2-hydroxy-pentane-3-one + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-hydroxypropionate + NADP+ <=> succinate_semialdehyde + NADPH 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
[(1E)-2-nitroprop-1-en-1-yl]benzene + NADPH <=> 1-phenyl-2-nitropropane + NADP+ 1.3.1.31 2-enoate reductase
–
10-nitro-octadec-9-enoic_acid + NADPH + H+ <=> 10-nitrostearic_acid + NADP+ 1.3.1.16 beta-nitroacrylate reductase
–
NADPH + H+ + 2 2-Hydroxy-1,4-naphthoquinone <=> NADP+ + 2 2-hydroxy-1,4-naphthosemiquinone 1.6.5.5 NADPH:quinone reductase
–
3,4-dihydronaphthalen-2(1H)-one + NADPH + H+ <=> 2-tetralol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + NADPH + H+ <=> dTDP-fucose + NADP+ 1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
–
(2E)-2-cyano-3-phenylprop-2-enoic_acid + NADPH <=> 2-cyano-3-phenylpropanoic_acid + NADP+ 1.3.1.31 2-enoate reductase
–
2,5-dichlorophenol + NADPH + O2 <=> 3,6-dichlorocatechol + NADP+ + H2O 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
–
8-hydroxy-2-tetralone + NADPH + H+ <=> 8-hydroxy-2-tetralol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
8-methoxy-2-tetralone + NADPH + H+ <=> 8-methoxy-2-tetralol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
9-nitro-octadec-9-enoic_acid + NADPH + H+ <=> 9-nitrostearic_acid + NADP+ 1.3.1.16 beta-nitroacrylate reductase
–
NADPH + H+ + 2 2,5-dibromo-3-methyl-6-isopropylbenzoquinone <=> NADP+ + 2 dibromothymosemiquinone 1.6.5.5 NADPH:quinone reductase
–
bupropion + NADPH + H+ <=> erythrohydrobupropion + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
ethyl_2-oxo-4-phenylbutanoate + NADPH + H+ <=> ethyl_(2S)-2-hydroxy-4-phenylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.B4
–
–
ethyl_4,4,4-trifluoro-3-oxobutanoate + NADPH + H+ <=> ethyl_(3R)-4,4,4-trifluoro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
ethyl_3-oxovalerate + NADPH + H+ <=> ethyl_(S)-3-hydroxypentanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.283 methylglyoxal reductase (NADPH)
–
–
ethyl_2-oxo-3-phenylpyruvate + NADPH + H+ <=> ethyl_2-hydroxy-3-phenylpyruvate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
palmitoyl-CoA + NADP+ <=> hexadecanal + CoA + NADPH 1.2.1.50 long-chain acyl-protein thioester reductase
–
trans-2-hexadecenoyl-CoA + NADPH + H <=> palmitoyl-CoA + NADP+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + NADPH + H+ <=> dTDP-quinovose + NADP+ 1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
–
Isobutyraldehyde + NADP+ <=> Isobutyrate + NADPH 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
3 Toluene + 3 NADPH + 3 H+ + 3 O2 <=> o-Cresol + m-cresol + p-Cresol + 3 NADP+ + 3 H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
p-Cresol + NADP+ + H2O <=> 4-Hydroxybenzyl_alcohol + NADPH 1.17.9.1 4-methylphenol dehydrogenase (hydroxylating)
–
4-methyl-5-nitrocatechol + O2 + NADPH + H+ <=> 2-hydroxy-5-methylquinone + H2O + NADP+ 1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
–
protoasukamycin + NADPH + H+ + O2 <=> 4-hydroxyprotoasukamycin + NADP+ + H2O 1.14.13.215 protoasukamycin 4-monooxygenase
–
(4E,6E)-2-methyl-3-oxoocta-4,6-dienoyl-S-ACP + NADPH + H+ <=> (4E,6E)-2-methyl-3-hydroxyocta-4,6-dienoyl-S-ACP + NADP+ 2.3.1.161 lovastatin nonaketide synthase
–
3-oxohexanoyl-N-acetylcysteamine + NADPH + H+ <=> 3-hydroxyhexanoyl-N-acetylcysteamine + NADP+ 2.3.1.161 lovastatin nonaketide synthase
–
2-methyl-3-oxohexanoyl-N-acetylcysteamine + NADPH + H+ <=> 2-methyl-3-hydroxyhexanoyl-N-acetylcysteamine + NADP+ 2.3.1.161 lovastatin nonaketide synthase
–
3-Nitro-4-methoxybenzoate + NADPH + O2 <=> 4-Hydroxy-3-nitrobenzoate + NADP+ + H2O + formaldehyde 1.14.99.15 4-methoxybenzoate monooxygenase (O-demethylating)
–
veratric_acid + NADPH + O2 <=> vanillic_acid + NADP+ + H2O + formaldehyde 1.14.13.82 vanillate monooxygenase
–
methyl_tert-butyl_ether + NADPH + H+ + O2 <=> tert-butanol + NADP+ + H2O + formaldehyde 1.14.15.3 alkane 1-monooxygenase
–
tert-amyl_methyl_ether + NADPH + H+ + O2 <=> 2-methyl-2-butanol + NADP+ + H2O + formaldehyde 1.14.15.3 alkane 1-monooxygenase
–
7-methylxanthine + O2 + NADH + H+ <=> xanthine + formaldehyde + NADP+ 1.14.13.128 7-methylxanthine demethylase
–
paraxanthine + 2 O2 + 2 NADPH + 2 H+ <=> xanthine + 2 NADP+ + 2 H2O + 2 formaldehyde 1.14.13.128 7-methylxanthine demethylase
–
Theobromine + O2 + NADH + H+ <=> 3-Methylxanthine + formaldehyde + NADP+ 1.14.13.128 7-methylxanthine demethylase
–
4-Methoxybenzoate + NADPH + O2 <=> 4-hydroxybenzoate + NADP+ + H2O + formaldehyde 1.14.99.15 4-methoxybenzoate monooxygenase (O-demethylating)
–
1,1-Dimethylhydrazine + NADPH + O2 <=> formaldehyde + methylhydrazine + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
vanillic_acid + NADPH + O2 <=> 3,4-dihydroxybenzoate + NADP+ + H2O + formaldehyde 1.14.13.82 vanillate monooxygenase
–
Isovanillate + NADPH + O2 <=> 3,4-dihydroxybenzoate + NADP+ + H2O + formaldehyde 1.14.13.82 vanillate monooxygenase
–
Nicotine + NADPH + O2 + H+ <=> Nornicotine + formaldehyde + NADP+ + H2O 1.14.14.B11
–
veratric_acid + NADPH + O2 <=> Isovanillate + NADP+ + H2O + formaldehyde 1.14.13.82 vanillate monooxygenase
–
prostaglandin_E1 + NADP+ <=> 15-keto-prostaglandin_E1 + NADPH + H+ 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
–
(2Z,6Z)-farnesol + NADP+ <=> (2Z,6Z)-farnesal + NADPH + H+ 1.1.1.216 farnesol dehydrogenase (NADP+)
–
1,3,6-trihydroxynaphthalene + NADPH + H+ <=> (R)-8-deoxyscytalone + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
2-bromo-4-chlorophenol + NADPH + O2 <=> 3-bromo-5-chlorocatechol + NADP+ + H2O 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
–
4-hydroxy-2-hexenal + NADPH + H+ <=> 4-hydroxyhexadecanal + NADP+ 1.3.1.27 2-hexadecenal reductase
–
5beta-dihydrocorticosterone + NADPH + H+ <=> (3beta,5beta,11beta)-3,11,21-trihydroxypregnan-20-one + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
4-bromo-2-chlorophenol + NADPH + O2 <=> 5-bromo-3-chlorocatechol + NADP+ + H2O 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
–
5-hydroxy-2-tetralone + NADPH + H+ <=> 5-hydroxy-2-tetralol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
5-methoxy-2-tetralone + NADPH + H+ <=> 5-methoxy-2-tetralol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
5alpha-pregnane-21-ol-3,20-dione + NADPH + H+ <=> 5alpha-pregnane-3beta,21-diol-20-one + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
3,7-Diketo-5beta-cholanoic_acid + NADPH + H+ <=> 5beta-cholanic_acid-3beta-ol-7-one + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
5beta-hydroxy-5beta_cholanic_acid + NADP+ <=> 3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
5beta-pregnane-20alpha-ol-3-one + NADPH + H+ <=> 5beta-pregnane-3beta,20-diol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
5beta-pregnane-3beta,20beta-diol + NADP+ <=> 5beta-pregnan-20alpha-ol-3-one + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
6-hydroxy-2-tetralone + NADPH + H+ <=> 6-hydroxy-2-tetralol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
6-methoxy-2-tetralone + NADPH + H+ <=> 6-methoxy-2-tetralol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
7-hydroxy-2-tetralone + NADPH + H+ <=> 7-hydroxy-2-tetralol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
7-methoxy-2-tetralone + NADPH + H+ <=> 7-methoxy-2-tetralol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
isoamyl_pyruvate + NADPH + H+ <=> isoamyl_lactate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
dehydrodiconiferyl_alcohol + NADPH <=> isodihydrodehydrodiconiferyl_alcohol + NADP+ 1.3.1.45 2'-hydroxyisoflavone reductase
–
Methyl_pyruvate + NADPH + H+ <=> methyl_(2S)-2-hydroxypropanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-oxo-3-phenylpropanoate_methylester + NADPH + H+ <=> methyl_2-hydroxy-3-phenylpropanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
isodihydrodehydrodiconiferyl_alcohol + NADPH <=> tetrahydrodehydrodiconiferyl_alcohol + NADP+ 1.3.1.45 2'-hydroxyisoflavone reductase
–
2-methylcyclohexanone + NADPH + H+ <=> trans-2-methylcyclohexanol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
1-[3-(benzylselanyl)phenyl]ethanone + NADPH + H+ + O2 <=> 1-(3-(benzylseleninyl)phenyl)ethanone + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
1-[3-(methylselanyl)phenyl]ethanone + NADPH + H+ + O2 <=> 1-(3-(methylseleninyl)phenyl)ethanone + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
1-[4-(benzylselanyl)phenyl]ethanone + NADPH + H+ + O2 <=> 1-(4-(benzylseleninyl)phenyl)ethanone + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
1-[4-(methylselanyl)phenyl]ethanone + NADPH + H+ + O2 <=> 1-(4-(methylseleninyl)phenyl)ethanone + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
tabersonine + NADPH + H+ <=> 2,3-dihydro-3-hydroxytabersonine + NADP+ 1.1.99.41 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase
–
2-acetolactate + NADPH + H+ <=> 2,3-dihydroxy-2-methylbutanoate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
acetolactate + NADPH + H+ <=> 2,3-dihydroxy-2-methylbutanoate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 24,25-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
DELTA5,7-avenasterol + NADPH + H+ <=> DELTA5,7-sitosterol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
phenylacetone + NADPH <=> 2-phenylethanol + NADP+ 1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
–
acetophenone + NADPH + H+ <=> 2-phenylethanol + NADP+ 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.B4
–
–
retronecine + NADPH + H+ + O2 <=> retronecine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
5alpha-Androstane-3beta,17beta-diol + NADPH + H+ + O2 <=> 5alpha-androstane-3beta,7alpha,17beta-triol + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
7-oxo-5alpha-androstane-3beta,17beta-diol + NADPH <=> 5alpha-androstane-3beta,7alpha,17beta-triol + 5alpha-androstane-3beta,7alpha,17beta-triol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
5alpha-androstane-3beta,7alpha,17beta-triol + NADP+ <=> 5alpha-androstane-3beta,7beta,17beta-triol + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
(+/-)-pinoresinol + NADPH + H+ <=> (+)-lariciresinol + NADP+ 1.23.1.1 (+)-pinoresinol reductase
–
7-oxo-dehydroepiandrosterone + 2 NADPH + 2 H+ <=> 7alpha-hydroxydehydroepiandrosterone + 7beta-hydroxydehydroepiandrosterone + 2 NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
dehydroepiandrosterone + NADPH + H+ + O2 <=> 7alpha-hydroxydehydroepiandrosterone + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
7alpha-hydroxydehydroepiandrosterone + NADP+ <=> 7beta-hydroxydehydroepiandrosterone + 7-oxo-dehydroepiandrosterone + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
coniferyl_aldehyde + NADP+ <=> dihydroconiferyl_aldehyde + NADPH + H+ 1.3.1.102 2-alkenal reductase (NADP+)
–
D-erythro-C2:0_dihydroceramide + NADPH + H+ + O2 <=> N-acetyl-4-hydroxysphinganine + NADP+ + H2O 1.14.18.5 sphingolipid C4-monooxygenase
–
2-methyl-3-geranyl-4(1H)-quinolinone + NADPH + H+ + O2 <=> 3-[(3,7-dimethylocta-1,6-dien-3-yl)oxy]-2-methyl-2,3-dihydroquinolin-4(1H)-one + NADP+ + H2O 1.14.13.222 aurachin C monooxygenase/isomerase
–
2-methyl-3-isoprenyl-4(1H)-quinolinone + NADPH + H+ + O2 <=> 2-methyl-3-[(2-methylbut-3-en-2-yl)oxy]-2,3-dihydroquinolin-4(1H)-one + NADP+ + H2O 1.14.13.222 aurachin C monooxygenase/isomerase
–
2 2,3-dimethyl-4(1H)-quinolinone + NADPH + H+ + O2 <=> 3-hydroxy-2-[(3-hydroxy-3-methyl-4-oxo-1,2,3,4-tetrahydroquinolin-2-yl)methyl]-3-methylquinolin-4(3H)-one + NADP+ + H2O 1.14.13.222 aurachin C monooxygenase/isomerase
–
(4S)-5,5,5-trifluoro-4-hydroxy-4-phenylpentan-2-one + NADPH + H+ <=> (2S)-1,1,1-trifluoro-2-phenylpentane-2,4-diol + NADP+ 1.1.1.219 dihydroflavonol 4-reductase
–
Pyridine + NADPH + O2 <=> Pyridine_N-oxide + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
Ubiquinone-10 + NADPH <=> coenzyme_Q10 + NADP+ 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
–
ferrocyanide + NADPH <=> ferricyanide + NADP+ 1.12.1.2 hydrogen dehydrogenase
–
glutathione_amide_disulfide + NADPH + H+ <=> 2 glutathione_amide + NADP+ 1.8.1.16 glutathione amide reductase
–
proviolacein + NADPH + O2 <=> violacein + NADP+ + H2O 1.14.13.224 violacein synthase
–
3,4-dihydronaphthalen-2(1H)-one + NADPH + H+ <=> (2S)-1,2,3,4-tetrahydronaphthalen-2-ol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
8-methoxy-2-tetralone + NADPH + H+ <=> (2R)-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-ol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
6-methoxy-2-tetralone + NADPH + H+ <=> (2S)-6-methoxy-1,2,3,4-tetrahydronaphthalen-2-ol + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
2,3-dihydronaphthalene-1,4-dione + NADPH + H+ <=> (4S)-4-hydroxy-3,4-dihydronaphthalen-1(2H)-one + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
5-hydroxy-2,3-dihydronaphthalene-1,4-dione + NADPH + H+ <=> (4S)-4,8-dihydroxy-3,4-dihydronaphthalen-1(2H)-one + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
3-acetylpyridine + NADPH + H+ <=> (S)-(1-pyridin-3yl)ethanol + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
3-Propionylpyridine + NADPH + H+ <=> (S)-(1-pyridin-3yl)propanol + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
1-(thiophen-2-yl)-ethanone + NADPH + H+ <=> (1S)-1-(thiophen-2-yl)ethanol + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
furan-2-yl-acetic_acid + NADPH + H+ <=> (1S)-1-(furan-2-yl)ethanol + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
4-acetylbenzonitrile + NADPH + H+ <=> 4-[(1S)-1-hydroxyethyl]benzonitrile + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
4-Nitroacetophenone + NADPH + H+ <=> (1S)-1-(4-nitrophenyl)ethanol + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
oxidized_iodonitrotetrazolium_violet + NADPH <=> reduced_iodonitrotetrazolium_chloride + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
–
D-erythronate + NADP+ <=> 2-dehydro-D-erythronate + NADPH + H+ 1.1.1.410 D-erythronate 2-dehydrogenase
–
4-hydroxy-2-nonenal + NADPH <=> 1,4-dihydroxynon-2-ene + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.300 NADP-retinol dehydrogenase
–
–
1-hydroxynonen-4-one + NADPH <=> 1,4-dihydroxynon-2-ene + NADP+ 1.1.1.21 aldose reductase
–
rac-2-methyl-1-indanone + NADPH + H+ + O2 <=> (R)-3-methyl-3,4-dihydrocoumarin + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
1-acetyl-4-(methylsulfanyl)benzene + NADPH + H+ + O2 <=> (R,S)-1-[4-(methylsulfanyl)phenyl]ethanone_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
4-(methylsulfanyl)phenol + NADPH + H+ + O2 <=> (R,S)-4-(methylsulfanyl)phenol_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
ethyl_2-chloro-3-oxobutanoate + NADPH + H+ <=> (S)-ethyl_2-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
methyl_2-chloro-3-oxobutanoate + NADPH + H+ <=> (S)-methyl_2-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
methyl_4-chloro-3-oxobutanoate + NADPH <=> methyl_(S)-4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.B3
–
–
4-hydroxy-2-nonenal + NADPH + H+ <=> 1,4-dihydroxynonane + NADP+ 1.1.1.21 aldose reductase
–
p-hydroxyphenylacetaldoxime + NADPH + H+ + 2-mercaptoethanol <=> (Z)-2-hydroxyethyl_N,4-dihydroxybenzene-1-carboximidothioate + NADP+ + H2O 1.14.14.45 aromatic aldoxime N-monooxygenase
–
20-hydroxyvitamin_D3 + NADPH + O2 <=> 1alpha,20-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.15.18 calcidiol 1-monooxygenase
–
secalciferol + NADPH + O2 <=> 1alpha,24,25-trihydroxyvitamin_D3 + NADP+ + H2O 1.14.15.18 calcidiol 1-monooxygenase
–
4-methyl-2-oxopentanoate + NH3 + NADPH + H+ <=> D-Leu + H2O + NADP+ 1.4.99.6 D-arginine dehydrogenase
–
D-threonine + NADP+ <=> D-2-amino-3-oxobutanoic_acid + NADPH 1.1.1.276 serine 3-dehydrogenase (NADP+)
–
ethyl_2-methylacetoacetate + NADPH + H+ <=> ethyl_3-hydroxy-2-methylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
L-lysine + NADP+ + H2O <=> (S)-2-amino-6-oxohexanoate + NADPH + H+ + NH3 1.4.1.18 lysine 6-dehydrogenase
–
L-lysine + NADP+ <=> 2-aminoadipate_6-semialdehyde + NADPH 1.4.1.18 lysine 6-dehydrogenase
–
stigmasterol + O2 + NADPH + H+ <=> stigmast-5,7,22-trien-3beta-ol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
(2E)-5-methylhex-2-enoyl-CoA + NADPH + CO2 + H+ <=> (2S)-(3-methylbutyl)propanedioyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
2-octenoyl-CoA + NADPH + CO2 + H+ <=> (2S)-2-carboxyoctanoyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
(2E)-6-methyloct-2-enoyl-CoA + NADPH + CO2 + H+ <=> (2S)-2-carboxy-6-methyloctanoyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
(2E)-5-chloropent-2-enoyl-CoA + NADPH + CO2 + H+ <=> (2S)-2-carboxy-5-chloropentanoyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
(2E)-hept-2-en-6-ynoyl-CoA + NADPH + CO2 + H+ <=> (2S)-2-craboxy-hept-6-ynoyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
trypanothione + NADPH <=> trypanothione + NADP+ 1.8.1.7 glutathione-disulfide reductase
–
(2E)-3-cyclohexylprop-2-enoyl-CoA + NADPH + CO2 + H+ <=> (2S)-2-carboxy-3-cyclohexylpropanoyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
cinnamoyl-CoA + NADPH + CO2 + H+ <=> (2S)-2-carboxy-3-phenylpropionyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
4-coumaroyl-CoA + NADPH + CO2 + H+ <=> (2S)2-carboxy-3-(4-hydroxyphenyl)propionyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
erythrose + NADPH <=> glycerol + NADP+ 1.1.1.20 glucuronolactone reductase
–
Hydroxyacetone + NADPH + H+ <=> glycerol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
diphosphate + NAD+ <=> phosphate + NADP+ 2.7.1.23 NAD+ kinase
–
geranylgeranyl_diphosphate + (2E,6E)-farnesyl_diphosphate + NADPH + H+ <=> (6E,10E,14E,18E,22E)-2,6,10,14,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaene + 2 diphosphate + NADP+ 2.5.1.148 lycopaoctaene synthase
–
UTP + 3-hydroxypropionate + CoA + NADPH <=> UMP + diphosphate + NADP+ + propionyl-CoA 6.2.1.17 propionate---CoA ligase
–
GTP + 3-hydroxypropionate + CoA + NADPH <=> GMP + diphosphate + NADP+ + propionyl-CoA 6.2.1.17 propionate---CoA ligase
–
2 (2E,6E)-farnesyl_diphosphate + NADPH + H+ <=> diphosphate + presqualene_diphosphate + NADP+ 2.5.1.103 presqualene diphosphate synthase
–
3-desmethyl_farnesyl_diphosphate + NADPH <=> 10-Demethylsqualene + NADP+ + diphosphate 2.5.1.21 squalene synthase
–
2-Methylfarnesyl_diphosphate + NADPH <=> 11-Methylsqualene + NADP+ + diphosphate 2.5.1.21 squalene synthase
–
10,11-Dihydrofarnesyl_diphosphate + NADPH <=> 2,3,22,23-Tetrahydrosqualene + NADP+ + diphosphate 2.5.1.21 squalene synthase
–
(E,E)-7-Desmethylfarnesyl_diphosphate + NADPH <=> 6,19-Didesmethylsqualene + NADP+ + diphosphate 2.5.1.21 squalene synthase
–
geranylgeranyl_diphosphate + NADPH <=> Lycopersene + NADP+ + diphosphate 2.5.1.148 lycopaoctaene synthase
–
amorpha-4,11-diene + O2 + NADPH + H+ <=> artemisinic_alcohol + NADP+ + H2O 1.14.13.158 amorpha-4,11-diene 12-monooxygenase
–
2-aminobutanoate + H2O + NADP+ <=> 2-oxobutyrate + NH3 + NADPH 1.4.1.3 glutamate dehydrogenase [NAD(P)+]
–
(2E,4E,6E,10Z)-4-methyl-11-[2-[(1R,2S)-2-methylcyclopropyl]-4,5-dihydro-1,3-thiazol-4-yl]undeca-2,4,6,10-tetraenoyl-[acyl-carrier-protein] + NADPH + H+ <=> (2E,4E,6E,10Z)-4-methyl-11-[2-[(1R,2S)-2-methylcyclopropyl]-4,5-dihydro-1,3-thiazol-4-yl]undeca-4,6,10-trienoyl-[acyl-carrier-protein] + NADP+ 1.3.1.B14
–
6-methyl-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2R)-2-methylpiperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
2-phenyl-1-pyrroline + NADPH + H+ <=> (2S)-2-phenylpyrrolidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
methyl_p-tolyl_sulfide + NADPH + H+ + O2 <=> (S)-methyl_4-tolyl_sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
5-methoxy-2,3,3-trimethyl-3H-indole + NADPH + H+ <=> (2R)-5-methoxy-2,3,3-trimethyl-2,3-dihydro-1H-indole + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
1,2,3,3,5-pentamethyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-1,2,3,3,5-pentamethyl-2,3-dihydro-1H-indole + NADP+ + I- 1.5.1.48 2-methyl-1-pyrroline reductase
–
2,3,3-trimethyl-1-propyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-2,3,3-trimethyl-1-propyl-2,3-dihydro-1H-indole + NADP+ + I- 1.5.1.48 2-methyl-1-pyrroline reductase
–
1-methyl-3,4-dihydroisoquinoline + NADPH + H+ <=> (1S)-1-methyl-1,2,3,4-tetrahydroisoquinoline + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
1-ethyl-2,3,3-trimethyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-1-ethyl-2,3,3-trimethyl-2,3-dihydro-1H-indole + NADP+ + I- 1.5.1.48 2-methyl-1-pyrroline reductase
–
1,2,3,3-tetramethyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-1,2,3,3-tetramethyl-2,3-dihydro-1H-indole + NADP+ + I- 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-methyl-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-methylpiperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
chanoclavine-I_aldehyde + NADPH + H+ <=> agroclavine + NADP+ 1.5.1.46 agroclavine dehydrogenase
–
TDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ <=> TDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+ 1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
–
protopanaxadiol + NADPH + H+ + O2 <=> protopanaxatriol + NADP+ + H2O 1.14.13.184 protopanaxadiol 6-hydroxylase
–
geranylgeranyl_diphosphate + phythyl_diphoshate + NADPH + H+ <=> lycopaoctaene + lycopadiene + lycopapentaene + NADP+ 2.5.1.148 lycopaoctaene synthase
–
2 geranylgeranyl_diphosphate + NADPH + H+ <=> lycopaoctaene + NADP+ 2.5.1.148 lycopaoctaene synthase
–
2-heptyl-4(1H)-quinolone + NADPH + H+ + O2 <=> 2-heptyl-3-hydroxy-4(1H)-quinolone + NADP+ + H2O 1.14.13.182 2-heptyl-3-hydroxy-4(1H)-quinolone synthase
–
stigmastanol + O2 + NADPH + H+ <=> 5alpha-24-ethylcholest-7-en-3beta-ol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
22-cholesten-3beta-ol + NADPH + H+ <=> 7,22-cholestadiene-3beta-ol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
d-isomenthone + NADPH <=> (+)-isomenthol + NADP+ 1.1.1.208 (+)-neomenthol dehydrogenase
–
myrcene + NADPH + H+ + O2 <=> ipsdienol + NADP+ + H2O 1.14.14.31 ipsdienol synthase
–
1-Butene + NADPH + O2 <=> 1,2-Epoxybutane + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
D-erythro-N-hexanoyl-sphinganine + NADPH + H+ + O2 <=> N-hexanoyl-4-hydroxysphinganine + NADP+ + H2O 1.14.18.5 sphingolipid C4-monooxygenase
–
N-octanoylsphinganine + NADPH + H+ + O2 <=> N-octanoyl-4-hydroxysphinganine + NADP+ + H2O 1.14.18.5 sphingolipid C4-monooxygenase
–
2,4-Dimethoxybenzyl_alcohol + NADP+ <=> 2,4-Dimethoxybenzaldehyde + NADPH + H+ 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
2,3,3,5-tetramethyl-3H-indole + NADPH + H+ <=> (2R)-2,3,3,5-tetramethyl-2,3-dihydro-1H-indole + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
2,3,3-trimethyl-5-nitro-3H-indole + NADPH + H+ <=> (2R)-2,3,3-trimethyl-5-nitro-2,3-dihydro-1H-indole + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
5-bromo-2,3,3-trimethyl-3H-indole + NADPH + H+ <=> (2R)-5-bromo-2,3,3-trimethyl-2,3-dihydro-1H-indole + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
2-Methylbenzaldehyde + NADPH <=> 2-Methylbenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
(2E)-3-methylpent-2-enal + NADPH + H+ <=> 2-Methylpentanal + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
–
(R)-1-phenyl-2-propanol + NADP+ <=> phenylacetone + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-methyl-2-pentenal + NADPH + H+ <=> (2E)-2-methylpent-2-en-1-ol + NADP+ 1.1.1.1 alcohol dehydrogenase
–
2-decenal + NADPH + H+ <=> (2E)-dec-2-en-1-ol + NADP+ 1.1.1.1 alcohol dehydrogenase
–
ethyl_pyruvate + NADPH + H+ <=> (R)-ethyl_2-hydroxypropanoate + NADP+ 1.1.1.1 alcohol dehydrogenase
–
1-phenyl-2-butanone + NADPH + H+ <=> (S)-1-phenyl-2-butanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
3-Deoxy-D-galactose + NADP+ <=> D-galactono-1,5-lactone + NADPH 1.1.1.120 galactose 1-dehydrogenase (NADP+)
–
anhydrotetracycline + NADPH + H+ + O2 <=> 11a-hydroxyanhydrotetracycline + NADP+ + H2O 1.14.13.231 tetracycline 11a-monooxygenase
–
chlortetracycline + NADPH + H+ + O2 <=> 11a-hydroxychlorotetracycline + NADP+ + H2O 1.14.13.231 tetracycline 11a-monooxygenase
–
2-aceto-2-hydroxybutyrate + NADPH + H+ <=> 2,3-dihydroxy-2-ethyl-butanoate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
2-phenyl-1-pyrroline + NADPH + H+ <=> (2R)-5-fluoro-2,3,3-trimethyl-2,3-dihydro-1H-indole + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
(2E)-4-methylhex-2-enoyl-CoA + NADPH + CO2 + H+ <=> [(2R)-2-methylbutyl]propanedioyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
5-chloro-2,3,3-trimethyl-3H-indole + NADPH + H+ <=> (2R)-5-chloro-2,3,3-trimethyl-2,3-dihydro-1H-indole + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-keto-prostaglandin_F1alpha + NADP+ <=> 6,15-diketo-prostaglandin_F1alpha + NADPH 1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
–
2,3,3-trimethyl-3H-indole + NADPH + H+ <=> (2R)-2,3,3-trimethyl-2,3-dihydro-1H-indole + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
9alpha-Fluorocortisone + NADPH <=> 9alpha-Fluorocortisol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
5-fluoro-1,2,3,3-tetramethyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-5-fluoro-1,2,3,3-tetramethyl-2,3-dihydro-1H-indole + NADP+ + I- 1.5.1.48 2-methyl-1-pyrroline reductase
–
1,1,2,3-tetramethyl-1H-benzo[e]indol-3-ium_iodide + NADPH + H+ <=> (-)-1,1,2,3-tetramethyl-2,3-dihydro-1H-benzo[e]indole + NADP+ + I- 1.5.1.48 2-methyl-1-pyrroline reductase
–
2-cyclohexyl-1-pyrroline + NADPH + H+ <=> (2S)-2-cyclohexylpyrrolidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-phenyl-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-phenylpiperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-(4-methoxyphenyl)-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-(4-methoxyphenyl)piperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-(4-fluorophenyl)-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-(4-fluorophenyl)piperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-cyclohexyl-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (-)-2-cyclohexylpiperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-(3-methoxyphenyl)-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-(3-methoxyphenyl)piperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-(2-methoxyphenyl)-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-(2-methoxyphenyl)piperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-propyl-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2R)-2-propylpiperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-(propan-2-yl)-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-(propan-2-yl)piperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-(thiophen-2-yl)-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (-)-2-(thiophen-2-yl)piperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-benzyl-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-benzylpiperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-(naphthalen-2-yl)-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (-)-2-(naphthalen-2-yl)piperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
1-methyl-3,4-dihydroisoquinoline + NADPH + H+ <=> (1R)-1-methyl-1,2,3,4-tetrahydroisoquinoline + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
1,2-dimethyl-3,4-dihydroisoquinolin-2-ium + NADPH + H+ <=> (1R)-1,2-dimethyl-1,2,3,4-tetrahydroisoquinoline + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
5-(4-methoxyphenyl)-3,4-dihydro-2H-pyrrole + NADPH + H+ <=> (2S)-2-(4-methoxyphenyl)pyrrolidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
5-(4-fluorophenyl)-3,4-dihydro-2H-pyrrole + NADPH + H+ <=> (2S)-2-(4-fluorophenyl)pyrrolidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
D-aldose + NADPH <=> alditol + NADP+ 1.1.1.19 glucuronate reductase
–
L-idose + NADPH + H+ <=> alditol + NADP+ 1.1.1.21 aldose reductase
–
3-Cyanopyridine + H2O + NADP+ <=> 6-hydroxy-3-cyanopyridine + NADPH + H+ 1.17.1.5 nicotinate dehydrogenase
–
1-(2-chlorophenyl)ethanol + NADP+ <=> 1-(2-chlorophenyl)ethanone + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
2-(1-imidazolyl)-1-(4-methoxyphenyl)-2-methyl-1-propanone + NADPH + H+ <=> 2-(1H-imidazol-1-yl)-1-(4-methoxyphenyl)-2-methylpropan-1-ol + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
D-Lyxose + NADPH <=> D-arabitol + NADP+ 1.1.1.21 aldose reductase
–
L-Lyxose + NADPH <=> D-arabitol + NADP+ 1.1.1.21 aldose reductase
–
L-arabinose + NADPH <=> D-arabitol + NADP+ 1.1.1.21 aldose reductase
1.1.1.307 D-xylose reductase
–
–
bacteriopheophytin_a + 3 NADP+ <=> geranylgeranyl-bacteriopheophytin_a + 3 NADPH + 3 H+ 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase
–
methyl_4-bromo-3-oxobutanoate + NADPH + H+ <=> methyl_(S)-4-bromo-3-hydroxybutanoate + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-oxoadipate + NADPH + NH3 <=> L-2-aminoadipate + NADP+ + H2O 1.4.1.4 glutamate dehydrogenase (NADP+)
–
delphinidin + 2 NADPH + 2 H+ <=> (-)-gallocatechin + (+)-epigallocatechin + 2 NADP+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
–
2,2-difluoro-1-phenylethanone + NADPH + H+ <=> (1S)-2,2-difluoro-1-phenylethanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
1-(4-chlorophenyl)-2-fluoroethanone + NADPH + H+ <=> (1S)-2-fluoro-1-(4-chlorophenyl)ethanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-fluoro-1-(4-fluorophenyl)ethanon + NADPH + H+ <=> (1S)-2-fluoro-1-(4-fluorophenyl)ethanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-fluoro-1-(4-iodophenyl)ethanone + NADPH + H+ <=> (1S)-2-fluoro-1-(4-iodophenyl)ethanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-fluoro-1-phenylethanone + NADPH + H+ <=> (1S)-2-fluoro-1-phenylethanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
3-methyl-3-pentanol + NADPH + H+ + O2 <=> 3-methyl-1-penten-3-ol + NADP+ + 2 H2O 1.14.19.48 tert-amyl alcohol desaturase
–
ethylene + NADPH + O2 <=> Epoxyethane + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
5-O-trityl-alpha,beta-D-ribose + NADP+ + H2O <=> 5-O-trityl-D-ribono-1,4-lactone + NADPH + H+ 1.1.1.115 ribose 1-dehydrogenase (NADP+)
–
N-(3R)-1-azabicyclo[2.2.2]oct-3-ylfuro[2,3-c]pyridine-5-carboxamide + NADPH + H+ + O2 <=> (R)-3-(furo[2,3-c]pyridine-5-carboxamido)quinuclidine_1-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
5-[[4-(diethylamino)butyl]amino]-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one + NADPH + H+ + O2 <=> N,N-diethyl-2-((8-hydroxy-6-oxo-6H-imidazo[4,5,1-de]acridin-5-yl)amino)ethan-1-amine_oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
S-methyl_N,N-diethyldithiocarbamate + NADPH + H+ + O2 <=> (diethylnitroryl)(methylsulfanyl)methanethione + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
GSK5182 + NADPH + H+ + O2 <=> (Z)-2-(4-(5-hydroxy-1-(4-hydroxyphenyl)-2-phenylpent-1-en-1-yl)phenoxy)-N,N-dimethylethan-1-amine_oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
lorcaserin + NADPH + H+ + O2 <=> lorcaserin_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
(S)-metamphetamine + NADPH + H+ + O2 <=> (S)-metamphetamine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
(R)-metamphetamine + NADPH + H+ + O2 <=> (R)-metamphetamine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
VX-680 + NADPH + H+ + O2 <=> MK-0457_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
quazepam + NADPH + H+ + O2 <=> 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
SNI-2011 + NADPH + H+ + O2 <=> SNI-2011_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
contezolid + NADPH + H+ + O2 <=> contezolid_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
Trifluoperazine + NADPH + H+ + O2 <=> 2,3,4-trifluoropyridine_1-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
9-hydroxy-5,6-dimethyl-N-(2-(dimethylamino)ethyl)-6H-pyrido(4,3-B)-carbazole-1-carboxamide + NADPH + H+ + O2 <=> 2-(9-hydroxy-5,6-dimethyl-6H-pyrido[4,3-b]carbazole-1-carboxamido)-N,N-dimethylethan-1-amine_oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
olanzapine + NADPH + H+ + O2 <=> 1-methyl-4-(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)piperazine_1-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
moclobemide + NADPH + H+ + O2 <=> moclobemide_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
loxapine + NADPH + H+ + O2 <=> 4-(2-chlorodibenzo[b,f][1,4]oxazepin-11-yl)-1-methylpiperazine_1-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
L-775,606 + NADPH + H+ + O2 <=> 4-(3-(5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl)propyl)-1-(3-fluorophenethyl)piperazine_1-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
dasatinib + NADPH + H+ + O2 <=> 4-(6-((5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)-1-(2-hydroxyethyl)piperazine_1-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
N,N-diallyltryptamine + NADPH + H+ + O2 <=> N,N-diallyltryptamine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
methylene_blue + NADPH <=> reduced_methylene_blue + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
oxidized_methylene_blue + NADPH <=> reduced_methylene_blue + NADP+ 1.12.1.2 hydrogen dehydrogenase
1.5.1.30 flavin reductase (NADPH)
–
–
2-chloromaleylacetate + NADPH <=> maleylacetate + Cl- + NADP+ 1.3.1.32 maleylacetate reductase
–
Dichloromethane + NADPH + O2 <=> CO + Cl- + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
3,4,5-trichlorophenol + 2 NADPH + H+ + O2 <=> 2,6-dichlorohydroquinone + 2 NADP+ + Cl- + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
2,4,6-Trichlorophenol + NADPH + O2 <=> 2,6-dichlorohydroquinone + Cl- + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
2,3,5,6-Tetrachlorophenol + 2 NADPH + H+ + O2 <=> tetrachlorohydroquinone + 2 NADP+ + Cl- + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
3-chloro-L-tyrosine + NADP+ + Cl- <=> 3,5-dichloro-L-tyrosine + NADPH + H+ 1.21.1.1 iodotyrosine deiodinase
–
4-chlorophenylacetate + NADH + O2 + H2O <=> 3,4-Dihydroxyphenylacetate + Cl- + NADP+ 1.14.12.9 4-chlorophenylacetate 3,4-dioxygenase
–
2,3,4,5-Tetrachlorophenol + NADPH + O2 <=> 2,3,5-trichlorohydroquinone + Cl- + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
(R)-reticuline + NADPH + H+ + O2 <=> salutaridine + NADP+ + 2 H2O 1.14.21.4 salutaridine synthase
–
sepiapterin + NADPH <=> 1''-hydroxy-2''-oxopropyltetrahydropterin + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
1''-hydroxy-2''-oxopropyltetrahydropterin + NADP+ <=> tetrahydrobiopterin + NADPH 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
(1S)-Camphorquinone + NADPH + H+ <=> (1S)-Camphorquinone + NADP+ 1.6.5.10 NADPH dehydrogenase (quinone)
–
5alpha-cholesta-8,14-dien-3beta-ol + NADPH <=> 5alpha-cholesta-8-en-3beta-ol + NADP+ 1.3.1.70 Delta14-sterol reductase
–
Prostaglandin_B2 + NADP+ <=> 15-ketoprostaglandin_B2 + NADPH + H+ 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
–
Prostaglandin_D3 + NADP+ <=> 15-ketoprostaglandin_D3 + NADPH + H+ 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
–
(Z)-3-[(5-methoxy-3-oxo-2(3H)-benzofuranylidene)-methyl]benzoic_acid + NADPH <=> 3-[(5-methoxy-3-oxo-2,3-dihydro-1-benzofuran-2-yl)methyl]benzoic_acid + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
2-methyl-DL-serine + NADP+ <=> 2-amino-2-methyl-3-oxopropanoic_acid + NADPH 1.1.1.276 serine 3-dehydrogenase (NADP+)
–
tert-butyloxycarbonyl-L-cysteinylglycyl-3-dimethylaminopropylamide_disulfide + NADPH + H+ <=> 2 N-(tert-butoxycarbonyl)-L-cysteinyl-N-[3-(dimethylamino)propyl]glycinamide + NADP+ 1.8.1.12 trypanothione-disulfide reductase
–
N-benzyloxycarbonyl-L-cysteinylglycyl-3-dimethylaminopropylamide_disulfide + NADPH + H+ <=> 2 N-[(benzyloxy)carbonyl]-L-cysteinyl-N-[3-(dimethylamino)propyl]glycinamide + NADP+ 1.8.1.12 trypanothione-disulfide reductase
–
4-aminobutyryl-L-cysteinylglycyl-3-dimethylaminopropylamide_disulfide + NADPH + H+ <=> 2 N-(4-aminobutanoyl)-L-cysteinyl-N-[3-(dimethylamino)propyl]glycinamide + NADP+ 1.8.1.12 trypanothione-disulfide reductase
–
L-beta-aspartyl-L-cysteinylglycyl-3-dimethylaminopropylamide_disulfide + NADPH + H+ <=> 2 L-beta-aspartyl-L-cysteinyl-N-[3-(dimethylamino)propyl]glycinamide + NADP+ 1.8.1.12 trypanothione-disulfide reductase
–
L-gamma-glutamyl-L-cysteinylglycyl-3-dimethylaminopropylamide_disulfide + NADPH + H+ <=> 2 L-gamma-glutamyl-L-cysteinyl-N-[3-(dimethylamino)propyl]glycinamide + NADP+ 1.8.1.12 trypanothione-disulfide reductase
–
2-bromo-aceto-2-chlorophenone + NADPH <=> (R)-2-bromo-1-(2-chlorophenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-bromo-aceto-3-chlorophenone + NADPH <=> (R)-2-bromo-1-(3-chlorophenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-bromo-aceto-4-chlorophenone + NADPH <=> (R)-2-bromo-1-(4-chlorophenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2,3'-dichloroacetophenone + NADPH <=> (R)-2-chloro-1-(3-chlorophenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-fluoro-trans-trans-2,4-octadienoyl-CoA + NADPH <=> 2-fluoro-trans-3-octenoyl-CoA + NADP+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
oracin + NADPH + H+ <=> 11-dihydrooracin + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
–
–
2-hydroxyphenylacetate + NADPH + O2 <=> homogentisate + NADP+ + H2O 1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase
–
[(1E)-2-nitroprop-1-en-1-yl]benzene + NADP+ <=> [(3S)-3-nitrobutyl]benzene + NADPH + H+ 1.3.1.31 2-enoate reductase
1.6.99.1 NADPH dehydrogenase
–
–
L-cysteinylglycyl-3-dimethylaminopropylamide_disulfide + NADPH + H+ <=> 2 L-cysteinyl-N-[3-(dimethylamino)propyl]glycinamide + NADP+ 1.8.1.12 trypanothione-disulfide reductase
–
[4-(6-methylheptanoyl)-5-oxo-2,5-dihydrofuran-3-yl]methyl_dihydrogen_phosphate + NADPH + H+ <=> [(3S)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl_dihydrogen_phosphate + NADP+ 1.3.1.113 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase
–
prodeoxyviolacein + NADPH + O2 <=> deoxyviolacein + NADP+ + H2O 1.14.13.224 violacein synthase
–
methyl_3-oxopentanoate + NADPH + H+ <=> methyl_(3S)-3-hydroxypentanoate + NADP+ 1.1.1.283 methylglyoxal reductase (NADPH)
–
2-Octanone + NADPH + H+ + O2 <=> methyl_heptanoate + NADP+ + H2O 1.14.13.226 acetone monooxygenase (methyl acetate-forming)
–
(S)-3-quinuclidinol + NADP+ <=> 3-quinuclidinone + NADPH + H+ 1.1.1.B63
–
(R)-phenylacetylcarbinol + NADPH + H+ <=> (1R)-1-phenylpropane-1,2-diol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
1-(2-nitrophenyl)ethanone + NADPH + H+ <=> (1S)-1-(2-nitrophenyl)ethanol + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
(2R)-2-hydroxy-1-(4-methoxyphenyl)propan-1-one + NADPH + H+ <=> (2R)-1-(4-methoxyphenyl)propane-1,2-diol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
(S)-2-Hydroxy-1-(4-methoxy-phenyl)-propan-1-one + NADPH + H+ <=> (2S)-1-(4-methoxyphenyl)propane-1,2-diol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
(E)-ethyl_2-methyl-4-oxopent-2-enoate + NADP+ <=> ethyl_(2R)-2-methyl-4-oxopentanoate + NADPH + H+ 1.3.1.31 2-enoate reductase
1.6.99.1 NADPH dehydrogenase
–
–
3,5-bis(trifluoromethyl)acetophenone + NADPH + H+ <=> (R)-[3,5-bis(trifluoromethyl)phenyl]_ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
trans-2-hexenoyl-CoA + NADPH + CO2 + H+ <=> (S)-2-butylpropanedioyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
1-(2-bromophenyl)ethanol + NADP+ <=> 1-(2-bromophenyl)ethanone + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
phenylacylbromide + NADPH + H+ <=> 1-(2-bromophenyl)ethanone + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
4-aminoacetophenone + NADPH + H+ + O2 <=> 1-(4-aminophenyl)ethanol + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
3-quinuclidinone + NADPH + H+ <=> 1-azabicyclo[2.2.2]octan-3-ol + NADP+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
–
–
2,4-dichloro-1-nitrobenzene + 2 NADPH + 2 H+ <=> 2,4-dichloro-N-hydroxyaniline + 2 NADP+ + H2O 1.7.1.16 nitrobenzene nitroreductase
–
2-butylidene-cyclopentanone + NADPH + H+ <=> 2-butyl-cyclopentanone + NADP+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
–
2-chloro-1-phenylethan-1-ol + NADP+ <=> Chloroacetophenone + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
2-chloronitrobenzene + 2 NADPH + 2 H+ <=> 2-chloro-N-hydroxyaniline + 2 NADP+ + H2O 1.7.1.16 nitrobenzene nitroreductase
–
2-hetpylidene-cyclopentanone + NADPH + H+ <=> 2-heptylcyclopentanone + NADP+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
–
2-Pyrrolidone + NADPH + H+ <=> 2-hydroxypyrrolidine + NADP+ 1.1.1.206 tropinone reductase I
–
2-hydroxy-2-methyl-1-phenylpropan-1-one + NADPH + H+ <=> 2-methyl-1-phenylpropan-1,2-diol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
2-pentylidene-cyclopentanone + NADPH + H+ <=> 2-pentyl-cyclopentanone + NADP+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
–
2-acetylbenzonitrile + NADPH + H+ <=> 2-[(1S)-1-hydroxyethyl]benzonitrile + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
3-chloronitrobenzene + 2 NADPH + 2 H+ <=> 3-chloro-N-hydroxyaniline + 2 NADP+ + H2O 1.7.1.16 nitrobenzene nitroreductase
–
3-glutathionyl-hexanal + NADPH + H+ <=> 3-glutathionyl-hexan-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-glutathionyl-nonanal + NADPH + H+ <=> 3-glutathionyl-nonan-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-glutathionyl-propanal + NADPH + H+ <=> 3-glutathionyl-propan-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-hydroxydecanoyl-N-acetylcysteamine + NADP+ <=> 3-ketodecanoyl-N-acetylcysteamine + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
3-nitrotoluene + 2 NADPH + 2 H+ <=> N-hydroxy-3-methylaniline + 2 NADP+ + H2O 1.7.1.16 nitrobenzene nitroreductase
–
rac-1-nonen-4-ol + NADP+ <=> (S)-1-nonen-4-ol + 1-nonen-4-one + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
2-nonanone + NADPH + H+ + O2 <=> methyl_octanoate + NADP+ + H2O 1.14.13.226 acetone monooxygenase (methyl acetate-forming)
–
2,3,3-trimethyl-5-(trifluoromethyl)-3H-indole + NADH + H+ <=> (2R)-2,3,3-trimethyl-5-(trifluoromethyl)-2,3-dihydro-1H-indole + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
4,6-difluoro-2,3,3-trimethyl-3H-indole + NADPH + H+ <=> (2R)-4,6-difluoro-2,3,3-trimethyl-2,3-dihydro-1H-indole + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-(4-methylphenyl)-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-(4-methylphenyl)piperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
6-(prop-1-en-2-yl)-2,3,4,5-tetrahydropyridine + NADPH + H+ <=> (2S)-2-(prop-1-en-2-yl)piperidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
2-Hydroxy-1,4-naphthoquinone + 2 NADPH + H+ <=> (3S,4R)-3,4-dihydroxy-1-tetralone + 2 NADP+ 1.1.1.B57
–
3''-iodoacetophenone + NADPH + H+ <=> 1-(3''-iodophenyl)ethanol + NADP+ 1.1.1.B4
–
3''-trifluoromethylacetophenone + NADPH + H+ <=> 1-[(3''-trifluoromethyl)phenyl]ethanol + NADP+ 1.1.1.B4
–
1-(3-thienyl)acetone + NADPH + H+ <=> 1-(3-thienyl)ethanol + NADP+ 1.1.1.B4
–
2,3-dichloro-1,4-naphthoquinone + NADPH + H+ <=> 2,3-dichloro-1,4-naphthoquinol + NADP+ 1.6.5.5 NADPH:quinone reductase
–
5-chloro-L-kynurenine + NADPH + H+ + O2 <=> 5-chloro-3-hydroxy-L-kynurenine + NADP+ + H2O 1.14.13.9 kynurenine 3-monooxygenase
–
2,3-epoxy-1,4-naphthoquinone + NADPH + H+ <=> (1aS,7R,7aS)-7-hydroxy-7,7a-dihydronaphtho[2,3-b]oxiren-2(1aH)-one + NADP+ 1.1.1.B57
–
beta-carotene + NADPH + H+ + O2 <=> zeaxanthin + NADP+ + H2O 1.14.15.24 beta-carotene 3-hydroxylase
–
2,4,6-trihydroxybenzaldehyde + NADPH + H+ <=> 2,4-dihydroxy-6-oxocyclohex-1-ene-1-carbaldehyde + NADP+ 1.3.1.57 phloroglucinol reductase
–
Estradiol_sulfate + NADP+ <=> Estrone_3-sulfate + NADPH 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
2,6,6-trimethyl-4-oxocyclohex-2-ene-1-carbaldehyde + NADP+ <=> 2,2,6-trimethyl-4-oxocyclohexane-1-carbaldehyde + NADPH + H+ 1.3.1.82 (-)-isopiperitenone reductase
–
2,4,6-trihydroxy_acetophenone + NADPH + H+ <=> 2-acetyl-3,5-dihydroxycyclohex-2-en-1-one + NADP+ 1.3.1.57 phloroglucinol reductase
–
3,5,5-trimethyl-4-(propan-2-yl)cyclohex-2-en-1-one + NADP+ <=> 3,3,5-trimethyl-4-(propan-2-yl)cyclohexan-1-one + NADPH + H+ 1.3.1.82 (-)-isopiperitenone reductase
–
3,5-dimethylcyclohex-2-en-1-one + NADP+ <=> 3,5-dimethylcyclohexanone + NADPH + H+ 1.3.1.82 (-)-isopiperitenone reductase
–
4-androstene-3,17-dione + NADPH + H+ <=> 5alpha-Androstan-3,17-dione + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
3,8-divinyl_bacteriochlorophyllide_a + NADPH + H+ <=> bacteriochlorophyllide_a + NADP+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
methyl_2,4,6-trihydroxybenzoate + NADPH + H+ <=> methyl_2,4-dihydroxy-6-oxocyclohex-1-ene-1-carboxylate + NADP+ 1.3.1.57 phloroglucinol reductase
–
indole-3-acetic_acid + NADPH + O2 + H+ <=> 5-hydroxyindoleacetate + NADP+ + H2O 1.14.13.5 imidazoleacetate 4-monooxygenase
–
narcotine_hemiacetal + NADP+ <=> noscapine + NADPH + H+ 1.1.1.415 noscapine synthase
–
homoisocitrate + NADP+ <=> 2-oxoadipate + CO2 + NADPH + H+ 1.1.1.286 isocitrate---homoisocitrate dehydrogenase
–
ethyl_acetoacetate + NADPH <=> (S)-ethyl_3-hydroxybutyrate + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
–
–
–
–
methyl_acetoacetate + NADPH + H+ <=> (S)-methyl_3-hydroxybutyrate + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.283 methylglyoxal reductase (NADPH)
–
–
24-ethylidenelophenone + NADPH <=> 24-ethylidenelophenol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
3,4-dihydroxyphenylacetaldehyde + NADPH + H+ <=> 3,4-dihydroxyphenylethanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
tripolyphosphate + NAD+ <=> diphosphate + NADP+ 2.7.1.23 NAD+ kinase
–
5-Bromouracil + NADPH <=> 5-bromo-5,6-dihydrouracil + NADP+ 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
decanoyl-CoA + NADPH <=> decanal + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
trans-2-decenal + NADPH <=> decanal + NADP+ 1.3.1.27 2-hexadecenal reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
–
D-fructose + NADPH <=> sorbitol + NADP+ 1.1.1.123 sorbose 5-dehydrogenase (NADP+)
–
sorbitol + NADP+ <=> D-sorbose + NADPH 1.1.1.289 sorbose reductase
–
5beta-androstane-17beta-ol + NADP+ <=> 5alpha-androstane-17-one + NADPH 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
2-thio-FMN + NADPH + H+ <=> 2-thioFMNH2 + NADP+ 1.5.1.38 FMN reductase (NADPH)
–
peonidin + 2 NADPH + 2 H+ <=> (2S,3S)-3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-2,3-dihydro-1-benzopyran-1-ium + 2 NADP+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
–
arachidoyl-CoA + NADPH <=> eicosanal + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
ergosta-5,7,22-trien-3beta-ol + NADP+ <=> ergosta-5,7,22,24(241)-tetraen-3beta-ol + NADPH + H+ 1.3.1.71 Delta24(241)-sterol reductase
–
ethyl_3-oxovalerate + NADPH + H+ <=> ethyl_3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
indan-2-ol + NADP+ <=> 2-indanone + NADPH 1.1.1.112 indanol dehydrogenase
–
methyl_acetoacetate + NADPH + H+ <=> methyl-(R)-3-hydroxybutanoate + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
metyrapol + NADP+ <=> Metyrapone + NADPH + H+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
16-dehydroprogesterone + NADPH + O2 <=> 16,17-dehydro-21-hydroxyprogesterone + NADP+ + H2O 1.14.14.16 steroid 21-monooxygenase
–
oxidized_2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide + NADPH <=> reduced_2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide + NADP+ + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
trans-naphthalene_dihydrodiol + NADP+ <=> 1,2-naphthoquinone + NADPH 1.1.1.112 indanol dehydrogenase
–
tridecanal + NADP+ <=> tridecanoate + NADPH 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
squalene + NADH + O2 <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + NADP+ + H2O 1.14.14.17 squalene monooxygenase
–
2-trans,4-trans-decadienoyl-CoA + NADPH + H+ <=> (4E)-dec-4-enoyl-CoA + NADP+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
–
2,6-dibromophenol + NADPH + O2 <=> 2,6-dibromo-p-hydroquinone + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
2-Pentanone + NADP+ <=> 2-Pentanol + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
phenylpyruvate + methylamine + NADPH <=> N-methyl-L-phenylalanine + NADP+ + H2O 1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
–
(+)-limonene + NADPH + H+ + O2 <=> (+)-trans-carveol + NADP+ + H2O 1.14.14.53 (R)-limonene 6-monooxygenase
–
(+)-trans-carveol + NADP+ <=> (S)-carvone + NADPH + H+ 1.3.1.102 2-alkenal reductase (NADP+)
–
2-oxoisovalerate + NH3 + NADPH + H+ <=> D-valine + H2O + NADP+ 1.4.99.6 D-arginine dehydrogenase
–
L-galactose + NADP+ <=> L-galactonolactone + NADPH 1.1.1.B35
–
L-galactose + NADP+ <=> L-galactono-1,4-lactone + NADPH + H+ 1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.316 L-galactose 1-dehydrogenase
–
–
(+)-limonene + 2 O2 + 2 NADPH <=> (R)-cis-1,2-limonene_epoxide + (-)-cis-carveol + 2 NADP+ + 2 H2O 1.14.14.1 unspecific monooxygenase
–
(-)-cis-carveol + NADP+ <=> (-)-Carvone + NADPH + H+ 1.3.1.102 2-alkenal reductase (NADP+)
–
2,3-dihydromyricetin + NADPH <=> 3,4-cis-leucodelphinidin + NADP+ 1.1.1.219 dihydroflavonol 4-reductase
–
dihydrokaempferol + NADPH + H+ <=> leucopelargonidin + NADP+ 1.1.1.219 dihydroflavonol 4-reductase
–
D-Lysine + NADPH + H+ + O2 <=> N6-hydroxy-D-lysine + NADP+ + H2O 1.14.13.59 L-lysine N6-monooxygenase (NADPH)
–
24-methylidenecycloartanol + NADPH + O2 + H+ <=> (3beta,9beta)-24-methylidene-9,19-cyclolanostane-3,28-diol + NADP+ + H2O 1.14.18.10 plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase
–
21-Hydroxy-5beta-pregnane-3,20-dione + NADPH <=> 21-hydroxy-5beta-pregnane-20alpha-ol-3-one + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
ethyl_4-chloro-3-oxobutanoate + NADPH + H+ <=> (S)-4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
4-chloro-3-oxobutanoate + NADPH + H+ <=> (S)-4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.289 sorbose reductase
–
cyclohex-1-ene-1-carbonyl-CoA + NADPH + H+ <=> 2-cyclohexenylcarbonyl-CoA + NADP+ 1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+)
–
1alpha-hydroxycholecalciferol + O2 + NADPH + H+ <=> 1alpha,25-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
–
vitamin_D3 + O2 + NADPH + H+ <=> 1alpha,25-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
–
1,2-benzoquinone + NADPH + H+ <=> catechol + NADP+ 1.14.13.31 2-nitrophenol 2-monooxygenase
–
trans-2-dodecenal + NADPH <=> dodecanal + NADP+ 1.3.1.27 2-hexadecenal reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
–
lauroyl-CoA + NADPH <=> dodecanal + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
nitroblue_tetrazolium + 2 NADPH <=> Nitroblue_tetrazolium_formazan + 2 NADP+ 1.14.13.39 nitric-oxide synthase (NADPH)
–
palmitoyl-CoA + NADPH <=> hexadecanal + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
2-cis-hexadecenal + NADPH + H+ <=> hexadecanal + NADP+ 1.3.1.27 2-hexadecenal reductase
–
(-)-menthone + NADPH <=> (1R)-menthole + NADP+ 1.1.1.207 (-)-menthol dehydrogenase
–
2-halo-acetophenone + NADPH <=> (R)-2-halo-1-phenylethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
(E)-4-hydroxy-3-methylbut-2-en-1-yl_diphosphate + NADPH + H+ <=> dimethylallyl_diphosphate + NADP+ + H2O 1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase
–
prostaglandin_H2 + NADPH <=> Prostaglandin_D2 + NADP+ 1.1.1.188 prostaglandin-F synthase
–
Prostaglandin_D2 + NADP+ <=> 9alpha,11beta-prostaglandin_F2 + NADPH 1.1.1.188 prostaglandin-F synthase
–
benzocyclobutanone + NADPH + H+ + O2 <=> coumaranone + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
2'',4''-difluoro-acetophenone + NADPH + H+ <=> 1-(2'',4''-difluoro)-phenylethanol + NADP+ 1.1.1.B4
–
germanicol + 3 O2 + 3 NADPH + 3 H+ <=> morolate + 3 NADP+ + 4 H2O 1.14.14.126 beta-amyrin 28-monooxygenase
–
2-deoxy-D-galactose + NADP+ <=> D-galactono-1,5-lactone + NADPH 1.1.1.120 galactose 1-dehydrogenase (NADP+)
–
2-deoxy-D-galactose + NADP+ <=> 2-Deoxy-D-galactono-1,5-lactone + NADPH 1.1.1.48 D-galactose 1-dehydrogenase
–
2 5alpha-dihydrotestosterone + 2 NADPH + 2 H+ <=> 5alpha-Androstane-3beta,17beta-diol + 5alpha-androstane-3alpha,17beta-diol + 2 NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
(2Z)-2-(5-hydroxy-4,6-dimethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-N,N-di(prop-2-en-1-yl)hydrazinecarbothioamide + NADPH+_H+ <=> 5alpha-androstane-3alpha,17beta-diol + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
D-talose + NADP+ <=> D-talono-1,4-lactone + NADPH + H+ 1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
–
4-desmethyllanosterol + NADP+ <=> 4-desmethyllanosterone + NADPH + CO2 + H+ 1.1.1.417 3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating)
–
8-nitroxanthine + NADPH <=> 8-aminoxanthine + NADP+ + H2O 1.8.1.4 dihydrolipoyl dehydrogenase
–
iso18:1-O-alkylglycerol-bis-trimethylsilyl_ether + NADPH + O2 <=> iso18:1-dimethylacetal + NADP+ + H2O 1.14.19.77 plasmanylethanolamine desaturase
–
iso18:0-O-alkylglycerol-bis-trimethylsilyl_ether + NADPH + O2 <=> iso18:0-dimethylacetal + NADP+ + H2O 1.14.19.77 plasmanylethanolamine desaturase
–
iso16:0-O-alkylglycerol-bis-trimethylsilyl_ether + NADPH + O2 <=> iso16:0-dimethylacetal + NADP+ + H2O 1.14.19.77 plasmanylethanolamine desaturase
–
iso15:0-O-alkylglycerol-bis-trimethylsilyl_ether + NADPH + O2 <=> iso15:0-dimethylacetal + NADP+ + H2O 1.14.19.77 plasmanylethanolamine desaturase
–
pterin + NADPH <=> pterin + NADP+ 1.5.1.3 dihydrofolate reductase
–
S-(2-aminoethyl)-L-cysteine + NADP+ + H2O <=> S-(2-oxoethyl)-L-cysteine + NADPH + NH3 1.4.1.15 lysine dehydrogenase
–
germacra-1(10),4,11(13)-trien-12-oate + NADPH + H+ + O2 <=> (+)-costunolide + NADP+ + 2 H2O 1.14.13.120 costunolide synthase
–
4alpha-methylfecosterone + NADPH + H+ <=> 4alpha-methylfecosterol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
o-vanillin + NADPH + H+ <=> 2-hydroxy-3-methoxybenzyl_alcohol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
pyruvate + NH3 + NADPH + H+ <=> D-alanine + NADP+ 1.4.1.16 diaminopimelate dehydrogenase
–
5beta-dihydrotestosterone + NADP+ <=> 5beta-17-oxo-dihydrotestosterone + NADH 1.1.1.112 indanol dehydrogenase
–
5beta-dihydrotestosterone + NADP+ <=> 5beta-17-oxo-dihydrotestosterone + NADPH 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
4-chloro-3-oxobutanoate + NADPH + H+ <=> ethyl_(S)-4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
ethyl_acetoacetate + NADPH <=> ethyl_(R)-3-hydroxybutanoate + NADP+ 1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase
–
2-Hydroxy-1,4-naphthoquinone + NADPH <=> 2-hydroxy-1,4-naphthoquinol + NADP+ 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
–
cyclohex-1,4-diene-1-carboxyl-CoA + NADP+ <=> DELTA3-cyclohexenecarboxyl-CoA + NADPH + H+ 1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+)
–
cyclohexa-1,3-diene-1-carbonyl-CoA + NADP+ <=> DELTA3-cyclohexenecarboxyl-CoA + NADPH + H+ 1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+)
–
alkyl_ether_plasmanylethanolamine + NADPH + O2 <=> vinyl_ether_phosphatidylethanolamine + NADP+ + H2O 1.14.19.77 plasmanylethanolamine desaturase
–
3-hydroxybenzoate + NADPH + O2 <=> 2,5-Dihydroxybenzoate + NADP+ + H2O 1.14.13.24 3-hydroxybenzoate 6-monooxygenase
–
B
5alpha-Cholest-7-en-3beta-ol + NADPH + H+ <=> 7-oxocholestanol + cholestanol-7alpha,8alpha-epoxide + NADP+ + H2O 1.14.14.23 cholesterol 7alpha-monooxygenase
–
5beta-pregnan-20alpha-ol-3-one + NADPH <=> 5beta-pregnane-3,20-dione + NADP+ 1.1.1.62 17beta-estradiol 17-dehydrogenase
–
protochlorophyllide + O2 + NADPH <=> 7-hydroxychlorophyllide_a + H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
ergosta-5,7-dien-3beta-ol + NADPH + H+ + O2 <=> ergosterol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
ergosta-5,7-dienol + NADPH + H+ + O2 <=> ergosterol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
2,6-dibromo-4-nitrophenol + NADPH + O2 <=> 2,6-dibromo-p-hydroquinone + nitrite + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
4-nitrocatechol + NADPH + H+ + O2 <=> Hydroxyquinol + nitrite + NADP+ + H2O 1.14.13.166 4-nitrocatechol 4-monooxygenase
–
3-Methyl-4-nitrophenol + O2 + NADPH + H+ <=> methyl-1,4-benzoquinone + nitrite + H2O + NADP+ 1.14.13.167 4-nitrophenol 4-monooxygenase
1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
–
–
2-chloro-4-nitrophenol + NADPH + H+ + O2 <=> 2-chloro-1,4-benzoquinone + nitrite + NADP+ + H2O 1.14.13.167 4-nitrophenol 4-monooxygenase
–
4-Methyl-2-nitrophenol + NADPH + H+ + O2 <=> 4-methylcatechol + NADP+ + H2O + nitrite 1.14.13.31 2-nitrophenol 2-monooxygenase
–
2-Nitrophenol + NADPH + H+ + O2 <=> 1,2-benzoquinone + NADP+ + H2O + nitrite 1.14.13.31 2-nitrophenol 2-monooxygenase
–
5-fluoro-2-nitrophenol + NADPH + H+ + O2 <=> 4-Fluorocatechol + NADP+ + H2O + nitrite 1.14.13.31 2-nitrophenol 2-monooxygenase
–
trans-2-nonenal + NADPH <=> Nonanal + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
1.3.1.27 2-hexadecenal reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
–
–
–
–
2-nonenal + NADPH + H+ <=> Nonanal + NADP+ 1.3.1.27 2-hexadecenal reductase
1.6.5.5 NADPH:quinone reductase
–
–
1-octen-3-one + NADPH + H+ <=> Nonanal + NADP+ 1.3.1.27 2-hexadecenal reductase
–
peroxynitrite + NADPH <=> nitrite + H2O + NADP+ 1.8.1.7 glutathione-disulfide reductase
–
menadione + NADH <=> menadiol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
NADPH + H+ + oxidized_menadione <=> NADP+ + menadiol 1.6.2.4 NADPH---hemoprotein reductase
–
1,3-butanediol + NADP+ <=> 3-hydroxybutanal + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-deoxy-D-glucose_6-phosphate + NADP+ <=> 2-deoxy-D-glucono-1,5-lactone_6-phosphate + NADPH 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
–
2-deoxy-D-glucose_6-phosphate + NADP+ <=> 2-deoxy-6-phosphono-D-gluconate + NADPH 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
2,3,5,6-tetrafluorophenol + O2 + NADPH <=> 3,4,6-trifluoro-2-benzoquinone + NADP+ + F- 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
4-Chlorobenzaldehyde + NADP+ + H2O <=> 4-Chlorobenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
Epitestosterone + NADP+ <=> testosterone + NADPH + H+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
diacetyl + NADPH <=> 4-hydroxy-2-butanone + NADP+ 1.1.1.263 1,5-anhydro-D-fructose reductase
–
N-Methylanthranilate + NADPH + O2 <=> 2,3-Dihydroxybenzoate + NADP+ + NH3 1.14.13.35 anthranilate 3-monooxygenase (deaminating)
–
L-Dopa + NADPH <=> 3,4-Dihydroxyphenylpropionate + NADP+ + NH3 4.3.1.22 3,4-dihydroxyphenylalanine reductive deaminase
–
4-fluoroanthranilate + NADPH + O2 <=> 4-fluoro-2,3-dihydroxybenzoate + NADP+ + NH3 1.14.13.35 anthranilate 3-monooxygenase (deaminating)
–
5-fluoroanthranilate + NADPH + O2 <=> 5-fluoro-2,3-dihydroxybenzoate + NADP+ + NH3 1.14.13.35 anthranilate 3-monooxygenase (deaminating)
–
S-nitrosoglutathione + NADPH + H+ <=> GSSG + hydroxylamine + NH3 + NADP+ 1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase
–
sulindac_sulfide + NADPH + O2 <=> sulindac + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
CO + H2O + NADP+ <=> CO2 + NADPH + H+ 1.2.7.4 anaerobic carbon monoxide dehydrogenase
–
(2E,6Z)-nonadienal + NADP+ <=> trans-2,cis-6-nonadienol + NADPH 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
beta-ketobutyryl-CoA + NADPH <=> 3-hydroxybutyryl-CoA + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
primary_fluorescent_chlorophyll_catabolite + NADP+ <=> red_chlorophyll_catabolite + NADPH + H+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
1.3.7.12 red chlorophyll catabolite reductase
–
–
Chlorate + NADPH <=> Chlorite + NADP+ 1.7.1.3 nitrate reductase (NADPH)
–
3-methylbut-2-enal + NADPH <=> Isovaleraldehyde + NADP+ 1.3.1.31 2-enoate reductase
–
NADPH + O2 <=> NADP+ + O2- 1.17.1.4 xanthine dehydrogenase
1.6.2.4 NADPH---hemoprotein reductase
1.6.3.1 NAD(P)H oxidase (H2O2-forming)
–
–
–
prostaglandin_F2alpha + NADP+ <=> 15-ketoprostaglandin_F2alpha + NADH + H+ 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+)
–
prostaglandin_F2alpha + NADP+ <=> prostaglandin_E1 + NADPH 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
–
prostaglandin_F2alpha + NADP+ <=> prostaglandin_F2alpha + Prostaglandin_B2 + NADPH 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
prostaglandin_F2alpha + NADP+ <=> 15-ketoprostaglandin_F2alpha + NADPH + H+ 1.1.1.189 prostaglandin-E2 9-reductase
1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
–
–
–
B
(S)-phospholactate + NADPH + H+ <=> sphinganine + L(-)threo-Sphinganine + NADP+ 1.1.1.102 3-dehydrosphinganine reductase
–
(S)-phospholactate + NADPH + H+ <=> sphinganine + NADP+ 1.1.1.102 3-dehydrosphinganine reductase
–
2-amino-1-hydroxyoctadecan-3-one + NADPH <=> sphinganine + NADP+ 1.1.1.102 3-dehydrosphinganine reductase
–
Styrene + NADPH + O2 <=> styrene_oxide + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
1.14.13.B28
–
–
delphinidin + NADPH <=> epigallocatechin + (-)-gallocatechin + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
methyl_farnesoate + NADPH + H+ + O2 <=> juvenile_hormone_III + NADP+ + H2O 1.14.13.202 methyl farnesoate epoxidase
–
2-Methylpropane + NADH + O2 <=> isobutanol + tert-butanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
2-Methylpropane + NADPH + O2 <=> isobutanol + tert-butanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
methyl_tert-butyl_ether + NADPH + H+ + O2 <=> tert-butanol + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
2-acetolactate + NADP+ <=> (R)-2,3-dihydroxy-3-methylbutanoate + NADPH + H+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
[(E)-1-methyl-2-nitroethenyl]benzene + NADP+ <=> [(2S)-2-methyl-3-nitropropyl]benzene + NADPH + H+ 1.3.1.31 2-enoate reductase
1.6.99.1 NADPH dehydrogenase
–
–
[(E)-1-methyl-2-nitroethenyl]benzene + NADP+ <=> [(1R)-1-methyl-2-nitroethyl]benzene + NADPH + H+ 1.3.1.31 2-enoate reductase
–
[(E)-1-methyl-2-nitroethenyl]benzene + NADP+ <=> [(1S)-1-methyl-2-nitroethyl]benzene + NADPH + H+ 1.3.1.31 2-enoate reductase
–
nerol + NADP+ <=> citral + NADPH + H+ 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.90 aryl-alcohol dehydrogenase
–
–
nerol + NADP+ <=> neral + citral + NADPH 1.1.1.183 geraniol dehydrogenase (NADP+)
–
palmitoyl-CoA + NADPH + O2 <=> palmitoleic_acid + NADP+ + H2O 1.14.19.1 stearoyl-CoA 9-desaturase
–
(R)-3-hydroxybutyryl-CoA + NADPH + H+ <=> acetoacetyl-CoA + NADP+ 1.1.1.36 acetoacetyl-CoA reductase
–
B
Pyridine-3-aldehyde + NADP+ <=> 3-Pyridylcarbinol + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
2-trans,4-trans-decadienoyl-CoA + NADPH <=> trans-2-decenoyl-CoA + NADP+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
alpha-amyrin + 3 O2 + 3 NADPH + 3 H+ <=> ursolic_acid + 3 NADP+ + 4 H2O 1.14.14.126 beta-amyrin 28-monooxygenase
–
(5R,S)-albaflavenol + NADPH + H+ + O2 <=> albaflavenone + NADP+ + H2O 1.14.13.106 epi-isozizaene 5-monooxygenase
–
dimethyl_(2E)-2-methylbut-2-enedioate + NADPH <=> dimethyl_(2R)-2-methylbutanedioate + dimethyl_(2S)-2-methylbutanedioate + NADP+ 1.3.1.31 2-enoate reductase
–
dimethyl_(2Z)-2-methylbut-2-enedioate + NADPH <=> dimethyl_(2R)-2-methylbutanedioate + NADP+ 1.3.1.31 2-enoate reductase
–
dimethyl_2-methylidenebutanedioate + NADPH <=> dimethyl_(2R)-2-methylbutanedioate + NADP+ 1.3.1.31 2-enoate reductase
–
NADPH + hydroxylamine <=> NADP+ + NH3 + H2O 1.7.1.10 hydroxylamine reductase (NADH)
1.7.1.4 nitrite reductase [NAD(P)H]
1.8.1.2 assimilatory sulfite reductase (NADPH)
–
–
–
L-valine + O2 + NADPH + H+ <=> Isobutyraldoxime + NADP+ + CO2 + H2O 1.14.14.38 valine N-monooxygenase
–
L-isoleucine + O2 + NADPH + H+ <=> (Z)-2-methylbutanal_oxime + NADP+ + CO2 + H2O 1.14.14.38 valine N-monooxygenase
–
chloroform + NADPH + O2 <=> CO2 + Cl- + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
4-hydroxybenzoate + 2 NADPH + 2 I- + 2 O2 + 2 H+ <=> 2,4-diiodophenol + 2 NADP+ + CO2 + 4 H2O 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
salicylate + O2 + NADPH + 2 H+ <=> catechol + CO2 + H2O + NADP+ 1.14.13.1 salicylate 1-monooxygenase
–
anthranilate + NADPH + O2 <=> 2-Aminophenol + NADP+ + H2O2 + CO2 1.14.13.27 4-aminobenzoate 1-monooxygenase
–
4-aminosalicylic_acid + NADPH + O2 <=> 4-Aminocatechol + NADP+ + H2O2 + CO2 1.14.13.27 4-aminobenzoate 1-monooxygenase
–
4-hydroxybenzoate + NADPH + O2 <=> hydroquinone + NADP+ + H2O2 + CO2 1.14.13.27 4-aminobenzoate 1-monooxygenase
–
3,4-Diaminobenzoate + NADPH + O2 <=> 2-amino-4-hydroxyaniline + NADP+ + H2O2 + CO2 1.14.13.27 4-aminobenzoate 1-monooxygenase
–
4-Amino-2-chlorobenzoate + NADPH + O2 <=> 3-chloro-4-hydroxyaniline + NADP+ + H2O2 + CO2 1.14.13.27 4-aminobenzoate 1-monooxygenase
–
2-Amino-5-chlorobenzoate + NADPH + O2 <=> 2-amino-5-chlorophenol + NADP+ + H2O2 + CO2 1.14.13.27 4-aminobenzoate 1-monooxygenase
–
2,4-Dihydroxybenzoate + NADPH + O2 <=> Hydroxyquinol + CO2 + H2O + NADP+ 1.14.13.1 salicylate 1-monooxygenase
1.14.13.64 4-hydroxybenzoate 1-hydroxylase
–
–
2-Fluoro-4-hydroxybenzoate + NADPH + O2 <=> 2-fluoro-1,4-dihydroxybenzene + NADP+ + CO2 1.14.13.64 4-hydroxybenzoate 1-hydroxylase
–
Tartrate + NADPH <=> D-glycerate + NADP+ + CO2 1.1.1.92 oxaloglycolate reductase (decarboxylating)
–
phenylpyruvate + NADPH + H+ + O2 <=> phenylacetate + NADP+ + H2O + CO2 1.14.13.168 indole-3-pyruvate monooxygenase
–
4-Hydroxy-3-nitrobenzoate + NADPH + O2 <=> 4-hydroxy-2-nitrophenol + NADP+ + CO2 1.14.13.64 4-hydroxybenzoate 1-hydroxylase
–
8-O-methylsterigmatocystin + reduced_flavodoxin + O2 <=> aflatoxin_B1 + 2 NADP+ + methanol + flavin + H2O + CO2 1.14.14.117 aflatoxin B synthase
–
2,3,5,6-Tetrafluoro-4-hydroxybenzoate + NADPH + O2 <=> 2,3,5,6-tetrafluorohydroquinone + NADP+ + CO2 1.14.13.64 4-hydroxybenzoate 1-hydroxylase
–
2,4-Dihydroxybenzoate + 2 NADPH + 2 Br- + 2 O2 + 2 H+ <=> 3,5-dibromobenzene-1,2-diol + 4-bromocatechol + 2 NADP+ + CO2 + 4 H2O 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
3,4-dihydroxybenzoate + 2 NADPH + 2 Br- + 2 O2 + 2 H+ <=> 3,5-dibromobenzene-1,2-diol + 4-bromocatechol + 2 NADP+ + CO2 + 4 H2O 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
oxytetracycline + reduced_flavodoxin + NADPH + O2 <=> 11a-hydroxy-oxytetracycline + flavin + H2O + NADP+ 1.14.13.231 tetracycline 11a-monooxygenase
–
(S)-pulegone + NADPH + H+ <=> (1S,4S)-isomenthone + (1S,4R)-menthone + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
–
prostamide_H2 + NADPH + H+ <=> prostamide_F2alpha + NADP+ 1.1.1.188 prostaglandin-F synthase
–
4''-methoxyacetophenone + NADPH + H+ <=> 1-(4-methoxyphenyl)ethanol + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
erythritol + NADP+ <=> L-erythrose + NADPH 1.1.1.287 D-arabinitol dehydrogenase (NADP+)
–
vinyl_alcohol + NADP+ <=> polyvinylketone + H2O2 1.1.3.18 secondary-alcohol oxidase
–
all-trans-retinal + NADPH <=> NADP+ + H2O + retinoic_acid 1.2.1.36 retinal dehydrogenase
–
folate + NADPH + H+ <=> 7,8-dihydrofolate + tetrahydrofolate + NADP+ 1.5.1.33 pteridine reductase
–
2-naphthaldehyde + NADP+ + H2O <=> 2-naphthoic_acid + NADPH + H+ 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
–
5alpha-androstane-3,17-dione + NADPH + H+ <=> 5alpha-Androstan-3alpha-ol-17-one + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
5alpha-Androstan-3,17-dione + NADPH <=> 5alpha-Androstan-3alpha-ol-17-one + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
divinyl_chlorophyllide_a + reduced_ferredoxin_[iron-sulfur]_cluster + NADPH + H+ <=> chlorophyllide_a + oxidized_ferredoxin + NADP+ 1.3.7.13 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin)
–
farnesol + NADP+ <=> (2E,6E)-farnesal + NADPH 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.216 farnesol dehydrogenase (NADP+)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
farnesol + NADP+ <=> cis,trans-farnesal + NADPH 1.1.1.216 farnesol dehydrogenase (NADP+)
–
20alpha-hydroxyprogesterone + NADP+ <=> 4-pregnen-3alpha,20beta-diol + NADPH 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
Pro-Thr-Val-Thr-Gly-Cys-S-S-Cys-Gly + NADPH + H+ <=> Pro-Thr-Val-Thr-Gly-Cys + Cys-Gly + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
2-Cyclohexen-1-ol + NADPH <=> 2-cyclohexen-1-one + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
1,2-Butanediol + NADP+ <=> 1-hydroxy-2-butanone + NADPH 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
–
1,2-Butanediol + NADP+ <=> 2-hydroxybutyraldehyde + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
–
4-hydroxy-3-nitrobenzaldehyde + NADPH + O2 <=> 3,4-Dihydroxybenzaldehyde + NADP+ + H2O 1.14.13.31 2-nitrophenol 2-monooxygenase
–
3-Chlorobenzaldehyde + NADP+ + H2O <=> 3-chlorobenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
CO + NADH + H+ + H2O <=> CO2 + NADP+ 1.2.5.3 aerobic carbon monoxide dehydrogenase
–
CO + NADPH + O2 <=> CO2 + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
2,5-diamino-6-(1-D-ribosylamino)-4(3H)-pyrimidinone_5''-phosphate + NADPH + H+ <=> 2,5-diamino-6-(1-D-ribitylamino)-4(3H)-pyrimidinone_5''-phosphate + NADP+ 1.1.1.302 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
–
3-phospho-D-glycerate + NADP+ <=> 3-phosphohydroxypyruvate + NADPH + H+ 1.1.1.95 phosphoglycerate dehydrogenase
–
D-glyceraldehyde_3-phosphate + NADP+ + H2O <=> 3-phospho-D-glycerate + NADP+ + H+ 1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
–
eriodictyol + NADP+ <=> luteoforol + NADPH + H+ 1.1.1.234 flavanone 4-reductase
–
5,10-methylenetetrahydrofolate + uracil54_in_tRNA + NADPH + H+ <=> tetrahydrofolate + 5-methyluracil54_in_tRNA + NADP+ 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]
–
4-methyl-2-pentanone + NADPH + H+ <=> 4-methyl-2-pentanol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
7,8-dihydrofolate + NADP+ + H+ <=> tetrahydrofolate + NADP+ 1.5.1.3 dihydrofolate reductase
–
3-Nitrobenzaldehyde + NADP+ + H2O <=> 3-Nitrobenzoate + NADPH + 2 H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
2-methoxy-1,4-benzoquinone + NADPH <=> 4-methoxyphenol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
D-galactose_6-phosphate + NADP+ <=> 6-phospho-D-galactonate + NADH 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
L-methionine_sulfoxide_enkephalin + NADPH <=> Met-enkephalin + NADP+ + H2O 1.8.4.13 L-methionine (S)-S-oxide reductase
–
NADPH + nitroblue_tetrazolium + H2O <=> NADP+ + nitroblue_tetrazolium 1.17.1.4 xanthine dehydrogenase
–
CTP + NAD+ <=> CDP + NADP+ 2.7.1.23 NAD+ kinase
–
NADPH + oxidized_acetylpyridine_adenine_dinucleotide + H+ <=> NADP+ + reduced_acetylpyridine_adenine_dinucleotide + H+ 7.1.1.1 proton-translocating NAD(P)+ transhydrogenase
–
NADPH + 3-acetylpyridine_adenine_dinucleotide <=> NADP+ + reduced_acetylpyridine_adenine_dinucleotide 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)
7.1.1.1 proton-translocating NAD(P)+ transhydrogenase
–
–
–
NADPH + ocidized_3-acetylpyridine_adenine_dinucleotide + H+ <=> NADP+ + reduced_acetylpyridine_adenine_dinucleotide + H+ 7.1.1.1 proton-translocating NAD(P)+ transhydrogenase
–
NADPH + deamido-NAD+ + H+ <=> NADP+ + reduced_acetylpyridine_adenine_dinucleotide + H+ 7.1.1.1 proton-translocating NAD(P)+ transhydrogenase
–
(R)-4-dehydropantoate + NADPH + H+ <=> (R)-pantoate + NADP+ 1.1.1.169 2-dehydropantoate 2-reductase
–
heptane + NADPH + O2 <=> 1-Heptanol + 2-Heptanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
D-mannose + NADP+ <=> D-mannono-1,5-lactone + NADPH 1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.121 aldose 1-dehydrogenase (NAD+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
–
–
–
2-dehydro-D-glucose + NADPH + H+ <=> D-mannose + NADP+ 1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
–
beta-D-fucose + NADP+ <=> D-galactono-1,5-lactone + NADPH 1.1.1.120 galactose 1-dehydrogenase (NADP+)
–
3,8-divinyl_chlorophyll_a + NADPH + H+ <=> chlorophyll_a + NADP+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
D-altrose + NADP+ <=> D-altrono-1,5-lactone + NADPH 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
D-allosone + NADPH + H+ <=> D-altrose + NADP+ 1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
–
D-fructose_6-phosphate + NADPH + H+ <=> D-mannitol_1-phosphate + NADP+ 1.1.1.17 mannitol-1-phosphate 5-dehydrogenase
–
6-pyruvoyltetrahydropterin + 3 NADPH + 3 H+ <=> L-threo-7,8-dihydrobiopterin + 3 NADP+ 1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
–
lithocholic_acid + NADPH + H+ <=> ursodeoxycholate + NADP+ 1.1.1.159 7alpha-hydroxysteroid dehydrogenase
1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
–
chenodeoxycholic_acid + NADPH + H+ <=> ursodeoxycholate + NADP+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
2,3-bis-O-phytyl-sn-glyceryl_phosphate + NADPH + H+ <=> 2,3-bis-O-phytanyl-sn-glycerol_1-phosphate + NADP+ 1.3.1.101 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]
–
1-Acenaphthenol + NADP+ <=> acenaphthylen-1-ol + NADPH 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
D-fructose + NADPH <=> 5-dehydro-D-fructose + NADP+ 1.1.1.69 gluconate 5-dehydrogenase
–
(9R,13R)-12-oxophytodienoate + NADPH <=> 3-oxo-2-(2'-[Z]-pentenyl)cyclopentane-1-hexanoic_acid + NADP+ 1.3.1.42 12-oxophytodienoate reductase
–
cyclopentane + NADPH + H+ + O2 <=> Cyclopentanol + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
Cyclopentanone + NADPH <=> Cyclopentanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Cyclopentanol + NADP+ <=> cyclopentanal + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-butanone + NADPH + H+ + O2 <=> ethyl_acetate + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
(+)-cis-3,4-dihydrophenanthrene-3,4-diol + NADP+ <=> 3,4-Dihydroxyphenanthrene + NADPH + H+ 1.3.1.49 cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
–
Naphthalene + NADPH + O2 <=> (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NADP+ 1.14.12.12 naphthalene 1,2-dioxygenase
1.14.12.18 biphenyl 2,3-dioxygenase
1.14.12.22 carbazole 1,9a-dioxygenase
–
–
–
1-Acenaphthenol + NADP+ <=> 1-Acenaphthenone + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
2-methylcyclohexanone + NADPH + O2 <=> 1-Oxa-2-oxo-3-methylcycloheptane + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
16alpha-Methylcortisol + NADP+ <=> 16alpha-Methylcortisone + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
genistein + NADPH + H+ + O2 <=> 2''-hydroxygenistein + NADP+ + H2O 1.14.13.53 4'-methoxyisoflavone 2'-hydroxylase
1.14.13.89 isoflavone 2'-hydroxylase
–
–
1-hydroxylamino-3-nitrobenzene + 2 NADPH + 2 H+ <=> 3-nitroaniline + 2 NADP+ + H2O 1.7.1.16 nitrobenzene nitroreductase
–
1,3-dinitrobenzene + 2 NADPH + 2 H+ <=> 3-nitroaniline + 2 NADP+ + H2O 1.7.1.16 nitrobenzene nitroreductase
–
2-trans,4-cis-decadienoyl-CoA + NADPH <=> trans-3-decenoyl-CoA + NADP+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
–
2-sulfoacetaldehyde + H2O + NADP+ <=> Sulfoacetate + NADH + H+ 1.2.1.73 sulfoacetaldehyde dehydrogenase
–
2-sulfoacetaldehyde + H2O + NADP+ <=> Sulfoacetate + NADPH + H+ 1.2.1.73 sulfoacetaldehyde dehydrogenase
–
3alpha,7beta-dihydroxy-5beta-cholanoyl_glycine + NADP+ <=> 3alpha-Hydroxy-7-keto-5beta-cholanoyl_glycine + NADPH 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
3alpha,7beta-dihydroxy-5beta-cholanoyl_taurine + NADP+ <=> 2[[3alpha-hydroxy-7,24-dioxo-5beta-cholan-24-yl]amino]ethane_sulfonic_acid + NADPH 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
4-methoxycinnamyl_alcohol + NADP+ <=> 4-methoxycinnamaldehyde + NADPH 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
imidazoleacetate + NADPH + O2 + H+ <=> 5-hydroxy-4-imidazoleacetate + NADP+ + H2O 1.14.13.5 imidazoleacetate 4-monooxygenase
–
5beta-androstane-3,17-dione + NADPH <=> 5beta-Androstan-3alpha,17alpha-diol + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
5beta-Androstan-3alpha-ol-17-one + NADPH <=> 5beta-Androstan-3alpha,17alpha-diol + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
7alpha-Hydroxy-4-cholesten + NADPH <=> 7alpha-hydroxy-5beta-cholestan-3-one + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
(S)-N-methylcanadine + NADPH + H+ + O2 <=> Allocryptopine + NADP+ + H2O 1.14.14.97 methyltetrahydroprotoberberine 14-monooxygenase
–
3-dehydro-alpha-ecdysone + NADPH + H+ <=> alpha-ecdysone + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
17alpha-hydroxypregnenolone + NADP+ <=> 17alpha-hydroxy-pregn-5-en-3,20-dione + NADPH 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
chlorpromazine + NADPH + O2 <=> Chlorpromazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
cis-11-hexadecenal + NADPH <=> cis-11-Hexadecenol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
trans-trans-2,4-hexadienoyl-CoA + NADPH + H+ <=> 3-trans-hexenoyl-CoA + NADP+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
Toluene + NADPH + O2 <=> Cresol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
cholestanol + O2 + NADPH + H+ <=> 5alpha-Cholest-7-en-3beta-ol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
D-glucuronolactone + NADPH <=> D-gulono-1,4-lactone + NADP+ 1.1.1.20 glucuronolactone reductase
–
arachidoyl-CoA + NADP+ <=> eicosanal + CoA + NADPH 1.2.1.50 long-chain acyl-protein thioester reductase
–
Estrone_3-sulfate + NADPH <=> estradiol_3-sulfate + NADP+ 1.1.1.62 17beta-estradiol 17-dehydrogenase
–
Geissoschizine + NADP+ <=> 4,21-didehydrogeissoschizine + NADPH 1.3.1.36 geissoschizine dehydrogenase
–
nortropine + NADP+ <=> Nortropinone + NADPH 1.1.1.206 tropinone reductase I
–
Lumiflavin + NADPH + H+ <=> reduced_lumiflavin + NADP+ 1.5.1.30 flavin reductase (NADPH)
–
1-phenyl-1,2-propanedione + NADPH + H+ <=> (S)-2-Hydroxypropiophenone + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3,4-Dihydroxyphenylacetate + NADPH + O2 + H+ <=> 2,4,5-Trihydroxyphenylacetate + NADP+ + H2O 1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase
–
25-hydroxycholesterol + NADPH + H+ + O2 <=> 7alpha,25-Dihydroxycholesterol + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
27-Hydroxycholesterol + NADPH + H+ + O2 <=> 7alpha,27-dihydroxycholesterol + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
17alpha-hydroxyprogesterone + NADPH + O2 <=> 11-deoxycortisol + NADP+ + H2O 1.14.14.16 steroid 21-monooxygenase
–
17-hydroxy-pregn-4-ene-3,20,21-trione + NADPH <=> 11-deoxycortisol + NADP+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
d-isomenthone + NADPH <=> d-neoisomenthol + NADP+ 1.1.1.207 (-)-menthol dehydrogenase
–
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ <=> 21-hydroxy-pregn-4-en-3,11,20-trione + NADPH + H+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
Urate + NADPH + H+ + O2 <=> 5-hydroxyisourate + NADP+ + H2O 1.14.13.113 FAD-dependent urate hydroxylase
–
xanthine + NADP+ + H2O <=> Urate + NADPH 1.17.1.4 xanthine dehydrogenase
–
DL-diaminopimelic_acid + H2O + NADP+ <=> 2-Amino-6-oxoheptanedioate + NH3 + NADPH 1.4.1.16 diaminopimelate dehydrogenase
–
1,4-benzoquinone + NADPH + H+ <=> 1,4-benzosemiquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
–
–
1,2-dihydro-beta-NADPH + H+ + O2 <=> NADP+ + H2O2 1.6.3.5 renalase
–
1,6-dihydro-beta-NADPH + H+ + O2 <=> NADP+ + H2O2 1.6.3.5 renalase
–
4-carboxybenzaldehyde + NADP+ + H2O <=> terephthalate + NADPH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
–
–
5beta-androstane-3,17-dione + NADPH <=> 5beta-Androstan-3alpha-ol-17-one + NADP+ 1.1.1.188 prostaglandin-F synthase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
benzoylformate + NADPH + H+ <=> Mandelate + NADP+ 1.1.1.1 alcohol dehydrogenase
–
menadione + NADPH <=> menadione + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
beta-amyrin + 3 O2 + 3 NADPH + 3 H+ <=> oleanolic_acid + 3 NADP+ + 4 H2O 1.14.14.126 beta-amyrin 28-monooxygenase
–
DL-threitol + NADP+ <=> D-erythrulose + NADPH 1.1.1.10 L-xylulose reductase
–
2-butanone + NADPH + H+ + O2 <=> methyl_propionate + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
1.14.13.226 acetone monooxygenase (methyl acetate-forming)
–
–
taxifolin + NADPH <=> (2R,3S,4R)-leucocyanidin + NADP+ 1.1.1.219 dihydroflavonol 4-reductase
–
16-ketotestosterone + NADPH <=> 16alpha-hydroxytestosterone + NADP+ 1.1.1.147 16alpha-hydroxysteroid dehydrogenase
–
cholesterol + NADPH + H+ + O2 <=> 22-hydroxycholesterol + NADP+ + H2O 1.14.99.B1
–
2-nitrobenzaldehyde + NADP+ + H2O <=> 2-nitrobenzoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
–
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH <=> 4,4-dimethyl-5alpha-cholesta-8,14-dien-3beta-ol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
5alpha-cholesta-8,14-dien-3beta-ol + NADP+ <=> 5alpha-cholesta-8-en-3beta-ol + NADP+ 1.3.1.70 Delta14-sterol reductase
–
6-methyl-2-heptanol + NADP+ <=> 6-methyl-2-heptanone + NADPH 1.1.1.80 isopropanol dehydrogenase (NADP+)
–
NADPH + 3-acetylpyridine_adenine_dinucleotide <=> NADP+ + acetylpyridine-NADH 1.6.1.3 NAD(P)+ transhydrogenase
–
geranylgeranial + NADPH + H+ <=> geranylgeraniol + NADP+ 1.1.1.21 aldose reductase
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
–
11beta,17-dihydroxy-pregn-4-ene-3,20,21-trione + NADPH <=> 11beta,17,21-trihydroxy-pregn-4-ene-3,20-dione + NADP+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
17,21-dihydroxy-pregn-4-ene-3,11,20-trione + NADPH <=> 11beta,17,21-trihydroxy-pregn-4-ene-3,20-dione + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
imipramine + NADPH + O2 <=> imipramine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
N-(2-fluoroethyl)nortropinone + NADPH <=> N-(2-fluoroethyl)nortropan-3-ol + NADP+ 1.1.1.206 tropinone reductase I
–
tyramine + NADPH + H+ + O2 <=> p-hydroxyphenylacetaldoxime + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
–
Undecanal + NADPH <=> undecanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
10-formyltetrahydropteroylpentaglutamate + NADP+ + H2O <=> Tetrahydropteroylpentaglutamate + CO2 + NADPH 1.5.1.6 formyltetrahydrofolate dehydrogenase
–
3-hydroxyphenylacetate + NADPH + O2 <=> 3,4-hydroxyphenylacetate + NADP+ + H2O 1.14.14.9 4-hydroxyphenylacetate 3-monooxygenase
–
3-methylmaleylacetate + NADPH <=> 4-methyl-3-oxoadipate + NADP+ 1.3.1.32 maleylacetate reductase
–
quinonoid_6,7-dimethyl-7,8-dihydropterin + NADPH <=> 6,7-dimethyltetrahydrobiopterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
Berberine + NADPH <=> canadine + NADP+ 1.5.1.31 berberine reductase
–
7,8-dihydroberberine + NADPH <=> canadine + NADP+ 1.5.1.31 berberine reductase
–
ent-kaur-16-en-19-oate + 3 NADPH + 3 H+ + 3 O2 <=> gibberellin_A12 + 3 NADP+ + 4 H2O 1.14.13.79 ent-kaurenoic acid oxidase
–
biphenyl + NADPH + H+ + O2 <=> 2-Hydroxybiphenyl + 3-hydroxybiphenyl + cis-biphenyl_dihydrodiol + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
biphenyl + NADPH + H+ + O2 <=> 2-Hydroxybiphenyl + 4-Hydroxybiphenyl + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
biphenyl + NADPH + H+ + O2 <=> cis-2,3-dihydro-2,3-dihydroxybiphenyl + 2-Hydroxybiphenyl + 3-hydroxybiphenyl + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
phenylboronic_acid + NADPH + O2 <=> phenol + BO33- + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
Benzene + NADPH + O2 <=> Cyclohexanol + phenol + hydroquinone + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
indole + NADPH + O2 <=> 7-hydroxyindole + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
4-Fluorobenzaldehyde + NADP+ + H2O <=> 4-Fluorobenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
5alpha-dihydrotestosterone + NADH <=> 5alpha-Androstane-3beta,17beta-diol + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
androstenediol + NADPH <=> 5alpha-Androstane-3beta,17beta-diol + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
choloyl-CoA + NADP+ <=> 3-oxocholoyl-CoA + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
Benzene + NADPH + O2 <=> phenol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
1.14.13.7 phenol 2-monooxygenase (NADPH)
–
–
(2E)-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+ <=> 2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + 5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone + NADP+ 1.3.1.105 2-methylene-furan-3-one reductase
–
3-Nitrophenol + 2 NADPH + 2 H+ <=> 3-hydroxyaminophenol + 2 NADP+ + H2O 1.7.1.16 nitrobenzene nitroreductase
–
dTDP-alpha-D-fucopyranose + NADPH + H+ <=> dTDP-4-dehydro-6-deoxy-D-glucose + NADP+ 1.1.1.B28
–
2 biopterin + 3 NADPH + 3 H+ <=> dihydrobiopterin + tetrahydrobiopterin + 3 NADP+ 1.5.1.33 pteridine reductase
–
1-pyrroline-4-hydroxy-2-carboxylate + NADPH <=> L-hydroxyproline + NADP+ 1.5.1.2 pyrroline-5-carboxylate reductase
–
L-arginine + pyruvate + NADPH <=> octopine + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
sepiapterin + NADPH + H+ <=> tetrahydrobiopterin + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
–
–
prostaglandin_A1 + NADP+ <=> 15-oxoprostaglandin_A1 + NADPH + H+ 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
–
5beta-pregnane-3alpha,20alpha-diol + NADP+ <=> 5beta-pregnane-3,20-dione + NADPH 1.1.1.112 indanol dehydrogenase
–
oxidized_2,6-dichlorophenolindophenol + NADH <=> reduced_2,6-dichlorophenolindophenol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
trans-trans-2,4-hexadienoyl-CoA + NADPH <=> trans-3-hexenoyl-CoA + NADP+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
–
Toluene + NADPH + O2 <=> benzyl_alcohol + Cresol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
Toluene + O2 + NADPH + cytochrome_c <=> benzyl_alcohol + H2O + NADP+ + ferricytochrome_c 1.14.14.1 unspecific monooxygenase
–
Toluene + NADPH + O2 <=> benzyl_alcohol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
1-Indanol + NADP+ <=> 3H-inden-1-ol + NADPH 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
17beta-estradiol-16-one + NADPH <=> estriol + NADP+ 1.1.1.147 16alpha-hydroxysteroid dehydrogenase
–
2-Heptanone + NADPH + H+ + O2 <=> methyl_caproate + NADP+ + H2O 1.14.13.226 acetone monooxygenase (methyl acetate-forming)
–
Fe(III)-vibriobactin + NADPH + H+ <=> Fe2+ + vibriobactin + NADP+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
Fe(III)-diethylenetriamine-N,N,N'',N'''',N''''-pentaacetate + NADPH + H+ <=> Fe2+ + diethylenetriamine-N,N,N'',N'''',N''''-pentaacetate + NADP+ + H+ 1.16.1.9 ferric-chelate reductase (NADPH)
1.18.1.2 ferredoxin---NADP+ reductase
–
–
Fe(III)-(N-2,3-dihydroxybenzoyl-Gly-Thr)3 + NADPH + H+ <=> Fe2+ + (2,3-dihydroxybenzoyl-Gly-Thr)3 + NADP+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
Fe(III)-dicitrate + NADPH + H+ <=> Fe2+ + citrate + NADP+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
Fe(III)-aerobactin + NADPH + H+ <=> Fe2+ + aerobactin + NADP+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
heme + NADPH + O2 <=> biliverdin_IXdelta + Biliverdin + Fe2+ + CO + NADP+ + H2O 1.14.14.18 heme oxygenase (biliverdin-producing)
–
Fe(III)-EDTA + NADPH + H+ <=> Fe2+ + EDTA + NADP+ 1.16.1.9 ferric-chelate reductase (NADPH)
1.18.1.2 ferredoxin---NADP+ reductase
–
–
Fe(III)-nitrilotriacetic_acid + NADPH + H+ <=> Fe2+ + nitrilotriacetate + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
–
an_Fe(III)-siderophore + NADPH <=> Fe2+ + an_apo-siderophore + NADP+ + H+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
Fe(III)-enterobactin + NADPH + H+ <=> Fe2+ + enterobactin + NADP+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
oxidized_ferredoxin + NADPH + cytochrome_c <=> reduced_ferredoxin + NADP+ + ferricytochrome_c 1.18.1.2 ferredoxin---NADP+ reductase
–
crotyl_alcohol + NADP+ <=> crotonaldehyde + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
–
(S)-3-hydroxy-3-methylglutaryl-CoA + NADPH <=> mevaldyl-CoA + NADP+ 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
–
3-keto-6-phosphono-D-gluconate + NADP+ <=> D-ribulose_5-phosphate + CO2 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
–
D-xylonate + NADPH <=> D-threo-pent-2-ulosonate + NADP+ 1.1.1.215 gluconate 2-dehydrogenase
–
ethyl_4-chloro-3-oxobutanoate + NADPH <=> ethyl_4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
ketoisophorone + NADPH + H+ <=> (6R)-levodione + NADP+ 1.3.1.31 2-enoate reductase
1.3.1.42 12-oxophytodienoate reductase
1.6.99.1 NADPH dehydrogenase
–
–
–
pelargonidin + NADPH <=> (-)-epiafzelechin + afzelechin + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
2-Heptanone + NADPH + O2 <=> pentyl_acetate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
duroquinone + NADPH <=> tetramethyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
–
–
acetoacetyl-CoA + NADPH <=> (R)-3-hydroxybutyryl-CoA + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
1.1.1.36 acetoacetyl-CoA reductase
–
–
dabsyl-L-methionine_(S)-sulfoxide + NADPH + H+ <=> dabsyl-L-methionine + NADP+ + H2O 1.8.4.11 peptide-methionine (S)-S-oxide reductase
–
2-Methoxybenzaldehyde + NADP+ + H2O <=> 2-Methoxybenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
crotonyl-CoA + NADH <=> butyryl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
vinylacetyl-CoA + NADPH <=> butyryl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
ethylbenzene + NADPH + H+ + O2 <=> 1-phenylethanol + 3-Ethylphenol + 4-Ethylphenol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
D-galactonate + NADP+ <=> D-lyxo-hex-2-ulosonate + NADPH 1.1.1.215 gluconate 2-dehydrogenase
–
NADPH + deamido-NAD+ <=> NADP+ + deamino-NADH 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
1.6.1.3 NAD(P)+ transhydrogenase
–
–
nitracrine + NADPH_+ <=> nitracrine + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
isobutanol + NADP+ <=> isobutanol + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
stearoyl-CoA + NADPH <=> octadecanal + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
octadecanal + NADP+ <=> fatty_acid + NADPH + H+ 1.2.1.48 long-chain-aldehyde dehydrogenase
–
2-trans-octadecenal + NADPH <=> octadecanal + NADP+ 1.3.1.27 2-hexadecenal reductase
–
dehydroepiandrosterone + NADPH <=> dehydroepiandrosterone + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
ferricyanide + NADPH + O2 <=> ferrocyanide + NO + NADP+ 1.14.13.39 nitric-oxide synthase (NADPH)
–
ferricytochrome_c + NADPH + O2 <=> ferricytochrome_c + NO + NADP+ 1.14.13.39 nitric-oxide synthase (NADPH)
–
NO + NADP+ + H+ <=> N2O + NADP+ + H2O 1.7.1.14 nitric oxide reductase [NAD(P)+, nitrous oxide-forming]
–
phenylacetone + NADPH + H+ <=> 1-phenyl-1-propanol + NADP+ 1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.B4
–
–
propiophenone + NADPH <=> 1-phenyl-1-propanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
Prostaglandin_D2 + NADPH <=> 9alpha,11alpha-prostaglandin_F2alpha + NADP+ 1.1.1.188 prostaglandin-F synthase
–
prostaglandin_H2 + NADPH <=> 9alpha,11alpha-prostaglandin_F2alpha + NADP+ 1.1.1.188 prostaglandin-F synthase
–
4-chloroacetophenone + NADPH <=> 1-(4-chlorophenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
epiandrosterone + NADPH <=> androstane-3beta,17beta-diol + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
androsterone + NADPH <=> androstane-3beta,17beta-diol + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
5alpha-dihydrotestosterone + NADPH + H+ <=> androstane-3beta,17beta-diol + NADP+ 1.1.1.62 17beta-estradiol 17-dehydrogenase
–
2,4-hexadienal + NADPH <=> 2,4-hexadien-1-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
5-hydroxyconiferaldehyde + NADP+ <=> dihydro-5-hydroxyconiferyl_aldehyde + NADPH + H+ 1.3.1.102 2-alkenal reductase (NADP+)
–
5-hydroxyconiferaldehyde + NADP+ <=> 5-hydroxyconiferyl_alcohol + NADPH + H+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
isocitrate + NADP+ <=> 2-oxoglutarate + NADPH + H+ 1.1.1.42 isocitrate dehydrogenase (NADP+)
–
3-Hydroxy-4-methoxybenzaldehyde + NADPH + H+ <=> isovanillyl_alcohol + NADP+ 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
phenanthrene + NADPH + H+ + O2 <=> phenanthrene_3,4-dihydrodiol + 4-phenanthrol + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
1-phenylethanol + NADP+ <=> (R)-1-phenylethanol + (S)-1-phenylethanol + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
acetophenone + NADPH <=> 1-phenylethanol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.320 benzil reductase [(S)-benzoin forming]
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.B4
–
–
–
–
–
–
–
–
1-phenylethanol + NADP+ <=> acetophenone + (R)-1-phenylethanol + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
narbomycin + NADPH + H+ + O2 <=> pikromycin + NADP+ + H2O 1.14.13.185 pikromycin synthase
–
beta-ionone + NADPH + O2 <=> 4-hydroxy-beta-ionone + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
N-Hydroxy-4-acetylaminobiphenyl + NADPH <=> N-acetyl-4-aminobiphenyl + NADP+ + H2O 1.7.1.12 N-hydroxy-2-acetamidofluorene reductase
–
3-Pentanone + NADPH + H+ <=> 3-Pentanol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.80 isopropanol dehydrogenase (NADP+)
–
–
D-ribose_5-phosphate + NADPH <=> D-ribitol_5-phosphate + NADP+ 1.1.1.21 aldose reductase
–
2-oxobutyrate + NADPH + H+ <=> DL-2-hydroxybutyrate + NADP+ 1.1.1.110 aromatic 2-oxoacid reductase
1.1.1.184 carbonyl reductase (NADPH)
–
–
DELTA1-pyrroline-2-carboxylate + NADPH + H+ <=> L-pipecolic_acid + NADP+ 1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
–
piperideine-6-carboxylate + NADPH + H+ <=> L-pipecolic_acid + NADP+ 1.5.1.2 pyrroline-5-carboxylate reductase
–
testosterone + NADP+ <=> 4-androstene-3,17-dione + NADH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
5beta-dihydrotestosterone + NADPH + H+ <=> testosterone + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
androstenediol + NADPH + H+ <=> testosterone + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
myristoyl-CoA + NADPH <=> Tetradecanal + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
Tetradecanal + NADP+ <=> myristic_acid + NADPH 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
2-trans-tetradecenal + NADPH <=> Tetradecanal + NADP+ 1.3.1.27 2-hexadecenal reductase
–
progesterone + NADP+ <=> 20beta-hydroxyprogesterone + NADPH + H+ 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
20alpha-hydroxyprogesterone + NADPH + H+ <=> progesterone + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
–
pregnenolone + NADPH <=> progesterone + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
UTP + NAD+ <=> UDP + NADP+ 2.7.1.23 NAD+ kinase
–
sphinganine + NADPH + H+ + O2 <=> phytosphingosine + NADP+ + H2O 1.14.18.5 sphingolipid C4-monooxygenase
–
2-methyl-N-phenylmaleimide + NADPH <=> (3R)-3-methyl-1-phenylpyrrolidine-2,5-dione + NADP+ 1.3.1.31 2-enoate reductase
1.3.1.42 12-oxophytodienoate reductase
–
–
sulindac + NADPH <=> sulindac_sulfide + NADP+ + H2O 1.8.4.13 L-methionine (S)-S-oxide reductase
–
4-hydroxybenzoate + NADPH + ferricyanide <=> 3,4-dihydroxybenzoate + NADP+ + ferrocyanide 1.14.13.2 4-hydroxybenzoate 3-monooxygenase
–
ferricyanide + NADPH + O2 <=> ferrocyanide + NADP+ + H2O 1.14.13.39 nitric-oxide synthase (NADPH)
–
ferrocyanide + NADP+ + H+ <=> ferrocyanide + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
2 ferrocyanide + NADP+ <=> 2 oxidized_ferricyanide + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
Plumbagin + NADPH <=> reduced_plumbagin + NADP+ 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
–
–
–
esonarimod + NADPH + H+ + O2 <=> 4-(4-methylphenyl)-2-methylsulfanylmethyl-4-oxobutyric_acid + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
butyrophenone + NADPH + H+ <=> (S)-phenyl-1-butanol + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
–
–
5beta-pregnane-3beta,20alpha-diol + NADP+ <=> 5beta-pregnane-20alpha-ol-3-one + NADPH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
–
progesterone + NADPH + O2 <=> 16alpha-hydroxyprogesterone + 2beta,16alpha-dihydroxyprogesterone + NADP+ + H2O 1.14.99.4 progesterone monooxygenase
–
cyclohexene + NADPH + O2 <=> epoxycyclohexane + 2-Cyclohexen-1-ol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
2-Cyclohexen-1-ol + NADP+ <=> 2-cyclohexen-1-one + NADH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
4-methylacetophenone + NADPH <=> 1-(4-methylphenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
D-ribose + NADP+ <=> D-ribonolactone + NADPH 1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
1.1.1.B35
–
–
–
D-ribose + NADP+ <=> D-ribono-1,5-lactone + NADPH 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
isopentane + NADH + O2 <=> 2-methylbutanol + 3-methyl-1-butanol + 2-methyl-2-butanol + 3-methylbutan-2-ol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
isopentane + NADPH + O2 <=> 2-methylbutanol + 3-methyl-1-butanol + 2-methyl-2-butanol + 3-methylbutan-2-ol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
3-methyl-1-butanol + NADP+ <=> 3-methyl-1-butanol + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
–
nitrated_DNA + NADPH <=> DNA + NADP+ + H2O 1.8.1.4 dihydrolipoyl dehydrogenase
–
2-ethylcyclohexanone + NADPH + O2 <=> Benzyl_acetate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
2-indanone + NADPH + O2 <=> dihydrocoumarin + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
5alpha-androstane-3beta,7beta,17beta-triol + NADP+ <=> 5alpha-androstane-3beta,7alpha,17beta-triol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
7beta-hydroxydehydroepiandrosterone + NADP+ <=> 7alpha-hydroxydehydroepiandrosterone + 7-oxo-dehydroepiandrosterone + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
lupeol + 3 O2 + 3 NADPH + 3 H+ <=> betulinic_acid + 3 NADP+ + 4 H2O 1.14.14.126 beta-amyrin 28-monooxygenase
–
2-phenyl-2-propenal + NADPH + H+ <=> 2-phenyl-1-propanol + NADP+ 1.1.1.21 aldose reductase
–
2-n-hexylcyclopentanone + NADPH + H+ + O2 <=> delta-undecanolactone + NADP+ + H2O 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
2 1,4-naphthosemiquinone + NADPH + H+ <=> 2 1,4-naphthosemiquinone + NADP+ 1.6.5.5 NADPH:quinone reductase
–
1,4-Naphthoquinone + NADPH + H+ <=> 1,4-naphthosemiquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
–
–
3-methyl-2-oxopentanoate + NADPH + NH3 <=> L-isoleucine + NADP+ + H2O 1.4.1.2 glutamate dehydrogenase
–
2-Fluorobenzaldehyde + NADP+ + H2O <=> 2-Fluorobenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
4-nitrobenzaldehyde + NADPH + H+ <=> 4-nitrobenzoate + NADP+ 1.1.1.317 perakine reductase
–
Sulfide + Polysulfide + NADP+ <=> (sulfide)n+1 + NADPH + H+ 1.8.1.19 sulfide dehydrogenase
–
polysulfide(n) + NADPH + H+ <=> Sulfide + polysulfide(n-1) + NADP+ 1.8.1.18 NAD(P)H sulfur oxidoreductase (CoA-dependent)
–
L-erythro-3,5-diaminohexanoate + H2O + NADP+ <=> (S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+ 1.4.1.B2
–
L-erythro-3,5-diaminohexanoate + H2O + NADP+ <=> 5-amino-3-oxohexanoate + NH3 + NADPH + H+ 1.4.1.B2
–
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+ <=> (2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+ 1.1.1.B18
–
2-hydroxyacetophenone + NADPH + H+ <=> (R)-1-phenyl-1,2-ethanediol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
Phenylglyoxal + 2 NADPH + 2 H+ <=> (R)-1-phenyl-1,2-ethanediol + 2 NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> 24-oxo-25-hydroxycholecalciferol + 23(S),25-dihydroxyvitamin_D3 + secalciferol + 24-oxo-23(S),25-dihydoxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
2 (R)-pulegone + 2 NADPH + 2 H+ <=> (-)-menthone + (+)-isomenthone + 2 NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
1.3.1.81 (+)-pulegone reductase
–
–
(-)-menthone + NADP+ <=> (-)-menthol + (+)-isomenthol + NADPH + H+ 1.3.1.82 (-)-isopiperitenone reductase
–
corticosterone + NADPH + H+ <=> 11-Dehydrocorticosterone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
4,4''-diaponeurosporen-4-al + NADP+ <=> 4,4''-diaponeurosporenoic_acid + NADPH + H+ 1.2.1.B23
–
B
Oxidized_benzyl_viologen + NADPH <=> reduced_benzyl_viologen + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.4 rubredoxin---NAD(P)+ reductase
–
–
3-Fluorobenzaldehyde + NADP+ + H2O <=> 3-Fluorobenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
3-Indole-2-oxopropanoate + NADPH <=> 3-indolelactate + NADP+ 1.1.1.110 aromatic 2-oxoacid reductase
–
5alpha-dihydroprogesterone + NADPH + H+ <=> allopregnanolone + 5alpha-pregnan-20alpha-ol-3-one + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
5alpha-dihydroprogesterone + NADPH + H* <=> allopregnanolone + 5alpha-pregnan-20alpha-ol-3-one + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
progesterone + NADPH <=> allopregnanolone + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
chanoclavine-I_aldehyde + glutathione + NADPH + H+ <=> agroclavine + GSSG + NADP+ 1.5.1.46 agroclavine dehydrogenase
–
(1''S)-averantin + NADPH + H+ + O2 <=> (1''S,5''R)-5''-hydroxyaverantin + NADP+ + H2O 1.14.14.116 averantin hydroxylase
–
3alpha-hydroxydesogestrel + NADP+ <=> 3-oxodesogestrel + NADPH + H+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
(1R,2S,4S)-neoisodihydrocarveol + NADP+ <=> (1R,4S)-isodihydrocarvone + NADPH + H+ 1.3.1.102 2-alkenal reductase (NADP+)
–
Cyclobutanone + NADPH + O2 <=> gamma-butyrolactone + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
hexaphosphate + NAD+ <=> (phosphate)5 + NADP+ 2.7.1.23 NAD+ kinase
–
2-hexenoyl-[acyl-carrier_protein] + NADPH <=> hexanoyl-[acyl-carrier_protein] + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
2-oxoisovalerate + NADPH <=> Isovalerate + NADP+ 1.1.1.110 aromatic 2-oxoacid reductase
–
terephthalate + NADPH + O2 + H+ <=> (1R,2S)-1,2-Dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate + NADP+ 1.14.12.15 terephthalate 1,2-dioxygenase
–
2,4,6-tribromophenol + NADPH + O2 <=> 2,6-dibromo-p-hydroquinone + Br- + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
3-bromo-L-Tyr + NADP+ + Br- <=> 3,5-Dibromo-L-tyrosine + NADPH + H+ 1.21.1.1 iodotyrosine deiodinase
–
1,2,3-Butanetriol + NADP+ <=> 1,3-Dihydroxybutane-2-one + NADPH 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
–
acetoin + NADPH <=> 1,2,3-Butanetriol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Lanthionine_ketimine + NADPH <=> 1,4-Thiomorpholine_3,5-dicarboxylic_acid + NADP+ 1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
2-phenylcyclohexanone + NADPH + O2 <=> 1-Oxa-2-oxo-3-phenylcycloheptane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
2-oxopropyl-CoM + NADPH + H+ <=> acetone + coenzyme_M + NADP+ 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)
–
Cyclooctanone + NADPH + O2 <=> 1-oxa-2-oxo-cyclononane + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
Cycloheptanone + NADPH + O2 <=> 1-oxa-2-oxo-cyclooctane + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
11-hydroxy-9,15-dioxoprosta-5,13-dien-1-oic_acid + NADPH <=> 11-Hydroxy-9,15-dioxoprosta-5-en-1-oic_acid + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
16-epiestriol + NADP+ <=> 16-ketoestradiol + NADPH 1.1.1.147 16alpha-hydroxysteroid dehydrogenase
–
NADPH + thio-NADP+ + H+ <=> NADP+ + thio-NADPH + H+ 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
–
3-buten-2-one + NADPH <=> acetone + NADP+ 1.3.1.74 2-alkenal reductase [NAD(P)+]
–
acetone + NADP+ <=> 2-propanol + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
acetoin + 2 NADPH + 2 H+ <=> (2R,3R)-butane-2,3-diol + meso-2,3-butanediol + 2 NADP+ 1.1.1.4 (R,R)-butanediol dehydrogenase
–
(R)-acetoin + NADPH + H+ <=> meso-2,3-butanediol + NADP+ 1.1.1.B20
–
meso-2,3-butanediol + NADP+ <=> (S)-acetoin + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
acetoin + NADPH <=> meso-2,3-butanediol + meso-2,3-butanediol + NADP+ 1.1.1.76 (S,S)-butanediol dehydrogenase
1.1.1.B20
1.1.1.B35
–
–
–
Uracil + NADP+ <=> 5,6-dihydrouracil + NADPH + H+ 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
3,4-dimethoxy-cinnamyl_alcohol + NADP+ <=> 3,4-dimethoxycinnamaldehyde + NADPH 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
cis-1,3-Dimethylcyclohexane + NADPH + O2 <=> 3,5-Dimethylcyclohexanol + 1-cis-3-dimethylcyclohexanol + NADP+ + H2O + 1-trans-3-dimethylcyclohexanol 1.14.13.25 methane monooxygenase (soluble)
–
3-O-Methyl-17beta-estradiol + NADP+ <=> 3-methyl-O-estrone + NADPH 1.1.1.62 17beta-estradiol 17-dehydrogenase
–
5beta-Dihydrocortisone + NADPH <=> 3alpha,17alpha,21-trihydroxy-5beta-pregnan-11,20-dione + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
FMN + NADH <=> FMNH2 + NADP+ 1.5.1.30 flavin reductase (NADPH)
–
4-Aminobenzyl_alcohol + NADP+ <=> 4-Aminobenzaldehyde + NADPH 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
5,10-Methylenetetrahydropteroate + NADP+ <=> 5,10-Methenyltetrahydropteroate + NADPH 1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
–
6-endo-hydroxycineole + NADP+ <=> 6-Oxocineole + NADPH 1.1.1.241 6-endo-hydroxycineole dehydrogenase
–
1,8-cineole + NADPH + H+ + O2 <=> 6-endo-hydroxycineole + NADP+ + H2O 1.14.13.156 1,8-cineole 2-endo-monooxygenase
–
17beta-estradiol + NADPH + O2 <=> 6beta-Hydroxyestradiol-17beta + NADP+ + H2O 1.14.99.11 estradiol 6beta-monooxygenase
–
L-gulonate + NADPH <=> D-glucuronate + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
D-glucuronate + NADP+ <=> D-glucurono-1,5-lactone + NADPH 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
N,N-dimethylbenzylamine + NADPH + O2 <=> Benzyldimethylamine_N-oxide + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
(-)-beta-pinene + NADPH + O2 <=> 6,6-Dimethylbicyclo[3.1.1]hept-2-ene-2-methanol + beta-Pinene_oxide + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
crotonaldehyde + NADPH <=> cis-2-buten-1-ol + NADP+ 1.1.1.283 methylglyoxal reductase (NADPH)
–
Cystathionine_ketimine + NADPH <=> Cyclothionine + NADP+ 1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
Diethyl_2-methyl-3-oxosuccinate + NADPH <=> Diethyl_2-methyl-3-hydroxysuccinate + NADP+ 1.1.1.229 diethyl 2-methyl-3-oxosuccinate reductase
–
DL-aspartate-4-semialdehyde + NADPH + H+ <=> L-homoserine + NADP+ 1.1.1.3 homoserine dehydrogenase
–
2-methylbutanal + NADP+ + H2O <=> 2-methylbutanoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
–
canavanine + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-canavanine + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
L-canavanine + pyruvate + NADPH + H+ <=> N2-(D-1-Carboxyethyl)-canavanine + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
homoarginine + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-homoarginine + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
N2-(D-1-Carboxyethyl)-L-Orn + NADP+ + H2O <=> L-ornithine + pyruvate + NADPH 1.5.1.11 D-octopine dehydrogenase
1.5.1.16 D-lysopine dehydrogenase
–
–
L-arginine + 2-oxobutyrate + NADPH <=> N2-(D-2-Carboxypropyl)-L-Arg + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
4-guanidinobutyraldehyde + NADP+ + H2O <=> 4-Guanidinobutyrate + NADPH 1.2.1.19 aminobutyraldehyde dehydrogenase
–
oleyl_aldehyde + NADPH <=> oleyl_alcohol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
D-glucose_6-phosphate + NAD+ <=> 6-phospho-D-glucono-1,5-lactone + NADP+ + H+ 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
R1-CO-CO-R2 + NADPH <=> R1-CO-CHOH-R2 + NADP+ 1.1.1.185 L-glycol dehydrogenase
–
benzil + NADPH + H+ <=> Benzoin + NADP+ 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
Scopine + NADP+ <=> scopinone + NADPH 1.1.1.206 tropinone reductase I
–
sitosterol + NADPH + H+ + O2 <=> stigmasta-5,22-dien-3beta-ol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
D-xylose_5-phosphate + NADPH <=> xylitol_5-phosphate + NADP+ 1.1.1.21 aldose reductase
–
Fusidic_acid + NADP+ <=> (2Z)-2-[(4alpha,5alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-11-hydroxy-4,8,10,14-tetramethyl-3-oxogonan-17-ylidene]-6-methylhept-5-enoic_acid + NADPH + H+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
glycolithocholic_acid + NADP+ <=> 3-oxo-5beta-cholanoyl_glycine + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
–
–
glycolithocholic_acid + NADP+ <=> 3-Oxo-glycocholanoic_acid + NADPH 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
Hexadecyldihydroxyacetone_phosphate + NADPH <=> 1-O-Hexadecyl-2-lyso-sn-glycero-3-phosphate + NADP+ 1.1.1.101 acylglycerone-phosphate reductase
–
L-alanine + pyruvate + NADPH <=> meso-Alanopine + NADP+ + H2O 1.5.1.22 strombine dehydrogenase
–
3-oxoacyl-[acyl-carrier_protein] + NADPH <=> 3-Hydroxyacyl-[acyl-carrier_protein] + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl_methyl_ester + NADP+ <=> 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl_methyl_ester + NADPH + H+ 1.1.1.176 12alpha-hydroxysteroid dehydrogenase
–
pregnenolone + NADPH <=> 5-pregnene-3beta,20beta-diol + NADP+ 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
2 benzyl_2-methyl-3-oxobutanoate + 2 NADPH + 2 H+ <=> benzyl_(2R,3S)-2-methyl-3-hydroxy-butanoate + benzyl(2S,3S)-2-methyl-3-hydroxybutanoate + 2 NADP+ 1.1.1.217 benzyl-2-methyl-hydroxybutyrate dehydrogenase
–
acetophenone + NADPH + H+ <=> (S)-1-phenylethanol + (R)-1-phenylethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
5-Keto-D-fructose_1-phosphate + NADPH <=> L-sorbose_1-phosphate + NADP+ 1.1.1.123 sorbose 5-dehydrogenase (NADP+)
–
acetophenone + NADPH + H+ <=> (S)-1-phenylethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
methyl_viologen + NADPH <=> methyl_viologen + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
sitosterol + NADPH + H+ + O2 <=> poriferasterol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
7alpha,12alpha-dihydroxy-5beta-cholestan-3-one + NADP+ <=> 5beta-cholestane-3alpha,7alpha,12alpha-triol + NADPH + H+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
xylene + NADPH + O2 <=> 2-methyl-p-cresol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
cuminaldehyde + NADP+ + H2O <=> p-isopropylbenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
7-O-methylluteone + NADPH + H+ + O2 <=> dihydrofurano_derivatives + NADP+ + H2O 1.14.99.34 monoprenyl isoflavone epoxidase
–
H2 + NADP+ <=> Sulfide + NADPH + H+ 1.12.98.4 sulfhydrogenase
–
3,4-dihydroisoquinoline + NADPH + H+ <=> 1,2,3,4-tetrahydroisoquinoline + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
1,4-Butanediol + NADP+ <=> 1,4-butanedione + NADPH 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
NADPH + 3-hydroxy-3-methyl-2-oxobutanoic_acid <=> NADP+ + 2,3-dihydroxyisovalerate 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
(S)-2-Hydroxy-2-methyl-3-oxobutanoate + NADPH + H+ <=> 2,3-dihydroxyisovalerate + NADP+ 1.1.1.383 ketol-acid reductoisomerase [NAD(P)+]
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
B
alpha-ecdysone + NADPH + O2 <=> 20-hydroxyecdysone + NADP+ + H2O 1.14.99.22 ecdysone 20-monooxygenase
–
ecdysone + NADPH + O2 <=> 20-hydroxyecdysone + NADP+ + H2O 1.14.99.22 ecdysone 20-monooxygenase
–
3-dehydro-beta-ecdysone + NADPH + H+ <=> 20-hydroxyecdysone + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
benzoate + NADPH + H+ + O2 <=> 4-hydroxybenzoate + NADP+ + H2O 1.14.14.92 benzoate 4-monooxygenase
–
4-hydroxybenzaldehyde + NADPH + H+ + O2 <=> 4-hydroxybenzoate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
N-octanoylsphinganine + NADPH + O2 + H+ <=> N-octanoylsphingosine + NADP+ + H2O 1.14.19.17 sphingolipid 4-desaturase
–
Camphorquinone + NADH <=> (1R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+ 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
Camphorquinone + NADPH + H+ <=> (1R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
16alpha-methyl-1,2-dehydrocortisone + NADPH <=> 16alpha-methyl-1,2-dehydrocortisol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
cholestanone + NADPH <=> cholestanol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
(R)-3-hydroxy-3-methyl-5-oxovaleric_acid + NADPH <=> (R)-3-hydroxy-3-methyl-5-hydroxyvaleric_acid + NADP+ 1.1.1.32 mevaldate reductase
1.1.1.33 mevaldate reductase (NADPH)
–
–
11beta,17-dihydroxy-pregn-4,11-diene-3,20,21-trione + NADPH <=> 11beta,17,21-trihydroxy-pregn-4,11-diene-3,20-dione + NADP+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
4,4''-dichlorobiphenyl + NADPH + O2 <=> 2,3-dihydroxy-4,4''-dichlorobiphenyl + NADP+ 1.14.12.18 biphenyl 2,3-dioxygenase
–
2-methoxy-6-oxo-6-phenylhexa-2,3-dienoic_acid_methyl_ester + NADPH <=> 2-methoxy-6-oxo-6-phenylhexa-2-enoic_acid_methyl_ester + NADP+ 1.3.1.40 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
–
2-methoxy-6-oxo-6-phenylhexa-2,4-dienoic_acid_methyl_ester + NADPH <=> 2-methoxy-6-oxo-6-phenylhexa-2-enoic_acid_methyl_ester + NADP+ 1.3.1.40 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
–
glycochenodeoxycholic_acid + NADP+ <=> 7alpha-hydroxy-3-oxo-5beta-cholanoyl_glycine + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
–
glycochenodeoxycholic_acid + NADP+ <=> 3alpha-Hydroxy-7-keto-5beta-cholanoyl_glycine + NADPH 1.1.1.159 7alpha-hydroxysteroid dehydrogenase
–
3,4-Dihydroxybenzaldehyde + NADPH <=> 3,4-dihydroxybenzyl_alcohol + NADP+ 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
3,5-dimethoxy-benzaldehyde + NADPH <=> 3,5-dimethoxybenzyl_alcohol + NADP+ 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
3-chloro-2-buten-1-ol + NADP+ <=> 3-chloro-2-butenaldehyde + NADPH 1.1.1.54 allyl-alcohol dehydrogenase
–
5alpha-dihydrotestosterone + NADPH <=> 3alpha,17beta-dihydroxy-5alpha-androstan + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
4-hydroxy-2-hexenal + NADPH <=> 4-hydroxyhexanal + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.6.5.5 NADPH:quinone reductase
–
–
5-Iodouracil + NADPH <=> 5-iodo-5,6-dihydrouracil + NADP+ 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
5alpha-cholesta-7,14-dien-3beta-ol + NADPH <=> 5alpha-cholesta-7-en-3beta-ol + NADP+ 1.3.1.70 Delta14-sterol reductase
–
5alpha-cholesta-7,24-dien-3beta-ol + NADPH <=> 5alpha-cholesta-7-en-3beta-ol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
5beta-Pregnan-3beta-ol-20-one + NADPH + H+ <=> 5beta-pregnan-3,20-diol + NADP+ 1.1.1.112 indanol dehydrogenase
–
5beta-pregnan-3,20-diol + NADP+ <=> 5beta-pregnane-20alpha-ol-3-one + NADPH 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
7-hydroxytropinone + NADPH <=> 6-methoxy-2-naphthoic_acid + NADP+ 1.1.1.206 tropinone reductase I
–
behenoyl-CoA + NADPH <=> behenic_aldehyde + NADP+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
–
cortisone + NADPH <=> cortisole + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
m-cresol + NADPH + O2 <=> 3-methylcatechol + 4-methylcatechol + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
2 o-Cresol + NADPH + O2 <=> 3-methylcatechol + 4-methylcatechol + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
cholesta-5,7-dien-3alpha-ol + NADPH <=> epicholesterol + NADP+ 1.3.1.21 7-dehydrocholesterol reductase
–
L-rhamnose + NADPH <=> fucitol + NADP+ 1.1.1.21 aldose reductase
–
L-fucose + NADPH <=> fucitol + NADP+ 1.1.1.21 aldose reductase
–
D-fucose + NADPH <=> fucitol + NADP+ 1.1.1.21 aldose reductase
–
Phenylglyoxal + NADPH <=> hydroxyphenylacetaldehyde + NADP+ 1.1.1.283 methylglyoxal reductase (NADPH)
–
4-Methyl-2-nitrophenol + NADPH + O2 <=> 4-methylcatechol + NADP+ + H2O 1.14.13.31 2-nitrophenol 2-monooxygenase
–
5-methyl-2-nitrophenol + NADPH + O2 <=> 4-methylcatechol + NADP+ + H2O 1.14.13.31 2-nitrophenol 2-monooxygenase
–
n-Alkane + NADPH + H+ + O2 <=> n-alkanol + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
(-)-alpha-pinene + NADPH + H+ + O2 <=> R-(+)-cis-verbenol + NADP+ + H2O 1.14.14.31 ipsdienol synthase
–
S-(-)-2-methylbutan-1-ol + NADP+ <=> (2S)-2-methylbutanal + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
–
S-(-)-2-methylbutan-1-ol + NADP+ <=> (2S)-methylbutanal + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
–
(2E,6Z)-nonadienal + NADPH + H+ <=> trans-2,cis-6-nonadienol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
cortisone + NADPH <=> 11beta,21dihydroxy-pregnan-3,11,20-trione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
Prostaglandin_D2 + NADPH <=> (5Z,13E)-(15S)-9alpha,11beta,15-trihydroxyprosta-5,13-dienoate + NADP+ 1.1.1.188 prostaglandin-F synthase
–
10-formyltetrahydropteroylpolyglutamate + NADP+ + H2O <=> tetrahydropteroylpolyglutamate + CO2 + NADPH + H+ 1.5.1.6 formyltetrahydrofolate dehydrogenase
–
4-bromobenzaldehyde + NADP+ + H2O <=> 4-Bromobenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
2-Fluorobenzaldehyde + NADPH + H+ <=> 2-fluorobenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
2-methoxy-1,4-benzoquinone + NADPH <=> 2-methoxyhydroquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-sec-Butylphenol + NADPH + O2 <=> 2-sec-butylcatechol + NADP+ + H2O 1.14.13.44 2-hydroxybiphenyl 3-monooxygenase
–
NADP+ + reduced_methyl_viologen <=> NADPH + methyl_viologen 1.18.1.2 ferredoxin---NADP+ reductase
1.8.1.2 assimilatory sulfite reductase (NADPH)
–
–
propylene + NADH + O2 <=> propylene_oxide + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
propylene + NADPH + O2 <=> propylene_oxide + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
5-hydroxycyclohex-1-enecarbonyl-CoA + NADP+ <=> 5-hydroxycyclohexylcarbonyl-CoA + NADPH + H+ 1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+)
–
3-keto-5alpha-androstane_steroids + NADPH <=> 5alpha-androstane-3beta-ol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
dibenzothiophene + NADPH + H+ + O2 <=> dibenzothiophene_sulfoxide + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
2-octenoyl-CoA + NADH <=> octanoyl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
2-cis-octenoyl-CoA + NADPH + H+ <=> octanoyl-CoA + NADP+ 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
12-oxo-trans-phythodienoic_acid + alpha-NADPH <=> trans-3-oxo-2-(2''-pentenyl)cyclopentaneoctanoic_acid + NADP+ 1.3.1.42 12-oxophytodienoate reductase
–
12-oxo-trans-phythodienoic_acid + NADPH <=> trans-3-oxo-2-(2''-pentenyl)cyclopentaneoctanoic_acid + NADP+ 1.3.1.42 12-oxophytodienoate reductase
–
[6R]methylenetetrahydropteroyldiglutamate + NADP+ <=> 5,10-methenyltetrahydropteroylpoly-L-glutamate + NADPH + H+ 1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
–
(S)-2-amino-6-oxohexanoate + holo-[LYS2_peptidyl-carrier-protein] + NADP+ <=> L-2-aminoadipyl-[LYS2_peptidyl-carrier-protein] + NADPH + H+ 1.2.1.95 L-2-aminoadipate reductase
–
Fe(III)-EDTA + NADPH <=> Fe(III)-EDTA + NADP+ 1.16.1.10 ferric-chelate reductase [NAD(P)H]
1.18.1.2 ferredoxin---NADP+ reductase
–
–
3,4-Dihydroxyphenylpyruvate + NADPH + H+ <=> 3-(3,4-Dihydroxyphenyl)lactate + NADP+ 1.1.1.237 hydroxyphenylpyruvate reductase
–
5alpha-Androstan-3beta-ol-17-one + NADP+ <=> 5alpha-Androstan-3,17-dione + NADPH 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
–
trans-2-hexenoyl-CoA + NADH <=> hexanoyl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
5beta-Pregnan-3beta-ol-20-one + NADP+ <=> 5alpha-dihydroprogesterone + NADPH + H+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
7-dehydrocholesterol + NADPH + H+ <=> 7-oxocholesterol + NADP+ + H2O 1.14.14.23 cholesterol 7alpha-monooxygenase
–
7-oxocholesterol + NADP+ <=> 7beta-hydroxycholesterol + NADPH + H+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
Metyrapone + NADPH + H+ <=> 7alpha-hydroxycholesterol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
metapyrone + NADPH + H+ <=> 7alpha-hydroxycholesterol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
pelargonidin + 2 NADPH + 2 H+ <=> afzelechin + (+)-epiafzelechin + 2 NADP+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
–
D-sorbitol_6-phosphate + NADP+ <=> D-fructose_6-phosphate + NADPH + H+ 1.1.1.140 sorbitol-6-phosphate 2-dehydrogenase
–
GDP-4-dehydro-6-deoxy-D-mannose + NADPH <=> GDP-D-fucose + NADP+ 1.1.1.271 GDP-L-fucose synthase
–
L-3-hydroxybutyrate + NADP+ <=> acetoacetate + NADPH 1.1.1.276 serine 3-dehydrogenase (NADP+)
–
2-Pentanone + NADPH + H+ + O2 <=> methyl_butyrate + NADP+ + H2O 1.14.13.226 acetone monooxygenase (methyl acetate-forming)
–
heptanophenone + NADPH <=> (S)-(-)-1-phenyl-1-heptanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
riboflavin + NADH <=> reduced_riboflavin + NADP+ 1.5.1.30 flavin reductase (NADPH)
–
oxidized_riboflavin + NADPH + H+ <=> reduced_riboflavin + NADP+ 1.5.1.30 flavin reductase (NADPH)
–
tridecanal + NADPH <=> 1-tridecanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
5,10-methylenetetrahydrofolate + NADP+ <=> 5,10-methenyltetrahydropteroylglutamate + NADPH + H+ 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
–
–
Methylene_cyclohexane + NADPH + O2 <=> cyclohexylmethanol + methylene_cyclohexane_oxide + 4-hydroxymethylene_cyclohexane + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
D-glucose + NADP+ <=> D-glucoselactone + NADPH + H+ 1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
–
S-adenosyl-L-methionine + Berberine + NADPH + H+ <=> S-adenosyl-L-homocysteine + corydaline + NADP+ 2.1.1.147 corydaline synthase
–
S-adenosyl-L-methionine + Columbamine + NADPH + H+ <=> S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine + NADP+ 2.1.1.147 corydaline synthase
–
S-adenosyl-L-methionine + Jatrorrhizine + NADPH + H+ <=> S-adenosyl-L-homocysteine + 7,8-dehydrothalictricavine + NADP+ 2.1.1.147 corydaline synthase
–
S-adenosyl-L-methionine + coptisine + NADPH + H+ <=> S-adenosyl-L-homocysteine + tetrahydrocorysamine + NADP+ 2.1.1.147 corydaline synthase
–
S-adenosyl-L-methionine + 7,8-dihydroberberine + NADPH + H+ <=> S-adenosyl-L-homocysteine + thalictricavine + NADP+ 2.1.1.147 corydaline synthase
–
2 [methionine_synthase]-methylcob(III)alamin + 2 S-adenosyl-L-homocysteine + NADP+ <=> 2 [Methionine_synthase]-cob(II)alamin + NADPH + H+ + 2 S-adenosyl-L-methionine 1.16.1.8 [methionine synthase] reductase
–
syringaldehyde + NADP+ + H2O <=> syringic_acid + NADPH + 2 H+ 1.2.1.67 vanillin dehydrogenase
–
Protopheophorbide + NADPH + H+ <=> pheophorbide_a + NADP+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
24-methylenecycloartanone + NADPH <=> 24(28)-methylene_cycloartanol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
beta-carotene + NADPH + O2 <=> echinenone + NADP+ + H2O 1.3.5.B4
–
3-Mercaptopropionate + acetoacetate + NADP+ <=> 3-(2-oxopropylthio)propionate + CO2 + NADPH + H+ 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)
–
3-mercaptopropanesulfonate + acetoacetate + NADP+ <=> 2-oxopropyl-CoM + CO2 + NADPH + H+ 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)
–
8-Ketodeoxycoformycin + NADPH <=> 2''-deoxycoformycin + NADP+ 1.1.1.235 8-oxocoformycin reductase
–
2-Octanone + NADPH + H+ <=> 2-Octanol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
3-phenylpropanal + NADPH + H+ <=> 3-Phenyl-1-propanol + NADP+ 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
5alpha-Androstan-17alpha-ol-3-one + NADP+ <=> 5alpha-Androstan-3,17-dione + NADPH + H+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
cholesterol + O2 + NADH + H+ <=> 7-dehydrocholesterol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
D-mannosamine + NADP+ <=> 2-amino-2-deoxy-D-mannono-1,5-lactone + NADPH 1.1.1.119 glucose 1-dehydrogenase (NADP+)
–
7-cyano-7-carbaguanine + 2 NADPH + 2 H+ <=> queuine + 2 NADP+ 1.7.1.13 preQ1 synthase
–
Tetradecanal + NADPH + H+ <=> Tetradecanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
2-aceto-2-hydroxybutyrate + NADP+ <=> 2R,3R-2,3-dihydroxy-3-methylpentanoate + NADPH + H+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
Benzene + NADPH + O2 <=> cis-benzene_dihydrodiol + NADP+ 1.14.12.3 benzene 1,2-dioxygenase
–
cis-benzene_dihydrodiol + NADP+ <=> 1,2-benzoquinone + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
L-sorbitol + NADP+ <=> L-sorbose + NADPH 1.1.1.10 L-xylulose reductase
1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.289 sorbose reductase
–
–
–
–
6-methylpterin + NADPH <=> 6-methyldihydropterin + NADP+ 1.5.1.3 dihydrofolate reductase
–
caffeoyl_aldehyde + NADP+ <=> dihydrocaffeoyl_aldehyde + NADPH + H+ 1.3.1.102 2-alkenal reductase (NADP+)
–
caffeoyl_aldehyde + NADP+ <=> caffeoyl_alcohol + NADPH + H+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
thymine + NADP+ <=> Dihydrothymine + NADPH + H+ 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
3,3,5-trimethylcyclohexanone + NADPH + H+ + O2 <=> 4,6,6-trimethyloxepan-2-one + 4,4,6-trimethyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
GDP-4-dehydro-6-deoxy-D-mannose + NADPH <=> GDP-fucose + NADP+ 1.1.1.271 GDP-L-fucose synthase
–
4-oxonon-2-enal + NADPH <=> 1-hydroxynonen-4-one + NADP+ 1.1.1.21 aldose reductase
–
lanosterol + NADPH <=> 24-dihydrolanosterol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
3-nitroacetophenone + NADPH <=> 1-(3-nitrophenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
4-hexanoylpyridine + NADPH + H+ <=> 1-(pyridin-4-yloxy)hexan-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
corticosterone + NADPH <=> corticosterol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
hexanophenone + NADPH <=> 1-phenylhexan-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
butyrophenone + NADPH <=> 1-phenylbutan-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
1,4-benzoquinone + NADP+ <=> hydroquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
ITP + NAD+ <=> IDP + NADP+ 2.7.1.23 NAD+ kinase
–
(24R)-cholest-5-ene-3beta,24-diol + NADPH + H+ + O2 <=> (24R)-cholest-5-ene-3beta,7alpha,24-triol + NADP+ + H2O 1.14.14.26 24-hydroxycholesterol 7alpha-hydroxylase
–
5alpha-dihydroprogesterone + NADPH + O2 <=> 5alpha-pregnan-17alpha-ol-3,20-dione + NADP+ + H2O 1.14.14.19 steroid 17alpha-monooxygenase
–
17alpha-hydroxyprogesterone + NADPH <=> 5alpha-pregnan-17alpha-ol-3,20-dione + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
Zn-7-hydroxy-Pheide_a + O2 + NADPH <=> Zn-pheophorbide_b + H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
peroxiredoxin_disulfide + NADPH <=> reduced_peroxiredoxin + NADP+ 1.8.1.8 protein-disulfide reductase
–
luteoforol + NADPH <=> luteoliflavan + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
–
eriodictyol + NADPH <=> luteoliflavan + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
–
2,5-dimethyl-4-benzoquinone + NADPH <=> 2,5-dimethyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
–
–
2-Octanone + NADPH + O2 <=> heptyl_acetate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
dibenzo-p-dioxin + NADPH + H+ + O2 <=> 2,2'',3-trihydroxybiphenyl_ether + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
19-nortestosterone + NADP+ <=> 4-estrene-3,17-dione + NADH 1.1.1.112 indanol dehydrogenase
–
19-nortestosterone + NADP+ <=> 4-estrene-3,17-dione + NADPH 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
trans-2-Butene + NADPH + O2 <=> trans-2,3-Epoxybutane + 2-Buten-1-ol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
2-Buten-1-al + NADPH <=> 2-Buten-1-ol + NADP+ 1.1.1.72 glycerol dehydrogenase (NADP+)
–
2-Hexanone + NADPH + H+ <=> 2-Hexanol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
tigloyl-CoA + NADPH <=> 2-methylbutanoyl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
fluorobenzene + NADPH + O2 <=> 4-Fluorophenol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
pregnenolone + NADPH + H+ <=> 5-Pregnene-3,20-dione + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
5beta-androstane-3alpha,17beta-diol + NADP+ <=> androsterone + NADPH 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
5beta-androstane-3alpha,17beta-diol + NADP+ <=> 5beta-androstane-3alpha-17-one + NADPH 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
crotonyl-[acyl-carrier_protein] + NADPH <=> butyryl-[acyl-carrier_protein] + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
–
–
(2E)-but-2-enoyl-[acyl_carrier_protein] + NADPH + H+ <=> butyryl-[acyl-carrier_protein] + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
L-glutamine + 2-oxoglutarate + reduced_ferredoxin + NADPH + H+ <=> L-glutamate + oxidized_ferredoxin + NADP+ 1.4.7.1 glutamate synthase (ferredoxin)
–
2-dehydro-L-gluconate + NADPH + H+ <=> L-Idonate + NADP+ 1.1.1.215 gluconate 2-dehydrogenase
–
L-threose + NADPH <=> L-Threitol + NADP+ 1.1.1.10 L-xylulose reductase
–
obtusifolione + NADPH <=> obtusifoliol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
Prostaglandin_A2 + NADP+ <=> 15-ketoprostaglandin_A2 + NADPH + H+ 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
–
17-hydroxy-pregn-4-ene-3,11,20,21-tetraone + NADPH + H+ <=> 17,21-dihydroxy-pregn-4-ene-3,11,20-trione + NADP+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
fluorene + NADPH + H+ + O2 <=> 9-fluorenone + 9-fluorenol + 9-fluorenol + fluorene_dihydrodiol + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
5alpha-dihydrotestosterone + NADPH <=> androstanedione + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
steroid + NADP+ <=> 3-keto_steroid + NADPH 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
methylamine + 2-oxobutyrate + NADPH <=> L-glutamate + H2O + NADP+ 1.4.1.17 N-methylalanine dehydrogenase
–
L-3-hydroxyisobutyrate + NADP+ <=> 2-Methyl-3-oxopropanoate + NADPH 1.1.1.276 serine 3-dehydrogenase (NADP+)
–
citral + NADPH <=> 3-phenylpropanal + NADP+ 1.3.1.31 2-enoate reductase
–
cinnamaldehyde + NADPH + H+ <=> 3-phenylpropanal + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
–
veratryl_alcohol + NADP+ <=> 3,4-dimethoxybenzaldehyde + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
2''-carboxy-4-N,N-dimethylazobenzene + NADH <=> anthranilate + N,N-dimethyl-1,4-phenylenediamine + NADP+ 1.7.1.6 azobenzene reductase
–
2''-carboxy-4-N,N-dimethylazobenzene + NADPH <=> anthranilate + N,N-dimethyl-1,4-phenylenediamine + NADP+ 1.7.1.17 FMN-dependent NADH-azoreductase
1.7.1.6 azobenzene reductase
–
–
6-phosphono-D-gluconate + NADP+ <=> D-ribulose_5-phosphate + CO2 + NADPH 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
–
6-phosphono-D-gluconate + NADP+ <=> 3-keto-6-phosphono-D-gluconate + NADPH 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
–
6-phosphono-D-gluconate + NADP+ <=> D-ribulose_5-phosphate + NADPH 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
–
6-phosphono-D-gluconate + NADP+ <=> 6-phospho-2-dehydro-D-gluconate + NADPH 1.1.1.43 phosphogluconate 2-dehydrogenase
–
hydroxy(oxo)(3,6,8-trinitro-9H-carbazol-1-yl)ammonium + NADPH_+ <=> 2-[nitro(2,4,6-trinitrophenyl)amino]ethyl_nitrate + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-[nitro(2,4,6-trinitrophenyl)amino]ethyl_nitrate + NADPH_+ <=> 2-[nitro(2,4,6-trinitrophenyl)amino]ethyl_nitrate + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
androsterone + NADP+ <=> 5alpha-Androstan-3,17-dione + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
pregnan-3,20-dione + NADPH <=> androsterone + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
4-androstene-3,17-dione + NADPH + H+ <=> androsterone + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
3-oxodecanoyl-CoA + NADPH <=> (3R)-3-hydroxydecanoyl-CoA + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
1.1.1.36 acetoacetyl-CoA reductase
–
–
11-oxo-progesterone + NADPH <=> 11beta-hydroxyprogesterone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
11-deoxycorticosterone + NADPH + O2 <=> 18-hydroxycorticosterone + NADP+ + H2O 1.14.15.4 steroid 11beta-monooxygenase
–
2,3-Dihydro-2,5-dihydroxy-4H-benzopyran-4-one + NADP+ <=> 4,5-Dihydroxy-2H-benzopyran-2-one + NADPH + H+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
2-dehydro-D-glucose + NADP+ <=> D-mannose + NADPH 1.1.1.263 1,5-anhydro-D-fructose reductase
–
D-serine + NADP+ <=> 2-ammoniomalonate_semialdehyde + NADPH 1.1.1.276 serine 3-dehydrogenase (NADP+)
–
6-deoxy-D-glucosone + NADP+ <=> 6-deoxy-D-mannose + NADPH 1.1.1.263 1,5-anhydro-D-fructose reductase
–
D-allosone + NADP+ <=> D-altrose + NADPH 1.1.1.263 1,5-anhydro-D-fructose reductase
–
3''-methoxyacetophenone + NADPH + H+ <=> 1-(3''-methoxyphenyl)ethanol + NADP+ 1.1.1.B4
–
4'-bromoacetophenone + NADPH <=> 1-(4-bromophenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
5alpha-dihydrotestosterone + NADPH <=> 5alpha-androstane-3alpha,17alpha-diol + NADP+ 1.1.1.148 estradiol 17alpha-dehydrogenase
–
6-deoxy-D-glucosone + NADPH + H+ <=> 6-deoxy-D-mannose + NADP+ 1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
–
N-methyl-4-pieridinone + NADPH <=> N-methyl-1-piperidinol + NADP+ 1.1.1.206 tropinone reductase I
–
N-Methyl-4-piperidone + NADPH <=> N-methyl-1-piperidinol + NADP+ 1.1.1.206 tropinone reductase I
–
(4aR,8aS)-8a-methylhexahydronaphthalene-1,6(2H,5H)-dione + NADPH + O2 <=> (5aR,9aS)-9a-methylhexahydrobenzo[b]oxepine-2,7-dione + (4aS,6S,8aR)-6-hydroxy-8a-methyloctahydronaphthalen-1-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
(1aS,4aS,8aS)-8a-methylhexahydronaphthalene-1,6-dione + NADPH + O2 <=> (5aR,9aS)-9a-methylhexahydrobenzo[b]oxepine-2,7-dione + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
DL-glyceraldehyde + NADPH <=> DL-glyceraldehyde + NADP+ 1.1.1.188 prostaglandin-F synthase
–
(+)-limonene + NADPH + O2 <=> perillyl_alcohol + NADP+ + H2O 1.14.14.52 (S)-limonene 7-monooxygenase
–
(-)-limonene + NADPH + O2 <=> perillyl_alcohol + NADP+ + H2O 1.14.14.52 (S)-limonene 7-monooxygenase
–
salicyl_alcohol + NADP+ <=> 4-hydroxybenzaldehyde + NADPH 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
vinorine + NADPH + H+ + O2 <=> Vomilenine + NADP+ + H2O 1.14.13.75 vinorine hydroxylase
–
formaldehyde + glutathione + NADP+ <=> S-formylglutathione + NADPH + H+ 1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase
–
glutathione-hydroxyethyl_disulfide + NADPH + H+ <=> glutathione + 2-sulfanylethan-1-ol + NADP+ 1.8.1.B1
–
protochlorophyllide_b + NADPH + H+ <=> chlorophyllide_b + NADP+ 1.3.1.33 protochlorophyllide reductase
–
D-mannitol + NADP+ <=> L-Fructose + NADPH + H+ 1.1.1.289 sorbose reductase
–
(2E,6E)-farnesyl_diphosphate + phythyl_diphoshate + NADPH + H+ <=> squalene + (6E,10E,14E)-2,6,10,15,19,23,27-heptamethyloctacosa-2,6,10,14-tetraene + lycopadiene + NADP+ 2.5.1.148 lycopaoctaene synthase
–
3-methyl-2-buten-1-ol + NADP+ <=> 3-methylbut-2-enal + NADPH 1.1.1.183 geraniol dehydrogenase (NADP+)
–
4-coumaraldehyde + NADP+ <=> 3-(4-hydroxyphenyl)-propanal + NADPH + H+ 1.3.1.102 2-alkenal reductase (NADP+)
–
2-oxoisovalerate + NADPH <=> 2-hydroxyvalerate + NADP+ 1.1.1.169 2-dehydropantoate 2-reductase
–
muconaldehyde + NADP+ + H2O <=> trans,trans-muconate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
–
2-hexylidene-cyclopentanone + NADPH + H+ <=> 2-n-hexylcyclopentanone + NADP+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
–
diketone + NADPH + O2 <=> (R)-1-acetoxy-phenylacetone + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
2,2,6-trimethylcyclohexanone + NADPH + H+ + O2 <=> 3,7,7-trimethyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
1alpha-hydroxyvitamin_D + NADPH + O2 <=> 1alpha,25-dihydroxyvitamin_D + NADP+ + H2O 1.14.15.18 calcidiol 1-monooxygenase
–
25-hydroxyvitamin_D3 + NADPH + O2 <=> 1alpha,25-dihydroxyvitamin_D + NADP+ + H2O 1.14.15.18 calcidiol 1-monooxygenase
–
cimetidine + NADPH + O2 <=> cimetidine_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
lanosterol + NADPH + O2 <=> 4,4-dimethylcholesta-8,14,24-trienol + NADP+ + H2O 1.14.14.154 sterol 14alpha-demethylase
–
2-oxoisoleucine + NADPH <=> 2-D-hydroxyisoleucine + NADP+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
–
2-phenylcyclohexanone + NADPH + O2 <=> 7-phenyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
geldanamycin + NADH + H+ <=> reduced_geldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
geldanamycin + NADPH + H+ <=> reduced_geldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
Met-Phe + NADPH + O2 <=> (L-Met-S-oxide)-Phe + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
Phe-Met + NADPH + O2 <=> (L-Met-S-oxide)-Phe + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2-methylcyclohexanone + NADPH + O2 + H+ <=> 7-methyloxepan-2-one + NADP+ + H2O 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
triiodophenol + NADPH + O2 <=> Diphenylhydantoin + I- + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
24-methylenelophenone + NADPH <=> 24(28)-methylene_lophenol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
4-chloroacetophenone + NADP+ <=> 4-chloroacetophenone + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
5beta-pregnane-3alpha,20alpha-diol + NADPH + H+ <=> 5beta-pregnane-20alpha-ol-3-one + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
artemisinic_alcohol + O2 + NADPH + H+ <=> artemisinic_aldehyde + NADP+ + 2 H2O 1.14.13.158 amorpha-4,11-diene 12-monooxygenase
–
5''-hydroxyaverantin + NADP+ <=> (1''S)-5''-oxoaverantin + NADPH + H+ 1.2.1.B8
–
5''-hydroxyaverantin + NADP+ <=> 5''-oxoaverantin + NADPH + H+ 1.1.1.352 5'-hydroxyaverantin dehydrogenase
–
Polyphosphate + NAD+ <=> (Phosphate)n-1 + NADP+ 2.7.1.23 NAD+ kinase
–
progesterone + NADPH + O2 <=> 11alpha-hydroxyprogesterone + NADP+ + H2O 1.14.99.14 progesterone 11alpha-monooxygenase
–
2,4-Dihydroxybenzoate + NADPH + O2 <=> 2,3,4-Trihydroxybenzoate + 2,4,5-Trihydroxybenzoate + NADP+ + H2O 1.14.13.2 4-hydroxybenzoate 3-monooxygenase
–
1-(3''-carboxyphenylazo)-2-naphthol + NADPH <=> 3-aminobenzoic_acid + NADP+ + 1-amino-2-hydroxynaphthalene 1.7.1.6 azobenzene reductase
–
2-acetolactate + NADPH + H+ <=> 3-hydroxy-2-oxobutanoate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
D-glycerate + NADP+ <=> glyoxylate + NADPH + H+ 1.1.1.79 glyoxylate reductase (NADP+)
–
dihydrocarvone + NADPH + H+ + O2 <=> 4-isopropenyl-7-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
5beta-dihydrotestosterone + NADPH <=> 5beta-Androstan-3alpha,17beta-diol + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
–
5beta-Androstan-3alpha,17beta-diol + NADP+ <=> 5beta-androstane-3,17-dione + NADPH 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
quinonoid_2-amino-4-hydroxy-6,7-dimethyldihydropteridine + NADPH <=> 6,7-dimethyltetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
6,7-dimethyldihydropterin + NADPH + H+ <=> 6,7-dimethyltetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
pregnenolone + NADP+ <=> progesterone + NADPH + H+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
pregnenolone + NADP+ <=> 5-Pregnene-3,20-dione + NADPH 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
stearoyl-CoA + NADP+ <=> octadecanal + CoA + NADPH 1.2.1.50 long-chain acyl-protein thioester reductase
–
trans-2,3-dehydrostearoyl-CoA + NADPH <=> stearoyl-CoA + NADP+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
–
2-octadecenoyl-CoA + NADPH <=> stearoyl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
Arginine_methyl_ester + NADP+ <=> nicotinamide + N2-(2''-phospho-ADP-D-ribosyl)-L-arginine 2.4.2.31 NAD+---protein-arginine ADP-ribosyltransferase
–
24-methylene_cholesterol + NADPH + H+ <=> campesterol + ergosta-5-enol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
progesterone + 2 NADPH + 2 H+ + 2 O2 <=> 4-androstene-3,17-dione + acetate + 2 NADP+ + 2 H2O 1.14.14.19 steroid 17alpha-monooxygenase
–
D-gulose + NADP+ <=> D-gulono-1,5-lactone + NADPH 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
4-coumarylaldehyde + NADPH + H+ <=> p-coumaryl_alcohol + NADP+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
pentalenolactone_F + O2 + NADPH + H+ <=> pentalenolactone + NADP+ + H2O 1.14.19.8 pentalenolactone synthase
–
N10-formyltetrahydropteroylglutamate + NADPH + H+ <=> 10-formyltetrahydrofolate + NADP+ 1.5.1.3 dihydrofolate reductase
–
2,2,2-trifluoroacetophenone + NADPH + H+ <=> (S)-1-phenyl-2,2,2-trifluoroethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
quinonoid_7,8(6H)-dihydropterin + NADPH + H+ <=> Tetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
quinonoid_dihydrobiopterin + NADPH <=> Tetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
trans-2-decenoyl-CoA + NADH <=> decanoyl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
cis-2-decenoyl-CoA + NADPH + H+ <=> decanoyl-CoA + NADP+ 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH)
–
benzylidene_acetone + NADPH <=> benzylacetone + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
2-Hexanone + NADPH + O2 <=> butyl_acetate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
dTTP + NAD+ <=> dTDP + NADP+ 2.7.1.23 NAD+ kinase
–
N-[2-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-pyridinyl]-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide + NADPH + H+ <=> trans-4-hydroxy-L-proline + NADP+ 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]
–
D-1-pyrroline-4-hydroxy-2-carboxylate + NADPH + H+ <=> trans-4-hydroxy-L-proline + NADP+ 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]
1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
–
–
NADPH + H+ + Ubiquinone-10 <=> NADP+ + ubiquinol-10 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.8.1.4 dihydrolipoyl dehydrogenase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
stearoyl-[acyl-carrier_protein] + NADPH <=> hexadecanol + [acyl-carrier_protein] + NADP+ 1.2.1.50 long-chain acyl-protein thioester reductase
–
oleoyl-[acyl-carrier_protein] + NADPH + H+ <=> cis-9-octadecenal + [acyl-carrier_protein] + NADP+ 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
–
palmitoyl-[acyl-carrier_protein] + NADPH + H+ <=> octadecanal + [acyl-carrier_protein] + NADP+ 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
–
2-bromoacrylate + NADPH + H+ <=> (S)-2-bromopropionic_acid + NADP+ 1.3.1.103 2-haloacrylate reductase
–
1-Butaneboronate + NADPH + O2 <=> 1-butanol + BO33- + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
n-butane + NADPH + O2 <=> 1-butanol + 2-butanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
n-butane + NADPH + H+ + O2 <=> 1-butanol + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
Itaconate + NADPH <=> (2R)-2-methylbutanedioic_acid + NADP+ 1.3.1.31 2-enoate reductase
–
citraconate + NADPH <=> (2R)-2-methylbutanedioic_acid + NADP+ 1.3.1.31 2-enoate reductase
1.3.1.42 12-oxophytodienoate reductase
–
–
2-methylcyclopent-2-en-1-one + NADPH <=> (2S)-2-methylcyclopentanone + NADP+ 1.3.1.42 12-oxophytodienoate reductase
–
3-methylcyclopent-2-en-1-one + NADPH <=> (3S)-3-methylcyclopentanone + NADP+ 1.3.1.42 12-oxophytodienoate reductase
–
citral + NADPH <=> (3S)-3,7-dimethyloct-6-enal + NADP+ 1.3.1.42 12-oxophytodienoate reductase
–
[(E)-1-methyl-2-nitroethenyl]benzene + NADPH <=> [(1R)-1-methyl-2-nitroethyl]benzene + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
1.3.1.42 12-oxophytodienoate reductase
–
–
[(1Z)-1-nitroprop-1-en-2-yl]benzene + NADPH + H+ <=> [(1S)-1-methyl-2-nitroethyl]benzene + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
–
[(E)-1-methyl-2-nitroethenyl]benzene + NADPH <=> [(1S)-1-methyl-2-nitroethyl]benzene + NADP+ 1.3.1.31 2-enoate reductase
1.3.1.42 12-oxophytodienoate reductase
–
–
2-deoxy-6-phosphono-D-gluconate + NADP+ <=> 2-deoxy-3-oxo-6-phosphogluconate + NADPH 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
–
2 tibolone + 2 NADPH + 2 H+ <=> 3alpha-tibolone + 3beta-hydroxytibolone + 2 NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
5alpha-dihydroprogesterone + NADPH <=> 4-pregnen-3alpha,20beta-diol + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
nitrofurazone + NADPH + 4 H+ <=> 5-(hydroxyamino)furan-2-carbaldehyde_semicarbazone + NADP+ + H2O 1.5.1.30 flavin reductase (NADPH)
1.7.1.B3
–
–
reduced_nitrofurazone + 2 NADPH + 2 H+ <=> 5-(hydroxyamino)furan-2-carbaldehyde_semicarbazone + 2 NADP+ 1.7.1.16 nitrobenzene nitroreductase
–
(+)-epi-isozizaene + NADPH + H+ + O2 <=> (5R,S)-albaflavenol + NADP+ + H2O 1.14.13.106 epi-isozizaene 5-monooxygenase
–
D-arabinose + NADP+ <=> D-arabitol + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
D-arabinose + NADP+ <=> D-arabino-1,5-lactone + NADPH + H+ 1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
–
beta-amyrin + O2 + NADPH + H+ <=> erythrodiol + NADP+ + H2O 1.14.14.126 beta-amyrin 28-monooxygenase
–
1-formylpyrene + NADP+ + H2O <=> pyrene-1-carboxylic_acid + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
2-formylpyrene + NADP+ + H2O <=> pyrene-2-carboxylic_acid + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
4-formylpyrene + NADP+ + H2O <=> pyrene-4-carboxylic_acid + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
1-formyl-6-methylpyrene + NADP+ + H2O <=> 6-methylpyrene-1-carboxylic_acid + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
1-formyl-8-methylpyrene + NADP+ + H2O <=> 8-methylpyrene-1-carboxylic_acid + NADPH + H+ 1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
L-aspartate_4-semialdehyde + cacodylate + NADP+ <=> L-4-aspartyl_cacodylate + NADPH 1.2.1.11 aspartate-semialdehyde dehydrogenase
–
alpha-acetylphenylacetonitrile + NADPH + H+ + O2 <=> (R)-2-acetoxyphenylacetonitrile + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
1-(4-fluorophenyl)ethanol + NADP+ <=> 1-(4-fluorophenyl)ethanol + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
3-oxopentanoyl-CoA + NADPH <=> 3-hydroxyvaleryl-CoA + NADP+ 1.1.1.36 acetoacetyl-CoA reductase
–
4-androstene-3,17-dione + NADPH <=> 4-androsten-3alpha-ol-17-one + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
2,2,2-trifluoroacetophenone + NADPH + H+ <=> (1R)-2,2,2-trifluoro-1-phenylethanol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
–
–
2''-methylacetophenone + NADPH + H+ <=> 1-(2''-methyl)phenylethanol + NADP+ 1.1.1.B4
–
2 4-fluoroacetophenone + 2 NADPH + 2 H+ <=> (1S)-1-(4-fluorophenyl)ethanol + (1R)-1-(4-fluorophenyl)ethanol + 2 NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Pro-Thr-Val-Thr-Gly-Cys-S-S-selenoCys-Gly + NADPH + H+ <=> Pro-Thr-Val-Thr-Gly-Cys + selenoCys-Gly + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
NADPH + hydroxycobalamin <=> NADP+ + 5''-deoxyadenosylcobalamin 1.16.1.3 aquacobalamin reductase
–
4-hydroxyquinoline + NADPH + O2 <=> 1H-3-Hydroxy-4-oxoquinoline + NADP+ + H2O 1.14.13.62 4-hydroxyquinoline 3-monooxygenase
–
6-Hydroxymethylpterin + NADPH <=> 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + NADP+ 1.5.1.3 dihydrofolate reductase
–
2-Ethylphenol + NADPH + O2 <=> 3-ethylcatechol + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
6-oxohexanoate + NADP+ + H2O <=> Glutarate + NADPH 1.2.1.26 2,5-dioxovalerate dehydrogenase
–
D-tagaturonate + NADPH + H+ <=> D-altronate + NADP+ 1.1.1.58 tagaturonate reductase
–
3-methyl-2-oxopentanoate + NH3 + NADPH + H+ <=> D-isoleucine + H2O + NADP+ 1.4.99.6 D-arginine dehydrogenase
–
dITP + NAD+ <=> dIDP + NADP+ 2.7.1.23 NAD+ kinase
–
fecosterone + NADPH + H+ <=> fecosterol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH <=> fecosterol + NADP+ 1.3.1.70 Delta14-sterol reductase
–
Nogalamycin + NADP+ <=> 7-deoxynogalarol + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
glyoxylate + methylamine + NADPH + H+ <=> sarcosine + NADP+ 1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
trans-trans-2,4-hexadecadienoyl-CoA + NADPH <=> trans-2-hexadecenoyl-CoA + NADP+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
B
17alpha-estradiol-16-one + NADPH <=> 17-epiestriol + NADP+ 1.1.1.147 16alpha-hydroxysteroid dehydrogenase
–
biliverdin_IXbeta + NADPH + H+ <=> bilirubin + NADP+ 1.3.1.24 biliverdin reductase
–
2,4,6-trinitrotoluene + 2 NADPH + 2 H+ <=> N-hydroxy-2-methyl-3,5-dinitroaniline + 2 NADP+ + H2O 1.7.1.B1
–
all-trans-3-hydroxyretinal + NADPH + H+ <=> all-trans-3-hydroxyretinol + NADP+ 1.1.1.300 NADP-retinol dehydrogenase
–
5beta-pregnane-3,20-dione + NADPH + H+ <=> 5alpha-pregnan-20alpha-ol-3-one + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
20alpha-hydroxyprogesterone + NADPH <=> 5alpha-pregnan-20alpha-ol-3-one + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
potassium_ferricyanide + NADPH + H+ <=> potassium_ferrocyanide + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
GTP + NAD+ <=> GDP + NADP+ 2.7.1.23 NAD+ kinase
–
2,6-dichlorophenol + NADPH + O2 <=> 2,6-dichlorohydroquinone + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
3,5-dichlorophenol + NADPH + H+ + O2 <=> 2,6-dichlorohydroquinone + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
insulin_disulfide + NADPH + H+ <=> Insulin + NADP+ 1.8.1.B1
–
oxidized_cytochrome_c + NADPH + O2 <=> ferricytochrome_c + NADP+ + H2O 1.14.13.39 nitric-oxide synthase (NADPH)
–
cytochrome_c + NADPH + O2 <=> ferricytochrome_c + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
NADPH + oxidized_cytochrome_c <=> NADP+ + ferricytochrome_c 1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.3 ferredoxin---NAD+ reductase
1.18.1.7 ferredoxin---NAD(P)+ reductase (naphthalene dioxygenase ferredoxin-specific)
1.19.1.1 flavodoxin---NADP+ reductase
1.6.2.4 NADPH---hemoprotein reductase
1.7.1.6 azobenzene reductase
–
–
–
–
–
–
NADPH + electron_acceptor + H2O <=> NADP+ + reduced_electron_acceptor 1.17.1.4 xanthine dehydrogenase
–
2-decanone + NADPH + O2 <=> methyl_nonanoate + octyl_acetate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
oxidized_rubredoxin + NADP+ <=> reduced_rubredoxin + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
17beta-estradiol + NADPH <=> estrone + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
prostaglandin_H2 + NADP+ <=> prostaglandin_F2alpha + NADPH + H+ 1.1.1.188 prostaglandin-F synthase
–
reduced_dithiothreitol + NADP+ <=> oxidized_dithiothreitol + NADPH + H+ 1.8.4.2 protein-disulfide reductase (glutathione)
–
4-methylacetophenone + NADP+ <=> 1-(4-methylphenyl)ethanol + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
benzyl_ethyl_sulfide + NADPH + H+ + O2 <=> benzyl_ethyl_sulfide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
NADPH + H+ + phenyl-1,4-benzoquinone <=> NADP+ + biphenyl-2,5-diol 1.6.5.10 NADPH dehydrogenase (quinone)
–
2-carboxybenzaldehyde + NADPH <=> salicylate + NADP+ 1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
–
Styrene + O2 + NADPH <=> (R)-styrene_oxide + (S)-styrene_oxide + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
DL-glyceraldehyde + NADPH <=> dihydroxyacetone + NADP+ 1.1.1.10 L-xylulose reductase
–
thioredoxin_2 + NADP+ <=> thioredoxin_2_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
D-sorbitol + NADP+ <=> D-sorbose + NADPH + H+ 1.1.1.10 L-xylulose reductase
1.1.1.138 mannitol 2-dehydrogenase (NADP+)
–
–
D-sorbitol + NADP+ <=> sorbose + NADPH 1.1.1.287 D-arabinitol dehydrogenase (NADP+)
–
thioredoxin_disulfide_41 + NADPH + H+ <=> thioredoxin_41 + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin_41 + NADP+ <=> thioredoxin_41_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin_disulfide_8 + NADPH + H+ <=> thioredoxin_8 + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin_8 + NADP+ <=> thioredoxin_8_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
hexanal + NADPH + H+ <=> hexanal + NADP+ 1.1.1.1 alcohol dehydrogenase
–
11-cis-retinol-[cellular_retinaldehyde_binding_protein] + NADP+ <=> 11-cis-retinal-[cellular_retinaldehyde_binding_protein] + NADPH + H+ 1.1.1.315 11-cis-retinol dehydrogenase
–
protein-disulfide_isomerase + NADPH <=> protein-disulfide_isomerase + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
oxidized_3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium_bromide + NADPH <=> 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazolium_bromide + NADP+ 1.6.2.4 NADPH---hemoprotein reductase
1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
–
thioredoxin-R + NADP+ <=> thioredoxin-R_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
all-trans-retinol-[cellular-retinol-binding-protein] + NADP+ <=> all-trans-retinal-[cellular-retinol-binding-protein] + NADPH + H+ 1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
–
NADPH + H+ + menadione <=> NADP+ + reduced_menadiol 1.6.5.10 NADPH dehydrogenase (quinone)
–
3-oxooctanoyl-CoA + NADPH <=> (R)-3-hydroxyoctanoyl-CoA + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
2-aminocyclohexanol + NADP+ <=> 2-aminocyclohexanone + NADPH + H+ 1.1.1.75 (R)-aminopropanol dehydrogenase
–
1,2-naphthoquinone + NADPH + H+ <=> 1,2-naphthosemiquinone + NADP+ 1.6.5.5 NADPH:quinone reductase
–
1-bromo-indanone + NADPH + O2 <=> 6-bromoisochroman-1-one + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
1-Indanone + NADPH + O2 <=> 3-isochromanone + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
alpha-tetralone + NADPH + H+ + O2 <=> 4,5-dihydro-1-benzoxepin-2(3H)-one + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
2 9,10-phenanthrenequinone + NADPH + H+ <=> 2 9,10-phenanthrenesemiquinone + NADP+ 1.6.5.5 NADPH:quinone reductase
–
2 5-hydroxy-1,4-naphthoquinone + NADPH + H+ <=> 2 5-hydroxy-1,4-naphthosemiquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
–
–
(2E,4E)-hexa-2,4-dienal + NADPH <=> trans-4-hexenal + NADP+ 1.3.1.27 2-hexadecenal reductase
–
NADPH + K3Fe(CN)6 <=> NADP+ + reduced_K3Fe(CN)6 1.18.1.2 ferredoxin---NADP+ reductase
–
retinol_bound_to_cellular_retinol_binding_protein + NADP+ <=> retinal_bound_to_cellular_retinol_binding_protein + NADPH 1.1.1.300 NADP-retinol dehydrogenase
–
propane + NADPH + O2 <=> 1-propanol + 2-propanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
(S)-scoulerine + NADPH + H+ + O2 <=> (S)-cheilanthifoline + NADP+ + 2 H2O 1.14.21.2 (S)-cheilanthifoline synthase
–
(S)-cheilanthifoline + NADPH + H+ + O2 <=> (S)-Stylopine + NADP+ + 2 H2O 1.14.21.1 (S)-stylopine synthase
–
propane + NADPH + H+ + O2 <=> 1-propanol + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
2-aceto-2-hydroxybutyrate + NADPH <=> 2,3-dihydroxy-3-methylpentanoate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
B
3-Hydroxy-3-methyl-2-oxopentanoate + NADPH + H+ <=> 2,3-dihydroxy-3-methylpentanoate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
2-Heptanol + NADP+ <=> 2-Heptanone + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
2-methylcyclohexyl_boronic_acid + NADPH + O2 <=> 2-Methylcyclohexanol + BO33- + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
2-methylcyclohexanone + NADPH <=> 2-Methylcyclohexanol + NADP+ 1.1.1.236 tropinone reductase II
–
3-Hexanol + NADP+ <=> hexan-3-one + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
–
3-Hydroxy-5-methylbenzoate + NADPH + O2 <=> 3-Methylgentisate + NADP+ + H2O 1.14.13.24 3-hydroxybenzoate 6-monooxygenase
–
3-hydroxy-3-methylbenzoate + NADPH + O2 <=> 3-Methylgentisate + NADP+ + H2O 1.14.13.24 3-hydroxybenzoate 6-monooxygenase
–
4-cyanobenzaldehyde + NADP+ + H2O <=> 4-Cyanobenzoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
–
4-Heptanone + NADPH + H+ <=> 4-heptanol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
oxaloacetate + NADP+ <=> pyruvate + CO2 + NADPH 1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
–
4-Methyl-1-pentanol + NADP+ <=> 4-Methylpentanal + NADPH 1.1.1.80 isopropanol dehydrogenase (NADP+)
–
uracil47_in_tRNA + NADPH + H+ <=> 5,6-dihydrouracil20_in_tRNA + NADP+ 1.3.1.89 tRNA-dihydrouridine47 synthase [NAD(P)+]
–
uracil20a_in_tRNA + NADPH + H+ <=> 5,6-dihydrouracil20b_in_tRNA + NADP+ 1.3.1.90 tRNA-dihydrouridine20a/20b synthase [NAD(P)+]
–
NADPH + H+ + polysulfide(n) <=> NADP+ + polysulfide(n-1) 1.12.98.4 sulfhydrogenase
–
thioredoxin_3 + NADP+ <=> thioredoxin_3_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
2 Fe(II)-siderophore + NADP+ + H+ <=> 2 Fe(III)-siderophore + NADPH 1.16.1.10 ferric-chelate reductase [NAD(P)H]
1.16.1.9 ferric-chelate reductase (NADPH)
–
–
chenodeoxycholoyl-CoA + NADP+ <=> 3-oxochenodeoxycholoyl-CoA + NADPH + H+ 1.1.1.395 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase
–
5-Keto-D-fructose_1-phosphate + NADPH + H+ <=> D-Fructose_1-phosphate + NADP+ 1.1.1.124 fructose 5-dehydrogenase (NADP+)
–
thioredoxin_C-2 + NADP+ <=> thioredoxin_C-2_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
NAD+ + Tetrapolyphosphate <=> NADP+ + poly(P)3 2.7.1.23 NAD+ kinase
–
o-Cresol + NADPH + O2 <=> 3-methylcatechol + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
3-methyl-2-nitrophenol + NADPH + O2 <=> 3-methylcatechol + NADP+ + H2O 1.14.13.31 2-nitrophenol 2-monooxygenase
–
Orange_G + 2 NADPH + 2 H+ <=> aniline + 8-amino-7-hydroxynaphthalene-1,3-disulfonic_acid + 2 NADP+ 1.7.1.17 FMN-dependent NADH-azoreductase
–
1-phenylazo-2-hydroxy-6-sulfonaphthalene + NADPH <=> aniline + NADP+ + 1-amino-2-hydroxy-6-sulfonaphthalene 1.7.1.6 azobenzene reductase
–
1-phenylazo-2-hydroxy-6-carboxynaphthalene + NADPH <=> aniline + NADP+ + 1-amino-2-hydroxy-6-carboxynaphthalene 1.7.1.6 azobenzene reductase
–
4-nitrophenyl + 2 NADPH + 2 H+ <=> aniline + 2 NADP+ + H2O 1.7.1.16 nitrobenzene nitroreductase
–
stearoyl-CoA + NADPH + H+ <=> octadecanol + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
succinate + NADP+ <=> Succinic_anhydride + NADPH 1.1.1.48 D-galactose 1-dehydrogenase
–
protein_disulfide_isomerase_like_protein_1 + NADPH <=> protein_disulfide_isomerase_like_protein_1 + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
protein_disulfide_isomerase_like_protein_2 + NADPH <=> protein_disulfide_isomerase_like_protein_2 + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
rat_thioredoxin + NADP+ <=> rat_thioredoxin_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin_K36E + NADP+ <=> thioredoxin_K36E_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin_K36R + NADP+ <=> thioredoxin_K36R_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin_P34S + NADP+ <=> thioredoxin_P34S_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin-CAC + NADP+ <=> thioredoxin-CAC_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
thioredoxin-II + NADP+ <=> thioredoxin-II_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
4-hydroxy-5-methyl-2-methylene-3(2H)-furanone + NADPH + H+ <=> (2R)-4-hydroxy-2,5-dimethyl-3(2H)-furanone + NADP+ 1.3.1.105 2-methylene-furan-3-one reductase
–
taurolithocholate + NADP+ <=> 2[[7alpha,12alpha-Dihydroxy-3,24-dioxo-5beta-cholan-24-yl]amino]ethane_sulfonic_acid + NADPH 1.1.1.112 indanol dehydrogenase
–
tetrafluoro-1,4-benzoquinone + NADPH <=> tetrachlorohydroquinone + NADP+ 1.1.1.404 tetrachlorobenzoquinone reductase
1.14.13.50 pentachlorophenol monooxygenase
–
–
propane + NADPH + H+ + O2 <=> 2-propanol + NADP+ + H2O 1.14.13.227 propane 2-monooxygenase
–
diacetyl + NADPH + H+ <=> (S)-acetoin + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.304 diacetyl reductase [(S)-acetoin forming]
–
–
K3[Fe(CN)6] + NADPH <=> K4[Fe(CN)6] + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
L-Glycerate + NADP+ <=> tartronate_semialdehyde + NADPH + H+ 1.1.1.60 2-hydroxy-3-oxopropionate reductase
–
peroxiredoxin + NADPH + H+ <=> peroxiredoxin_disulfide + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
ZnPheide_a + O2 + NADPH <=> Zn-7-hydroxy-Pheide_a + H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
L-norvaline + H2O + NADP+ <=> 2-Oxopentanoate + NH3 + NADPH 1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
–
–
(R)-pulegone + NADP+ <=> (+)-isomenthone + (-)-menthone + NADPH + H+ 1.1.1.54 allyl-alcohol dehydrogenase
–
(R)-pulegone + NADP+ <=> (+)-isomenthone + NADPH + H+ 1.1.1.54 allyl-alcohol dehydrogenase
–
5beta-androstane-3beta,17beta-diol + NADP+ <=> epiandrosterone + NADPH 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NADP+ <=> 2,3-Dihydroxybiphenyl + NADPH 1.3.1.56 cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
–
Cyclohex-1-enecarbaldehyde + NADPH + H+ <=> cyclohexanal + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
–
D-glucosamine + NADP+ <=> D-glucosamino-1,5-lactone + NADPH 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
1-(3''-phosphophenylazo)-2-naphthol + NADPH <=> 3-amino-1-benzenephosphate + NADP+ + 1-amino-2-hydroxynaphthalene 1.7.1.6 azobenzene reductase
–
1-(3''-sulfophenylazo)-2-naphthol + NADPH <=> 3-amino-1-benzenesulfonic_acid + NADP+ + 1-amino-2-hydroxynaphthalene 1.7.1.6 azobenzene reductase
–
1-(4''-phosphophenylazo)-2-naphthol + NADPH <=> 4-amino-1-benzenephosphate + NADP+ + 1-amino-2-hydroxynaphthalene 1.7.1.6 azobenzene reductase
–
1-(2''-methyl-4''-sulfophenylazo)2-naphthol + NADPH <=> 4-amino-2-methyl-1-benzenesulfonic_acid + NADP+ + 1-amino-2-hydroxynaphthalene 1.7.1.6 azobenzene reductase
–
4-[(2-hydroxy-1-naphthalenyl)azo]benzene_sulfonic_acid + NADPH <=> Sulfanilic_acid + NADP+ + 1-amino-2-hydroxynaphthalene 1.7.1.6 azobenzene reductase
–
2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NADPH + H+ + O2 <=> 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NADP+ + H2O 1.14.14.110 2-hydroxy-1,4-benzoxazin-3-one monooxygenase
–
Escherichia_coli_thioredoxin_disulfide + NADPH + H+ <=> Escherichia_coli_thioredoxin + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
5beta-Pregnan-3alpha-ol-20-one + NADPH + H+ <=> 5alpha-pregnane-3alpha,20alpha-diol + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
prostaglandin_H2 + NADPH + H+ <=> 9alpha,11beta-prostaglandin_F2 + NADP+ 1.1.1.188 prostaglandin-F synthase
–
fluoranthene + NADPH + H+ + O2 <=> cis-2,3-dihydroxy-2,3-dihydrofluoranthene + monohydroxyfluoranthene + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
fluoranthene + NADPH + H+ + O2 <=> cis-2,3-dihydroxy-2,3-dihydrofluoranthene + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
narbomycin + 2 NADPH + 2 H+ + 2 O2 <=> novapikromyin + 2 NADP+ + 2 H2O 1.14.13.185 pikromycin synthase
–
L-fuconolactone + NADPH + H+ <=> L-fucose + NADP+ 1.1.1.122 D-threo-aldose 1-dehydrogenase
1.1.1.B35
–
–
L-fucose + NADP+ <=> 6-deoxy-L-galactono-1,4-lactone + NADPH + H+ 1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.B35
–
–
lauroyl-CoA + NADP+ <=> dodecanal + CoA + NADPH 1.2.1.50 long-chain acyl-protein thioester reductase
–
cis-2-dodecenoyl-CoA + NADPH + H+ <=> lauroyl-CoA + NADP+ 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH)
–
dodec-2-enoyl-CoA + NADPH + H+ <=> lauroyl-CoA + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
4-methyl-2-oxopentanoate + NADPH + H+ <=> 2-hydroxyisocaproate + NADP+ 1.1.1.79 glyoxylate reductase (NADP+)
–
4,4''-diapolycopenedial + NADP+ <=> 4,4''-diapolycopen-4''-al-4-oic_acid + NADPH + H+ 1.2.1.B23
–
1alpha,25-dihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 24-oxo-1,23,25-trihydroxyvitamin_D3 + 24,25,26,27-tetranor-1,23-dihydroxyvitamin_D3 + 1alpha,24R,25-trihydroxyvitamin_D3 + 24-oxo-1,25-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
1alpha,25-dihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,24R,25-trihydroxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
(3R)-hydroxyhexadecanoyl-CoA + NADP+ <=> 3-ketohexadecanoyl-CoA + NADPH + H+ 1.1.1.36 acetoacetyl-CoA reductase
–
Coproporphyrinogen-III + 2 NADP+ <=> protoporphyrinogen-IX + 2 CO2 + 2 NADPH + 2 H+ 1.3.3.3 coproporphyrinogen oxidase
–
rac-3-methyl-4-phenylbutan-2-one + NADPH + H+ + O2 <=> (2R)-1-phenylpropan-2-yl_acetate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
dATP + NAD+ <=> dADP + NADP+ 2.7.1.23 NAD+ kinase
–
[protein_disulfide_oxidoreductase]-dithiol + NADP+ <=> [protein_disulfide_oxidoreductase]-disulfide + NADPH + H+ 1.8.1.B4
–
D-carnitine + NADPH + H+ + O2 <=> (3S)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O 1.14.13.239 carnitine monooxygenase
–
trimethylamine + H2O + NADP+ <=> Dimethylamine + formaldehyde + NADPH 1.5.8.2 trimethylamine dehydrogenase
–
(R)-mandelate + NADP+ <=> benzoylformate + NADPH + H+ 1.1.1.B65
–
3,4-dihydroxybenzoate + NADP+ + H2O <=> 2-Pyrone-4,6-dicarboxylate + NADPH + H+ 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
–
5alpha-dihydrotestosterone + NADP+ <=> 5alpha-17-oxo-dihydrotestosterone + NADH 1.1.1.112 indanol dehydrogenase
–
Boc-Gly-Lys-Arg-4-methylcoumarin_7-amide + NADPH <=> 5alpha-dihydrotestosterone + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
5alpha-dihydrotestosterone + NADP+ <=> 5alpha-Androstan-3,17-dione + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
5alpha-androstane-3alpha,17beta-diol + NADPH <=> 5alpha-dihydrotestosterone + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
–
–
5alpha-dihydrotestosterone + NADP+ <=> 5alpha-17-oxo-dihydrotestosterone + NADPH 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
5-androstene-3,17-dione + NADPH <=> 5alpha-dihydrotestosterone + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
Tetrapolyphosphate + NAD+ <=> tripolyphosphate + NADP+ 2.7.1.23 NAD+ kinase
–
galactoflavin + NADPH <=> reduced_galactoflavin + NADP+ 1.5.1.30 flavin reductase (NADPH)
–
2,4-dihydroxybutanal + NADPH + H+ <=> 1,2,4-butanetriol + NADP+ 1.1.1.72 glycerol dehydrogenase (NADP+)
–
artemisinic_aldehyde + O2 + NADPH + H+ <=> artemisinate + NADP+ + H2O 1.14.13.158 amorpha-4,11-diene 12-monooxygenase
–
amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+ <=> artemisinate + 3 NADP+ + 4 H2O 1.14.13.158 amorpha-4,11-diene 12-monooxygenase
–
3-Hydroxy-2-methylpyridine-5-carboxylate + NADH + O2 <=> 2-(Acetamidomethylene)succinate + NADP+ 1.14.13.242 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase
–
17alpha-hydroxyprogesterone + NADPH + O2 <=> corticosteroids + NADP+ + H2O 1.14.14.16 steroid 21-monooxygenase
–
ubiquinone + NADH <=> ubiquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2 2-xylene + 2 NADPH + 2 H+ + 2 O2 <=> 2,3-dimethylphenol + 3,4-dimethylphenol + 2 NADP+ + 2 H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
Dimethylamine + NADPH + O2 <=> secondary_nitrone + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
3-Heptanone + NADPH <=> 3-Heptanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
3-Hydroxy-4-methoxybenzaldehyde + NADP+ + H2O <=> Isovanillate + NADPH 1.2.1.67 vanillin dehydrogenase
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
–
–
3-methylcyclohexanone + NADP+ <=> 3-Methylcyclohexanol + NADP+ 1.1.1.206 tropinone reductase I
–
NADPH + ferrimyoglobin <=> NADP+ + ferromyoglobin 1.6.2.6 leghemoglobin reductase
–
oxidized_cytochrome_c + NADPH <=> reduced_cytchrome_c + NADP+ 1.12.1.2 hydrogen dehydrogenase
–
6,7-dimethyl-5,6,7,8-tetrahydrobiopterin + NADP+ <=> 6,7-dimethyl-7,8-dihydrobiopterin + NADPH + H+ 1.5.1.34 6,7-dihydropteridine reductase
–
CMP-N-acetylneuraminate + NADPH + O2 <=> CMP-N-glycoloylneuraminate + NADP+ + H2O 1.14.18.2 CMP-N-acetylneuraminate monooxygenase
–
D-Idose + NADP+ <=> D-idono-1,5-lactone + NADPH 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
cyclo(L-tyrosyl-L-tyrosyl) + NADPH + H+ + O2 <=> mycocyclosin + NADP+ + 2 H2O 1.14.21.9 mycocyclosin synthase
–
3,4-dihydroxybenzoate + NADPH + H+ + O2 <=> gallic_acid + NADP+ + H2O 1.14.13.2 4-hydroxybenzoate 3-monooxygenase
–
L-glutamate_5-semialdehyde + NADP+ + H2O <=> L-glutamate + NADPH + H+ 1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
–
(15Z)-tetracosenoyl-CoA + NADPH <=> lignoceroyl-CoA + NADP+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
–
4,4''-diapolycopen-4''-al-4-oic_acid + NADP+ <=> 4,4''-diapolycopen-4,4''-dioic_acid + NADPH + H+ 1.2.1.B23
–
oxidized_insulin + NADPH + H+ <=> reduced_insulin + NADP+ 1.8.1.B1
–
Maleic_anhydride + NADPH <=> Succinic_anhydride + NADP+ 1.3.1.31 2-enoate reductase
–
Maleimide + NADPH <=> succinimide + NADP+ 1.14.13.40 anthraniloyl-CoA monooxygenase
–
N-ethylmaleimide + NADPH <=> succinimide + NADP+ 1.14.13.40 anthraniloyl-CoA monooxygenase
–
follicular_fluid_meiosis-activating_sterol + NADPH <=> testicular_meiosis-activating_sterol + NADP+ 1.3.1.70 Delta14-sterol reductase
–
dihydromyricetin + NADPH <=> (2R,3S,4R)-cis-3,4-leucodelphinidin + NADP+ 1.1.1.219 dihydroflavonol 4-reductase
–
1-palmitoyl-2-(5-oxovaleryl)sn-glycero-3-phosphocholine + NADPH <=> 1-palmitoyl-2-(5-hydroxyvaleryl)sn-glycero-3-phosphocholine + NADP+ 1.1.1.21 aldose reductase
–
2,4-cis-tetradecadienoyl-CoA + NADPH <=> 2-cis-dehydroacyl-CoA + NADP+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
2,4-trans-tetradecadienoyl-CoA + NADPH <=> 2-trans-dehydroacyl-CoA + NADP+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
2-(3,4,6-tri-[3,4,5,6-tetrahydro])phthalimido-ethyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-(3,4,6-tri-[3,4,5,6-tetrahydro])phthalimidoethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-(3,5-difluoro)phthalimido-ethyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-(3,5-difluoro)phthalimidoethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-(3-fluoro)phthalimido-ethyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-(3-fluoro)phthalimidoethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-(3-fluoro)phthalimido-methyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-(3-fluoro)phthalimidomethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-(3-methoxy)phthalimido-ethyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-(3-methoxy)phthalimidoethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-(4-fluoro)phthalimido-ethyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-(4-fluoro)phthalimidoethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-(4-methyl)phthalimido-ethyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-(4-methyl)phthalimidoethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-(4-methyl)phthalimido-methyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-(4-methyl)phthalimidomethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-(4-tert-butyl)phthalimido-ethyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-(4-tert-butyl)phthalimidoethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-benzoylpyridine + NADPH <=> (S)-alpha-phenyl-2-pyridylmethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-Methoxybenzaldehyde + NADPH + H+ <=> 2-methoxybenzalcohol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
2-Oxopentanoate + NADPH + NH3 <=> L-norvaline + NADP+ + H2O 1.4.1.4 glutamate dehydrogenase (NADP+)
–
2-phthalimido-ethyl-3-oxobutanoate + NADPH <=> 3-hydroxy-2-phthalimidoethylbutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-benzoylpyridine + NADPH <=> (S)-alpha-phenyl-3-pyridylmethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Isovaleraldehyde + NADPH <=> 3-mehtyl-1-butanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
4-methoxybenzaldehyde + NADPH + H+ <=> 4-methoxybenzalcohol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
4-methylnitrosamino-1-(3-pyridyl)-1-butanone + NADPH <=> 4-methylnitrosamine-1-(3-pyridiyl)-1-butanol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
methylglyoxal + NADPH + H+ <=> (R)-lactataldehyde + NADP+ 1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.78 methylglyoxal reductase (NADH)
–
–
oxidized_8-acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-azabenzo[de]anthracen-10-one + NADPH <=> reduced_8-acetyl-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-azabenzo[de]anthracen-10-one + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
2-methyl-1-pyrroline + NADPH + H+ <=> (R)-2-methylpyrrolidine + (S)-2-methylpyrrolidine + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
(-)-p-Menth-1-ene + NADPH + O2 <=> (-)-trans-Carvotanacetol + NADP+ + H2O 1.14.14.51 (S)-limonene 6-monooxygenase
–
(+)-p-Menth-1-ene + NADPH + O2 <=> (+)-cis-Carvotanacetol + NADP+ + H2O 1.14.14.51 (S)-limonene 6-monooxygenase
–
6,7-dihydroxy-4''-methoxyisoflavone + NADPH + H+ <=> (3S)-2-Dihydrobiochanin_A + NADP+ 1.3.1.46 biochanin-A reductase
–
11alpha-hydroxy-9,15-dioxoprostanoate + NADP+ <=> 15-ketoprostaglandin_E1 + NADPH + H+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
levulinic_acid + NADPH <=> (S)-4-Hydroxypentanoate + NADP+ 1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
–
5-Oxohexanoate + NADPH <=> (S)-5-Hydroxyhexanoate + NADP+ 1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
–
reduced_flavodoxin_I + NADP+ <=> oxidized_flavodoxin_I + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
–
–
1,2-dimethyl-4-(p-carboxyphenylazo)-5-hydroxy-benzene + NADPH <=> 1,2-Dimethyl-4-amino-5-hydroxybenzene + 4-Aminobenzaldehyde + NADP+ 1.7.1.6 azobenzene reductase
–
reduced_flavodoxin_II + NADP+ <=> oxidized_flavodoxin_II + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
–
–
Adamantane + NADPH + O2 <=> 1-Adamantanol + 2-adamantanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
glycine + pyruvate + NADPH <=> D-strombine + NADP+ + H2O 1.5.1.22 strombine dehydrogenase
–
all-trans-retinol + NADPH <=> all-trans-retinal + NADP+ 1.1.1.315 11-cis-retinol dehydrogenase
1.2.1.36 retinal dehydrogenase
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
–
1,2-Cyclohexanedione + NADPH + O2 <=> 1-Oxa-2,3-dioxo-cycloheptane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
Cyclohexan-1,4-dione + NADPH + O2 <=> 1-Oxa-2,5-dioxo-cycloheptane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
delta-thiovalerolactone + NADPH + O2 <=> 1-Oxa-2-oxo-3-thiacycloheptane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
4-Hydroxycyclohexanone + NADPH + O2 <=> 1-Oxa-2-oxo-5-hydroxycycloheptane + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
4-methylcyclohexanone + NADPH + O2 <=> 1-Oxa-2-oxo-5-methylcycloheptane + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
–
4-tert-butylcyclohexanone + NADPH + O2 <=> 1-Oxa-2-oxo-5-tert-butylcycloheptane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
12alpha-Fluoro-11-dehydrocorticosterone + NADPH <=> 12alpha-Fluoro-corticosterone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
3,7,12-Triketo-5beta-cholanoic_acid + NADPH <=> 12beta-Hydroxy-3,7-dioxo-5beta-cholanoate + NADP+ 1.1.1.238 12beta-hydroxysteroid dehydrogenase
–
3,7,12-triketo-5beta-cholanoyl_taurine + NADPH <=> 12beta-Hydroxy-3,7-dioxotaureate + NADP+ 1.1.1.238 12beta-hydroxysteroid dehydrogenase
–
3,12-Dioxo-5beta-cholanoate + NADPH <=> 12beta-Hydroxy-3-oxo-5beta-cholanoate + NADP+ 1.1.1.238 12beta-hydroxysteroid dehydrogenase
–
7,12-Dioxo-5beta-cholanoate + NADPH <=> 12beta-Hydroxy-7-oxo-5beta-cholanoate + NADP+ 1.1.1.238 12beta-hydroxysteroid dehydrogenase
–
13,14-dihydro-15-keto-prostaglandin_F2alpha + NADPH <=> 13,14-Dihydroprostaglandin_F2alpha + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
16beta-Methylcortisol + NADP+ <=> 16beta-Methylcortisone + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
11-deoxycortisol + NADPH <=> 17,21-Dihydroxy-5alpha-pregnan-3,20-dione + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
cortisone + NADPH <=> 17alpha,20beta,21-Trihydroxy-pregn-4-ene-3,11-dione + NADP+ 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
17alpha,20beta-Dihydroxypregn-4-ene-3-one + NADP+ <=> 17alpha-hydroxyprogesterone + NADPH 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
Estrone_3-sulfate + NADPH <=> 17alpha-Estradiol_3-sulfate + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
trans-2-pentenal + NADPH <=> pentanal + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
–
–
–
2,4-Dimethylcinnamyl_alcohol + NADP+ <=> 2,4-dimethylcinnamaldehyde + NADPH 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
cholic_acid + NADP+ <=> 12-ketochenodeoxycholic_acid + NADH + H+ 1.1.1.176 12alpha-hydroxysteroid dehydrogenase
–
cholic_acid + NADP+ <=> 3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic_acid + NADH 1.1.1.159 7alpha-hydroxysteroid dehydrogenase
–
cholic_acid + NADP+ <=> (5beta,7alpha,8xi,12alpha)-7,12-dihydroxy-3-oxocholan-24-oic_acid + NADPH + H+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
Dehydrocholic_acid + NADPH <=> cholic_acid + NADP+ 1.1.1.112 indanol dehydrogenase
–
Tertiary_amine + NADPH + O2 <=> hydoxylamine + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
5,7,3''-trihydroxyisoflavone + NADPH + H+ <=> 2-Dihydrogenistein + NADP+ 1.3.1.46 biochanin-A reductase
–
5,7,3''-trihydroxy-4''-methoxyisoflavone + NADPH + H+ <=> 2-Dihydropratensein + NADP+ 1.3.1.46 biochanin-A reductase
–
3-methylcrotonoyl-CoA + NADPH <=> isovaleryl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
4-Hydroxyhydratropate + NADPH + O2 <=> 2-Methylhomogentisate + NADP+ + H2O 1.14.13.18 4-hydroxyphenylacetate 1-monooxygenase
–
11-deoxycorticosterone + NADPH <=> 20,21-Dihydroxypregn-4-ene-3-one + NADP+ 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
2,3-Dimethylpentane + NADPH + O2 <=> 3,4-Dimethylpentan-2-ol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
3,4-Methylenedioxycinnamyl_alcohol + NADP+ <=> 3,4-Methylenedioxycinnamaldehyde + NADPH 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
2-trans,4-trans-decadienoyl-CoA + NADPH <=> 3-decenoyl-CoA + NADP+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
–
3-Fluoroisocitrate + NADP+ <=> 3-Fluoro-2-oxoglutarate + NADPH + CO2 1.1.1.42 isocitrate dehydrogenase (NADP+)
–
3-hydroxy-4-oxobutanoate + NADP+ + H2O <=> malate + NADPH + H+ 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
–
acetoacetyl-N-acetylcysteamine + NADPH <=> 3-hydroxybutanoyl-N-acetylcysteamine + NADP+ 1.1.1.36 acetoacetyl-CoA reductase
–
acetoacetyl-S-(D-pantetheine)_11-pivalate + NADPH <=> 3-Hydroxybutyryl-S-(D-pantetheine)11-pivalate + NADP+ 1.1.1.36 acetoacetyl-CoA reductase
–
3-Hydroxyisocitrate + NADP+ <=> 3-Hydroxy-2-oxoglutarate + NADPH + CO2 1.1.1.42 isocitrate dehydrogenase (NADP+)
–
4-(1-Naphthylvinyl)pyridine + NADPH <=> 3alpha,12beta-Dihydroxy-5beta-cholanoate + NADP+ 1.1.1.238 12beta-hydroxysteroid dehydrogenase
–
3alpha-Hydroxy-7,12-diketo-5beta-cholanoic_acid + NADPH <=> 3alpha,12beta-Dihydroxy-7-oxo-5beta-cholanoate + NADP+ 1.1.1.238 12beta-hydroxysteroid dehydrogenase
–
3alpha,21-Dihydroxy-5beta-pregnan-20-one + NADP+ <=> 5beta-pregnane-21-ol-3,20-dione + NADPH 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
3alpha-Hydroxy-7,12-diketo-5beta-cholanoic_acid + NADPH <=> 3alpha,7beta-Dihydroxy-12-keto-5beta-cholanoic_acid + NADP+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
Dehydrocholic_acid + NADPH + H+ <=> 3alpha,7beta-Dihydroxy-12-keto-5beta-cholanoic_acid + NADP+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
3alpha-Hydroxy-12-oxo-9,11-cholenic_acid + NADP+ <=> 3,12-Dioxo-9,11-cholenic_acid + NADPH 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
3alpha-Hydroxy-18alpha-glycyrrhetic_acid + NADP+ <=> 3-Keto-18alpha-glycyrrhetic_acid + NADPH 1.1.1.230 3alpha-hydroxyglycyrrhetinate dehydrogenase
–
3beta,17alpha,20alpha-Trihydroxypregn-5-ene + NADP+ <=> 17alpha-hydroxypregnenolone + NADPH 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
17alpha-hydroxypregnenolone + NADPH <=> 3beta,17alpha,20beta-Trihydroxypregn-5-ene + NADP+ 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
3beta,20alpha-Dihydroxypregn-5-ene + NADP+ <=> pregnenolone + NADPH 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
4-Bromocinnamyl_alcohol + NADP+ <=> 4-Bromocinnamaldehyde + NADPH 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
4-Chlorocinnamyl_alcohol + NADP+ <=> 4-Chlorocinnamaldehyde + NADPH 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
4-Methylcinnamyl_alcohol + NADP+ <=> 4-Methylcinnamaldehyde + NADPH 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
5,7,3'',4'',5''-pentahydroxyflavanone + NADPH <=> 5,7,3'',4'',5''-pentahydroxyflavan-4-ol + NADP+ 1.1.1.234 flavanone 4-reductase
–
5-hydroxyundec-cis-2-enoyl-CoA + NADPH <=> 5-hydroxyundecanoyl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
2-decanone + NADPH <=> 2-decanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
5alpha-Androstan-3beta,17alpha-diol + NADP+ <=> epiandrosterone + NADPH 1.1.1.148 estradiol 17alpha-dehydrogenase
–
(-)-alpha-pinene + NADPH + H+ + O2 <=> 6,6-Dimethylbicyclo[3.1.1]hept-2-ene-2-methanol + NADP+ + H2O 1.14.14.31 ipsdienol synthase
–
Quinonoid_6,6-dimethyldihydropterin + NADPH <=> 6,6-Dimethyltetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
Isosepiapterin + NADPH <=> 6-(1-Hydroxypropyl)-dihydropterin + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
3-nonen-2-one + NADPH <=> 2-nonanone + NADP+ 1.3.1.102 2-alkenal reductase (NADP+)
1.3.1.31 2-enoate reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
–
–
–
–
–
naloxone + NADH <=> 6alpha-Naloxol + NADP+ 1.1.1.218 morphine 6-dehydrogenase
–
naloxone + NADPH <=> 6alpha-Naloxol + NADP+ 1.1.1.218 morphine 6-dehydrogenase
–
7alpha-Hydroxy-3,12-dioxo-5beta-cholanoate + NADPH <=> 7alpha,12beta-Dihydroxy-3-oxo-5beta-cholanoate + NADP+ 1.1.1.238 12beta-hydroxysteroid dehydrogenase
–
7,12-Dioxo-5beta-cholanoate + NADPH <=> 7beta-Hydroxy-12-keto-5beta-cholanoic_acid + NADP+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
octan-3-one + NADPH <=> 3-octanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
3,7,12-Triketo-5beta-cholanoic_acid + NADPH <=> 7beta-Hydroxy-3,12-diketo-5beta-cholanoic_acid + NADP+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
3,7,12-triketo-5beta-cholanoyl_taurine + NADPH <=> 7beta-hydroxy-3,12-diketo-5beta-cholanoyl_taurine + NADP+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
3,7-Diketo-5beta-cholanoic_acid + NADPH <=> 7beta-Hydroxy-3-keto-5beta-cholanoic_acid + NADP+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
12-oxo-phytodienoic_acid + NADPH <=> 8-[(1R,2R)-3-Oxo-2-((Z)-pent-2-enyl)cyclopentyl]octanoate + NADP+ 1.3.1.42 12-oxophytodienoate reductase
–
8-Methylpterin + NADPH <=> 8-Methyl-7,8-dihydropterin + NADP+ 1.5.1.3 dihydrofolate reductase
–
9,11-dihydroxy-15-oxoprosta-5,13-dien-1-oic_acid + NADPH <=> 9,11-Dihydroxy-15-oxoprosta-5-en-1-oic_aicd + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
9alpha-Fluoro-11-oxoprogesterone + NADPH <=> 9alpha-Fluoro-11beta-hydroxyprogesterone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
ergosta-5-enol + NADPH + H+ + O2 <=> brassicasterol + crinosterol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
ergosta-5-ene-3beta-ol + NADPH + H+ + O2 <=> brassicasterol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
cycloheptane + NADPH + H+ + O2 <=> cycloheptanol + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
Cycloheptanone + NADPH + H+ <=> cycloheptanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Amaranth + 2 NADPH + 2 H+ <=> alpha-Naphthylamine-4-sulfonic_acid + 4-amino-3-hydroxynaphthalene-2,7-disulfonic_acid + 2 NADP+ 1.7.1.17 FMN-dependent NADH-azoreductase
–
fast_red_E + 2 NADPH + 2 H+ <=> alpha-Naphthylamine-4-sulfonic_acid + 5-amino-6-hydroxynaphthalene-2-sulfonic_acid + 2 NADP+ 1.7.1.17 FMN-dependent NADH-azoreductase
–
1-(4-sulfo-1-naphthylazo)-2-naphthol-3,6-disulfonic_acid + NADPH <=> alpha-Naphthylamine-4-sulfonic_acid + beta-naphthol-3,6-disulfonic_acid + NADP+ 1.7.1.6 azobenzene reductase
–
2,3-dimethoxy-5-methyl-1,4-benzoquinone + NADH <=> reduced_coenzyme_Q0 + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
NADPH + H+ + chloro-1,4-benzoquinone <=> NADP+ + chlorohydroquinone 1.6.5.6 p-benzoquinone reductase (NADPH)
–
Naphthalene + NADPH + O2 <=> 1-naphthol + 2-naphthol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
Naphthalene + NADPH + H+ + O2 <=> 1-naphthol + (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
3-oxododecanoyl-CoA + NADPH <=> (R)-3-hydroxydodecanoyl-CoA + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
beta-D-galactofuranose + NADP+ <=> D-galactono-1,4-lactone + NADPH 1.1.1.120 galactose 1-dehydrogenase (NADP+)
–
4-tert-butylacetophenone + NADPH <=> (1S)-1-(4-tert-butylphenyl)ethanol_(1R)-1-(4-tert-butylphenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Entamoeba_histolytica_thioredoxin_disulfide_41 + NADPH + H+ <=> Entamoeba_histolytica_thioredoxin_41 + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
isatin + NADPH + H+ <=> isatin + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
L-Colitose + NADP+ <=> 3,6-dideoxy-L-galactono-1,5-lactone + NADPH 1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
–
4-methyl-2-oxopentanoate + NADPH + NH3 <=> L-norleucine + NADP+ + H2O 1.4.1.2 glutamate dehydrogenase
–
3-acetylpyridine + NADPH <=> Methyl_3-pyridylcarbinol + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
1-(3-pyridyl)acetone + NADPH + H+ <=> Methyl_3-pyridylcarbinol + NADP+ 1.1.1.B4
–
Dimethylamine + NADPH + H+ + O2 <=> N,N-Dimethylhydroxylamine + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
–
N-Acetyl-leukotriene_E4 + NADPH + O2 <=> N-Acetyl-omega-hydroxy-leukotriene_E4 + NADP+ + H2O 1.14.13.34 leukotriene-E4 20-monooxygenase
–
ethyl_ether + NADPH + O2 <=> ethanol + acetaldehyde + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
N-methylbenzylamine + NADPH + O2 <=> N-Methyl-N-benzyl-hydroxylamine + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
L-citrulline + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-L-citrulline + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
L-cysteine + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-L-Cys + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
L-glutamine + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-L-Gln + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
L-histidine + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-L-His + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
L-methionine + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-L-Met + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
L-serine + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-L-Ser + NADP+ + H2O 1.5.1.11 D-octopine dehydrogenase
–
4-Hydroxy-2-nonanone + NADPH + H+ + O2 <=> 4-hydroxyheptylacetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
oxidized_dichlorophenolindophenol + NADPH + H+ <=> reduced_dicholorophenolindophenol + NADP+ 1.6.5.10 NADPH dehydrogenase (quinone)
–
R1-CO-CHOH-R2 + NADPH <=> R1-CHOH-CHOH-R2 + NADP+ 1.1.1.185 L-glycol dehydrogenase
–
2,3-dimethyl-1,4-naphthoquinone + NADPH <=> Reduced_2,3-dimethyl-1,4-naphthoquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
NADPH + H+ + 2 oxidized_cytochrome_P450_2B4 <=> NADP+ + 2 reduced_cytochrome_P450_2B4 1.6.2.4 NADPH---hemoprotein reductase
–
1''-oxo-2''-D-hydroxypropyl-tetrahydropterin + NADPH <=> (6R,S)-tetrahydrodictyopterin + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
mevaldyl-CoA + H2O <=> mevaldehyde + NADP+ 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
–
Quinonoid_dihydro-2-methylamino-4-hydroxy-6,7-dimethylpteridine + NADPH <=> Tetrahydro-2-methylamino-4-hydroxy-6,7-dimethylpteridine + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
Quinonoid_dihydromonapterin + NADPH <=> tetrahydromonapterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
Quinonoid_dihydroneopterin + NADPH <=> tetrahydromonapterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
trans-1,2-Dihydronaphthalene-1,2-diol + NADP+ <=> 1,2-naphthoquinone + NADPH 1.10.1.1 trans-acenaphthene-1,2-diol dehydrogenase
–
cis-1,4-Dimethylcyclohexane + NADPH + O2 <=> 1-cis-4-Dimethylcyclohexanol + NADP+ + H2O + trans-2,5-dimethylcyclohexanol 1.14.13.25 methane monooxygenase (soluble)
–
cholestane-3beta,5alpha,6beta-triol + NADP+ <=> 6-oxocholestan-3beta,5alpha-diol + NADPH + H+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
ethane + NADPH + O2 <=> ethanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
ethanol + 2 NADP+ + H2O <=> acetate + 2 NADPH + 2 H+ 1.1.1.1 alcohol dehydrogenase
–
3-Ketosteroids + NADPH <=> 3-Hydroxysteroids + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
uracil_in_pre-tRNALeu + NADPH + H+ <=> 5,6-dihydrouracil_in_pre-tRNALeu + NADP+ 1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+]
–
uracil_in_pre-tRNATyr + NADPH + H+ <=> 5,6-dihydrouracil_in_pre-tRNATyr + NADP+ 1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+]
–
uracil_in_tRNA + NADPH + H+ <=> 5,6-dihydrouracil_in_tRNA + NADP+ 1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+]
–
uracil17_in_pre-tRNAPhe + NADPH + H+ <=> 5,6-dihydrouracil17_in_pre-tRNAPhe + NADP+ 1.3.1.88 tRNA-dihydrouridine16/17 synthase [NAD(P)+]
–
cis-2-octenal + NADPH <=> octanal + NADP+ 1.3.1.27 2-hexadecenal reductase
–
octanoyl-CoA + NADPH + H+ <=> octanal + NADP+ 1.2.1.50 long-chain acyl-protein thioester reductase
–
trans-2-octenal + NADPH <=> octanal + NADP+ 1.3.1.27 2-hexadecenal reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
–
4-Piperidone + NADPH <=> Monocyclic_4-hydroxypiperidine + NADP+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
–
–
4-hydroxyphenylacetate + NADPH + O2 <=> 3,4-Dihydroxyphenylacetate + NADP+ + H2O 1.14.14.9 4-hydroxyphenylacetate 3-monooxygenase
–
glutathionylspermidine_disulfide + NADPH <=> 2-Glutathionylspermidine + NADP+ 1.8.1.12 trypanothione-disulfide reductase
–
Xanthopterin-B2 + NADPH <=> 6-(1'',2''-dihydroxypropyl)-dihydrolumazine + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
anthracene + NADPH + H+ + O2 <=> cis-Anthracene_dihydrodiol + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
hexapolyphosphate + NAD+ <=> pentapolyphosphate + NADP+ 2.7.1.23 NAD+ kinase
–
(phosphate)20 + NAD+ <=> polyphosphate(19) + NADP+ 2.7.1.23 NAD+ kinase
–
polyphosphate(25) + NAD+ <=> polyphosphate(24) + NADP+ 2.7.1.23 NAD+ kinase
–
polyphosphate(45) + NAD+ <=> polyphosphate(44) + NADP+ 2.7.1.23 NAD+ kinase
–
polyphosphate(65) + NAD+ <=> polyphosphate(64) + NADP+ 2.7.1.23 NAD+ kinase
–
polyphosphate(75) + NAD+ <=> polyphosphate(74) + NADP+ 2.7.1.23 NAD+ kinase
–
[C173S/C178S_mutant_of_protein-disulfide-oxidoreductase]-disulfide + NADPH + H+ <=> [C173S/C178S_mutant_of_protein-disulfide-oxidoreductase]-dithiol + NADP+ 1.8.1.B4
–
[C173S/C178S_mutant_of_protein-disulfide-oxidoreductase]-disulfide + NADPH + H+ <=> [C173S/C178S_mutant_ofprotein-disulfide-oxidoreductase]-dithiol + NADP+ 1.8.1.B4
–
[C41S/C44S_mutant_of_protein-disulfide-oxidoreductase]-disulfide + NADPH + H+ <=> [C41S/C44S_mutant_of_protein_disulfide_oxidoreductase]-dithiol + NADP+ 1.8.1.B4
–
[C41S/C44S_mutant_of_protein-disulfide-oxidoreductase]-disulfide + NADPH + H+ <=> [C41S/C44S_mutant_ofprotein_disulfide_oxidoreductase]-dithiol + NADP+ 1.8.1.B4
–
20alpha-hydroxyprogesterone + NADPH <=> (5beta,20R)-20-hydroxypregnan-3-one + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
1,5-Anhydro-D-fructose + NADP+ <=> 1,5-anhydro-D-mannitol + NADPH 1.1.1.263 1,5-anhydro-D-fructose reductase
–
Cyclohexanol + NADP+ <=> cyclohexanone + NADH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
Cyclohexanol + NADP+ <=> cyclohexanal + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
–
(+,-)-isopiperitenone + NADP+ <=> 5-methyl-2-(prop-1-en-2-yl)cyclohexan-1-one + NADPH + H+ 1.3.1.82 (-)-isopiperitenone reductase
–
(Z)-3-phenyl-2-nitro-2-butene + NADPH <=> (2R,3R)-3-phenyl-2-nitrobutane + (2S,3R)-3-phenyl-2-nitrobutane + NADP+ 1.3.1.16 beta-nitroacrylate reductase
–
(4-hydroxy-3-[3-methyl-3-butene-1-ynyl]benzaldehyde) + NADPH + H+ <=> (4-hydroxy-3-[3-methyl-3-butene-1-ynyl]benzyl_alcohol) + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
(n-1)-alkanoate + NADPH + H+ + O2 <=> (omega-1)-hydroxy-n-alkanoate + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
ethyl_4-bromo-3-oxobutanoate + NADPH <=> (R)-4-bromo-3-hydroxybutanoic_acid_ethyl_ester + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
5-Fluoroorotate + NADPH <=> (S)-5-fluorodihydroorotate + NADP+ 1.3.1.15 dihydroorotate dehydrogenase (NADP+)
–
1-(p-carboxyphenyl)-5-cyano-3-oxo-1-pentene + NADPH <=> 1-(p-carboxyphenyl)-5-cyano-3-oxo-pentane + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
1-deoxy-6-methyl-D-glucitol + NADP+ <=> 1-deoxy-6-methyl-D-glucose + NADPH 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
–
1-deoxy-6-methyl-D-mannitol + NADP+ <=> 1-deoxy-6-methyl-D-fructose + NADPH 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
–
1-deoxy-D-glucitol + NADP+ <=> 1,5-anhydro-D-glucitol + NADPH 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
–
1-deoxy-D-mannitol + NADP+ <=> 1-deoxy-D-fructose + NADPH 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
–
N-Methyl-4-piperidone + NADPH <=> 1-methylpiperidin-4-ol + NADP+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
–
–
decylamine + NADPH + O2 <=> 1-nitrosodecane + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
n-octylamine + NADPH + O2 <=> 1-nitrosooctane + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
N-propylyl-4-piperidone + NADPH <=> 1-propylpiperidin-4-ol + NADP+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
–
–
11alpha,15(S)-dihydroxy-9-ketoprost-5,13-dienoic_acid + NADP+ <=> 11alpha-hydroxy-9,15-diketoprost-5,13-dienoic_acid + NADH 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+)
–
cortisol + NADPH <=> 11beta,17alpha,21-trihydroxypregnan-3,20-dione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
androst-4-ene-3,11,17-trione + NADPH <=> 11beta-hydroxyandrost-4-ene-3,17-one + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
19-nortestosterone + NADPH <=> 17-hydroxyestran-3-one + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
11-deoxycortisol + NADPH <=> 17alpha,21-dihydroxy-pregnan-3,20-dione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
17alpha-methylestr-4-en-3-one + NADPH <=> 17alpha-methylestran-3-one + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
17beta-methyl-androsta-4,9-dien-3-one + NADPH <=> 17beta-methyl-5alpha-androst-9-en-3-one + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
2'',7-dihydroxy-3'',4''-methylenedioxyisoflavone + NADPH <=> 2'',7-hydroxy-dihydro-3'',4''-methylenedioxyisoflavone + NADP+ 1.3.1.45 2'-hydroxyisoflavone reductase
–
2,3-benzoylphenyl-propanoic_acid + NADPH <=> 2,3-benzoylphenyl-propanol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
2,3-heptanedione + NADPH <=> 2,3-heptanediol + NADP+ 1.1.1.112 indanol dehydrogenase
–
2-chloroheptanal + NADPH <=> 2-chloroheptanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
trans-3-(2-furyl)acrolein + NADPH <=> 2-furylpropanal + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
2 Fe(II)-cytochrome_c + NADP+ + H+ <=> 2 Fe(III)-cytochrome_c + NADPH 1.16.1.9 ferric-chelate reductase (NADPH)
–
Fe(III)-o,o-EDDHA_I + NADPH <=> Fe(II)-o,o-EDDHA_I + NADP+ + H+ 1.16.1.9 ferric-chelate reductase (NADPH)
–
magnesium_protoporphyrin_monomethyl_ester + NADPH + O2 <=> magnesium-divinyl-protochlorophyllide + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
2-Methylacetoacetate + NADPH + H+ <=> 2-methyl-3-hydroxybutyrate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
2-methylundecanal + NADPH <=> 2-methylundecanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
chlorophyllide_d + O2 + NADPH + H+ <=> [7-formyl]-chlorophyllide_d + H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
cucurbitacin_A + NADPH <=> 23,24-dihydrocucurbitacin_A + NADP+ 1.3.1.5 cucurbitacin Delta23-reductase
–
cucurbitacin_C + NADPH <=> 23,24-dihydrocucurbitacin_C + NADP+ 1.3.1.5 cucurbitacin Delta23-reductase
–
cucurbitacin_D + NADPH <=> 23,24-dihydrocucurbitacin_D + NADP+ 1.3.1.5 cucurbitacin Delta23-reductase
–
cucurbitacin_E + NADPH <=> 23,24-dihydrocucurbitacin_E + NADP+ 1.3.1.5 cucurbitacin Delta23-reductase
–
cucurbitacin_E_beta-D-glucoside + NADPH <=> 23,24-dihydrocucurbitacin_E_beta-D-glucoside + NADP+ 1.3.1.5 cucurbitacin Delta23-reductase
–
cucurbitacin_F + NADPH <=> 23,24-dihydrocucurbitacin_F + NADP+ 1.3.1.5 cucurbitacin Delta23-reductase
–
24-methylenepollinastanone + NADPH + acetate <=> 24-methylenepollinastanol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
24RS-dihydrocycloeucalenone + NADPH <=> 24RS-dihydrocycloeucalenol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
etoposide + NADPH + O2 <=> 3''-demethyletoposide + NADP+ + H2O 1.14.14.55 quinine 3-monooxygenase
–
3,4,5-trimethoxybenzaldehyde + NADPH <=> 3,4,5-trimethoxybenzyl_alcohol + NADP+ 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
3,5,5-trimethylcyclohex-2-en-1-one + NADP+ <=> 3,3,5-trimethylcyclohexanone + NADPH + H+ 1.3.1.82 (-)-isopiperitenone reductase
–
NADPH + 3-acetylpyridine-NAD(P)+ <=> NADP+ + 3-acetylpyridine_adenine_dinucleotide_phosphate(H) 1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)
–
5beta-Dihydrocortisol + NADPH <=> 3alpha,5beta-tetrahydrocortisol + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
3-oxocholate + NADPH <=> 3alpha-hydroxycholic_acid + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
DELTA7-cholestenone + NADPH <=> 3beta-hydroxy-cholest-7-ene + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
4,4-dimethyl-5alpha-cholesta-7,14-dien-3beta-ol + NADPH <=> 4,4-dimethyl-5alpha-cholesta-7-en-3beta-ol + NADP+ 1.3.1.70 Delta14-sterol reductase
–
4-benzyloxy-3-methoxybenzaldehyde + NADPH + H+ <=> 4-benzyloxy-3-methoxybenzyl_alcohol + NADP+ 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
trans-4-furyl-3-buten-2-one + NADPH <=> 4-furyl-butane-2-one + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
4alpha-methyl-8,14,24(28)-ergostatrien-3beta-ol + NADPH <=> 4alpha-methyl-8,24(28)-ergostadien-3beta-ol + NADP+ 1.3.1.70 Delta14-sterol reductase
–
4beta-methyl-28-nor-24RS-dihydrocycloeucalenone + NADPH <=> 4beta-methyl-28-nor-24RS-dihydrocycloeucalenol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
3,4''-dichlorobiphenyl + NADPH + O2 <=> 5,6-dihydroxy-3,4''-dichlorobiphenyl + NADP+ 1.14.12.18 biphenyl 2,3-dioxygenase
–
N-methylimidazoleacetate + NADPH + O2 + H+ <=> 5-hydroxy-N-methylimidazoleacetate + NADP+ + H2O 1.14.13.5 imidazoleacetate 4-monooxygenase
–
Imidazolepropionate + NADPH + O2 + H+ <=> 5-hydroxyimidazolepropionate + NADP+ + H2O 1.14.13.5 imidazoleacetate 4-monooxygenase
–
3-(1H-imidazol-4-yl)-2-oxopropanoate + O2 + NADPH + H+ <=> 5-hydroxyimidazolepyruvate + NADP+ + H2O 1.14.13.5 imidazoleacetate 4-monooxygenase
–
cholestanol + NADPH + O2 <=> 5alpha-cholestan-3beta,7alpha-diol + NADP+ + H2O 1.14.14.23 cholesterol 7alpha-monooxygenase
–
5beta-androstane-3,17-dione + NADPH <=> 5beta-androstan-17one-3-ol + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
4beta-(S-cysteinyl)-epicatechin + NADPH + H+ <=> epicatechin + L-cysteine + NADP+ 1.17.1.3 leucoanthocyanidin reductase
–
2-trans-8,11-eicosatrienoyl-CoA + NADPH <=> 8,11-eicosadienoyl-CoA + NADP+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
cholesta-8,14-dien-3beta-ol + NADPH <=> 8-lanostene-3beta-ol + NADP+ 1.3.1.70 Delta14-sterol reductase
–
8-thiabicyclo(3,2,1)octane-3-one + NADPH <=> 8-thiabicyclo(3,2,1)octane-3-ol + NADP+ 1.1.1.206 tropinone reductase I
–
alpha,beta-L-arabinose + NADP+ <=> L-arabinono-1,4-lactone + NADPH 1.1.1.120 galactose 1-dehydrogenase (NADP+)
–
benzosuberol + NADP+ <=> benzosuberone + NADPH 1.1.1.112 indanol dehydrogenase
–
chalcone + NADPH <=> benzylacetophenone + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
(2E)-2-benzylidenecyclohexanone + NADPH <=> benzylcyclohexan-2-one + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
Camphorquinone + NADPH + H+ <=> camphorquinol + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
–
–
–
cholestan-3beta-ol + NADPH + H+ <=> cholesta-7-en-3beta-ol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
cis-4-heptenal + NADP+ <=> cis-4-heptenol + NADPH 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
citral + NADPH <=> citrol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
crotonaldehyde + NADPH + H+ <=> crotonyl_alcohol + NADP+ 1.1.1.90 aryl-alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
Acetoacetyl-N-cysteamine + NADPH <=> D-3-hydroxybutyryl-N-cysteamine + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
D-fructose + NADPH + H+ <=> D-arabino-hexitol + NADP+ 1.1.1.21 aldose reductase
–
DELTA7-chondrillastenone + NADPH <=> DELTA7-chondrillasterol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
Dimethyl_2-methyl-3-oxosuccinate + NADPH <=> dimethyl_2-methyl-3-hydroxysuccinate + NADP+ 1.1.1.229 diethyl 2-methyl-3-oxosuccinate reductase
–
NADPH + ferricytochrome_P450 <=> ferrocytochrome_P450 + NADP+ 1.6.2.4 NADPH---hemoprotein reductase
–
ergosta-5,7,22-trien-3beta-ol + NADPH <=> ergosta-5,22-diene-3beta-ol + NADP+ 1.3.1.21 7-dehydrocholesterol reductase
–
ergosta-5,7-diene-3beta-ol + NADPH <=> ergosta-5-ene-3beta-ol + NADP+ 1.3.1.21 7-dehydrocholesterol reductase
–
ergosta-8,14-dien-3beta-ol + NADPH <=> ergosta-8-en-3beta-ol + NADP+ 1.3.1.70 Delta14-sterol reductase
–
16-ketoestradiol + NADPH <=> estra-1,3,5(10)triene-3,16alpha,17-triol + NADP+ 1.1.1.147 16alpha-hydroxysteroid dehydrogenase
–
estradiol-17alpha_3-galacturonide + NADP+ <=> estrone_3-galacturonide + NADPH 1.1.1.148 estradiol 17alpha-dehydrogenase
–
estradiol-17alpha_3-glucoside + NADP+ <=> estrone-3-beta-D-glucoside + NADPH 1.1.1.148 estradiol 17alpha-dehydrogenase
–
ethyl_2-oxocyclohexanecarboxylate + NADPH <=> ethyl_(1R,2S)-2-hydroxycyclohexanecarboxylate + NADP+ 1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
–
ethyl_2-oxocyclopentanecarboxylate + NADPH <=> ethyl_(1R,2S)-2-hydroxycyclopentanecarboxylate + NADP+ 1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
–
ethyl_5-oxohexanoate + NADPH <=> ethyl-5-hydroxyhexanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
(+)-isomenthone + NADPH + H+ <=> (-)-menthol + NADP+ 1.1.1.207 (-)-menthol dehydrogenase
–
(-)-limonene + NADPH + O2 <=> (-)-trans-carveol + NADP+ + H2O 1.14.14.51 (S)-limonene 6-monooxygenase
–
(-)-limonene + NADPH + O2 <=> (-)-trans-isopiperitenol + NADP+ + H2O 1.14.13.47 (S)-limonene 3-monooxygenase
1.14.14.51 (S)-limonene 6-monooxygenase
–
–
(-)-trans-isopiperitenol + NADP+ <=> (-)-isopiperitenone + NADPH + H+ 1.1.1.223 isopiperitenol dehydrogenase
1.1.1.243 carveol dehydrogenase
–
–
(+)-isomenthone + NADPH + H+ <=> (+)-neomenthol + NADP+ 1.1.1.208 (+)-neomenthol dehydrogenase
–
acetohexamide + NADPH <=> hydroxyhexamide + NADP+ 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
pentose + NADPH <=> i-ribitol + NADP+ 1.1.1.21 aldose reductase
–
iodoacetaldehyde + NADPH <=> iodoethan-2-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
iodohexadecanal + NADPH <=> iodohexadecanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
linolenyl_aldehyde + NADPH <=> linolenol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
linoleyl_aldehyde + NADPH <=> linoleol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
menogarol + NADP+ <=> 7-deoxynogarol + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
keto-omega-methylpantoyl_lactone + NADPH <=> methylpantoyl_lactone + NADP+ 1.1.1.214 2-dehydropantolactone reductase (Si-specific)
–
dTDP-glucose + 2 NADP+ + H2O <=> TDP-D-galacturonate + 2 NADPH + 2 H+ 1.1.1.186 dTDP-galactose 6-dehydrogenase
–
2-Methoxybenzaldehyde + NADPH + H+ <=> 2-Methoxybenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
N-iso-propylnortropinone + NADPH <=> N-isopropylnortropan-3-ol + NADP+ 1.1.1.206 tropinone reductase I
–
Methimazole + NADPH + O2 <=> N-methylmethimidazole-2-sulfinic_acid + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2-Bromobenzaldehyde + NADPH + H+ <=> o-bromobenzyl_alcohol + NADP+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
octyl_4-chloro-3-oxobutanoate + NADPH <=> octyl-4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
11-deoxycorticosterone + NADPH <=> pregnan-21-ol-3,20-dione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
progesterone + NADPH <=> pregnan-3,20-dione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
quinuclidin-3-ol + NADP+ <=> 3-quinuclidinone + NADPH + H+ 1.1.1.206 tropinone reductase I
1.1.1.B51
–
–
spinastenone + NADPH <=> spinasterol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
4-tetrahydro-thiopyranone + NADPH <=> tetrahydrothiopyran-4-ol + NADP+ 1.1.1.236 tropinone reductase II
–
trans-2-decenal + NADPH <=> trans-2-decen-1-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
trans-2-octenal + NADPH + H+ <=> trans-2-octen-1-ol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
trans-4-phenyl-3-buten-2-one + NADPH <=> trans-4-phenyl-3-buten-2-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene + NADP+ <=> 7,8-benzo[a]pyrenequinone + NADPH 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
beta-lapachone + NADPH <=> 3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-diol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
5alpha-pregnane-21-ol-3,20-dione + NADPH <=> 5beta-Pregnan-3alpha,21-diol-20-one + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
6,7-dihydro-5H-benzocycloheptene + NADPH + O2 <=> (-)-cis-(1R,2S)-dihydroxybenzocycloheptane + NADP+ 1.14.12.18 biphenyl 2,3-dioxygenase
–
1,4-dithiane + NADPH + H+ + O2 <=> (R)-dithiane_sulfoxide + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
ethyl_phenyl_sulfide + NADPH + H+ + O2 <=> (R)-ethyl_phenyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
methyl_(2-pyridyl)_sulfide + NADPH + H+ + O2 <=> (R)-methyl_(2-pyridyl)_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
phenyl_propyl_sulfide + NADPH + H+ + O2 <=> (R)-propyl_phenyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
ethyl_p-tolyl_sulfide + NADPH + O2 <=> (S)-ethyl_p-tolyl_sulfoxide + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
1,1-bisnorsqualene + NADPH + O2 <=> bisnorsqualene_oxide + NADP+ + H2O 1.14.14.17 squalene monooxygenase
–
Aclarubicin + NADP+ <=> 7-deoxyaklavinone + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
1,4-dimethoxymethylbenzoquinone + NADPH <=> 1,4-dimethoxymethylhydrobenzoquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
1-methylsqualene + NADPH + O2 <=> 1-methyl-squalene-2,3-epoxide + NADP+ + H2O 1.14.14.17 squalene monooxygenase
–
1-norsqualene + NADPH + O2 <=> 1-norsqualene-2,3-epoxide + NADP+ + H2O 1.14.14.17 squalene monooxygenase
–
10,11,14,15-tetrahydrosqualene + NADPH + O2 <=> 10,11,14,15-tetrahydro-squalene-2,3-epoxide + NADP+ + H2O 1.14.14.17 squalene monooxygenase
–
10,11-dihydrosqualene + NADPH + O2 <=> 10,11-dihydro-squalene-2,3-epoxide + NADP+ + H2O 1.14.14.17 squalene monooxygenase
–
10-formyl-5,8-dideazafolate_tetraglutamate + NADP+ + H2O <=> 5,8-dideazafolate_tetraglutamate + CO2 + NADPH + H+ 1.5.1.6 formyltetrahydrofolate dehydrogenase
–
10-formyltetrahydropteroylhexaglutamate + NADP+ + H2O <=> tetrahydropteroylhexaglutamate + CO2 + NADPH 1.5.1.6 formyltetrahydrofolate dehydrogenase
–
19-nortestosterone + NADPH + O2 <=> 11alpha-hydroxy-19-nortestosterone + NADP+ + H2O 1.14.99.14 progesterone 11alpha-monooxygenase
–
(24R),25-dihydroxycholecalciferol + NADPH + O2 <=> 1alpha,24,25-trihydroxycholecalciferol + NADP+ + H2O 1.14.15.18 calcidiol 1-monooxygenase
–
(3S)-2,3-epoxy-2,3-dihydrosqualene + NADPH + O2 <=> 2,3,22,23-dioxidosqualene + NADP+ + H2O 1.14.14.17 squalene monooxygenase
–
2,3,6-trichlorophenol + NADPH + O2 <=> 2,3,5-trichlorohydroquinone + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
prostaglandin_E2 + NADP+ <=> prostaglandin_F2alpha + NADPH 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
–
prostaglandin_H2 + NADPH <=> prostaglandin_E2 + NADP+ 1.1.1.189 prostaglandin-E2 9-reductase
–
2,6-dimethoxy-1,4-benzoquinone + NADPH <=> 2,6-dimethoxy-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
nicotinate + NADPH + O2 + H2O <=> 2-(acetylaminomethylene)succinate + NADP+ + H2O 1.14.13.241 5-pyridoxate monooxygenase
–
2-ethyl-1,4-naphthoquinone + NADPH <=> 2-ethyl-1,4-hydronaphthoquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-hydroxyamino-6-oxopimelate + H2O + NADP+ <=> 2-hydroxyamino-6-oxopimelate + NH3 + NADPH 1.4.1.16 diaminopimelate dehydrogenase
–
2-hydroxymethyl-5-methoxy-2,5-cyclohexadiene-1,4-dione + NADPH <=> 2-hydroxymethyl-5-methoxy-2,5-cyclohexadiene-1,4-diol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-methoxy-1,4-benzoquinone + NADPH <=> 2-methoxy-2,5-cyclohexadiene-1,4-diol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-methoxy-5-(methoxymethyl)-2,5-cyclohexadiene-1,4-dione + NADPH <=> 2-methoxy-5-methoxymethyl-2,5-cyclohexadiene-1,4-diol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
5-methylmaleylacetate + NADH <=> 2-methyl-3-oxoadipate + NADP+ 1.3.1.32 maleylacetate reductase
–
5-methylmaleylacetate + NADPH <=> 2-methyl-3-oxoadipate + NADP+ 1.3.1.32 maleylacetate reductase
–
vitamin_K + NADPH <=> 2-methyl-3-phytyl-1,4-naphthohydroquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-Methylbenzoate + NADPH + O2 <=> 2-methyl-4-hydroxybenzoate + NADP+ + H2O 1.14.14.92 benzoate 4-monooxygenase
–
mesaconate + NADPH <=> 2-methylbutanedioic_aicd + NADP+ 1.3.1.31 2-enoate reductase
–
methyl_2-phenylethyl_sulfide + NADPH + H+ + O2 <=> 2-phenylethyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2-Nitrophenol + NADPH + O2 <=> 3-nitrocatechol + NADP+ + H2O 1.14.13.31 2-nitrophenol 2-monooxygenase
–
cortisol + NADPH <=> 3beta,11beta,17alpha,21-tetrahydroxy-4-pregnen-20-one + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
5alpha-pregnan-11beta,17alpha,21-triol-3,20-dione + NADPH <=> 3beta,11beta,17alpha,21-tetrahydroxy-5alpha-pregnan-20-one + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
11beta,17alpha,21-trihydroxy-5beta-pregnane-3,20-dione + NADPH <=> 3beta,11beta,17alpha,21-tetrahydroxy-5beta-pregnan-20-one + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
17alpha-hydroxyprogesterone + NADPH <=> 3beta,17-dihydroxy-4-pregnen-20-one + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
27-Hydroxycholesterol + NADPH + H+ + O2 <=> 3beta,7alpha-dihydroxy-5-cholestenoic_acid + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
progesterone + NADPH <=> 3beta-hydroxy-4-pregnen-20-one + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
(Z)-ajoene + NADPH + H+ <=> 4,5,9-trithiadodeca-1,6,11-triene + 4,8,9,13-tetrathiahexadeca-1,6,10,15-tetraene + NADP+ 1.8.1.7 glutathione-disulfide reductase
–
ajoene + NADPH <=> 4,5,9-trithiadodeca-1,6,11-triene + NADP+ 1.8.1.7 glutathione-disulfide reductase
–
4,5-dimethoxy-1,2-benzoquinone <=> 4,5-dimethoxy-3,5-cyclohexadiene-1,2-diol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
ajoene + NADPH <=> 4,8,9,13-tetrathiahexadeca-1,6,1,15-tetraene + NADP+ 1.8.1.7 glutathione-disulfide reductase
–
24-methylidenecycloartanol + NADPH + O2 + H+ <=> cycloeucalenol + NADP+ + H2O 1.14.18.10 plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase
–
cycloeucalenone + NADPH + O2 + H+ <=> cycloeucalenol + NADP+ + H2O 1.14.18.10 plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase
–
3-methylthiopropionaldehyde + NADPH + H+ <=> 2-hydroxyethyl_methyl_sulfide + NADP+ 1.1.1.265 3-methylbutanal reductase
–
4-hydroxylysine + NADP+ <=> alpha-amino-gamma-hydroxyadipate-semialdehyde + NADPH 1.4.1.15 lysine dehydrogenase
–
4-methylene_diaminopimelate + H2O + NADP+ <=> 4-methyleneamino-6-oxopimelate + NH3 + NADPH 1.4.1.16 diaminopimelate dehydrogenase
–
5,8-Dihydroxy-1,4-naphthoquinone + NADPH <=> 5,8-dihydroxynaphthohydroquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
–
–
5-(1-aziridinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-propenyl)-1-methyl-1H-indole-4,7-dione + NADPH <=> 5-(1-aziridinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-propenyl)-1-methyl-1H-indole-4,7-diol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
5-hydroxycyclohex-1-enecarbonyl-CoA + NADPH <=> 5-hydroxycyclohexylcarbonyl-CoA + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
deoxycholoyl-CoA + NADP+ <=> 3-oxodeoxycholoyl-CoA + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
2-methylmaleylacetate + NADPH <=> 5-methyl-3-oxoadipate + NADP+ 1.3.1.32 maleylacetate reductase
–
11-deoxycortisol + NADPH + O2 <=> cortisol + NADP+ + H2O 1.14.15.4 steroid 11beta-monooxygenase
–
topaquinone + NADPH <=> topaquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
bromobenzene + NADPH + O2 <=> bromophenol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
chloronaphthalene + NADPH + O2 <=> chloronaphthol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
1-Chloropentane + NADPH + O2 <=> chloropentanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
11-Dehydrocorticosterone + NADPH + H+ <=> cortisone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
17alpha-hydroxy-pregn-4-ene-3,11,20,21-tetraone + NADPH <=> cortisone + NADP+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
12-oxo-phytodienoic_acid + NADPH <=> cis-3-oxo-2-(2''-pentenyl)cyclopentane-1-octanoic_acid + NADP+ 1.3.1.42 12-oxophytodienoate reductase
–
cyclized-dopamine_o-hydroquinone + NADH <=> cyclized-dopamine_o-hydroquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
cyclized-dopamine_o-hydroquinone + NADPH <=> cyclized-dopamine_o-hydroquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
cyclohexyl_methyl_sulfide + NADPH + O2 <=> cyclohexyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
cyclopentyl_methyl_sulfide + NADPH + O2 <=> cyclopentyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
2,3-dichlorophenol + NADPH + O2 <=> dichlorocatechol + NADP+ + H2O 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
–
benzophenone + NADPH + H+ <=> diphenylmethanol + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
eicosenoyl-CoA + NADPH + H+ <=> eicosenyl_alcohol + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
erucoyl-CoA + NADPH + H+ <=> erucyl_alcohol + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
ethyl_acetoacetate + NADPH + H+ <=> ethyl_(S)-3-hydroxybutanoate + NADP+ 1.1.1.B3
–
3-indolylacryloyl-CoA + NADPH + CO2 + H+ <=> indolylmethylmalonyl-CoA + NADP+ 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
methyl_2-phenylacrylate + NADP+ <=> methyl_(2R)-2-methyl-3-phenylpropanoate + NADPH + H+ 1.3.1.31 2-enoate reductase
1.6.99.1 NADPH dehydrogenase
–
–
ethyl-(2R)-ethylacetoacetate + NADPH <=> ethyl_(2R,3S)-2-ethyl-3-hydroxybutanoate + NADP+ 1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
–
ethyl_2-ethylacetoacetate + NADPH <=> ethyl_(2R,3S)-2-ethyl-3-hydroxybutanoate + NADP+ 1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
GDP-4-dehydro-6-deoxy-D-mannose + NADPH <=> GDP-D-talometylose + NADP+ 1.1.1.187 GDP-4-dehydro-D-rhamnose reductase
–
indolequinones + NADPH <=> indolehydroquinones + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
1-nitro-4-(methylsulfanyl)benzene + NADPH + H+ + O2 <=> methyl_p-nitrophenyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
L-ornithine + 2-oxoglutarate + NADPH <=> N2-(1,3-dicarboxypropyl)-L-ornithine + NADP+ + H2O 1.5.1.19 D-nopaline dehydrogenase
–
L-threonate + NADP+ <=> 2-dehydro-L-erythronate + NADPH + H+ 1.1.1.411 L-threonate 2-dehydrogenase
–
L-ornithine + 3-Fluoropyruvate + NADPH <=> N6-(1-carboxy-2-fluoroethyl)ornithine + NADP+ + H2O 1.5.1.24 N5-(carboxyethyl)ornithine synthase
–
L-lysine + pyruvate + NADPH <=> N7-(1-carboxyethyl)lysine + NADP+ + H2O 1.5.1.24 N5-(carboxyethyl)ornithine synthase
–
1-methoxy-4-(methylsulfanyl)benzene + NADPH + H+ + O2 <=> p-methoxyphenyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
oxidized_lipoamide + NADPH <=> Lipoamide + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
Lipoamide + NADPH + H+ <=> Lipoamide + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
reduced_2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone + NADP+ + H+ <=> oxidized_2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
racemic_ipsenol + NADP+ <=> ipsenone + NADPH + H+ 1.1.1.386 ipsdienol dehydrogenase
–
(2R,5S)-2,5-diaminopentanoate + H2O + NADP+ <=> (2R)-2-amino-5-oxopentanoate + NH3 + NADPH + H+ 1.4.1.12 2,4-diaminopentanoate dehydrogenase
–
Hordeum_vulgare_thioredoxin_2 + NADP+ <=> Hordeum_vulgare_thioredoxin_2_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
Hordeum_vulgare_thioredoxin_1 + NADP+ <=> Hordeum_vulgare_thioredoxin_1_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
Arabidopsis_thaliana_thioredoxin_3 + NADP+ <=> Arabidopsis_thaliana_thioredoxin_3_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
Hordeum_vulgare_thioredoxin_2_mutant_I51G + NADP+ <=> Hordeum_vulgare_thioredoxin_2_mutant_I51G_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
Hordeum_vulgare_thioredoxin_2_mutant_G57P + NADP+ <=> Hordeum_vulgare_thioredoxin_2_mutant_G57P_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
Hordeum_vulgare_thioredoxin_2_mutant_E86A + NADP+ <=> Hordeum_vulgare_thioredoxin_2_mutant_E86A_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
Babesia_bovis_thioredoxin + NADP+ <=> Babesia_bovis_thioredoxin_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
a_[(3S)-4-alkanoyl-5-oxooxolan-3-yl]methyl_phosphate + NADP+ <=> a_(4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl_phosphate + NADPH + H+ 1.3.1.113 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase
–
2,3,3-trimethyl-3H-indole + NADPH + H+ <=> (R)-2,3,3-trimethylindoline + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
1,3,6,8-Tetrahydroxynaphthalene + NADPH + H+ <=> (R)-scytalone + NADP+ 1.1.1.B57
–
2 thioanisole + NADPH + H+ + O2 <=> (R)-thioanisole_sulfoxide + (S)-thioanisole_sulfoxide + 2 NADP+ + 2 H2O 1.14.13.22 cyclohexanone monooxygenase
–
1,3,8-Trihydroxynaphthalene + NADPH + H+ <=> (R)-vermelone + NADP+ 1.1.1.B57
–
vitamin_K2 + NADPH <=> reduced_vitamin_K2 + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
5-hydroxy-2,3-dihydronaphthalene-1,4-dione + NADPH + H+ <=> (S)-4,8-dihydroxy-1-tetralone + NADP+ 1.1.1.B57
–
2,3-dihydronaphthalene-1,4-dione + NADPH + H+ <=> (S)-4-hydroxy-1-tetralone + NADP+ 1.1.1.B57
–
alpha-tetralone + NADPH + H <=> (S)-4-hydroxy-1-tetralone + NADP+ 1.1.1.B57
–
5-methoxy-1-tetralone + NADPH + H <=> (S)-4-hydroxy-5-methoxy-1-tetralone + NADP+ 1.1.1.B57
–
6-methoxy-1-tetralone + NADPH + H <=> (S)-4-hydroxy-6-methoxy-1-tetralone + NADP+ 1.1.1.B57
–
indan + NADPH + H+ <=> (S)-4-hydroxy-indan + NADP+ 1.1.1.B57
–
1,2,3,4-tetrahydronaphthalene + NADPH + H+ <=> (S)-4-hydroxy-tetralin + NADP+ 1.1.1.B57
–
dibenzofuran + NADPH + H+ + O2 <=> 1,2-dihydrobenzofuran + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
NADPH + H+ + 1-[3-(4-phenoxyphenoxy)-2-oxopropyl]indole-5-carboxylic_acid <=> NADP+ + 1-[2-hydroxy-3-(4-phenoxyphenoxy)propyl]indole-5-carboxylic_acid 1.6.2.4 NADPH---hemoprotein reductase
–
2-Cys_peroxiredoxin_A + NADPH + H+ <=> 2-Cys_peroxiredoxin_A_disulfide + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
2-Cys_peroxiredoxin_B + NADPH + H+ <=> 2-Cys_peroxiredoxin_B_disulfide + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
2-dehydro-D-gulonate + NADP+ <=> 2,5-didehydro-D-gluconate + NADPH + H+ 1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
–
2-methyl-3,4-dihydroisoquinolin-2-ium + NADPH + H+ <=> 2-methyl-1,2,3,4-tetrahydroisoquinoline + NADP+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
2-hydroxyethyl_disulfide + NADPH + H+ <=> 2 2-sulfanylethan-1-ol + NADP+ 1.8.1.B1
–
solketal + NADP+ <=> (4R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde + NADPH 1.1.1.72 glycerol dehydrogenase (NADP+)
–
1-Indanone + NADPH + H <=> 3-hydroxy-1-indanone + NADP+ 1.1.1.B57
–
2-hydroxy-3-methyl-1,4-naphthoquinone + NADPH + H+ <=> 3-methylnaphthalene-1,2,4-triol + NADP+ 1.6.5.5 NADPH:quinone reductase
–
2,4,6-trinitrotoluene + NADPH + H+ <=> 4-hydroxyamino-2,6-dinitrotoluene + NADP+ + H2O 1.7.1.B2
–
NADPH + H+ + 4-nitroso-2,6-dinitrotoluene <=> NADP+ + 4-hydroxyamino-2,6-dinitrotoluene 1.6.2.4 NADPH---hemoprotein reductase
–
4-methylthioheptyl-glucosinolate + NADPH + H+ + O2 <=> 4-methylsulfinylheptyl-glucosinolate + NADP+ + H2O 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
4-methylthiohexyl-glucosinolate + NADPH + H+ + O2 <=> 4-methylsulfinylhexyl-glucosinolate + NADP+ + H2O 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
4-methylthiooctyl-glucosinolate + NADPH + H+ + O2 <=> 4-methylsulfinyloctyl-glucosinolate + NADP+ + H2O 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
4-methylthiopentyl-glucosinolate + NADPH + H+ + O2 <=> 4-methylsulfinylpentyl-glucosinolate + NADP+ + H2O 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
4-methylthiopropyl-glucosinolate + NADPH + H+ + O2 <=> 4-methylsulfinylpropyl-glucosinolate + NADP+ + H2O 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
12-oxo-trans-phythodienoic_acid + NADPH <=> t-3-oxo-2-(2''-pentenyl)cyclopentaneoctanoic_acid + NADP+ 1.3.1.42 12-oxophytodienoate reductase
–
5-bromo-L-kynurenine + NADPH + H+ + O2 <=> 5-bromo-3-hydroxy-L-kynurenine + NADP+ + H2O 1.14.13.9 kynurenine 3-monooxygenase
–
5-cyanopyrrolo[2,3-d]pyrimidin-4-one + 2 NADPH + 2 H+ <=> 7-aminomethyl-7-carba-2-deaminoguanine + 2 NADP+ 1.7.1.13 preQ1 synthase
–
NADPH + H+ + doxorubicin <=> NADP+ + 7-deoxydoxorubicinone 1.6.2.4 NADPH---hemoprotein reductase
–
anthraquinone-2-sulfonate + NADPH + H+ <=> 9,10-anthraquinol-2-sulfonic_acid + NADP+ 1.6.5.5 NADPH:quinone reductase
–
almotriptan + NADPH + H+ + O2 <=> almotriptan_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
1,4-dihydroxy-9,10-anthraquinone + NADPH + H+ <=> anthracene-1,4,9,10-tetrol + NADP+ 1.6.5.5 NADPH:quinone reductase
–
1,8-dihydroxy-9,10-anthraquinone + NADPH + H+ <=> anthracene-1,8,9,10-tetrol + NADP+ 1.6.5.5 NADPH:quinone reductase
–
7,8-dihydropteroate + NADPH <=> tetrahydropteroate + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
(2E,6E)-farnesyl_diphosphate + geranylgeranyl_diphosphate + NADPH + H+ <=> C35H58 + NADP+ 2.5.1.148 lycopaoctaene synthase
–
CHLI-1_ATPase + NADPH + H+ <=> CHLI-1_ATPase_disulfide + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
flaviolin + NADPH + H+ <=> cis-(3S,4R)-4-hydroxyscytalone + NADP+ 1.1.1.B57
–
2-Hydroxy-1,4-naphthoquinone + NADPH + H+ <=> cis-3,4-dihydroxy-1-tetralone + NADP+ 1.1.1.B57
–
Deprenyl + NADPH + H+ + O2 <=> deprenyl_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
desulfo-4-methylsulfinylbutyl-glucosinolate + NADPH + H+ + O2 <=> desulfo-4-methylsulfinylbutyl-glucosinolate + NADP+ + H2O 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
trans-3,4-dihydroxycyclohexa-1,5-dienecarbonyl-CoA + NADPH <=> trans-4,5-dihydroxycyclohexa-2-enecarbonyl-CoA + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
gama-chloro-beta-methylcrotonyl-[acyl-carrier-protein] + NADPH + H+ <=> gama-chloro-beta-methylbutanoyl-[acyl-carrier-protein] + NADP+ 1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
–
bis-gamma-glutamylcystine + NADPH + H+ <=> gamma-glutamyl_cystine + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
Hordeum_vulgare_thioredoxin_2_mutant_G47P + NADP+ <=> Hordeum_vulgare_thioredoxin_2_mutant_G47P_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
methylthioalkyl_glucosinolate + NADPH + H+ + O2 <=> methylsulfinylalkyl_glucosinolate_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
pyruvate + ethylamine + NADPH + H+ <=> N-ethyl-L-alanine + NADP+ 1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
L-lysine + NADPH + H+ + O2 <=> N5-hydroxy-L-lysine + NADP+ + H2O 1.14.13.195 L-ornithine N5-monooxygenase (NADPH)
–
2-Hydroxy-1,4-naphthoquinone + NADPH + H+ <=> naphthalene-1,2,4-triol + NADP+ 1.6.5.5 NADPH:quinone reductase
–
Pargyline + NADPH + H+ + O2 <=> pargyline_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
NADPH + H+ + oxidized_5-cyano-2,3-ditolyl_tetrazolium_chloride <=> NADP+ + reduced_5-cyano-2,3-ditolyl_tetrazolium_chloride 1.6.2.4 NADPH---hemoprotein reductase
–
NADPH + H+ + oxidized_CYP106A1 <=> NADP+ + reduced_CYP106A1 1.6.2.4 NADPH---hemoprotein reductase
–
NADPH + H+ + oxidized_CYP21A2 <=> NADP+ + reduced_CYP21A2 1.6.2.4 NADPH---hemoprotein reductase
–
NADPH + H+ + oxidized_eburicol <=> NADP+ + reduced_eburicol 1.6.2.4 NADPH---hemoprotein reductase
–
NADPH + H+ + oxidized_lanosterol <=> NADP+ + reduced_lanosterol 1.6.2.4 NADPH---hemoprotein reductase
–
NADPH + H+ + oxidized_tetrazolium <=> NADP+ + reduced_tetrazolium 1.6.2.4 NADPH---hemoprotein reductase
–
NADPH + H+ + oxidized_thiazolyl_blue_tetrazolium_bromide <=> NADP+ + reduced_thiazolyl_blue_tetrazolium_bromide 1.6.2.4 NADPH---hemoprotein reductase
–
reduced_tissue_factor + NADP+ <=> tissue_factor + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
–
seleno-L-methionine + NADPH + H+ + O2 <=> seleno-L-methionine_Se-oxideoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
Nicotine + NADPH + H+ <=> Nornicotine + NADP+ 1.14.14.B11
–
Prostaglandin_B1 + NADP+ <=> 15-ketoprostaglandin_B1 + NADPH + H+ 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
–
–
progesterone + NADPH <=> 3alpha-hydroxy-4-pregnen-20-one + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
–
3,8-divinyl_chlorophyll_a + NADPH + H+ <=> 3-vinyl-chlorophyll_a + NADP+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
divinyl_protochlorophyllide_a + NADPH + H+ <=> 3-vinyl-protochlorophyllide_a + NADP+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
oxidized_Clostridium_pasteurianum_rubredoxin + NADPH <=> reduced_Clostridium_pasteurianum_rubredoxin + NADP+ + H+ 1.18.1.4 rubredoxin---NAD(P)+ reductase
–
oxidized_flavodiiron_protein + NADPH <=> reduced_flavodiiron_protein + NADP+ + H+ 1.18.1.4 rubredoxin---NAD(P)+ reductase
–
oxidized_Pyrococcus_furiosus_rubredoxin + NADPH <=> reduced_Pyrococcus_furiosus_rubredoxin + NADP+ + H+ 1.18.1.4 rubredoxin---NAD(P)+ reductase
–
oxidized_rubrerythrin + NADPH <=> reduced_rubrerythrin + NADP+ + H+ 1.18.1.4 rubredoxin---NAD(P)+ reductase
–
[redox_protein_PhRP]-disulfide + NADPH + H+ <=> [redox_protein_PhRP]-dithiol + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
[thioredoxin_reductase_from_Escherichia_coli]-disulfide + NADPH + H+ <=> [thioredoxin_reductase_from_Escherichia_coli]-dithiol + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
1-(4''-sulfophenylazo)-2-hydroxy-6-sulfonaphthalene + NADPH <=> Sulfanilic_acid + NADP+ + 1-amino-2-hydroxy-6-sulfonaphthalene 1.7.1.6 azobenzene reductase
–
4-[(4-hydroxy-1-naphthalenyl)azo]benzene_sulfonic_acid + NADH <=> Sulfanilic_acid + 4-amino-1-naphthol + NADP+ 1.7.1.6 azobenzene reductase
–
4-[(4-hydroxy-1-naphthalenyl)azo]benzene_sulfonic_acid + NADPH <=> Sulfanilic_acid + 4-amino-1-naphthol + NADP+ 1.7.1.6 azobenzene reductase
–
1-(4''-sulfophenylazo)-2-hydroxy-6-carboxynaphthalene + NADPH <=> Sulfanilic_acid + NADP+ + 1-amino-2-hydroxy-6-carboxynaphthalene 1.7.1.6 azobenzene reductase
–
2-aminopentanoate + H2O + NADP+ <=> 2-Oxopentanoate + NH3 + NADPH + H+ 1.4.1.4 glutamate dehydrogenase (NADP+)
–
Pyridine-4-aldehyde + NADPH <=> 4-hydroxypyridine + NADP+ 1.1.1.21 aldose reductase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
4-hydroxypyridine + NADP+ <=> 4-pyridone + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
cyclodecanone + NADPH + O2 <=> 1-oxa-2-oxocycloendecane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
Fe(III)-citrate + NADPH <=> Fe(III)-citrate + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
–
2-hydroxyethyl_methyl_sulfide + NADPH + O2 <=> 2-hydroxyethyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
3,6-dideoxy-beta-D-galactofuranose + NADP+ <=> 3,6-dideoxy-D-galactono-1,4-lactone + NADPH 1.1.1.120 galactose 1-dehydrogenase (NADP+)
–
D-allose + NADP+ <=> D-allono-1,5-lactone + NADPH 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
3beta,17beta-dihydroxy-androst-5-en-16-one + NADPH <=> 3beta,16alpha,17beta-trihydroxyandrost-5-ene + NADP+ 1.1.1.147 16alpha-hydroxysteroid dehydrogenase
–
trans-4-hydroxy-2-alkenal + NADPH <=> 4-hydroxyalkanal + NADP+ 1.3.1.74 2-alkenal reductase [NAD(P)+]
–
4-hydroxy-2-hexenal + NADPH <=> 4-hydroxyhexenal + NADP+ 1.3.1.74 2-alkenal reductase [NAD(P)+]
–
oxidized_2,6-dichlorophenolindophenol + NADP+ <=> reduced_2,6-dichlorophenolindophenol + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
a_very-long-chain_trans-2,3-dehydroacyl-CoA + NADPH + H <=> behenoyl-CoA + NADP+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
B
K3Fe(CN)6 + NADPH <=> K4Fe(CN)6 + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
magnesium-mesoporphyrin_IX + NADPH + O2 <=> diethyl_protochlorophyllide + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
reduced_flavodoxin_mutant_I59A/I92A + NADP+ <=> oxidized_flavodoxin_mutant_I59A/I92A + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
reduced_flavodoxin_mutant_I59E/I92E + NADP+ <=> oxidized_flavodoxin_mutant_I59E/I92E + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
reduced_flavodoxin_mutant_I59A + NADP+ <=> oxidized_flavodoxin_mutant_I59A + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
reduced_flavodoxin_mutant_I92E + NADP+ <=> oxidized_flavodoxin_mutant_I92E + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
reduced_flavodoxin_mutant_I92A + NADP+ <=> oxidized_flavodoxin_mutant_I92A + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
reduced_flavodoxin_mutant_W57E + NADP+ <=> oxidized_flavodoxin_mutant_W57E + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
reduced_flavodoxin_mutant_W57R + NADP+ <=> oxidized_flavodoxin_mutant_W57R + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
reduced_flavodoxin_mutant_W57K + NADP+ <=> oxidized_flavodoxin_mutant_W57K + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
reduced_flavodoxin_mutant_I59E + NADP+ <=> oxidized_flavodoxin_mutant_I59E + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
reduced_ferredoxin_II + NADP+ <=> oxidized_ferredoxin_II + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
–
2,5-hexanedione + NADP+ <=> (2S,5S)-hexanediol + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-Methylacetoacetate + NADPH + H+ <=> (2R,3S)-3-hydroxy-2-methylbutanoate + NADP+ 1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
–
(S)-beta-hydroxyisobutyrate + NADP+ <=> 2-Methyl-3-oxopropanoate + NADPH + H+ 1.1.1.31 3-hydroxyisobutyrate dehydrogenase
–
1,2-dimethylhydrazine + NADPH + H+ + O2 <=> 1,2-dimethylhydrazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
1-methyl-2-benzylhydrazine + NADPH + H+ + O2 <=> 1-methyl-2-benzylhydrazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
3''-trifluoro-acetophenone + NADPH + H+ <=> 1-[(3''-trifluoro)phenyl]ethanol + NADP+ 1.1.1.B4
–
10-(N,N-dimethylaminooctyl)2-(trifluoromethyl)phenothiazine + NADP+ + H2O <=> 10-(N,N-dimethylaminooctyl)2-(trifluoromethyl)phenothiazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
15-deoxy-DELTA12,14-prostaglandin_J2 + NADPH + H+ <=> 12,13-dihydro-15-deoxy-DELTA12,14-prostaglandin_J2 + NADP+ 1.3.1.74 2-alkenal reductase [NAD(P)+]
–
17alpha,21-dihydroxy-5beta-pregnan-3,20-dione + NADPH + H+ <=> 17alpha,20alpha,21-trihydroxy-5beta-pregnane-3-one + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
3-phenylpropanal + NADPH + H+ <=> 3-phenylpropionyl_alcohol + NADP+ 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
5-hydroxyphenylpyruvate + NADPH + H+ <=> 5-hydroxyphenyllactate + NADP+ 1.1.1.237 hydroxyphenylpyruvate reductase
–
5alpha-pregnan-20alpha-ol-3-one + NADP+ <=> 5alpha-pregnan-20alpha,3alpha-diol + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
benzylhydrazine + NADPH + H+ + O2 <=> benzylhydrazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
Phenelzine + NADPH + H+ + O2 <=> beta-ethylphenylhydrazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
butylhydrazine + NADPH + H+ + O2 <=> butylhydrazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
acetoacetyl-N-acetylcysteamine + NADPH + H+ <=> D-3-hydroxybutyryl-N-acetylcysteamine + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
acetoacetyl-pantetheine + NADPH + H+ <=> D-3-hydroxybutyryl-pantetheine + NADP+ 1.1.1.36 acetoacetyl-CoA reductase
–
ethylhydrazine + NADPH + H+ + O2 <=> ethylhydrazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
NADPH + thio-NADP+ <=> NADP+ + H+_thio-NADPH 1.8.1.12 trypanothione-disulfide reductase
–
Hordeum_vulgare_thioredoxin_disulfide_h1 + NADPH + H+ <=> Hordeum_vulgare_thioredoxin_h1 + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
Hordeum_vulgare_thioredoxin_disulfide_h2 + NADPH + H+ <=> Hordeum_vulgare_thioredoxin_h2 + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
isopropylhydrazine + NADPH + H+ + O2 <=> isopropylhydrazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
mitochondrial_thioredoxin + NADP+ <=> mitochondrial_thioredoxin_disulfide + NADPH 1.8.1.B1
–
N-aminomorpholine + NADPH + H+ + O2 <=> N-aminomorpholine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
N-aminopyrrolidine + NADPH + H+ + O2 <=> N-aminopyrrolidine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
isopropylhydrazine + NADPH + H+ + O2 <=> N-propylhydrazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
phenylhydrazine + NADPH + H+ + O2 <=> phenylhydrazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
procarbazine + NADPH + H+ + O2 <=> procarbazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
oxidized_3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium + NADPH + H+ <=> reduced_3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
oxidized_ferredoxin_II_mutant_D64N + NADPH + H+ <=> reduced_ferredoxin_II_mutant_D64N + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
–
oxidized_ferredoxin_II_mutant_Q39R/S28E + NADPH + H+ <=> reduced_ferredoxin_mutant_Q39R/S28E + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
–
NADPH + H+ + oxidized_nitroblue_tetrazolium_hydrochloride <=> NADP+ + reduced_nitroblue_tetrazolium_hydrochloride 1.6.99.1 NADPH dehydrogenase
–
sodium_D-glucuronate + NADPH + H+ <=> sodium_L-gulonate + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
fluorene + NADPH + H+ + O2 <=> 9-fluorenol + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
cyclolaudenone + NADPH <=> cyclolaudenol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
(6E)-8-oxogeranial + NADPH + H+ <=> (R)-8-oxocitronellal + (S)-8-oxocitronellal + NADP+ 1.3.1.123 8-oxogeranial reductase
–
(6E)-8-oxogeranial + NADPH + H+ <=> cis-trans-nepetalactone + NADP+ 1.3.1.122 (S)-8-oxocitronellyl enol synthase
–
DL-mevalonate_CoA + NADP+ <=> 3-hydroxy-3-methylglutaryl-CoA + NADPH + H+ 1.1.1.88 hydroxymethylglutaryl-CoA reductase
–
(6E)-8-oxogeranial + NADPH + H+ <=> trans-cis-nepetalactone + NADP+ 1.3.1.122 (S)-8-oxocitronellyl enol synthase
–
androstenone + NADPH + H+ <=> 5alpha-androst-16-en-3beta-ol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
8-nitroguanine + NADPH <=> 8-aminoguanine + NADP+ + H2O 1.8.1.4 dihydrolipoyl dehydrogenase
–
dihydromyricetin + NADPH <=> gallocatechin + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
–
1,3-dihydroxynaphthalene + NADPH + H+ <=> deshydroxyvermelone + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
triangularine + NADPH + O2 <=> triangularine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
axillarine + NADPH + O2 <=> axillarine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
heliotrine + NADPH + O2 <=> heliotrine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
lycopsamine + NADPH + O2 <=> lycopsamine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
monocrotaline + NADPH + O2 <=> monocrotaline_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
seneciphylline + NADPH + O2 <=> seneciphylline_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
retrorsine + NADPH + O2 <=> retrorsine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
senecivernine + NADPH + O2 <=> senecivernine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
axillaridine + NADPH + O2 <=> axillaridine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
rinderine + NADPH + O2 <=> rinderine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
indicine + NADPH + O2 <=> indicine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
(2E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one + NADPH <=> (o-hydroxybenzyl)acetophenone + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
Methyl_red + NADPH <=> 2-[4-(dimethylamino)phenylazo]benzoic_acid + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
3-phenyl-2-butanone + NADPH + H+ + O2 <=> (RS)-1-phenylethyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
palmitate + NADPH + H+ + O2 <=> 16-hydroxypalmitic_acid + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
Dimethyl_ether + NADPH + O2 <=> methanol + formaldehyde + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
methyl_tert-butyl_ether + NADPH + H+ + O2 <=> tert-butanol + NADP+ + H2O + methanol 1.14.15.3 alkane 1-monooxygenase
–
NADP+ + nicotinate <=> nicotinate-adenine_dinucleotide_phosphate 3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
–
pheophorbide_a + NADPH + H+ + O2 <=> red_chlorophyll_catabolite + NADP+ 1.14.15.17 pheophorbide a oxygenase
–
acenaphthenequinone + NADPH <=> NADP+ + acenaphthylene-1,2-diol 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.6 p-benzoquinone reductase (NADPH)
–
–
isatin + NADPH <=> NADP+ + 1-methyl-1H-indole-2,3-diol 1.6.5.6 p-benzoquinone reductase (NADPH)
–
dihydro-4-methyl-4-propyl-2,3-furanedione + NADPH <=> NADP+ + 4-methyl-4-propyl-4,5-dihydrofuran-2,3-diol 1.6.5.6 p-benzoquinone reductase (NADPH)
–
dihydro-5-isopropyl-4,4-dimethyl-2,3-furanedione + NADPH <=> NADP+ + 5-isopropyl-4,4-dimethyl-4,5-dihydrofuran-2,3-diol 1.6.5.6 p-benzoquinone reductase (NADPH)
–
dihydro-5-(3-pentyl)-4,4-dimethyl-2,3-furanedione + NADPH <=> NADP+ + 5-(1-ethylpropyl)-4,4-dimethyl-4,5-dihydrofuran-2,3-diol 1.6.5.6 p-benzoquinone reductase (NADPH)
–
dihydro-5-(2-pentyl)-4,4-dimethyl-2,3-furanedione + NADPH <=> NADP+ + 4,4-dimethyl-5-(1-methylbutyl)-4,5-dihydrofuran-2,3-diol 1.6.5.6 p-benzoquinone reductase (NADPH)
–
dihydro-5-(2-pentyl)-4-methyl-4-propyl-2,3-furanedione + NADPH <=> NADP+ + 4-methyl-5-(1-methylbutyl)-4-propyl-4,5-dihydrofuran-2,3-diol 1.6.5.6 p-benzoquinone reductase (NADPH)
–
dihydro-5-(2-butyl)-4-methyl-4-ethyl-2,3-furanedione + NADPH <=> NADP+ + 5-sec-butyl-4-ethyl-4-methyl-4,5-dihydrofuran-2,3-diol 1.6.5.6 p-benzoquinone reductase (NADPH)
–
ethyl_benzoylformate + NADPH + H+ <=> ethyl-(S)-mandelate + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
1.1.1.B4
–
–
pyridoxine_5'-phosphate + NADP+ <=> pyridoxal_5''-phosphate + NADPH 1.1.1.65 pyridoxine 4-dehydrogenase
–
TDP-6-deoxy-D-xylo-4-hexosulose + NADPH <=> dTDP-6-deoxy-beta-L-talose + NADP+ 1.1.1.134 dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+)
–
4-chloronitrobenzene + 2 NADPH + 2 H+ <=> 2-amino-5-chlorophenol + 2 NADP+ + H2O 1.7.1.16 nitrobenzene nitroreductase
–
oracin + NADPH <=> (+)-6-[2-(2-hydroxyethyl)aminoethyl]-5-oxo-11-hydroxy-5,6-dihydro-11H-indeno[1,2-c]isoquinoline + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
4-amino-2,6-dichlorophenol + NADPH + O2 <=> 2,6-dichlorohydroquinone + NADP+ + hydroxylamine 1.14.13.50 pentachlorophenol monooxygenase
–
5,5''-dithiobis(2-nitrobenzoic_acid) + NADPH <=> 4-nitrothiophenolate + NADP+ 1.8.1.13 bis-gamma-glutamylcystine reductase
–
3alpha,5alpha,_20alpha-trihydroxyprogesterone + NADP+ <=> 5alpha,_20alphy-dihydroxyprogesterone-3-one + NADPH 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
(+)-costunolide + NADPH <=> 11(S),13-dihydrocostunolide + NADP+ 1.3.1.31 2-enoate reductase
–
phenylacylbromide + NADPH <=> (R)-2-bromo-1-phenylethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
5-methyl-trans-trans-2,4-hexadienoyl-CoA + NADPH <=> 5-methyl-trans-3-hexenoyl-CoA + NADP+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
5alpha-dihydroprogesterone + NADPH <=> 5alpha-hydroxy-pregnan-20-one + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
5alpha-pregnane-21-ol-3,20-dione + NADPH <=> 5alpha-pregnane-20alpha,21-diol-3-one + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
5alpha-Pregnan-3alpha,21-diol-20-one + NADPH + H+ <=> 5alpha-pregnane-3alpha,20alpha,21-triol + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
3-carboxybenzaldehyde + NADP+ + H2O <=> isophthalate + NADPH + H+ 1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
glutathione-S-4-oxonon-2-enal + NADPH <=> S-(1-hydroxy-4-oxonona-3-yl)glutathione + NADP+ 1.1.1.21 aldose reductase
–
nonanophenone + NADPH <=> 1-phenylnonan-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Prostaglandin_D2 + NADPH <=> 9alpha,11beta-prostaglandin_F2alpha + NADP+ 1.1.1.188 prostaglandin-F synthase
–
prostaglandin_D2_ethanolamide + NADPH <=> prostaglandin_9alpha,11beta-F2_ethanolamide + NADP+ 1.1.1.188 prostaglandin-F synthase
–
Pyridine-3-aldehyde + NADPH <=> pyridin-3-ylbutanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Pyridine-4-aldehyde + NADPH <=> pyridin-4-ylbutanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
valerophenone + NADPH <=> 1-phenylpentan-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
4-Chloro-2-nitrophenol + NADPH + O2 <=> 4-Chlorocatechol + NADP+ + H2O 1.14.13.31 2-nitrophenol 2-monooxygenase
–
NH3 + NADPH + O2 <=> hydroxylamine + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
selegiline + NADPH + O2 <=> selegiline_N-oxide + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
1,3-dithiane + NADPH + O2 <=> (R)-1,3-dithiane-1-oxide + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
1,4-Naphthoquinone + NADPH <=> 1,4-naphthohydroquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
1,8-dihydroxy-9,10-anthraquinone + NADPH <=> 1,8-dihydroxy-9,10-anthraquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
1-hydroxy-9,10-anthraquinone + NADPH <=> 1-hydroxy-9,10-anthraquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
17beta-estradiol + NADPH + H+ + O2 <=> 1,3,5(10)-estratrien-3,7-alpha,17beta-triol + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
2,3-diglutathionyl-1,4-naphthoquinone + NADPH <=> 2,3-diglutathionyl-1,4-naphthoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2,5-bis(ethylamino)-3,6-di(aziridinyl)-1,4-benzoquinone + NADPH <=> 2,5-bis(ethylamine)-3,6-diaziridinyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2,5-dihydroxy-1,4-naphthoquinone + NADPH <=> 2,5-dihydroxy-1,4-naphthoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2,5-dimethyl-1,4-naphthoquinone + NADPH <=> 2,5-dimethyl-1,4-naphthoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-decanone + NADPH + H+ + O2 <=> methyl_nonanoate + NADP+ + H2O 1.14.13.226 acetone monooxygenase (methyl acetate-forming)
–
2-methyl-3-glutathionyl-5-hydroxy-1,4-naphthoquinone + NADPH <=> 2-methyl-3-glutathionyl-5-hydroxy-1,4-naphthoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-hydroxy-3-methyl-1,4-naphthoquinone + NADPH <=> 2-methyl-3-hydroxy-1,4-naphthoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-methyl-5-aziridinyl-1,4-benzoquinone + NADPH <=> 2-methyl-5-aziridinyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
22-hydroxycholesterol + NADPH + H+ + O2 <=> 7alpha,22-dihydroxycholesterol + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
24,25-epoxycholesterol + NADPH + H+ + O2 <=> 7alpha,hydroxy-24,25-epoxycholesterol + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
3,4-cis-leucodelphinidin + NADPH <=> 2,3-trans-gallocatechin + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
–
cis-3,4-leucopelargonidin + NADPH <=> 2,3-trans-afzelechin + NADP+ + H2O 1.17.1.3 leucoanthocyanidin reductase
–
4-acetoxycyclohexanone + NADPH + H+ + O2 <=> 5-acetoxyoxepan-2-one + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
–
4-allyloxycyclohexanone + NADPH + H+ + O2 <=> 5-allyloxyoxepan-2-one + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
–
4-androstene-3,17-dione + NADPH + H+ + O2 <=> 7alpha-hydroxy-4-androstene-3,17-dione + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
4-benzyloxycyclohexanone + NADPH + H+ + O2 <=> 5-benzyloxyoxepan-2-one + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
–
4-chlorocyclohexanone + NADPH + H+ + O2 <=> 5-chlorooxepan-2-one + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
4-ethoxycyclohexanone + NADPH + H+ + O2 <=> 5-ethoxyoxepane-2-one + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
4-Heptanone + NADPH + O2 <=> propanyl_butanoate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
bicyclo[3.2.0]hept-2-en-6-one + NADPH + O2 <=> 3-oxabicyclo[3.3.0]oct-6-en-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
bicyclohept-2-en-6-one + NADPH + O2 <=> 3-oxabicyclo[3.3.0]oct-6-en-2-one + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
bupivacaine + NADPH + O2 <=> bupivacaine-oxide + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
chlortetracycline + NADPH + H+ + O2 <=> 11a-hydroxy-chlortetracycline + NADP+ + H2O 1.14.13.231 tetracycline 11a-monooxygenase
–
demeclocycline + NADPH + H+ + O2 <=> 11a-hydroxy-demeclocycline + NADP+ + H2O 1.14.13.231 tetracycline 11a-monooxygenase
–
doxycycline + NADPH + H+ + O2 <=> 11a-hydroxy-doxycycline + NADP+ + H2O 1.14.13.231 tetracycline 11a-monooxygenase
–
hexahydro-1,3,5-trinitro-1,3,5-triazine + NADPH <=> hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine + NADP+ 1.7.1.2 nitrate reductase [NAD(P)H]
–
lidocaine + NADPH + O2 <=> lidocaine-oxide + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
minocycline + NADPH + H+ + O2 <=> 11a-hydroxy-minocycline + NADP+ + H2O 1.14.13.231 tetracycline 11a-monooxygenase
–
p-tolyl_sulfide + NADPH + O2 <=> p-tolyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
Picolinic_acid + NADP+ + H2O <=> 6-hydroxypicolinic_acid + NADP+ 1.17.1.5 nicotinate dehydrogenase
–
propranolol + NADPH + O2 <=> propranolol-hydroxylamine + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
pyrazoloacridine + NADPH + O2 <=> pyrazoloacridine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
cinnamaldehyde + NADPH <=> cinnamaldehyde + NADP+ 1.3.1.27 2-hexadecenal reductase
–
NADPH + H+ + 2,3-dichloro-5,6-dicyano-1,4-benzoquinone <=> NADP+ + 2,3-dichloro-5,6-dicyano-1,4-benzoquinol 1.6.5.10 NADPH dehydrogenase (quinone)
–
3-nitro-L-tyrosine + NADPH <=> 3-Aminotyrosine + NADP+ + H2O 1.8.1.4 dihydrolipoyl dehydrogenase
–
3-oxohexanoyl-CoA + NADPH <=> 3-hydroxyhexanoyl-CoA + NADP+ 1.1.1.36 acetoacetyl-CoA reductase
–
Indole-3-acetaldehyde + NADPH <=> 3-hydroxyindole + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Indole-3-aldehyde + NADPH <=> 3-hydroxyindole + NADP+ 1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
–
picolinaldehyde + NADPH <=> 3-Pyridylcarbinol + NADP+ 1.1.1.21 aldose reductase
–
4,4-gem-dimethyl-5alpha-cholest-7-en-3-one + NADPH <=> 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
S-adenosyl-L-methionine + NADPH + formate_acetyltransferase-glycine <=> 5''-deoxyadenosine + L-methionine + NADP+ + formate_acetyltransferase-glycine-2-yl-radical 1.97.1.4 [formate-C-acetyltransferase]-activating enzyme
–
1-(4''-sulfonaminophenylazo-)2-naphthol + NADPH <=> sulfanilamide + NADP+ + 1-amino-2-hydroxynaphthalene 1.7.1.6 azobenzene reductase
–
cyclooctane + NADPH + H+ + O2 <=> Cyclooctanol + NADP+ + H2O 1.14.15.3 alkane 1-monooxygenase
–
1-phenyl-1,2-propanedione + NADPH + H+ <=> (R)-2-hydroxy-1-phenyl-propanone + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
11beta-hydroxy-pregn-4-ene-3,20,21-trione + NADPH <=> corticosterone + NADP+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
dehydrocorticosterone + NADPH <=> corticosterone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
corticosterone + NADP+ <=> 21-hydroxy-pregn-4-en-3,11,20-trione + NADPH 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
L-methionine_(S)-sulfoxide + NADPH + H+ <=> L-methionine + NADP+ + H2O 1.8.4.13 L-methionine (S)-S-oxide reductase
–
methionine_sulfoxide + NADPH <=> L-methionine + NADP+ + H2O 1.8.4.13 L-methionine (S)-S-oxide reductase
–
ethyl_tert-butyl_ether + NADPH + H+ + O2 <=> tert-butanol + NADP+ + H2O + acetaldehyde 1.14.15.3 alkane 1-monooxygenase
–
nalorphine + NADP+ <=> (5alpha)-3-hydroxy-17-(prop-2-en-1-yl)-7,8-didehydro-4,5-epoxymorphinan-6-one + NADPH + H+ 1.1.1.218 morphine 6-dehydrogenase
–
3-oxofumonisin_B3 + NADPH <=> fumonisin_B3 + NADP+ 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
–
9-(phenylcarbonyl)-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-one + NADPH <=> 9-[hydroxy(phenyl)methyl]-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-one + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
Prednisone + NADPH <=> Prednisolone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
1,2-dehydrocortisone + NADPH <=> Prednisolone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
prostaglandin_D1 + NADP+ <=> 15-ketoprostaglandin_D1 + NADPH + H+ 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
–
3alpha-hydroxypregn-4-en-20-one + NADP+ <=> progesterone + NADPH + H+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
3''-methylacetophenone + NADPH + H+ <=> 1-(3''-methylphenyl)ethanol + NADP+ 1.1.1.B4
–
4-acetylpyridine + NADPH <=> 1-(4-pyridinyl)-1-ethanol + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
1-(4-pyridyl)acetone + NADPH + H+ <=> 1-(4-pyridinyl)-1-ethanol + NADP+ 1.1.1.B4
–
acetaldehyde + NADP+ + H2O <=> succinate + NADPH + H+ 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
–
17beta-hydroxyestra-4-en-3-one + NADP+ <=> 4-estrene-3,17-dione + NADPH + H+ 1.1.1.62 17beta-estradiol 17-dehydrogenase
–
1,5-anhydro-3-keto-D-fructose + NADP+ <=> 1,5-anhydro-D-mannitol + NADPH 1.1.1.263 1,5-anhydro-D-fructose reductase
–
3-hydroxy-2-methylpropanoate + NADP+ <=> 2-Methyl-3-oxopropanoate + NADPH + H+ 1.1.1.31 3-hydroxyisobutyrate dehydrogenase
–
D-galactosone + NADP+ <=> D-talose + NADPH 1.1.1.263 1,5-anhydro-D-fructose reductase
–
ethyl_3,3-dimethyl-2-oxobutyrate + NADPH + H+ <=> ethyl_(R)-2-hydroxy-3,3-dimethylbutyrate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
ethyl_3-methyl-2-oxobutyrate + NADPH + H+ <=> ethyl_(R)-2-hydroxy-3-methylbutyrate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
dCTP + NAD+ <=> dCDP + NADP+ 2.7.1.23 NAD+ kinase
–
ethyl_4,4,4-trifluoro-3-oxobutanoate + NADPH + H+ <=> ethyl_(3S)-4,4,4-trifluoro-3-hydroxybutyrate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
(-)-menthone + NADPH <=> (3S)-neomenthol + NADP+ 1.1.1.208 (+)-neomenthol dehydrogenase
–
4-benzoylpyridine + NADPH <=> (S)-alpha-phenyl-4-pyridylmethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
1-adamantyl_methyl_ketone + NADPH + H+ <=> 1-adamantyl_methyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
11-deoxycorticosterone + NADPH <=> 4-pregnen-20alpha,21-diol-3-one + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
2''-methoxyacetophenone + NADPH + H+ <=> 1-(2-methoxyphenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2,2-dimethylcyclohexanone-1,3-dione + NADPH + H+ <=> (S)-3-hydroxy-2,2-dimethylcyclohexanone + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2,2-dimethylpropiophenone + NADPH + H+ <=> 2,2-dimethylpropiophenol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2,4-octanedione + NADPH + H+ <=> (S)-2-hydroxy-4-octanone + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
1-(3-bromophenyl)ethanol + NADP+ <=> 3'-bromoacetophenone + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.B4
–
–
1-(3-chlorophenyl)ethanol + NADP+ <=> 3'-chloroacetophenone + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.B4
–
–
corticosterone + NADPH <=> 4-pregnen-11beta,20alpha,21-triol-3-one + NADP+ 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
chloromethyl_3-oxobutyrate + NADPH + H+ <=> chloromethyl_(S)-3-hydroxybutyrate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
dehydroepiandrosterone + NADPH <=> 5-androstene-3alpha,17alpha-diol + NADP+ 1.1.1.148 estradiol 17alpha-dehydrogenase
–
a_dihydroflavonol + NADPH <=> flavan-3,4-diol + NADP+ 1.1.1.219 dihydroflavonol 4-reductase
–
ethyl_(R)-2-hydroxy-3,3-dimethylbutyrate + NADPH + H+ <=> ethyl_3,3-dimethyl-2-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
ethyl_4,4-dimethyl-3-oxopentanoate + NADPH + H+ <=> ethyl_4,4-dimethyl-3-hydroxypentanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
isopropyl_3-oxobutyrate + NADPH + H+ <=> isopropyl_(S)-3-hydroxybutyrate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
N-propylyl-4-piperidone + NADPH <=> N-propylpiperidinol + NADP+ 1.1.1.206 tropinone reductase I
–
phenyl_3-oxobutyrate + NADPH + H+ <=> phenyl_(S,R)-3-hydroxybutyrate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
1-phenyl-1,2-propanedione + NADPH <=> phenylpropan-2,3-diol + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
tert-butyl_3-oxobutanoate + NADPH + H+ <=> tert-butyl_(S)-3-hydroxybutyrate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
4-ethylcyclohexanone + NADPH + O2 + H+ <=> (5S)-5-ethyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
4-methylcyclohexanone + NADPH + O2 + H+ <=> (5S)-5-methyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
3-methylcyclohexanone + NADPH + O2 + H+ <=> (4S)-4-methyloxepan-2-one + (6R)-6-methyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
an_arylamine + NADP+ + H2O <=> an_aromatic_hydroxylamine + NADPH + H+ 1.7.1.B2
1.7.1.B3
–
–
an_arylamine + 3 NADP+ + 2 H2O <=> an_aromatic_nitrate + 3 NADPH + 3 H+ 1.7.1.B2
1.7.1.B3
–
–
4a-methyltetrahydro-1aH-naphtho[1,8a-b]oxirene-2,5(3H,6H)-dione + NADPH + O2 <=> (1R,3S,7S)-7-methyl-2,8-dioxatricyclo[5.5.0.01,3]dodecane-4,9-dione + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
(1R,5S)-8-oxabicyclo[3.2.1]oct-6-en-3-one + NADPH + O2 <=> (1S,6S)-3,9-dioxabicyclo[4.2.1]non-7-en-4-one + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
–
linoleic_acid + NADPH + O2 <=> crepenynate + NADP+ + H2O 1.14.19.39 acyl-lipid Delta12-acetylenase
–
thiosulfate + NADPH <=> Sulfide + NADP+ + sulfite 2.8.1.5 thiosulfate---dithiol sulfurtransferase
–
dGTP + NAD+ <=> dGDP + NADP+ 2.7.1.23 NAD+ kinase
–
3,4-dihydronaphthalen-2(1H)-one + NADPH + H+ + O2 <=> 4,5-dihydro-3-benzoxepin-2(1H)-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
1,4-dioxaspiro[4.5]decan-8-one + NADPH + H+ + O2 <=> 1,4,8-trioxaspiro[4.6]undecan-9-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
octahydronaphthalen-2(1H)-one + NADPH + O2 + H+ <=> octahydro-3-benzoxepin-2(1H)-one + octahydro-2-benzoxepin-3(1H)-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
Glutaraldehyde + NADP+ + H2O <=> Glutarate + NADPH + H+ 1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
–
–
1-(2-pyridyl)acetone + NADPH + H+ <=> (S)-1-(2-pyridyl)ethanol + NADP+ 1.1.1.B4
–
4-tert-butylcyclohexanone + NADPH + O2 + H+ <=> (5S)-5-tert-butyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
(3R)-3-(1-methylethenyl)cyclohexanone + NADPH + O2 + H+ <=> (6S)-6-(1-methylethenyl)oxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
2-hydroxycyclobutanone + NADPH + H+ + O2 <=> alpha-hydroxy-gamma-butyrolactone + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
2-deoxy-3-oxo-6-phosphogluconate + NADP+ <=> 1-deoxyribulose_5-phosphate + CO2 + NADPH 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
–
arachidonic_acid + NADPH + H+ + O2 <=> 20-hydroxyeicosatetraenoic_acid + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
1.14.15.3 alkane 1-monooxygenase
–
–
Pyridine-3-aldehyde + NADPH <=> 3-hydroxypyridine + NADP+ 1.1.1.19 glucuronate reductase
1.1.1.21 aldose reductase
1.1.1.263 1,5-anhydro-D-fructose reductase
–
–
–
3-methyl-3-buten-1-ol + NADP+ <=> 3-methyl-3-butenal + NADPH 1.1.1.183 geraniol dehydrogenase (NADP+)
–
3alpha,7beta-dihydroxy-5beta-cholanoic_acid + NADP+ <=> 7-ketolithocholic_acid + NADPH 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
4-iodobenzaldehyde + NADP+ + H2O <=> 4-Iodobenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
4-pregnen-20alpha-ol-3-one + NADP+ <=> progesterone + NADPH + H+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
15-ketoprostaglandin_E2 + NADPH <=> (5Z)-11alpha-hydroxy-9,15-dioxoprost-5-enoate + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
10-N-(n-octylamino)-2-(trifluoromethyl)_phenothiazine + NADPH + O2 <=> 10-N-(n-octylamino)-2-(trifluoromethyl)_phenothiazine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
4-acetylpyridine + NADPH <=> (S)-1-(4-pyridyl)ethanol + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
amphetamine + NADPH + O2 <=> amphetamine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
cysteamine + NADPH + O2 <=> cysteamine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
demeton-O + NADPH + O2 <=> demeton-O_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
ethiofencarb + NADPH + O2 <=> ethiofencarb_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
(2R,6S)-2,6-dimethylcyclohexanone + NADPH + H+ + O2 <=> (3R,7S)-3,7-dimethyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
methiocarb + NADPH + O2 <=> methiocarb_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
octahydronaphthalen-1(2H)-one + NADPH + H+ + O2 <=> octahydro-1-benzoxepin-2(3H)-one + octahydro-2-benzoxepin-1(3H)-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
2-Phenylethylamine + NADPH + O2 <=> phenethylamine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2 ethynylbenzene + NADPH + 3 O2 <=> 2-ethynylphenol + 2-hydroxy-6-oxo-octa-2,4-dien-7-ynoic_acid + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
S-(2E,6E)-farnesyl-L-cysteine + NADPH + O2 <=> S-farnesylcysteine_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
thiacetazone + 2 NADPH + 2 H+ + 2 O2 <=> thiacetazone_carbodiimide + 2 NADP+ + 2 H2O 1.14.13.8 flavin-containing monooxygenase
–
tibolone + NADPH <=> 3-hydroxytibolone + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
tigecycline + NADPH + O2 <=> 11a-hydroxytigecycline + NADP+ + H2O 1.14.13.231 tetracycline 11a-monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
tyramine + NADPH + O2 <=> tyramine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
(2E,4E)-hexa-2,4-dienal + NADPH + H+ <=> (2E,4E)-6-hydroxyhexa-2,4-dienal + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
1-hydroxy-2-[2-(nitrooxy)ethyl]-1-oxo-2-(2,4,6-trinitro-3-(nitro[2-(nitrooxy)ethyl]amino)phenyl)diazanium + NADPH + H+ <=> reduced_1-hydroxy-2-[2-(nitrooxy)ethyl]-1-oxo-2-(2,4,6-trinitro-3-(nitro[2-(nitrooxy)ethyl]amino)phenyl)diazanium + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
11beta-hydroxyandrost-5-ene-3,17-dione + NADPH <=> 11beta,17beta-dihydroxyandrost-5-ene-3-one + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
17-(2-dimethylylamino)ethylamino-17-demethoxygeldanamycin + NADH + H+ <=> reduced_17-(2-dimethylylamino)ethylamino-17-demethoxygeldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
17-(2-dimethylylamino)ethylamino-17-demethoxygeldanamycin + NADPH + H+ <=> reduced_17-(2-dimethylylamino)ethylamino-17-demethoxygeldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
17-(2-pyrrolidin-1-yl)ethylamino-17-demethoxygeldanamycin + NADH + H+ <=> reduced_17-(2-pyrrolidin-1-yl)ethylamino-17-demethoxygeldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
17-(2-pyrrolidin-1-yl)ethylamino-17-demethoxygeldanamycin + NADPH + H+ <=> reduced_17-(2-pyrrolidin-1-yl)ethylamino-17-demethoxygeldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
17-(allylamino)-17-demethoxygeldanamycin + NADH + H+ <=> reduced_17-allylamino-17-demethoxygeldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
17-(allylamino)-17-demethoxygeldanamycin + NADPH + H+ <=> reduced_17-allylamino-17-demethoxygeldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
17-amino-17-demethoxygeldanamycin + NADH + H+ <=> reduced_17-amino-17-demethoxygeldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
17-amino-17-demethoxygeldanamycin + NADPH + H+ <=> reduced_17-amino-17-demethoxygeldanamycin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2,3-dihydroxy-5-methyl-1,4-benzoquinone + NADPH <=> 2,3-dihydroxy-5-methyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2-chloro-thioanisole + NADPH + H+ + O2 <=> 2-chlorophenyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
2-methylphenylcyclohexanone + NADPH + O2 <=> 7-benzyloxepan-2-one + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
3-chloro-thioanisole + NADPH + H+ + O2 <=> 3-chlorophenyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
4,5,6,7-tetranitro-1,3-dihydro-2H-benzimidazol-2-one + NADPH_+ <=> reduced_4,5,6,7-tetranitro-1,3-dihydro-2H-benzimidazol-2-one + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
4,5,6-trinitro-1,3-dihydro-2H-benzimidazol-2-one + NADPH_+ <=> reduced_4,5,6-trinitro-1,3-dihydro-2H-benzimidazol-2-one + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
4-allyl-cyclohexanone + NADPH + O2 <=> 4-allyl-hexano-6-lactone + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
4-(methylsulfanyl)aniline + NADPH + H+ + O2 <=> 4-aminophenyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-androstene-3,17-dione + NADPH <=> 5beta-androstan-3,15-dione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
4-bromocyclohexanone + NADPH + O2 <=> 4-bromo-hexano-6-lactone + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
1-chloro-4-(methylsulfanyl)benzene + NADPH + H+ + O2 <=> 4-chlorophenyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
4-cyano-thioanisole + NADPH + H+ + O2 <=> 4-cyanophenyl_methyl_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
4-ethylcyclohexanone + NADPH + O2 <=> 4-ethyl-hexano-6-lactone + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
4-iodocyclohexanone + NADPH + O2 <=> 4-iodo-hexano-6-lactone + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
4-methoxy-cyclohexanone + NADPH + O2 <=> 4-methoxy-hexano-6-lactone + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
4-n-propyl-cyclohexanone + NADPH + O2 <=> 4-n-propyl-hexano-6-lactone + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
4-phenylcyclohexanone + NADPH + O2 <=> 4-phenyl-hexano-6-lactone + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly-al + NADPH + H+ <=> Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala-al + NADPH + H+ <=> Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-al + NADPH + H+ <=> Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala-al + NADPH + H+ <=> Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp-al + NADPH + H+ <=> Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu-al + NADPH + H+ <=> Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys-al + NADPH + H+ <=> Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe-al + NADPH + H+ <=> Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly-al + NADPH + H+ <=> Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-oxobutyrate + methylamine + NADPH <=> N-methyl-2-aminobutanoate + NADP+ + H2O 1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
–
2-Oxohexanoate + methylamine + NADPH <=> N-methyl-2-aminohexanoate + NADP+ + H2O 1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
–
androst-5-ene-3,11,17-trione + NADPH <=> 17beta-hydroxyandrost-5-ene-3,11-dione + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
campestenone + NADPH <=> 5alpha-campestan-3-one + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
11-deoxycorticosterone + NADPH <=> 21-trihydroxy-5beta-pregnane-3,20-dione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
dehydroepiandrosterone + NADPH <=> androstene-3beta,17beta-diol + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
ethyl_5-aziridin-1-yl-2,4-dinitrobenzoate + NADPH_+ <=> reduced_ethyl_5-aziridin-1-yl-2,4-dinitrobenzoate + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
3-Fluoropyruvate + methylamine + NADPH <=> N-methylfluoroalanine + NADP+ + H2O 1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
–
Met-Val + NADPH + O2 <=> (L-Met-S-oxide)-Val + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
seleno-L-methionine + NADPH + O2 <=> L-methionine_seleno-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
mercaptoimidazole + NADPH + O2 <=> mercaptoimidazole_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
N-methyl-N,2,4,6-tetranitroaniline + NADPH_+ <=> reduced_N-methyl-N,2,4,6-tetranitroaniline + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
N-methyl-N,2,4-trinitroaniline + NADPH_+ <=> reduced_N-methyl-N,2,4-trinitroaniline + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
alpha-naphthylthiourea + NADPH + O2 <=> naphthylthiourea_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
Phenylthiourea + NADPH + O2 <=> phenylthiourea_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
S-farnesylcysteine_methyl_ester + NADPH + O2 <=> S-farnesylcysteine_S-oxide_methyl_ester + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
Thiourea + NADPH + O2 <=> thiourea_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
[7alpha,17alpha]-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one + NADPH <=> [7alpha,17alpha]-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-ol + NADP+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
pentane + NADPH + O2 <=> 1-Pentanol + 2-Pentanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
(-)-limonene + NADPH + O2 <=> (S)-perillyl_alcohol + NADP+ + H2O 1.14.14.52 (S)-limonene 7-monooxygenase
–
limonene + NADPH + H+ + O2 <=> (S)-perillyl_alcohol + NADP+ + H2O 1.14.13.161 (+)-camphor 6-exo-hydroxylase
–
Direct_blue_15 + NADPH <=> 3,3''-dimethoxybenzidine + 1-hydroxy-2,8-diamino-3,6-naphthalenedisulfonic_acid + NADP+ 1.7.1.6 azobenzene reductase
–
NADPH + H+ + 17-allylamino-demethoxygeldanamycin <=> NADP+ + reduced_17-allylamino-demethoxygeldanamycin 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
dexamethasone + NADP+ <=> 11-dehydromethasone + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
cyanidin + 2 NADPH + 2 H+ <=> epicatechin + (-)-epicatechin + 2 NADP+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
–
anthocyanidin + 2 NADPH + H+ <=> epicatechin + 2 NADP+ 1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
a_ketosteroid + NADPH + H+ + O2 <=> a_steroid_ester/lactone + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
–
5,10-methylenetetrahydropteroyltriglutamate + NADP+ <=> 5,10-Methenyltetrahydropteroyltriglutamate + NADPH 1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
–
5-(aziridin-1-yl)-2,4-dinitrobenzamide + NADPH <=> 5-(aziridin-1-yl)-4-hydroxylamino-2-benzamide + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
Vanillin + NADP+ + H2O <=> vanillic_acid + NADPH + 2 H+ 1.2.1.67 vanillin dehydrogenase
–
cis-2-Butene + NADPH + O2 <=> cis-2,3-Epoxybutane + cis-2-buten-1-ol + 2-butanone + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
ethyl_2-oxo-4-phenylbutanoate + NADPH + H+ <=> (+-)-2-hydroxy-4-phenylbutyric_acid_ethyl_ester + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
2-butanone + NADP+ <=> 2-butanol + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.4 (R,R)-butanediol dehydrogenase
–
–
(4S)-4,6-dihydroxy-2,5-dioxohexanoate + NADPH + H+ <=> 2-dehydro-3-deoxy-D-gluconate + NADP+ 1.1.1.127 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
–
loganin + NADPH + H+ + O2 <=> secologanin + NADP+ + 2 H2O 1.3.3.9 secologanin synthase
–
octan-3-one + NADPH + O2 <=> ethyl_hexanoate + pentyl_propanoate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
benzocyclobutanone + NADPH + O2 <=> 2-coumaranone + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
testosterone + NADPH + H+ <=> 4-androstene-3,17-dione + NADP+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
lanosterol + NADP+ <=> lanosterone + NADPH + CO2 + H+ 1.1.1.417 3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating)
–
2-[4-[(E)-(2-oxocyclohexylidene)methyl]phenyl]propanoic_acid + NADPH <=> 2-[4-[(2-oxocyclohexyl)methyl]phenyl]propanoic_acid + NADP+ 1.3.1.74 2-alkenal reductase [NAD(P)+]
–
salicylate + NADPH + ATP <=> Salicylaldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
ferulic_acid + NADPH + ATP <=> coniferyl_aldehyde + NADP+ + AMP + phosphate 1.2.1.30 carboxylate reductase (NADP+)
–
benzoate + NADPH + ATP <=> benzaldehyde + benzyl_alcohol + NADP+ + AMP + phosphate 1.2.1.30 carboxylate reductase (NADP+)
–
benzoate + NADPH + ATP <=> benzaldehyde + NADP+ + AMP + phosphate 1.2.1.30 carboxylate reductase (NADP+)
–
ferulic_acid + NADPH + ATP <=> ferulic_acid + coniferyl_aldehyde + coniferyl_alcohol + NADP+ + AMP + phosphate 1.2.1.30 carboxylate reductase (NADP+)
–
vanillic_acid + NADPH + ATP <=> Vanillin + Vanillyl_alcohol + NADP+ + AMP + phosphate 1.2.1.30 carboxylate reductase (NADP+)
–
vanillic_acid + NADPH + ATP <=> Vanillin + NADP+ + AMP + phosphate 1.2.1.30 carboxylate reductase (NADP+)
–
ferulic_acid + NADPH + ATP <=> coniferyl_aldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
D-2-Aminoadipic_acid + NADPH + H+ + ATP <=> (R)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate 1.2.1.95 L-2-aminoadipate reductase
–
Decanoate + ATP + NADPH + H+ <=> decanal + AMP + diphosphate + NADP+ 1.2.1.30 carboxylate reductase (NADP+)
–
D-tyrosine + NADPH + H+ + ATP <=> D-tyrosinal + NADP+ + AMP + diphosphate 1.2.1.101 L-tyrosine reductase
–
laurate + ATP + NADPH + H+ <=> dodecanal + AMP + diphosphate + NADP+ 1.2.1.30 carboxylate reductase (NADP+)
–
fatty_acid + ATP + NADPH + H+ <=> octadecanal + AMP + diphosphate + NADP+ 1.2.1.30 carboxylate reductase (NADP+)
–
ATP + Acrylate + CoA + NADPH <=> AMP + diphosphate + NADP+ + propionyl-CoA 6.2.1.17 propionate---CoA ligase
–
Butyrate + ATP + NADPH + H+ <=> Butyraldehyde + AMP + diphosphate + NADP+ 1.2.1.30 carboxylate reductase (NADP+)
–
adipate + NADPH + H+ + ATP <=> 6-oxohexanoate + NADP+ + AMP + diphosphate 1.2.1.95 L-2-aminoadipate reductase
–
hexanoate + ATP + NADPH + H+ <=> hexanal + AMP + diphosphate + NADP+ 1.2.1.30 carboxylate reductase (NADP+)
–
Octanoate + ATP + NADPH + H+ <=> octanal + AMP + diphosphate + NADP+ 1.2.1.30 carboxylate reductase (NADP+)
–
S-carboxymethyl-L-cysteine + NADPH + H+ + ATP <=> S-(2-oxoethyl)-L-cysteine + NADP+ + AMP + diphosphate 1.2.1.95 L-2-aminoadipate reductase
–
aromatic_acids + NADPH + ATP <=> an_aromatic_aldehyde + NADP+ + AMP + diphosphate + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
(R)-ibuprofen + NADPH + ATP <=> (2R)-2-(4-(2-methylpropyl)phenyl)propanal + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
benzoate + NADPH + ATP <=> benzaldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
3-hydroxybenzoate + NADPH + ATP <=> 3-Hydroxybenzaldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
coumaric_acid + NADPH + ATP <=> 2-hydroxycinnamaldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
Ibuprofen + NADPH + ATP <=> 2-(4-isobutylphenyl)propanal + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
Sinapic_acid + NADPH + ATP <=> sinapaldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
caffeic_acid + NADPH + ATP <=> caffeoyl_aldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
p-coumaric_acid + NADPH + ATP <=> 4-coumaraldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
4-hydroxybenzoate + NADPH + ATP <=> 4-hydroxybenzaldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
3-hydroxycinnamic_acid + NADPH + ATP <=> 3-(3-hydroxyphenyl)-2-propen-1-al + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
aromatic_acids + NADPH + ATP <=> an_aromatic_aldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
4-Methoxybenzoate + NADPH + ATP <=> 4-methoxybenzaldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
Cinnamic_acid + NADPH + ATP <=> cinnamaldehyde + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
vanillic_acid + NADPH + ATP <=> Vanillin + NADP+ + AMP + H2O 1.2.1.30 carboxylate reductase (NADP+)
–
L-prolyl-L-threonyl-L-valyl-L-threonyl-N-[(4R,7R)-4-[(2-amino-2-oxoethyl)carbamoyl]-6-oxo-1,2,5-thiaselenazocan-7-yl]glycinamide + NADPH + H+ <=> L-prolyl-L-threonyl-L-valyl-L-threonylglycyl-L-cysteinyl-3-selanyl-L-alanylglycinamide + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
L-prolyl-L-threonyl-L-valyl-L-threonyl-N-[(4R,7R)-4-[(carboxymethyl)carbamoyl]-6-oxo-1,2,5-thiaselenazocan-7-yl]glycinamide + NADPH + H+ <=> L-prolyl-L-threonyl-L-valyl-L-threonylglycyl-L-cysteinyl-3-selanyl-L-alanylglycine + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
L-prolyl-L-threonyl-L-valyl-L-threonyl-N-[(4R,7R)-4-[(2-amino-2-oxoethyl)carbamoyl]-6-oxo-1,2,5-dithiazocan-7-] + NADPH + H+ <=> L-prolyl-L-threonyl-L-valyl-L-threonylglycyl-L-cysteinyl-L-cysteinylglycinamide + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
L-prolyl-L-threonyl-L-valyl-L-threonyl-N-[(4R,7R)-4-[(carboxymethyl)carbamoyl]-6-oxo-1,2,5-dithiazocan-7-yl]glycinamide + NADPH + H+ <=> L-prolyl-L-threonyl-L-valyl-L-threonylglycyl-L-cysteinyl-L-cysteinylglycine + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
1-deoxy-D-xylulose_5-phosphate + NADPH <=> methyl-D-erythritol-4-phosphate + NADP+ 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase
–
1-(4''-carboxyphenylazo)-2-hydroxy-6-sulfonaphthalene + NADPH <=> 4-Aminobenzoic_acid + NADP+ + 1-amino-2-hydroxy-6-sulfonaphthalene 1.7.1.6 azobenzene reductase
–
1-(4''-carboxyphenylazo)-4-naphthol + NADPH <=> 4-Aminobenzoic_acid + NADP+ + 4-amino-1-naphthol 1.7.1.6 azobenzene reductase
–
1-(4''-carboxyphenylazo)-2-naphthol + NADPH <=> 4-Aminobenzoic_acid + NADP+ + 1-amino-2-hydroxynaphthalene 1.7.1.6 azobenzene reductase
–
chanoclavine-I_aldehyde + NADPH + H+ <=> festuclavine + pyroclavine + NADP+ 1.5.1.46 agroclavine dehydrogenase
–
(8beta,10beta)-6-amino-8-methyl-6,7-didehydroergolin-6-ium + NADPH + H+ <=> festuclavine + NADP+ 1.5.1.46 agroclavine dehydrogenase
–
beta-D-glucose + NADP+ + H2O <=> D-gluconate + NADPH + 2 H+ 1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
–
3alpha,5alpha-allopregnenolone + NADP+ <=> 5alpha-dihydroprogesterone + NADPH 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
1-phenyl-2-propanol + NADP+ <=> phenylacetone + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
2-cis,4-cis/trans-dienoyl-CoA + NADPH + H+ <=> 3-trans-enoyl-CoA + NADP+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
[7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine + NADPH + H+ + O2 <=> [7-(2,6-dichlorophenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-(4-[2-(1-oxy-pyrrolidin-1-yl)-ethoxy]-phenyl)-amine + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
(1S,4R)-iso-dihydrocarvone + NADPH + H+ + O2 <=> (3S,4R)-6-isopropenyl-3-methyl-2-oxo-oxepanone + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
2'-fluoroacetophenone + NADPH + H+ <=> (1S)-1-(2-fluorophenyl)ethanol + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
1-(2-thienyl)acetone + NADPH + H+ <=> 1-thien-2-ylethanol + NADP+ 1.1.1.B4
–
2-Methylcyclopentanone + NADPH + H+ + O2 <=> 1-oxa-2-oxo-3-methyl-cyclohexane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
3'-fluoroacetophenone + NADPH + H+ <=> (1S)-1-(3-fluorophenyl)ethanol + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
3-oxo-3-(2,4-difluorophenyl)propanenitrile + NADPH <=> (R)-3-hydroxy-3-(2,4-difluorophenyl)propanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-oxo-3-(3-methoxyphenyl)propanenitrile + NADPH <=> (R)-3-hydroxy-3-(3-methoxyphenyl)propanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-oxo-3-(3-nitrophenyl)propanenitrile + NADPH <=> (R)-3-hydroxy-3-(3-nitrophenyl)propanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-oxo-3-(4-bromophenyl)propanenitrile + NADPH <=> (R)-3-hydroxy-3-(4-bromophenyl)propanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-oxo-3-(4-chlorophenyl)propanenitrile + NADPH <=> (R)-3-hydroxy-3-(4-chlorophenyl)propanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-oxo-3-(4-cyanophenyl)propanenitrile + NADPH <=> (R)-3-hydroxy-3-(4-cyanophenyl)propanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-oxo-3-(4-fluorophenyl)propanenitrile + NADPH <=> (R)-3-hydroxy-3-(4-fluorophenyl)propanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-oxo-3-(4-methylphenyl)propanenitrile + NADPH <=> (R)-3-hydroxy-3-(4-methylphenyl)propanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-oxo-3-(4-nitrophenyl)propanenitrile + NADPH <=> (R)-3-hydroxy-3-(4-nitrophenyl)propanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
3-oxo-3-phenylpropanenitrile + NADPH <=> (R)-3-hydroxy-3-phenylpropanenitrile + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
4-chloroacetophenone + NADPH + H+ <=> (S)-1-(4-chlorophenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
4-methoxyacetophenone + NADPH <=> (1S)-1-(4-methoxyphenyl)ethanol + (1R)-1-(4-methoxyphenyl)ethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
benzylacetone + NADPH + H+ <=> (2R)-4-phenylbutan-2-ol + NADP+ 1.1.1.B4
–
5beta-pregnan-20alpha-ol-3-one + NADPH + H+ <=> 5beta-pregnan-3beta,20alpha-diol + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
hexadecanal + protein + NADP+ <=> a_[protein]-S-(long-chain_fatty_acyl)-L-cysteine + NADPH + H+ 1.2.1.50 long-chain acyl-protein thioester reductase
–
Biliverdin + NADPH + H+ <=> bilirubin_IXalpha + NADP+ 1.3.1.24 biliverdin reductase
–
cholestanol + NADPH + H+ + O2 <=> 22-hydroxy-cholestanol + NADP+ + H2O 1.14.99.B1
–
clozapine + NADPH + H+ + O2 <=> clozapine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
dodecenoyl-N-acetyl-cysteamine + NADPH + H+ <=> dodecanoyl-N-acetyl-cysteamine + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
–
ergosta-5,7-dienol + NADPH <=> ergosta-5-enol + NADP+ 1.3.1.21 7-dehydrocholesterol reductase
–
Ethionamide + NADPH + H+ + O2 <=> ethionamide_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
ethyl_4,4,4-trifluoro-3-oxobutanoate + NADPH + H+ <=> 1-ethoxy-2,2,2-trifluoroethanol + NADP+ 1.1.1.1 alcohol dehydrogenase
–
indole + NADPH + H+ + O2 <=> indole_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
itopride + NADPH + H+ + O2 <=> itopride_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
K11777 + NADPH + H+ + O2 <=> K11777_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
Methamphetamine + NADPH + H+ + O2 <=> methamphetamine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
Methimazole + NADPH + H+ + O2 <=> methimazole_N-oxide + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
N,N-dimethyl-3-keto-2-thienyl-propanamine + NADPH <=> (S)-N,N-dimethyl-3-keto-2-thienyl-propanamine + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
N-deacetyl_ketoconazole + NADPH + H+ + O2 <=> N-deacetyl_ketoconazole_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
N-deacetyloxoconazole + NADPH + H+ + O2 <=> N-deacetyl_ketoconazole_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
olopatadine + NADPH + H+ + O2 <=> olopatadine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
orphenadrine + NADPH + H+ + O2 <=> orphenadrine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
peroxynitrite + 4-hydroxyphenylacetate + NADPH + H+ <=> 4-hydroxyl-3-nitro-phenylacetic_acid + NADP+ + H2O 1.14.13.39 nitric-oxide synthase (NADPH)
–
progesterone + NADPH <=> 5beta-pregnan-3,11,20-trione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
pyrazolacridine + NADPH + H+ + O2 <=> pyrazolacridine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
4-(4-methylphenyl)-2-methylsulfanylmethyl-4-oxobutyric_acid + NADPH + H+ + O2 <=> S-methyl_esonarimod_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
S16020 + NADPH + H+ + O2 <=> S16020_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
sitosterol + NADPH + H+ + O2 <=> 22-hydroxy-sitosterol + NADP+ + H2O 1.14.99.B1
–
tazarotenic_acid + NADPH + H+ + O2 <=> tazarotenate_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
thiacetazone + NADPH + H+ + O2 <=> thiacetazone_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
xanomeline + NADPH + H+ + O2 <=> xanomeline_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2,5-dimethoxy-1,3-benzothiazole-4,7-dione + NADPH <=> 2,5-dimethoxy-1,3-benzothiazole-4,7-diol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
2,5-dimethoxy-1-methyl-1H-benzimidazole-4,7-dione + NADPH <=> 2,5-dimethoxy-1-methyl-1H-benzimidazole-4,7-diol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
methylamine + oxaloacetate + NADPH <=> L-aspartate + H2O + NADP+ 1.4.1.17 N-methylalanine dehydrogenase
–
3-(hydroxymethyl)-5-methoxy-1-methyl-2-phenyl-1H-indole-4,7-dione + NADPH <=> 3-(hydroxymethyl)-5-methoxy-1-methyl-2-phenyl-1H-indole-4,7-diol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
hexane + NADPH + O2 <=> 1-Hexanol + 2-Hexanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
diethyl_[2,5-bis(aziridin-1-yl)-3,6-dioxocyclohexa-1,4-diene-1,4-diyl]biscarbamate + NADPH <=> diethyl_[2,5-bis(aziridin-1-yl)-3,6-dihydroxybenzene-1,4-diyl]biscarbamate + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
alpha-tocopherolquinone + NADPH <=> reduced_alpha-tocopherolquinone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
beta-lapachone + NADPH <=> reduced_beta-lapachone + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
mitomycin_C + NADPH <=> reduced_mitomycin_C + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
Streptonigrin + NADPH <=> reduced_streptonigrin + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
androst-4-ene-3,11,17-trione + NADPH <=> 11-oxo-testosterone + NADP+ 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
L-cysteine + NADPH <=> L-cystine + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
ethyl_pyruvate + NADPH + H+ <=> Lactate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
D-arabitol_1-phosphate + NADP+ <=> D-xylulose_5-phosphate + NADPH + H+ 1.1.1.301 D-arabitol-phosphate dehydrogenase
–
piperitone + NADP+ <=> d-isomenthone + NADPH + H+ 1.3.1.82 (-)-isopiperitenone reductase
–
(S)-2-hexanol + NADP+ <=> 2-Hexanone + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
1-(4''-nitrophenylazo)-2-hydroxy-6-sulfonaphthalene + NADPH <=> 4-nitroaniline + NADP+ + 1-amino-2-hydroxy-6-sulfonaphthalene 1.7.1.6 azobenzene reductase
–
n-Octylboronic_acid + NADPH + O2 <=> 1-Octanol + BO33- + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
Octane + NADPH + O2 <=> 1-Octanol + 2-Octanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
1-Octanol + 2 NADP+ + H2O <=> Octanoate + 2 NADPH + 2 H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.192 long-chain-alcohol dehydrogenase
–
–
geranylgeranyl-chlorophyll + 3 NADPH + 3 H+ <=> phytyl-chlorophyll + 3 NADP+ 1.3.1.83 geranylgeranyl diphosphate reductase
–
(+)-alpha-pinene + NADPH + H+ + O2 <=> verbenol + NADP+ + H2O 1.14.14.31 ipsdienol synthase
–
DELTA7-avenasterol + NADPH + H+ <=> stigmast-7-en-3beta-ol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
geranylgeranyl-bacteriopheophytin_a + NADPH + H+ <=> phytyl-bacteriopheophytin_a + NADP+ 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase
–
2-chloroethyl_phenyl_sulfide + NADPH + H+ + O2 <=> 2-chloroethyl_phenyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
2-chloro-thioanisole + NADPH + H+ + O2 <=> 2-chlorophenyl_methyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
3-chloro-thioanisole + NADPH + H+ + O2 <=> 3-chlorophenyl_methyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
1-chloro-4-(methylsulfanyl)benzene + NADPH + H+ + O2 <=> 4-chlorophenyl_methyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
1-methoxy-4-(methylsulfanyl)benzene + NADPH + H+ + O2 <=> 4-methoxyphenyl_methyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-(methylsulfanyl)aniline + NADPH + H+ + O2 <=> 4-[(S)-methylsulfinyl]aniline + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-cyano-thioanisole + NADPH + H+ + O2 <=> 4-[(S)-methylsulfinyl]benzonitrile + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
benzyl_1-methylethyl_sulfide + NADPH + H+ + O2 <=> benzyl_1-methylethyl_(R)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
benzyl_butyl_sulfide + NADPH + H+ + O2 <=> benzyl_butyl_(R)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
benzyl_methyl_sulfide + NADPH + H+ + O2 <=> benzyl_methyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
benzyl_propyl_sulfide + NADPH + H+ + O2 <=> benzyl_propyl_(R)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
butyl_phenyl_sulfide + NADPH + H+ + O2 <=> butyl_phenyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
chloromethyl_phenyl_sulfide + NADPH + H+ + O2 <=> chloromethyl_phenyl_(R)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
phenyl_cyclopropyl_thioether + NADPH + H+ + O2 <=> cyclopropyl_phenyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
ethenyl_phenyl_sulfide + NADPH + H+ + O2 <=> ethenyl_phenyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
ethyl_phenyl_sulfide + NADPH + H+ + O2 <=> ethyl_phenyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
methoxymethyl_phenyl_sulfide + NADPH + H+ + O2 <=> methoxymethyl_phenyl_(R)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
methyl_2-phenylethyl_sulfide + NADPH + H+ + O2 <=> methyl_2-phenylethyl_(R)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
methyl_3-phenylpropyl_sulfide + NADPH + H+ + O2 <=> methyl_3-phenylpropyl_(R)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
1-nitro-4-(methylsulfanyl)benzene + NADPH + H+ + O2 <=> methyl_4-nitrophenyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
methyl_naphthalen-2-yl_sulfide + NADPH + H+ + O2 <=> methyl_naphthalen-2-yl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
Phenyl_allyl_sulfide + NADPH + H+ + O2 <=> phenyl_prop-2-en-1-yl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
phenyl_propyl_sulfide + NADPH + H+ + O2 <=> phenyl_propyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
divinyl_protochlorophyllide_a + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + NADPH + H+ <=> protochlorophyllide + oxidized_ferredoxin + NADP+ 1.3.7.13 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin)
–
5-[[3-(dimethylamino)propyl]amino]-8-methoxy-6H-[1,2,3]triazolo[4,5,1-de]acridin-6-one + NADPH + H+ + O2 <=> 5-[[3-(dimethylnitroryl)propyl]amino]-8-methoxy-6H-[1,2,3]triazolo[4,5,1-de]acridin-6-one + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
magnesium_protoporphyrin_monomethyl_ester + NADPH + O2 <=> protochlorophyllide + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
Mg-protoporphyrin_IX_monomethyl_ester + O2 + NADPH + H+ <=> protochlorophyllide + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
8-vinyl_protochlorophyllide_a + NADPH + H+ <=> protochlorophyllide + NADP+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
5alpha-cholest-22-en-3beta-ol + O2 + NADPH + H+ <=> 5alpha-cholest-7,22-dien-3beta-ol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
3-oxo-3-phenylpropanenitrile + NADPH + H+ <=> (3S)-3-hydroxy-3-phenylpropanenitrile + NADP+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
3alpha,17beta-androstene-3,17-diol + NADP+ <=> 5alpha-dihydrotestosterone + NADPH + H+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
Trichloroethylene + O2 + NADPH <=> formate + glyoxylate + NADP+ 1.14.12.11 toluene dioxygenase
–
cis-4-cyclopentene-1,3-diol + NADP+ <=> (R)-4-hydroxy-2-cyclopentenone + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
L-1-amino-2-butanol + NADP+ <=> 1-amino-2-oxobutane + NADPH + H+ 1.1.1.75 (R)-aminopropanol dehydrogenase
–
5,22-cholestedien-3beta-ol + O2 + NADPH + H+ <=> cholest-5,7,22-trien-3beta-ol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
cholestanol + O2 + NADPH + H+ <=> cholest-5,7,22-trien-3beta-ol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
[4Fe-4S]-ferredoxin + NADPH <=> reduced_[4Fe-4S]-ferredoxin + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
–
2 decyl-plastoquinone + NADPH + H+ <=> 2 decyl-plastosemiquinone + NADP+ 1.6.5.5 NADPH:quinone reductase
–
2-n-propylcyclohexanone + NADPH + O2 + H+ <=> (7S)-7-propyloxepan-2-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
3-phenyl-2-pentanone + NADPH + H+ + O2 <=> 1-phenylpropyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-hydroxy-2-decanone + NADPH + H+ + O2 <=> 4-hydroxyoctyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-hydroxy-2-octanone + NADPH + H+ + O2 <=> 4-hydroxyhexyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-hydroxy-2-undecanone + NADPH + H+ + O2 <=> 4-hydroxynonyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-hydroxy-4-phenyl-2-butanone + NADPH + H+ + O2 <=> 1-hydroxy-1-phenylethyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
5-bromo-1-indanone + NADPH + H+ + O2 <=> 5-bromo-3,4-dihydrochromen-2-one + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
5-chloro-1-indanone + NADPH + H+ + O2 <=> 5-chloro-3,4-dihydrochromen-2-one + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
Plumbagin + NADPH + H+ <=> 5-hydroxy-2-methyl-1,4-naphthosemiquinone + NADP+ 1.6.5.5 NADPH:quinone reductase
–
5-methoxy-1-indanone + NADPH + H+ + O2 <=> 5-methoxy-3,4-dihydrochromen-2-one + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
6-chloro-1-indanone + NADPH + H+ + O2 <=> 7-chloro-3,4-dihydrochromen-2-one + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
6-methoxy-1-indanone + NADPH + H+ + O2 <=> 6-methoxy-3,4-dihydrochromen-2-one + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
D-fucose + NADP+ <=> D-fucono-gamma-lactone + NADPH + H+ 1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
–
octahydronaphthalen-2(1H)-one + NADPH + H+ + O2 <=> cis-octahydro-benzo[c]oxepin-3-one + trans-octahydro-benzo[c]oxepin-3-one + cis-octahydro-7-oxa-benzocyclohepten-6-one + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
thioanisole + NADPH + H+ + O2 <=> methyl_phenyl_(S)-sulfoxide + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
(S)-pulegone + NADP+ <=> (1S,4S)-isomenthone + (1S,4R)-menthone + NADPH + H+ 1.1.1.54 allyl-alcohol dehydrogenase
–
NADPH + 5-cyano-2,3-ditolyl_tetrazolium_chloride <=> NADP+ + (5-cyano-2,3-di-p-tolyltetrazolium_chloride)_formazan 1.6.2.4 NADPH---hemoprotein reductase
–
taurocholate + NADP+ <=> 2[[7alpha,12alpha-Dihydroxy-3,24-dioxo-5beta-cholan-24-yl]amino]ethane_sulfonic_acid + NADPH 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
taurocholate + NADP+ <=> 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl_taurine + NADPH 1.1.1.176 12alpha-hydroxysteroid dehydrogenase
–
(9E)-9-nitrooctadec-9-enoic_acid + NADP+ <=> 9-nitrostearic_acid + NADP+ 1.3.1.16 beta-nitroacrylate reductase
–
(R)-acetoin + NADPH + H+ <=> (2R,3R)-butane-2,3-diol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.4 (R,R)-butanediol dehydrogenase
–
–
acetoin + NADPH + H+ <=> (2R,3R)-butane-2,3-diol + NADP+ 1.1.1.4 (R,R)-butanediol dehydrogenase
–
diacetyl + NADH <=> acetoin + NADP+ 1.1.1.162 erythrulose reductase
–
acetoin + NADP+ <=> 2,3-Butanediol + NADPH + H+ 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
chenodeoxycholic_acid + NADP+ <=> (5beta,7alpha,8xi)-7-hydroxy-3-oxocholan-24-oic_acid + NADPH + H+ 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
3,7-dimethyl-1-octanol + NADP+ <=> 3,7-dimethyloctanal + NADPH + H+ 1.1.1.183 geraniol dehydrogenase (NADP+)
–
L-lysine + NADPH + H+ + O2 <=> L-lysine_N6-oxide + NADP+ + H2O 1.14.13.195 L-ornithine N5-monooxygenase (NADPH)
–
N,N-dimethylamphetamine + NADPH + H+ + O2 <=> N,N-dimethylamphetamine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
S-(4-hydroxy-1-oxononan-3-yl)glutathione + NADP+ <=> 3-glutathionyl_nonanoic-delta-lactone + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
–
(-)-limonene + NADPH + O2 <=> (S)-trans-1,2_limonene_epoxide + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
5alpha-androstane-3alpha,17beta-diol + NADPH + O2 <=> 5alpha-androstane-3alpha,7alpha,17beta-triol + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
7-hydroxy-flavanone + NADPH + H+ <=> 2,4-cis-7-hydroxyflavan-4-ol + 2,4-trans-7-hydroxyflavan-4-ol + NADP+ 1.1.1.219 dihydroflavonol 4-reductase
–
atropine + NADPH + O2 <=> atropine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
chlorpromazine + NADPH + H+ + O2 <=> chlorpromazine_oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
naringenin + NADPH + H+ <=> apiferol + NADP+ 1.1.1.219 dihydroflavonol 4-reductase
–
nerylacetone + NADPH + O2 <=> 9,10-epoxynerylacetone + 5,6-epoxynerylacetone + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
phalaenopsine + NADPH + O2 <=> phalaenopsine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
thiobenzamide + NADPH + H+ + O2 <=> thiobenzamide_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
thiacetazone + NADPH + H+ + O2 <=> thiacetazone_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
L-alanine + H2O + NADP+ <=> pyruvate + NH3 + NADPH 1.4.1.1 alanine dehydrogenase
1.4.1.2 glutamate dehydrogenase
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
–
–
–
quinonoid_7,8-dihydro-6-methylpterin + NADPH <=> 6-Methyl-5,6,7,8-tetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
2-amino-4-hydroxy-6-methyl-7,8-dihydropteridine + NADPH <=> 6-Methyl-5,6,7,8-tetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
2-amino-4-hydroxy-7-methyl-dihydropteridine + NADPH <=> 6-Methyl-5,6,7,8-tetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
D-galacturonate + NADPH + H+ <=> L-galactono-1,4-lactone + NADP+ 1.1.1.203 uronate dehydrogenase
–
L-phenylalanine + H2O + NADP+ <=> phenylpyruvate + NH3 + NADPH 1.4.1.16 diaminopimelate dehydrogenase
1.4.1.2 glutamate dehydrogenase
1.4.1.20 phenylalanine dehydrogenase
–
–
–
NADPH + 3-pyridinealdehyde-NAD+ <=> NADP+ + pyridine_aldehyde-NADH 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
–
9-fluorenone + NADPH + H+ + O2 <=> 1,1a-dihydroxy-1-hydrofluoren-9-one + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
RJC_03297 + NADPH + H+ + O2 <=> 2,2'',3-trihydroxydiphenyl_sulfide + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
xanthene + NADPH + H+ + O2 <=> 2,2'',3-trihydroxydiphenylmethane + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
D-glucose_6-phosphate + NADP+ <=> 2-dehydro-6-phospho-D-glucose + NADPH 1.1.1.43 phosphogluconate 2-dehydrogenase
–
D-glucose_6-phosphate + H2O + NADP+ <=> 6-phosphogluconate + NADPH + H+ 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
D-glucose_6-phosphate + NADP+ <=> 7-phospho-D-glucono-1,5-lactone + NADPH + H+ 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
ADP + NAD+ <=> AMP + NADP+ 2.7.1.23 NAD+ kinase
–
NADP+ + H2O <=> NMN + adenosine_2'',5''-phosphate 3.6.1.9 nucleotide diphosphatase
–
NADP+ + H2O <=> NMN + adenosine_3'',5''-diphosphate 3.6.1.22 NAD+ diphosphatase
–
NADP+ + H2O <=> nicotinic_mononucleotide + phosphate 3.6.1.13 ADP-ribose diphosphatase
3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
–
–
2'',3''-cyclic_NADP+ + H2O <=> NADP+ 3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase
–
NADP+ + H2O <=> phospho-ADPribose + nicotinamide 3.2.2.5 NAD+ glycohydrolase
–
NADP+ + H2O <=> nicotinamide + ADPribose-phosphate 3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
–
2'',3''-cNADP+ + H2O <=> NADP+ 3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase
–
H2 + NADPH <=> NADP+ + H+ 1.12.99.6 hydrogenase (acceptor)
–
1,2-dehydro-N-methylcoclaurine_NADPH + H+ <=> N-Methylcoclaurine + NADP+ 1.5.1.27 1,2-dehydroreticulinium reductase (NADPH)
–
17alpha,21-dihydroxy-5beta-pregnane-3,11,20-trione_NADPH + H+ <=> 17alpha,20alpha,21-trihydroxy-5beta-pregnane-3,11-dione + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
methylmalonyl-S-N-acetylcysteamine + S-phenyl_(2S,4R,6E,8R,9R)-9-hydroxy-2,4,8-trimethyl-5-oxoundec-6-enethioate <=> 3-dehydro-10-deoxymethynolide + 10-deoxymethynolide + CoA + CO2 + NADP+ + H2O 2.3.1.239 10-deoxymethynolide synthase
–
methylmalonyl-S-N-acetylcysteamine + S-phenyl_(2S,4R,6E,8R,9R)-9-hydroxy-2,4,8-trimethyl-5-oxoundec-6-enethioate <=> 3-dihydro-narbonolide + 10-deoxymethynolide + CoA + CO2 + NADP+ + H2O 2.3.1.240 narbonolide synthase
–
D-glucose + NADP+ <=> H+ + D-glucono-1,4-lactone + NADPH 1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
–
O2 + NADPH + leukotriene_B4 + H+ <=> H2O + NADP+ + 20-hydroxy-leukotriene_B4 1.14.14.94 leukotriene-B4 20-monooxygenase
–
trans-cinnamate + H+ + O2 + NADPH <=> H2O + NADP+ + p-coumaric_acid 1.14.14.91 trans-cinnamate 4-monooxygenase
–
NADPH + H+ + formononetin + O2 <=> H2O + 2''-Hydroxyformononetin + NADP+ 1.14.14.90 isoflavone 2'-hydroxylase
–
O2 + formononetin + H+ + NADPH <=> NADP+ + H2O + Calycosin 1.14.14.88 isoflavone 3'-hydroxylase
–
2 NADP+ + cyanidin <=> H+ + 2 NADPH + (-)-epicatechin 1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
delphinidin + 2 NADP+ <=> epigallocatechin + 2 NADPH + H+ 1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
pelargonidin + 2 NADP+ <=> H+ + (-)-epiafzelechin + 2 NADPH 1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
O2 + NADPH + H+ + Biochanin_A <=> H2O + 2''-Hydroxybiochanin_A + NADP+ 1.14.14.90 isoflavone 2'-hydroxylase
–
purine + NADP+ <=> NADPH + H+ + xanthine not assigned
 –
O2 + NADPH + coumarin + H+ <=> NADP+ + umbelliferone + H2O 1.14.14.1 unspecific monooxygenase
–
H+ + O2 + 4-Methylumbelliferone + NADPH <=> NADP+ + formaldehyde + umbelliferone + H2O 1.14.14.1 unspecific monooxygenase
–
NADP+ + 2-Hydroxypurine <=> NADPH + H+ + xanthine not assigned
 –
4-Methylumbelliferone + O2 + H+ + NADPH <=> NADP+ + H2O + 3-Hydroxy-7-methoxycoumarin 1.14.14.1 unspecific monooxygenase
–
4-Methylumbelliferone + O2 + NADPH + H+ <=> 3-Hydroxy-7-ethoxycoumarin + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
NADPH + H+ + O2 + 4-Methylumbelliferone <=> NADP+ + umbelliferone + H2O + acetaldehyde 1.14.14.1 unspecific monooxygenase
–
NADPH + S-1360 <=> HP1 + NADP+ not assigned
 –
an_alcohol + NADP+ <=> NADPH + (+)-Camphorquinone + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
2-Oxopentanoate + NADPH + H+ <=> 2-Hydroxyisovalerate + NADP+ 1.1.1.169 2-dehydropantoate 2-reductase
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
D-glucuronate + H+ + NADPH <=> L-gulonate + NADP+ 1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.365 D-galacturonate reductase
–
–
–
–
O2 + NADPH + H+ + cholesterol <=> H2O + 7alpha-hydroxycholesterol + NADP+ 1.14.14.23 cholesterol 7alpha-monooxygenase
–
NADP+ + D-arabinose <=> H+ + D-arabinono-1,4-lactone + NADPH 1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
nevirapine + NADPH + O2 + H+ <=> H2O + 2-Hydroxy-nevirapine + NADP+ 1.14.14.55 quinine 3-monooxygenase
–
H+ + 2-Chloro-1,3-butadiene + O2 + NADPH <=> (1-Chloroethenyl)oxirane + NADP+ + H2O not assigned
 –
H+ + NADPH + O2 + 7-Benzyloxyquinoline <=> NADP+ + 7-Hydroxyquinoline + H2O + benzaldehyde 1.14.14.1 unspecific monooxygenase
1.14.14.55 quinine 3-monooxygenase
–
–
2 NADPH + 2 H+ + 2 O2 + 5-epiaristolochene <=> 2 H2O + 2 NADP+ + capsidiol 1.14.14.149 5-epiaristolochene 1,3-dihydroxylase
–
NADPH + L-Lyxose <=> NADP+ + L-arabitol 1.1.1.21 aldose reductase
–
NADP+ + (R)-indanol <=> NADPH + 1-Indanone 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
–
H2O + NADP+ + malondialdehyde <=> H+ + malonate_semialdehyde + NADPH 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
NADPH + 3,4'',5-Trihydroxystilbene + O2 + H+ <=> NADP+ + H2O + oxyresveratrol 1.14.14.57 taurochenodeoxycholate 6alpha-hydroxylase
–
N-ethylmaleimide + H+ + NADPH <=> N-ethylmaleimide + NADP+ 1.6.99.1 NADPH dehydrogenase
–
NADPH + nitroglycerin + H+ <=> NADP+ + nitroglycerin 1.6.99.1 NADPH dehydrogenase
–
L-threonine + NADP+ <=> H+ + L-2-amino-3-oxobutanoate + NADPH 1.1.1.103 L-threonine 3-dehydrogenase
–
testosterone + O2 + H+ + NADPH <=> NADP+ + H2O + 15beta-hydroxytestosterone 1.14.14.55 quinine 3-monooxygenase
–
NADPH + testosterone + O2 + H+ <=> NADP+ + H2O + 2beta-hydroxytestosterone 1.14.14.55 quinine 3-monooxygenase
–
testosterone + O2 + H+ + NADPH <=> H2O + 1beta-Hydroxytestosterone + NADP+ 1.14.14.55 quinine 3-monooxygenase
–
L-idose + NADPH + H+ <=> L-Iditol + NADP+ 1.1.1.21 aldose reductase
–
H+ + 2-deoxy-D-ribose + NADPH <=> 2-deoxy-D-ribitol + NADP+ 1.1.1.21 aldose reductase
–
D-Lyxose + H+ + NADPH <=> D-arabitol + NADP+ 1.1.1.21 aldose reductase
–
NADPH + D-fucose + H+ <=> NADP+ + D-Fucitol 1.1.1.21 aldose reductase
–
NADPH + 17alpha-hydroxyprogesterone <=> 4-androstene-3,17-dione + NADP+ 1.14.14.19 steroid 17alpha-monooxygenase
–
NADPH + 17alpha-hydroxypregnenolone <=> dehydroepiandrosterone + NADP+ 1.14.14.19 steroid 17alpha-monooxygenase
–
progesterone + NADPH + O2 <=> 17alpha-hydroxyprogesterone + NADP+ + H2O 1.14.14.19 steroid 17alpha-monooxygenase
1.14.14.25 cholesterol 24-hydroxylase
–
–
NADPH + O2 + pregnenolone <=> 17alpha-hydroxypregnenolone + NADP+ + H2O 1.14.14.19 steroid 17alpha-monooxygenase
–
H+ + O2 + NADPH + testosterone <=> H2O + NADP+ + formate + 17beta-estradiol 1.14.14.1 unspecific monooxygenase
–
H+ + 4-androstene-3,17-dione + NADPH + O2 <=> NADP+ + formate + estrone + H2O 1.14.14.1 unspecific monooxygenase
–
H+ + 7-ethoxy-4-trifluoromethylcoumarin + O2 + NADPH <=> NADP+ + ethanol + 7-hydroxy-4-trifluoromethylcoumarin 1.14.14.1 unspecific monooxygenase
–
7-ethoxyresorufin + O2 + NADPH + H+ <=> NADP+ + ethanol + resorufin 1.14.14.1 unspecific monooxygenase
–
2-Oxopentanoate + H+ + NADPH <=> 2-Hydroxyisovalerate + NADP+ not assigned
 –
NADPH + 2-Oxopentanoate + H+ <=> D-2-hydroxyvalerate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
H+ + O2 + NADPH + abscisic_acid <=> 8''-Hydroxyabscisate + NADP+ + H2O 1.14.14.137 (+)-abscisic acid 8'-hydroxylase
–
H+ + O2 + leukotriene_B4 + NADPH <=> 19-OH-Leukotriene_B4 + H2O + NADP+ 1.14.14.94 leukotriene-B4 20-monooxygenase
–
H+ + NADPH + ethyl_3-methyl-2-oxobutyrate <=> ethyl-2-hydroxy-3-methylbutyrate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
H+ + D-xylulose + NADPH <=> xylitol + NADP+ 1.1.1.10 L-xylulose reductase
–
2,3-Hexanedione + NADPH <=> 3-Hydroxyhexan-2-one + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
NADPH + H+ + L-threose <=> D-threitol + NADP+ 1.1.1.10 L-xylulose reductase
–
NADPH + 2,3-heptanedione + H+ <=> 3-Hydroxyheptan-2-one + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
methyl_2-chloro-3-oxobutanoate + NADPH + H+ <=> NADP+ + Methyl_2-chloro-3-hydroxybutanoate 1.1.1.184 carbonyl reductase (NADPH)
–
H+ + O2 + benzylacetone + NADPH <=> H2O + phenylacetate + NADP+ 1.14.13.92 phenylacetone monooxygenase
–
3,4-hexanedione + NADPH <=> NADP+ + 4-hydroxy-3-hexanone 1.1.1.10 L-xylulose reductase
1.1.1.184 carbonyl reductase (NADPH)
–
–
2,3-Pentanedione + H+ + NADPH <=> 3-hydroxy-2-pentanone + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
NADPH + H+ + L-erythrulose <=> NADP+ + erythritol 1.1.1.10 L-xylulose reductase
–
NADP+ + Chloral_hydrate <=> NADPH + trichloroacetate + H+ 1.1.1.184 carbonyl reductase (NADPH)
–
oxalosuccinate + NADP+ <=> CO2 + 2-oxoglutarate + H+ + NADPH 1.1.1.42 isocitrate dehydrogenase (NADP+)
–
O2 + H+ + p-hydroxyphenylacetaldoxime + NADPH <=> 4-hydroxymandelonitrile + 2 H2O + NADP+ 1.14.14.37 4-hydroxyphenylacetaldehyde oxime monooxygenase
–
5beta-cholestane-3alpha,7alpha,12alpha-triol + O2 + H+ + NADPH <=> NADP+ + H2O + 5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol 1.14.15.15 cholestanetriol 26-monooxygenase
–
H+ + NADPH + O2 + 5beta-cholestane-3alpha,7alpha-diol <=> 5beta-cholestane-3alpha,7alpha,26-triol + H2O + NADP+ 1.14.15.15 cholestanetriol 26-monooxygenase
–
(S)-tetrahydrocolumbamine + NADPH + O2 <=> (S)-canadine + 2 H2O + NADP+ 1.14.19.68 (S)-canadine synthase
–
5-O-p-coumaroylquinic_acid + O2 + NADPH + H+ <=> H2O + NADP+ + chlorogenic_acid not assigned
 –
NADP+ + Pyridine-4-aldehyde + H2O <=> H+ + NADPH + Isonicotinic_acid 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
H+ + NADPH + 4-methylphenylglyoxal <=> NADP+ + 4-Methylbenzoyl_methanol 1.1.1.21 aldose reductase
–
2 NADPH + 2 H+ + 2,5-dimethyl-4-benzoquinone <=> 2 NADP+ + 2,5-dichlorohydroquinone 1.8.1.9 thioredoxin-disulfide reductase
–
2 NADPH + 5,8-Dihydroxy-1,4-naphthoquinone + 2 H+ <=> 2 NADP+ + 5,8-Dihydroxy-1,4-naphthoquinone 1.8.1.15 mycothione reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
NADPH + corticosterone + H+ <=> NADP+ + 11beta,20alpha,21-Trihydroxy-4-pregnene-3-one 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
H+ + NADPH + cortisone <=> NADP+ + 11beta,17alpha,20alpha,21-Tetrahydroxy-4-pregnene-3-one 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
2-Hydroxy-1,4-naphthoquinone + 2 NADPH + 2 H+ <=> 2 NADP+ + 2-Hydroxy-1,4-naphthoquinone 1.8.1.9 thioredoxin-disulfide reductase
–
NADP+ + cis-benzene_dihydrodiol <=> NADPH + H+ + 2-hydroxycyclohexa-3,5-diene-1-one 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
9,10-phenanthrenequinone + 2 NADPH + 2 H+ <=> 2 NADP+ + trans-9(S),10(S)-Dihydrodiolphenanthrene 1.8.1.9 thioredoxin-disulfide reductase
–
H+ + NADPH + 2,4,6-Trimethylphenylglyoxal <=> 2,4,6-Trimethylbenzoyl_methanol + NADP+ 1.1.1.21 aldose reductase
–
H+ + NADPH + 1-naphthaldehyde <=> NADP+ + 1-naphthalene_methanol 1.1.1.21 aldose reductase
–
NADPH + 4-Phenylphenylglyoxal + H+ <=> NADP+ + 4-Phenylbenzoyl_methanol 1.1.1.21 aldose reductase
–
NADPH + H+ + malondialdehyde <=> 3-hydroxypropionaldehyde + NADP+ 1.1.1.21 aldose reductase
–
NADPH + H+ + 4-bromophenylglyoxal <=> NADP+ + 4-Bromobenzoyl_methanol 1.1.1.21 aldose reductase
–
D-allose + NADPH + H+ <=> D-sorbitol + NADP+ 1.1.1.21 aldose reductase
–
H+ + p-chlorophenylglyoxal + NADPH <=> 4-Chlorobenzoyl_methanol + NADP+ 1.1.1.21 aldose reductase
–
NADPH + H+ + 4-hydroxy-2-nonenal <=> 4-Hydroxynonenol + NADP+ 1.1.1.21 aldose reductase
–
2-naphthaldehyde + H+ + NADPH <=> 2-naphthalenemethanol + NADP+ 1.1.1.21 aldose reductase
–
NADPH + pivaldehyde + H+ <=> 2,2-Dimethylpropanol + NADP+ 1.1.1.21 aldose reductase
–
isatin + NADPH <=> 2,3-Dihydroxyindole + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
–
–
NADPH + H+ + 15-ketoprostaglandin_F2alpha <=> NADP+ + 13,14-dihydro-15-keto-prostaglandin_F2alpha 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
H+ + NADPH + prostaglandin_D1 <=> 9alpha,11alpha-prostaglandin_F2alpha + NADP+ 1.1.1.188 prostaglandin-F synthase
–
Prostaglandin_D3 + H+ + NADPH <=> Prostaglandin_F3alpha + NADP+ 1.1.1.188 prostaglandin-F synthase
–
5beta-androstane-3alpha,17beta-diol + H+ + NADPH <=> NADP+ + androstanediol 1.1.1.188 prostaglandin-F synthase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
O2 + NADPH + H+ + 5alpha-cholestanol <=> H2O + 5beta-Cholestane-3alpha,26-diol + NADP+ 1.14.15.15 cholestanetriol 26-monooxygenase
–
Pradefovir + O2 + NADPH <=> H2O + NADP+ + 9-(2-phosphonylmethoxyethyl)adenine 1.14.14.55 quinine 3-monooxygenase
–
Phenylglyoxal + NADPH + H+ <=> 2-hydroxyacetophenone + NADP+ 1.1.1.188 prostaglandin-F synthase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
1,2-Cyclohexanedione + NADPH + H+ <=> 2-Hydroxycyclohexan-1-one + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
S-sulfocysteine + NADPH + H+ <=> NADP+ + sulfate + L-cysteine not assigned
 –
NADP+ + H2O + Glyoxal <=> H+ + glyoxylate + NADPH 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
NADP+ + Phenylglyoxal + H2O <=> NADPH + benzoylformate + H+ 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
NADP+ + H2O + hydroxypyruvaldehyde <=> Hydroxypyruvate + H+ + NADPH 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
ethylmorphine + NADP+ <=> NADPH + Ethylmorphinone + H+ 1.1.1.218 morphine 6-dehydrogenase
–
NADPH + 2-hydroxyethyl_disulfide + H+ <=> 2 2-mercaptoethanol + NADP+ 1.8.4.2 protein-disulfide reductase (glutathione)
–
H+ + NADPH + 2-oxoglutarate <=> (R)-2-hydroxyglutarate + NADP+ 1.1.1.42 isocitrate dehydrogenase (NADP+)
–
4-Nitroso-N-phenylaniline + H+ + NADPH <=> NADP+ + N-phenyl-p-phenylenediamine 1.1.1.2 alcohol dehydrogenase (NADP+)
–
NADPH + S-nitrosoglutathione <=> Glutathione_sulfinamide + NADP+ 1.1.1.1 alcohol dehydrogenase
–
N,N-Diethyl-4-nitrosoaniline + H+ + NADPH <=> N,N-diethyl-p-phenylenediamine + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
H+ + NADPH + N,N-dimethyl-4-nitrosoaniline <=> N,N-dimethyl-1,4-phenylenediamine + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
NADPH + N,N-dimethyl-4-nitrosoaniline + H+ <=> NADP+ + N,N-dimethyl-1,4-phenylenediamine 1.1.1.2 alcohol dehydrogenase (NADP+)
–
O2 + chlorzoxazone + NADPH + H+ <=> H2O + NADP+ + 6-Hydroxy-chlorzoxazone not assigned
 –
acetophenone + NADPH + H+ <=> 1-Acenaphthenol + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
NADPH + D-arabinose + H+ <=> NADP+ + D-arabitol 1.1.1.21 aldose reductase
–
21-dehydrocortisone + H+ + NADPH <=> NADP+ + cortisone 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
NADPH + 21-dehydrocorticosterone + H+ <=> NADP+ + corticosterone 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
2 NADPH + (1S)-Camphorquinone + 2 H+ <=> 1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + 2 NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
2 NADPH + 2 H+ + (1R)-(-)-Camphorquinone <=> 1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + 2 NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
2 H+ + 2 NADPH + 2,3-Pentanedione <=> 2 NADP+ + 2,3-pentanediol 1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
NADPH + H+ + 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione <=> NADP+ + 6-tert-Butyl-2,3-epoxy-4-hydroxy-5-cyclohexene-1-one 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
3alpha,17alpha,21-trihydroxy-5beta-pregnan-11,20-dione + NADP+ <=> Dihydrocortisone + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
adamantanone + NADPH + H+ <=> 1-Adamantanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
H+ + NADPH + D-erythrose_4-phosphate <=> NADP+ + D-erythritol_4-phosphate 1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+)
–
NADP+ + trans-1,2-Dihydronaphthalene-1,2-diol <=> H+ + 1,2-dihydroxynaphthalene + NADPH 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
H+ + D-ribose_5-phosphate + NADPH <=> NADP+ + D-ribitol_5-phosphate 1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+)
–
2-acetylpyrrole + H+ + O2 + NADPH <=> 1H-pyrrol-2-yl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
O2 + 4-aminoacetophenone + NADPH + H+ <=> NADP+ + H2O + (4-Aminophenyl)acetate 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
2 (6E)-8-hydroxygeraniol + 2 NADP+ <=> 2 NADPH + 2 H+ + (6E)-8-oxogeraniol + (6E)-8-hydroxygeranial 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
NADP+ + trans-2-Heptenol <=> heptenal + H+ + NADPH 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
2 H+ + 2 NADPH + Methyl_red <=> 2 NADP+ + N,N-dimethyl-1,4-phenylenediamine + anthranilate 1.7.1.6 azobenzene reductase
–
NADPH + 2-dehydro-D-glucose + H+ <=> D-mannose + NADP+ 1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
–
O2 + NADPH + H+ + abietadienal <=> NADP+ + 2 H2O + abietic_acid 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase
–
isopimaradienal + O2 + H+ + NADPH <=> 2 H2O + (13S)-pimara-7,15-dien-18-oate + NADP+ 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase
–
dehydroabietadienal + NADPH + H+ + O2 <=> NADP+ + Dehydroabietic_acid + 2 H2O 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase
–
isopimara-7,15-dienol + NADPH + O2 + H+ <=> isopimaradienal + NADP+ + 2 H2O 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase
–
O2 + NADPH + H+ + dehydroabietadienol <=> dehydroabietadienal + NADP+ + 2 H2O 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase
–
NADPH + H+ + O2 + abietadienol <=> 2 H2O + NADP+ + abietadienal 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase
–
NADPH + H+ + O2 + levopimaradienol <=> NADP+ + 2 H2O + levopimaradienal 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase
–
NADP+ + D-talose <=> D-talono-1,4-lactone + H+ + NADPH 1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
–
NADPH + O2 + tazarotenic_acid <=> Tazarotenic_acid_sulfoxide + H+ + NADP+ + H2O not assigned
 –
NADPH + 9-cis-retinoic_acid + O2 <=> NADP+ + H+ + H2O + 9-cis-4-Hydroxyretinoic_acid not assigned
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NADP+ + (-)-borneol <=> H+ + (-)-Camphor + NADPH not assigned
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2,4-Dimethyl-3-pentanone + NADPH + H+ <=> NADP+ + 2,4-Dimethyl-3-pentanol not assigned
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retinoic_acid + NADPH + O2 + H+ <=> 3-Hydroxyretinoic_acid + NADP+ + H2O not assigned
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retinoic_acid + NADPH + H+ + O2 <=> NADP+ + 18-Hydroxyretinoic_acid + H2O not assigned
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H+ + NADPH + 3-methyl-2-oxopentanoate <=> 2-hydroxyisocaproate + NADP+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
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L-ribulose + H+ + NADPH <=> ribitol + NADP+ 1.1.1.10 L-xylulose reductase
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NADPH + 3-Dehydroecdysone + H+ <=> NADP+ + ecdysone not assigned
 –
Isopropylbenzaldehyde + H+ + NADPH <=> NADP+ + 2-Isopropylbenzyl_alcohol not assigned
 –
O2 + paclitaxel + NADPH <=> NADP+ + 6-alpha-Hydroxypaclitaxel + H2O 1.14.14.1 unspecific monooxygenase
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amodiaquine + O2 + NADPH <=> N-desethylamodiaquine + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
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O2 + aniline + NADPH + H+ <=> NADP+ + H2O + 4-Aminophenol 1.14.14.1 unspecific monooxygenase
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H+ + NADPH + O2 + Biochanin_A <=> H2O + NADP+ + 3''-Hydroxybiochanin_A 1.14.14.88 isoflavone 3'-hydroxylase
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NADPH + H+ + O2 + aminopyrine <=> aminopyrine + H2O + formaldehyde + NADP+ 1.14.14.1 unspecific monooxygenase
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NADPH + O2 + all-trans-retinol + H+ <=> H2O + NADP+ + all-trans-retinal 1.14.14.1 unspecific monooxygenase
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H+ + O2 + all-trans-retinal + NADPH <=> retinoic_acid + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
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3 NADPH + 3 O2 + 9beta-pimara-7,15-diene <=> 3 NADP+ + 4 H2O + 9beta-pimara-7,15-dien-19-oate 1.14.14.111 9beta-pimara-7,15-diene oxidase
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H+ + O2 + 7-Benzyloxy-4-trifluoromethylcoumarin + NADPH <=> NADP+ + 7-hydroxy-4-trifluoromethylcoumarin + benzaldehyde 1.14.14.1 unspecific monooxygenase
–
(rac)_fenthion_sulfoxide + H+ + NADPH + O2 <=> H2O + NADP+ + fenthion-sulfone 1.14.14.1 unspecific monooxygenase
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O2 + NADPH + 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine + H+ <=> H2O + N-hydroxy-2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine + NADP+ 1.14.14.1 unspecific monooxygenase
–
NADPH + 2-amino-3-methylimidazo[4,5-f]quinoline + H+ + O2 <=> 2-Hydroxyamino-3-methylimidazo[4,5-f]quinoline + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
O2 + NADPH + H+ + 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline <=> H2O + N-hydroxy-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline + NADP+ 1.14.14.1 unspecific monooxygenase
–
2 NADPH + 2 O2 + L-tryptophan + 2 H+ <=> 3 H2O + CO2 + 2 NADP+ + (E,Z)-indolyl-3-acetaldoxime 1.14.14.156 tryptophan N-monooxygenase
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17beta-estradiol + H+ + NADPH + O2 <=> 4-hydroxyestradiol + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
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2 H+ + 2 O2 + 2 NADPH + L-valine <=> Isobutyraldoxime + 2 NADP+ + 3 H2O + CO2 1.14.14.38 valine N-monooxygenase
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L-isoleucine + 2 O2 + 2 NADPH + 2 H+ <=> 2 NADP+ + CO2 + N-hydroxy-L-isoleucine + 3 H2O 1.14.14.38 valine N-monooxygenase
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H+ + 5beta-androstane-3alpha-ol-17-one + NADPH <=> NADP+ + androstanediol 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
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dehydroepiandrosterone_3-sulfate + H+ + NADPH <=> NADP+ + Androstenediol_sulfate 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
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4-coumaroylshikimate + H+ + NADPH + O2 <=> NADP+ + 5-O-Caffeoylshikimic_acid + H2O not assigned
 –
2 O2 + 2 H+ + 2 NADPH + L-phenylalanine <=> CO2 + 3 H2O + 2 NADP+ + (E)-phenylacetaldoxime 1.14.14.40 phenylalanine N-monooxygenase
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hematoheme + 3 NADPH + 3 O2 <=> 3 H2O + 3 NADP+ + CO + Hematobiliverdin + Fe2+ 1.14.14.18 heme oxygenase (biliverdin-producing)
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Hematin + 3 O2 + 3 NADPH <=> 3 NADP+ + Biliverdin + Fe2+ + 3 H2O + CO 1.14.14.18 heme oxygenase (biliverdin-producing)
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2-benzoylpyridine + NADPH + H+ <=> NADP+ + 3alpha-hydroxybenzylpyridine 1.1.1.21 aldose reductase
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7-methoxyresorufin + NADPH + H+ + O2 <=> NADP+ + methanol + resorufin 1.14.14.1 unspecific monooxygenase
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NADP+ + Glutaraldehyde + H2O <=> H+ + NADPH + 5-Oxopentanoate 1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
–
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NADPH + (24S)-24-hydroxycholesterol + O2 + H+ <=> H2O + Dihydroxycholesterol + NADP+ 1.14.14.25 cholesterol 24-hydroxylase
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H+ + O2 + dextromethorphan + NADPH <=> Dextrorphan + NADP+ + H2O 1.14.14.25 cholesterol 24-hydroxylase
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testosterone + NADPH + H+ + O2 <=> H2O + 16beta-Hydroxytestosterone + NADP+ 1.14.14.25 cholesterol 24-hydroxylase
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H+ + NADPH + diclofenac + O2 <=> 4''-Hydroxydiclofenac + H2O + NADP+ 1.14.14.25 cholesterol 24-hydroxylase
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NADPH + H+ + O2 + testosterone <=> NADP+ + 2-Hydroxytestosterone + H2O 1.14.14.25 cholesterol 24-hydroxylase
–
H+ + NADPH + O2 + Phenacetin <=> ethanol + acetaminophen + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
1.14.14.25 cholesterol 24-hydroxylase
–
–
NADPH + 5beta-Pregnan-3beta-ol-20-one + H+ <=> NADP+ + 5beta-pregnan-3beta,20alpha-diol 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
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NADPH + 1,4-androstadien-17beta-ol-3-one + H+ <=> NADP+ + 5beta-Androst-1-en-17beta-ol-3-one 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
O2 + dimethylnitrosamine + NADPH <=> NADP+ + H2O + formaldehyde + N-Nitrosomethanamine not assigned
 –
Tolbutamide + O2 + NADPH + H+ <=> Hydroxytolbutamide + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
mephenytoin + H+ + O2 + NADPH <=> H2O + 4-Hydroxymephenytoin + NADP+ not assigned
 –
H+ + O2 + NADPH + progesterone <=> 6beta-Hydroxyprogesterone + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
H+ + O2 + NADPH + progesterone <=> H2O + 16alpha-hydroxyprogesterone + NADP+ 1.14.14.1 unspecific monooxygenase
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3-hydroxycinnamic_acid + NADPH + H+ + O2 <=> caffeic_acid + NADP+ + H2O 1.14.14.91 trans-cinnamate 4-monooxygenase
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O2 + 2-methoxycinnamate + H+ + NADPH <=> (2E)-3-(4-hydroxy-2-methoxyphenyl)prop-2-enoic_acid + H2O + NADP+ 1.14.14.91 trans-cinnamate 4-monooxygenase
–
(2E)-3-(2-nitrophenyl)prop-2-enoic_acid + NADPH + O2 + H+ <=> H2O + NADP+ + 2-Nitro-4-hydroxycinnamate 1.14.14.91 trans-cinnamate 4-monooxygenase
–
cholesterol + NADP+ <=> H+ + 5-Cholesten-3-one + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
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2-fluorocinnamic_acid + O2 + NADPH + H+ <=> (E)-2-fluoro-4-hydroxycinnamate + NADP+ + H2O 1.14.14.91 trans-cinnamate 4-monooxygenase
–
H+ + NADPH + O2 + 2-chlorocinnamic_acid <=> NADP+ + H2O + (2E)-3-(2-chloro-4-hydroxyphenyl)prop-2-enoic_acid 1.14.14.91 trans-cinnamate 4-monooxygenase
–
3-deoxyglucosone + H+ + NADPH <=> NADP+ + 3-Deoxy-D-glucosone 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
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Flucloxacillin + NADPH + O2 + H+ <=> H2O + NADP+ + 5-Hydroxymethylflucloxacillin not assigned
 –
NADPH + tert-butyl_hydroperoxide + H+ <=> tert-butanol + NADP+ + H2O 1.11.1.21 catalase-peroxidase
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3-hydroxy-2-oxobutanoate + H+ + NADPH <=> NADP+ + Tartrate 1.1.1.86 ketol-acid reductoisomerase (NADP+)
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2-oxoglutarate + NADPH + H+ <=> NADP+ + 2-hydroxyglutarate 1.1.1.42 isocitrate dehydrogenase (NADP+)
–